BR112014014947A2 - produção acentuada de isopreno com o uso de células hospedeiras tendo atividade de ispa diminuida - Google Patents

produção acentuada de isopreno com o uso de células hospedeiras tendo atividade de ispa diminuida Download PDF

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Publication number
BR112014014947A2
BR112014014947A2 BR112014014947-0A BR112014014947A BR112014014947A2 BR 112014014947 A2 BR112014014947 A2 BR 112014014947A2 BR 112014014947 A BR112014014947 A BR 112014014947A BR 112014014947 A2 BR112014014947 A2 BR 112014014947A2
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BR
Brazil
Prior art keywords
polypeptide
isoprene
cells
ispa
activity
Prior art date
Application number
BR112014014947-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Joseph C. McAuliffe
Rachel E. MUIR
Alex T. Nielsen
Caroline M. Peres
Dmitrii V. Vaviline
Derek H. Wells
Original Assignee
Danisco Us Inc.
The Goodyear Tire & Rubber Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc., The Goodyear Tire & Rubber Company filed Critical Danisco Us Inc.
Publication of BR112014014947A2 publication Critical patent/BR112014014947A2/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1085Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y205/00Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01001Dimethylallyltranstransferase (2.5.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/03Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03027Isoprene synthase (4.2.3.27)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR112014014947-0A 2011-12-23 2012-12-21 produção acentuada de isopreno com o uso de células hospedeiras tendo atividade de ispa diminuida BR112014014947A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161580163P 2011-12-23 2011-12-23
US61/580,163 2011-12-23
US201261639855P 2012-04-27 2012-04-27
US61/639,855 2012-04-27
PCT/US2012/071518 WO2013096925A1 (en) 2011-12-23 2012-12-21 Enhanced production of isoprene using host cells having decreased ispa activity

Publications (1)

Publication Number Publication Date
BR112014014947A2 true BR112014014947A2 (pt) 2020-10-27

Family

ID=47522963

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014014947-0A BR112014014947A2 (pt) 2011-12-23 2012-12-21 produção acentuada de isopreno com o uso de células hospedeiras tendo atividade de ispa diminuida

Country Status (10)

Country Link
US (2) US8975051B2 (enExample)
EP (1) EP2794863A1 (enExample)
JP (1) JP2015510392A (enExample)
CN (1) CN104245927A (enExample)
AU (1) AU2012358149A1 (enExample)
BR (1) BR112014014947A2 (enExample)
CA (1) CA2859885A1 (enExample)
MX (1) MX2014007623A (enExample)
SG (1) SG11201403163QA (enExample)
WO (1) WO2013096925A1 (enExample)

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WO2014027118A1 (en) * 2012-08-17 2014-02-20 Evolva Sa Increased production of terpenes and terpenoids
WO2015083769A1 (ja) * 2013-12-04 2015-06-11 国立研究開発法人理化学研究所 光合成のみによるポリヒドロキシアルカン酸の生産
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
JP2018014960A (ja) * 2016-07-29 2018-02-01 横浜ゴム株式会社 発現ベクター、形質転換された藻類、形質転換された珪藻、及び、ポリヌクレオチド
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
WO2018208116A1 (ko) * 2017-05-11 2018-11-15 경상대학교산학협력단 형질전환 생물체 선별용 마커 조성물, 형질전환 생물체 및 형질전환 방법
US11549117B2 (en) 2017-05-11 2023-01-10 Industry-Academic Cooperation Foundation Gyeongsang National University Marker composition for selecting living modified organism, living modified organism, and transformation method
CN110317765B (zh) * 2018-03-29 2020-11-20 中国科学院天津工业生物技术研究所 一种高产香叶醇葡萄糖苷的大肠杆菌表达菌株及其应用
BR112021010079A2 (pt) 2018-11-27 2021-11-23 Khona Scient Llc Armações multienzimáticas bidirecionais para a biossíntese de canabinoides
US12351850B2 (en) 2020-04-30 2025-07-08 Sutro Biopharma, Inc. Methods of producing full-length antibodies using E. coli
CN112553134B (zh) * 2020-12-30 2022-09-06 江南大学 一种在枯草芽孢杆菌中表达α-淀粉酶的方法

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WO2003095651A1 (fr) 2002-05-10 2003-11-20 Kyowa Hakko Kogyo Co., Ltd. Procede de production d'acide mevalonique
JP4592418B2 (ja) 2002-10-04 2010-12-01 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 高収率での1,3−プロパンジオールの生物生産のための方法
RU2004124226A (ru) 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Использование фосфокетолазы для продукции полезных метаболитов
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SG162265A1 (en) * 2007-12-13 2010-07-29 Danisco Us Inc Compositions and methods for producing isoprene
US20110045563A1 (en) 2008-02-06 2011-02-24 The Regents Of The University Of California Short chain volatile isoprene hydrocarbon production using the mevalonic acid pathway in genetically engineered yeast and fungi
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BR112012014736B1 (pt) 2009-12-18 2018-09-18 Danisco Us Inc método para purificação de isopreno a partir de um efluente gasoso do fermentador e composição
BR112012017345A2 (pt) * 2009-12-23 2015-11-03 Danisco Us Inc "composições e métodos de pgl para a produção aumentada de isopreno e outros produtos com 6-fosfogliconolactonase (pgl)"
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Also Published As

Publication number Publication date
AU2012358149A1 (en) 2014-07-03
US20150218590A1 (en) 2015-08-06
WO2013096925A1 (en) 2013-06-27
EP2794863A1 (en) 2014-10-29
CA2859885A1 (en) 2013-06-27
US9388431B2 (en) 2016-07-12
MX2014007623A (es) 2015-02-04
CN104245927A (zh) 2014-12-24
US20130164808A1 (en) 2013-06-27
SG11201403163QA (en) 2014-09-26
US8975051B2 (en) 2015-03-10
JP2015510392A (ja) 2015-04-09

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B350 Update of information on the portal [chapter 15.35 patent gazette]