MX2013011721A - Metodos para tratar condiciones asociadas con la activacion del complemento dependiente de masp-2. - Google Patents

Metodos para tratar condiciones asociadas con la activacion del complemento dependiente de masp-2.

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Publication number
MX2013011721A
MX2013011721A MX2013011721A MX2013011721A MX2013011721A MX 2013011721 A MX2013011721 A MX 2013011721A MX 2013011721 A MX2013011721 A MX 2013011721A MX 2013011721 A MX2013011721 A MX 2013011721A MX 2013011721 A MX2013011721 A MX 2013011721A
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MX
Mexico
Prior art keywords
masp
complement activation
dependent complement
methods
dependent
Prior art date
Application number
MX2013011721A
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English (en)
Other versions
MX339002B (es
Inventor
Hans-Wilhelm Schwaeble
Gregory A Demopulos
Tom Dudler
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Omeros Corp
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Publication date
Application filed by Omeros Corp filed Critical Omeros Corp
Publication of MX2013011721A publication Critical patent/MX2013011721A/es
Publication of MX339002B publication Critical patent/MX339002B/es

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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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Abstract

En un aspecto, la invención proporciona métodos para inhibir los efectos de la activación de complemento dependiente de MASP-2 en un sujeto vivo. Los métodos comprenden los pasos de administrar, a un sujeto en necesidad del mismo, una cantidad eficaz de un agente inhibidor de MASP-2 para inhibir la activación del complemento dependiente de MASP-2. En algunas modalidades, el agente inhibidor de MASP-2 inhibe la lesión celular asociada con la activación de la vía del complemento alternativa mediada por MASP-2, mientras deja al componente de la vía clásica (dependiente de C1q) intacta. En otro aspecto, la invención proporciona composiciones para inhibir los efectos de la activación de complemento dependiente de lectina, comprendiendo una cantidad terapéuticamente eficaz de un agente inhibidor de MASP-2 y un vehículo farmacéuticamente aceptable.
MX2013011721A 2011-04-08 2012-04-06 El uso de un agente inhibidor de masp-2 para tratar condiciones asociadas con la activacion del complemento dependiente de masp-2. MX339002B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161473698P 2011-04-08 2011-04-08
PCT/US2012/032650 WO2012139081A2 (en) 2011-04-08 2012-04-06 Methods for treating conditions associated with masp-2 dependent complement activation

Publications (2)

Publication Number Publication Date
MX2013011721A true MX2013011721A (es) 2014-03-05
MX339002B MX339002B (es) 2016-05-06

Family

ID=46966283

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013011721A MX339002B (es) 2011-04-08 2012-04-06 El uso de un agente inhibidor de masp-2 para tratar condiciones asociadas con la activacion del complemento dependiente de masp-2.
MX2016006039A MX355648B (es) 2011-04-08 2012-04-06 El uso de un agente inhibidor de masp-2 para tratar condiciones asociadas con la activacion del complemento dependiente de masp-2.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2016006039A MX355648B (es) 2011-04-08 2012-04-06 El uso de un agente inhibidor de masp-2 para tratar condiciones asociadas con la activacion del complemento dependiente de masp-2.

Country Status (18)

Country Link
US (5) US8951522B2 (es)
EP (3) EP2694108B1 (es)
JP (4) JP5937197B2 (es)
KR (6) KR20180072851A (es)
CN (3) CN103781492A (es)
AU (1) AU2012239889B2 (es)
BR (1) BR112013025917A2 (es)
CA (4) CA3076975C (es)
CL (1) CL2013002874A1 (es)
DK (2) DK2694108T3 (es)
ES (2) ES2683307T3 (es)
HK (1) HK1250342A1 (es)
IL (3) IL228758B (es)
MX (2) MX339002B (es)
NZ (5) NZ731596A (es)
PL (1) PL3287142T3 (es)
RU (2) RU2743409C2 (es)
WO (1) WO2012139081A2 (es)

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