MX2012009313A - Metodos y composiciones para mejorar la resistencia mecanica de los dientes. - Google Patents
Metodos y composiciones para mejorar la resistencia mecanica de los dientes.Info
- Publication number
- MX2012009313A MX2012009313A MX2012009313A MX2012009313A MX2012009313A MX 2012009313 A MX2012009313 A MX 2012009313A MX 2012009313 A MX2012009313 A MX 2012009313A MX 2012009313 A MX2012009313 A MX 2012009313A MX 2012009313 A MX2012009313 A MX 2012009313A
- Authority
- MX
- Mexico
- Prior art keywords
- composition
- phosphate
- combinations
- theobromine
- hardness
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 118
- 238000000034 method Methods 0.000 title claims abstract description 65
- 208000002925 dental caries Diseases 0.000 claims abstract description 29
- YAPQBXQYLJRXSA-UHFFFAOYSA-N theobromine Chemical compound CN1C(=O)NC(=O)C2=C1N=CN2C YAPQBXQYLJRXSA-UHFFFAOYSA-N 0.000 claims description 218
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims description 126
- 229960004559 theobromine Drugs 0.000 claims description 106
- 239000011775 sodium fluoride Substances 0.000 claims description 63
- 235000013024 sodium fluoride Nutrition 0.000 claims description 63
- 238000011282 treatment Methods 0.000 claims description 33
- 238000007373 indentation Methods 0.000 claims description 30
- 239000000551 dentifrice Substances 0.000 claims description 29
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 22
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 22
- 239000011575 calcium Substances 0.000 claims description 21
- 239000001506 calcium phosphate Substances 0.000 claims description 21
- XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 claims description 20
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 20
- 229960004711 sodium monofluorophosphate Drugs 0.000 claims description 20
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 20
- 229910052791 calcium Inorganic materials 0.000 claims description 18
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- 235000011010 calcium phosphates Nutrition 0.000 claims description 18
- 150000003839 salts Chemical class 0.000 claims description 18
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 17
- 229960005069 calcium Drugs 0.000 claims description 17
- 229910019142 PO4 Inorganic materials 0.000 claims description 16
- 239000010452 phosphate Substances 0.000 claims description 16
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 16
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- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims description 6
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 6
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- 235000013927 calcium gluconate Nutrition 0.000 claims description 6
- 229960004494 calcium gluconate Drugs 0.000 claims description 6
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 claims description 6
- 239000010634 clove oil Substances 0.000 claims description 6
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 claims description 6
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- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Dental Preparations (AREA)
- Medicinal Preparation (AREA)
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| US30377410P | 2010-02-12 | 2010-02-12 | |
| PCT/US2011/024734 WO2011100671A2 (en) | 2010-02-12 | 2011-02-14 | Methods and compositions to improve mechanical resistance of teeth |
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| MX2012009313A true MX2012009313A (es) | 2012-11-06 |
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| MX2012009313A MX2012009313A (es) | 2010-02-12 | 2011-02-14 | Metodos y composiciones para mejorar la resistencia mecanica de los dientes. |
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| EP (1) | EP2533786B1 (enExample) |
| JP (1) | JP6114036B2 (enExample) |
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| WO (1) | WO2011100671A2 (enExample) |
| ZA (1) | ZA201206742B (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2007214265B2 (en) | 2006-02-09 | 2012-06-14 | The University Of Melbourne | Fluoride composition and methods for dental mineralization |
| CN102821768A (zh) | 2010-02-12 | 2012-12-12 | 斯欧考普控股公司 | 提高牙齿的机械抗性的方法和组合物 |
| HK1207992A1 (en) * | 2012-06-20 | 2016-02-19 | 斯欧考普控股公司 | Compositions containing theobromine and their use in treating tooth hypersensitivity |
| US9937184B2 (en) * | 2013-03-15 | 2018-04-10 | Theocorp Holding Company, Llc | Theobromine compositions useful for increasing fetal weight gain and enhancing bone properties |
| PL3024428T3 (pl) | 2013-07-23 | 2021-07-05 | The University Of Melbourne | Kompozycje i sposoby mineralizacji zębów |
| FR3011466A1 (fr) * | 2013-10-09 | 2015-04-10 | Roquette Freres | Utilisation d'un polyol dans la remineralisation de l'email |
| RU2716134C2 (ru) | 2013-12-24 | 2020-03-06 | Де Юниверсити Оф Мельбурн | Стабилизированные композиции на основе олова (II) |
| KR102187824B1 (ko) * | 2014-03-26 | 2020-12-07 | 주식회사 엘지생활건강 | 치면 부착용 겔 조성물 및 이를 포함하는 키트 |
| RU2720242C2 (ru) * | 2014-12-24 | 2020-04-28 | Юниверсити Оф Мельбурн | Минерализующие фторсодержащие композиции |
| KR102862249B1 (ko) | 2017-03-14 | 2025-09-19 | 더 유니버시티 오브 멜버른 | 치은염을 위한 치료 |
| EA201991935A1 (ru) | 2017-03-14 | 2020-02-14 | Де Юниверсити Оф Мельбурн | Комплексы для лечения чувствительности |
| CA3133097A1 (en) | 2019-03-13 | 2020-09-17 | The University Of Melbourne | Compositions and methods for promoting mineralization |
| CN110917210B (zh) * | 2019-12-27 | 2022-04-19 | 安徽医科大学 | 一种牙齿矿化漂白双功能糊剂、制备方法及应用 |
| CN112094699B (zh) * | 2020-09-27 | 2023-03-28 | 广西壮族自治区林业科学研究院 | 一种樟树纯露的提取方法 |
| DE102021111354A1 (de) * | 2021-05-03 | 2022-11-03 | Dr. Kurt Wolff Gmbh & Co. Kg | Mundpflegemittel |
| DE102021111387A1 (de) | 2021-05-03 | 2022-11-03 | Dr. Kurt Wolff Gmbh & Co. Kg | Oralgel-Zusammensetzung und ihre Verwendung |
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| DE4007431A1 (de) * | 1990-03-09 | 1991-09-12 | Henkel Kgaa | Den zahnschmelz schuetzende mund- und zahnpflegemittel |
| US5626838A (en) * | 1995-03-13 | 1997-05-06 | The Procter & Gamble Company | Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx |
| US5571502A (en) * | 1995-08-08 | 1996-11-05 | Enamelon Research | Stable single-part compositions and the use thereof for remineralization of lesions in teeth |
| US6183711B1 (en) * | 1995-12-27 | 2001-02-06 | Tetsuo Nakamoto | Apatite-forming-systems: methods and products |
| US20050054682A1 (en) * | 1996-01-04 | 2005-03-10 | Phillips Jeffrey O. | Pharmaceutical compositions comprising substituted benzimidazoles and methods of using same |
| JP3719874B2 (ja) * | 1998-04-24 | 2005-11-24 | サンスター株式会社 | 口腔用組成物 |
| US6685920B2 (en) * | 1999-11-12 | 2004-02-03 | The Procter & Gamble Company | Method of protecting teeth against erosion |
| KR20030032484A (ko) * | 2001-10-18 | 2003-04-26 | 롯데제과주식회사 | 발암 억제효능을 갖는 데오브로민 |
| AU2003241807A1 (en) * | 2002-05-27 | 2003-12-12 | Morinaga And Co., Ltd. | Composition against periodontal bacteria and foods, drinks and mouth washers against periodontal bacteria containing the composition |
| US20050152852A1 (en) * | 2002-05-27 | 2005-07-14 | Morinaga & Co., Ltd. | Use of antibacterial component extracted from cacao mass for inhibiting the growth of periodontal bacteria |
| US6953817B2 (en) * | 2002-08-05 | 2005-10-11 | Colgate-Palmolive Company | Dual component dentinal desensitizing dentifrice |
| US20040034042A1 (en) * | 2002-08-14 | 2004-02-19 | Masao Tsuji | Preservative composition |
| EP1604671A4 (en) * | 2003-02-26 | 2006-03-29 | Kyowa Hakko Kogyo Kk | MUSCLE TREATMENT AND MEANS FOR PREVENTING OR TREATING MUSCLE WEAKNESS |
| DE102004041496A1 (de) | 2004-08-27 | 2006-03-02 | Symrise Gmbh & Co. Kg | Hydroxybenzoesäureamide und deren Verwendung zur Maskierung von bitterem Geschmack |
| JP4820320B2 (ja) * | 2006-03-28 | 2011-11-24 | 花王株式会社 | 口腔用組成物 |
| JP5633998B2 (ja) * | 2006-09-27 | 2014-12-03 | 三栄源エフ・エフ・アイ株式会社 | 歯の再石灰化促進剤およびこれを含む口腔または経口用組成物 |
| JP5354865B2 (ja) * | 2007-03-30 | 2013-11-27 | 太陽化学株式会社 | リン酸カルシウム溶解抑制剤 |
| JP5553396B2 (ja) * | 2007-04-10 | 2014-07-16 | 株式会社サンギ | 再石灰化促進剤及び口腔用組成物 |
| AU2008308951B2 (en) * | 2007-10-01 | 2012-07-26 | Colgate-Palmolive Company | Oral compositions containing botanical extracts |
| JP5196127B2 (ja) * | 2007-12-19 | 2013-05-15 | ライオン株式会社 | 口腔用組成物 |
| JP5656368B2 (ja) | 2009-05-29 | 2015-01-21 | 花王株式会社 | 歯磨剤 |
| CN102821768A (zh) | 2010-02-12 | 2012-12-12 | 斯欧考普控股公司 | 提高牙齿的机械抗性的方法和组合物 |
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- 2011-02-14 RU RU2012133316/15A patent/RU2591084C2/ru not_active Application Discontinuation
- 2011-02-14 AU AU2011215617A patent/AU2011215617B2/en not_active Ceased
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- 2011-02-14 SG SG10201500795WA patent/SG10201500795WA/en unknown
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2012
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Also Published As
| Publication number | Publication date |
|---|---|
| US9610235B2 (en) | 2017-04-04 |
| US20130129641A1 (en) | 2013-05-23 |
| AU2011215617A1 (en) | 2012-09-13 |
| WO2011100671A3 (en) | 2011-12-22 |
| IL221403A0 (en) | 2012-10-31 |
| WO2011100671A2 (en) | 2011-08-18 |
| SG183277A1 (en) | 2012-09-27 |
| KR20120123534A (ko) | 2012-11-08 |
| CN102821768A (zh) | 2012-12-12 |
| JP2013519688A (ja) | 2013-05-30 |
| ES2617758T3 (es) | 2017-06-19 |
| CA2789595C (en) | 2017-11-28 |
| CA2789595A1 (en) | 2011-08-18 |
| NZ601989A (en) | 2014-11-28 |
| RU2591084C2 (ru) | 2016-07-10 |
| JP6114036B2 (ja) | 2017-04-12 |
| EP2533786A4 (en) | 2013-06-12 |
| AU2011215617B2 (en) | 2016-01-28 |
| CN106668064A (zh) | 2017-05-17 |
| SG10201500795WA (en) | 2015-04-29 |
| RU2012133316A (ru) | 2014-03-20 |
| EP2533786B1 (en) | 2016-12-28 |
| BR112012019844A2 (pt) | 2017-12-05 |
| ZA201206742B (en) | 2013-05-29 |
| EP2533786A2 (en) | 2012-12-19 |
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