CN102821768A - 提高牙齿的机械抗性的方法和组合物 - Google Patents

提高牙齿的机械抗性的方法和组合物 Download PDF

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Publication number
CN102821768A
CN102821768A CN2011800104594A CN201180010459A CN102821768A CN 102821768 A CN102821768 A CN 102821768A CN 2011800104594 A CN2011800104594 A CN 2011800104594A CN 201180010459 A CN201180010459 A CN 201180010459A CN 102821768 A CN102821768 A CN 102821768A
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composition
phosphate
hardness
theobromine
calcium
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CN2011800104594A
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English (en)
Chinese (zh)
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A·赛之霍普尔
中本哲夫
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THEOCORP HOLDING CO LLC
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THEOCORP HOLDING CO LLC
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Priority to CN201710170152.XA priority Critical patent/CN106668064A/zh
Publication of CN102821768A publication Critical patent/CN102821768A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A61K8/21—Fluorides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Medicinal Preparation (AREA)
CN2011800104594A 2010-02-12 2011-02-14 提高牙齿的机械抗性的方法和组合物 Pending CN102821768A (zh)

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CN201710170152.XA CN106668064A (zh) 2010-02-12 2011-02-14 提高牙齿的机械抗性的方法和组合物

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US30377410P 2010-02-12 2010-02-12
US61/303,774 2010-02-12
PCT/US2011/024734 WO2011100671A2 (en) 2010-02-12 2011-02-14 Methods and compositions to improve mechanical resistance of teeth

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US (1) US9610235B2 (enExample)
EP (1) EP2533786B1 (enExample)
JP (1) JP6114036B2 (enExample)
KR (1) KR20120123534A (enExample)
CN (2) CN102821768A (enExample)
AU (1) AU2011215617B2 (enExample)
BR (1) BR112012019844A2 (enExample)
CA (1) CA2789595C (enExample)
ES (1) ES2617758T3 (enExample)
IL (1) IL221403A0 (enExample)
MX (1) MX2012009313A (enExample)
NZ (1) NZ601989A (enExample)
RU (1) RU2591084C2 (enExample)
SG (2) SG183277A1 (enExample)
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105189736A (zh) * 2013-03-15 2015-12-23 斯欧考普控股公司 适用于提高胎儿体重增加并增强骨特性的可可碱组合物
CN105611911A (zh) * 2013-10-09 2016-05-25 罗盖特公司 多元醇在牙釉质再矿化中的用途
CN107427700A (zh) * 2014-12-24 2017-12-01 墨尔本大学 矿化氟化物组合物
CN110917210A (zh) * 2019-12-27 2020-03-27 安徽医科大学 一种牙齿矿化漂白双功能糊剂、制备方法及应用

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2705826T3 (pl) 2006-02-09 2020-11-02 The University Of Melbourne Kompozycja fluorku i sposoby mineralizacji zębów
BR112012019844A2 (pt) 2010-02-12 2017-12-05 Theocorp Holding Co Llc metodos e composições para melhorar a resistência mecânica dos dentes
US9962325B2 (en) 2012-06-20 2018-05-08 Theocorp Holding Co., Llc Compositions containing theobromine and their use in treating tooth hypersensitivity
WO2015010166A1 (en) 2013-07-23 2015-01-29 The University Of Melbourne Compositions and methods for dental mineralization
WO2015095932A1 (en) 2013-12-24 2015-07-02 The University Of Melbourne Stabilized stannous compositions
KR102187824B1 (ko) * 2014-03-26 2020-12-07 주식회사 엘지생활건강 치면 부착용 겔 조성물 및 이를 포함하는 키트
CA3055091A1 (en) 2017-03-14 2018-09-20 The University Of Melbourne Treatment for gingivitis
BR112019018871A2 (pt) 2017-03-14 2020-04-14 Univ Melbourne complexos para tratar sensibilidade
CN112094699B (zh) * 2020-09-27 2023-03-28 广西壮族自治区林业科学研究院 一种樟树纯露的提取方法
DE102021111387A1 (de) 2021-05-03 2022-11-03 Dr. Kurt Wolff Gmbh & Co. Kg Oralgel-Zusammensetzung und ihre Verwendung
DE102021111354A1 (de) * 2021-05-03 2022-11-03 Dr. Kurt Wolff Gmbh & Co. Kg Mundpflegemittel

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US5626838A (en) * 1995-03-13 1997-05-06 The Procter & Gamble Company Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx
US5919426A (en) * 1995-12-27 1999-07-06 Biomedical Development Corporation Products of apatite-forming-systems
US20050054682A1 (en) * 1996-01-04 2005-03-10 Phillips Jeffrey O. Pharmaceutical compositions comprising substituted benzimidazoles and methods of using same
US20050152852A1 (en) * 2002-05-27 2005-07-14 Morinaga & Co., Ltd. Use of antibacterial component extracted from cacao mass for inhibiting the growth of periodontal bacteria
US20060189566A1 (en) * 2003-02-26 2006-08-24 Miho Komatsu Muscle building agent and preventive or remedy for muscle weakening
US20080214675A1 (en) * 2004-08-27 2008-09-04 Symrise Gmbh & Co. Kg Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste
US20090087501A1 (en) * 2007-10-01 2009-04-02 Colgate-Palmolive Company Oral Compositions Containing Botanical Extracts

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DE4007431A1 (de) * 1990-03-09 1991-09-12 Henkel Kgaa Den zahnschmelz schuetzende mund- und zahnpflegemittel
US5571502A (en) * 1995-08-08 1996-11-05 Enamelon Research Stable single-part compositions and the use thereof for remineralization of lesions in teeth
JP3719874B2 (ja) * 1998-04-24 2005-11-24 サンスター株式会社 口腔用組成物
US6685920B2 (en) * 1999-11-12 2004-02-03 The Procter & Gamble Company Method of protecting teeth against erosion
KR20030032484A (ko) * 2001-10-18 2003-04-26 롯데제과주식회사 발암 억제효능을 갖는 데오브로민
EP1508335B1 (en) * 2002-05-27 2011-09-28 Morinaga & Co. Ltd. Compositions comprising a cocoa fraction for use in the treatment of periodontitis caused by bacteria belonging to genus porphyromonas, prevotella, fusobacterium or actinobacillus
US6953817B2 (en) * 2002-08-05 2005-10-11 Colgate-Palmolive Company Dual component dentinal desensitizing dentifrice
US20040034042A1 (en) * 2002-08-14 2004-02-19 Masao Tsuji Preservative composition
JP4820320B2 (ja) * 2006-03-28 2011-11-24 花王株式会社 口腔用組成物
JP5633998B2 (ja) * 2006-09-27 2014-12-03 三栄源エフ・エフ・アイ株式会社 歯の再石灰化促進剤およびこれを含む口腔または経口用組成物
JP5354865B2 (ja) * 2007-03-30 2013-11-27 太陽化学株式会社 リン酸カルシウム溶解抑制剤
JP5553396B2 (ja) * 2007-04-10 2014-07-16 株式会社サンギ 再石灰化促進剤及び口腔用組成物
JP5196127B2 (ja) * 2007-12-19 2013-05-15 ライオン株式会社 口腔用組成物
JP5656368B2 (ja) * 2009-05-29 2015-01-21 花王株式会社 歯磨剤
BR112012019844A2 (pt) 2010-02-12 2017-12-05 Theocorp Holding Co Llc metodos e composições para melhorar a resistência mecânica dos dentes

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5626838A (en) * 1995-03-13 1997-05-06 The Procter & Gamble Company Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx
US5919426A (en) * 1995-12-27 1999-07-06 Biomedical Development Corporation Products of apatite-forming-systems
US20050054682A1 (en) * 1996-01-04 2005-03-10 Phillips Jeffrey O. Pharmaceutical compositions comprising substituted benzimidazoles and methods of using same
US20050152852A1 (en) * 2002-05-27 2005-07-14 Morinaga & Co., Ltd. Use of antibacterial component extracted from cacao mass for inhibiting the growth of periodontal bacteria
US20060189566A1 (en) * 2003-02-26 2006-08-24 Miho Komatsu Muscle building agent and preventive or remedy for muscle weakening
US20080214675A1 (en) * 2004-08-27 2008-09-04 Symrise Gmbh & Co. Kg Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste
US20090087501A1 (en) * 2007-10-01 2009-04-02 Colgate-Palmolive Company Oral Compositions Containing Botanical Extracts

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105189736A (zh) * 2013-03-15 2015-12-23 斯欧考普控股公司 适用于提高胎儿体重增加并增强骨特性的可可碱组合物
CN105611911A (zh) * 2013-10-09 2016-05-25 罗盖特公司 多元醇在牙釉质再矿化中的用途
CN107427700A (zh) * 2014-12-24 2017-12-01 墨尔本大学 矿化氟化物组合物
CN110917210A (zh) * 2019-12-27 2020-03-27 安徽医科大学 一种牙齿矿化漂白双功能糊剂、制备方法及应用

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AU2011215617B2 (en) 2016-01-28
EP2533786B1 (en) 2016-12-28
JP2013519688A (ja) 2013-05-30
RU2591084C2 (ru) 2016-07-10
SG183277A1 (en) 2012-09-27
SG10201500795WA (en) 2015-04-29
ES2617758T3 (es) 2017-06-19
KR20120123534A (ko) 2012-11-08
AU2011215617A1 (en) 2012-09-13
EP2533786A4 (en) 2013-06-12
ZA201206742B (en) 2013-05-29
US20130129641A1 (en) 2013-05-23
EP2533786A2 (en) 2012-12-19
US9610235B2 (en) 2017-04-04
CA2789595C (en) 2017-11-28
WO2011100671A2 (en) 2011-08-18
CA2789595A1 (en) 2011-08-18
BR112012019844A2 (pt) 2017-12-05
CN106668064A (zh) 2017-05-17
JP6114036B2 (ja) 2017-04-12
NZ601989A (en) 2014-11-28
MX2012009313A (es) 2012-11-06
WO2011100671A3 (en) 2011-12-22
IL221403A0 (en) 2012-10-31
RU2012133316A (ru) 2014-03-20

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