SG183277A1 - Methods and compositions to improve mechanical resistance of teeth - Google Patents
Methods and compositions to improve mechanical resistance of teeth Download PDFInfo
- Publication number
- SG183277A1 SG183277A1 SG2012059564A SG2012059564A SG183277A1 SG 183277 A1 SG183277 A1 SG 183277A1 SG 2012059564 A SG2012059564 A SG 2012059564A SG 2012059564 A SG2012059564 A SG 2012059564A SG 183277 A1 SG183277 A1 SG 183277A1
- Authority
- SG
- Singapore
- Prior art keywords
- composition
- phosphate
- combinations
- hardness
- theobromine
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 115
- 238000000034 method Methods 0.000 title claims abstract description 68
- 208000002925 dental caries Diseases 0.000 claims abstract description 32
- YAPQBXQYLJRXSA-UHFFFAOYSA-N theobromine Chemical compound CN1C(=O)NC(=O)C2=C1N=CN2C YAPQBXQYLJRXSA-UHFFFAOYSA-N 0.000 claims description 221
- 229960004559 theobromine Drugs 0.000 claims description 108
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims description 74
- 239000011775 sodium fluoride Substances 0.000 claims description 37
- 235000013024 sodium fluoride Nutrition 0.000 claims description 37
- 239000000551 dentifrice Substances 0.000 claims description 36
- 238000007373 indentation Methods 0.000 claims description 27
- XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 claims description 25
- 229960004711 sodium monofluorophosphate Drugs 0.000 claims description 25
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 22
- 239000011575 calcium Substances 0.000 claims description 22
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 22
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 22
- 239000001506 calcium phosphate Substances 0.000 claims description 21
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 20
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 18
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- 229910052791 calcium Inorganic materials 0.000 claims description 17
- 150000003839 salts Chemical class 0.000 claims description 17
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 16
- 229910019142 PO4 Inorganic materials 0.000 claims description 16
- 229960005069 calcium Drugs 0.000 claims description 16
- 239000010452 phosphate Substances 0.000 claims description 16
- -1 polymorphs Chemical compound 0.000 claims description 16
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 15
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- 239000002562 thickening agent Substances 0.000 claims description 12
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- HEBKCHPVOIAQTA-QWWZWVQMSA-N D-arabinitol Chemical compound OC[C@@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-QWWZWVQMSA-N 0.000 claims description 6
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- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims description 6
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- 229960004494 calcium gluconate Drugs 0.000 claims description 6
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 claims description 6
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- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 claims description 6
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Dental Preparations (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30377410P | 2010-02-12 | 2010-02-12 | |
| PCT/US2011/024734 WO2011100671A2 (en) | 2010-02-12 | 2011-02-14 | Methods and compositions to improve mechanical resistance of teeth |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG183277A1 true SG183277A1 (en) | 2012-09-27 |
Family
ID=44368492
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2012059564A SG183277A1 (en) | 2010-02-12 | 2011-02-14 | Methods and compositions to improve mechanical resistance of teeth |
| SG10201500795WA SG10201500795WA (en) | 2010-02-12 | 2011-02-14 | Compositions comprising theobromine to improve mechanical strength of teeth |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201500795WA SG10201500795WA (en) | 2010-02-12 | 2011-02-14 | Compositions comprising theobromine to improve mechanical strength of teeth |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9610235B2 (enExample) |
| EP (1) | EP2533786B1 (enExample) |
| JP (1) | JP6114036B2 (enExample) |
| KR (1) | KR20120123534A (enExample) |
| CN (2) | CN102821768A (enExample) |
| AU (1) | AU2011215617B2 (enExample) |
| BR (1) | BR112012019844A2 (enExample) |
| CA (1) | CA2789595C (enExample) |
| ES (1) | ES2617758T3 (enExample) |
| IL (1) | IL221403A0 (enExample) |
| MX (1) | MX2012009313A (enExample) |
| NZ (1) | NZ601989A (enExample) |
| RU (1) | RU2591084C2 (enExample) |
| SG (2) | SG183277A1 (enExample) |
| WO (1) | WO2011100671A2 (enExample) |
| ZA (1) | ZA201206742B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2705826T3 (pl) | 2006-02-09 | 2020-11-02 | The University Of Melbourne | Kompozycja fluorku i sposoby mineralizacji zębów |
| BR112012019844A2 (pt) | 2010-02-12 | 2017-12-05 | Theocorp Holding Co Llc | metodos e composições para melhorar a resistência mecânica dos dentes |
| US9962325B2 (en) | 2012-06-20 | 2018-05-08 | Theocorp Holding Co., Llc | Compositions containing theobromine and their use in treating tooth hypersensitivity |
| CN105189736A (zh) * | 2013-03-15 | 2015-12-23 | 斯欧考普控股公司 | 适用于提高胎儿体重增加并增强骨特性的可可碱组合物 |
| WO2015010166A1 (en) | 2013-07-23 | 2015-01-29 | The University Of Melbourne | Compositions and methods for dental mineralization |
| FR3011466A1 (fr) * | 2013-10-09 | 2015-04-10 | Roquette Freres | Utilisation d'un polyol dans la remineralisation de l'email |
| WO2015095932A1 (en) | 2013-12-24 | 2015-07-02 | The University Of Melbourne | Stabilized stannous compositions |
| KR102187824B1 (ko) * | 2014-03-26 | 2020-12-07 | 주식회사 엘지생활건강 | 치면 부착용 겔 조성물 및 이를 포함하는 키트 |
| US20180008518A1 (en) * | 2014-12-24 | 2018-01-11 | The University Of Melbourne | Mineralization fluoride compositions |
| CA3055091A1 (en) | 2017-03-14 | 2018-09-20 | The University Of Melbourne | Treatment for gingivitis |
| BR112019018871A2 (pt) | 2017-03-14 | 2020-04-14 | Univ Melbourne | complexos para tratar sensibilidade |
| CN110917210B (zh) * | 2019-12-27 | 2022-04-19 | 安徽医科大学 | 一种牙齿矿化漂白双功能糊剂、制备方法及应用 |
| CN112094699B (zh) * | 2020-09-27 | 2023-03-28 | 广西壮族自治区林业科学研究院 | 一种樟树纯露的提取方法 |
| DE102021111387A1 (de) | 2021-05-03 | 2022-11-03 | Dr. Kurt Wolff Gmbh & Co. Kg | Oralgel-Zusammensetzung und ihre Verwendung |
| DE102021111354A1 (de) * | 2021-05-03 | 2022-11-03 | Dr. Kurt Wolff Gmbh & Co. Kg | Mundpflegemittel |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4007431A1 (de) * | 1990-03-09 | 1991-09-12 | Henkel Kgaa | Den zahnschmelz schuetzende mund- und zahnpflegemittel |
| US5626838A (en) * | 1995-03-13 | 1997-05-06 | The Procter & Gamble Company | Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx |
| US5571502A (en) * | 1995-08-08 | 1996-11-05 | Enamelon Research | Stable single-part compositions and the use thereof for remineralization of lesions in teeth |
| US6183711B1 (en) * | 1995-12-27 | 2001-02-06 | Tetsuo Nakamoto | Apatite-forming-systems: methods and products |
| US20050054682A1 (en) * | 1996-01-04 | 2005-03-10 | Phillips Jeffrey O. | Pharmaceutical compositions comprising substituted benzimidazoles and methods of using same |
| JP3719874B2 (ja) * | 1998-04-24 | 2005-11-24 | サンスター株式会社 | 口腔用組成物 |
| US6685920B2 (en) * | 1999-11-12 | 2004-02-03 | The Procter & Gamble Company | Method of protecting teeth against erosion |
| KR20030032484A (ko) * | 2001-10-18 | 2003-04-26 | 롯데제과주식회사 | 발암 억제효능을 갖는 데오브로민 |
| EP1508335B1 (en) * | 2002-05-27 | 2011-09-28 | Morinaga & Co. Ltd. | Compositions comprising a cocoa fraction for use in the treatment of periodontitis caused by bacteria belonging to genus porphyromonas, prevotella, fusobacterium or actinobacillus |
| US20050152852A1 (en) * | 2002-05-27 | 2005-07-14 | Morinaga & Co., Ltd. | Use of antibacterial component extracted from cacao mass for inhibiting the growth of periodontal bacteria |
| US6953817B2 (en) * | 2002-08-05 | 2005-10-11 | Colgate-Palmolive Company | Dual component dentinal desensitizing dentifrice |
| US20040034042A1 (en) * | 2002-08-14 | 2004-02-19 | Masao Tsuji | Preservative composition |
| WO2004075905A1 (ja) | 2003-02-26 | 2004-09-10 | Kyowa Hakko Kogyo Co., Ltd. | 筋肉増強剤および筋肉減衰の予防または治療剤 |
| DE102004041496A1 (de) | 2004-08-27 | 2006-03-02 | Symrise Gmbh & Co. Kg | Hydroxybenzoesäureamide und deren Verwendung zur Maskierung von bitterem Geschmack |
| JP4820320B2 (ja) * | 2006-03-28 | 2011-11-24 | 花王株式会社 | 口腔用組成物 |
| JP5633998B2 (ja) * | 2006-09-27 | 2014-12-03 | 三栄源エフ・エフ・アイ株式会社 | 歯の再石灰化促進剤およびこれを含む口腔または経口用組成物 |
| JP5354865B2 (ja) * | 2007-03-30 | 2013-11-27 | 太陽化学株式会社 | リン酸カルシウム溶解抑制剤 |
| JP5553396B2 (ja) * | 2007-04-10 | 2014-07-16 | 株式会社サンギ | 再石灰化促進剤及び口腔用組成物 |
| EP2517716A1 (en) * | 2007-10-01 | 2012-10-31 | Colgate-Palmolive Company | Oral compositions containing botanical extracts |
| JP5196127B2 (ja) * | 2007-12-19 | 2013-05-15 | ライオン株式会社 | 口腔用組成物 |
| JP5656368B2 (ja) * | 2009-05-29 | 2015-01-21 | 花王株式会社 | 歯磨剤 |
| BR112012019844A2 (pt) | 2010-02-12 | 2017-12-05 | Theocorp Holding Co Llc | metodos e composições para melhorar a resistência mecânica dos dentes |
-
2011
- 2011-02-14 BR BR112012019844A patent/BR112012019844A2/pt not_active IP Right Cessation
- 2011-02-14 KR KR1020127023088A patent/KR20120123534A/ko not_active Withdrawn
- 2011-02-14 US US13/642,125 patent/US9610235B2/en active Active
- 2011-02-14 CA CA2789595A patent/CA2789595C/en active Active
- 2011-02-14 RU RU2012133316/15A patent/RU2591084C2/ru not_active Application Discontinuation
- 2011-02-14 CN CN2011800104594A patent/CN102821768A/zh active Pending
- 2011-02-14 AU AU2011215617A patent/AU2011215617B2/en not_active Ceased
- 2011-02-14 JP JP2012553073A patent/JP6114036B2/ja active Active
- 2011-02-14 SG SG2012059564A patent/SG183277A1/en unknown
- 2011-02-14 CN CN201710170152.XA patent/CN106668064A/zh active Pending
- 2011-02-14 NZ NZ601989A patent/NZ601989A/en not_active IP Right Cessation
- 2011-02-14 EP EP11742948.0A patent/EP2533786B1/en active Active
- 2011-02-14 ES ES11742948.0T patent/ES2617758T3/es active Active
- 2011-02-14 SG SG10201500795WA patent/SG10201500795WA/en unknown
- 2011-02-14 MX MX2012009313A patent/MX2012009313A/es active IP Right Grant
- 2011-02-14 WO PCT/US2011/024734 patent/WO2011100671A2/en not_active Ceased
-
2012
- 2012-08-09 IL IL221403A patent/IL221403A0/en unknown
- 2012-09-10 ZA ZA2012/06742A patent/ZA201206742B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011215617B2 (en) | 2016-01-28 |
| EP2533786B1 (en) | 2016-12-28 |
| JP2013519688A (ja) | 2013-05-30 |
| RU2591084C2 (ru) | 2016-07-10 |
| SG10201500795WA (en) | 2015-04-29 |
| ES2617758T3 (es) | 2017-06-19 |
| KR20120123534A (ko) | 2012-11-08 |
| AU2011215617A1 (en) | 2012-09-13 |
| EP2533786A4 (en) | 2013-06-12 |
| ZA201206742B (en) | 2013-05-29 |
| US20130129641A1 (en) | 2013-05-23 |
| EP2533786A2 (en) | 2012-12-19 |
| US9610235B2 (en) | 2017-04-04 |
| CA2789595C (en) | 2017-11-28 |
| WO2011100671A2 (en) | 2011-08-18 |
| CN102821768A (zh) | 2012-12-12 |
| CA2789595A1 (en) | 2011-08-18 |
| BR112012019844A2 (pt) | 2017-12-05 |
| CN106668064A (zh) | 2017-05-17 |
| JP6114036B2 (ja) | 2017-04-12 |
| NZ601989A (en) | 2014-11-28 |
| MX2012009313A (es) | 2012-11-06 |
| WO2011100671A3 (en) | 2011-12-22 |
| IL221403A0 (en) | 2012-10-31 |
| RU2012133316A (ru) | 2014-03-20 |
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