MX2011005365A - Antimicrobianos novedosos. - Google Patents

Antimicrobianos novedosos.

Info

Publication number
MX2011005365A
MX2011005365A MX2011005365A MX2011005365A MX2011005365A MX 2011005365 A MX2011005365 A MX 2011005365A MX 2011005365 A MX2011005365 A MX 2011005365A MX 2011005365 A MX2011005365 A MX 2011005365A MX 2011005365 A MX2011005365 A MX 2011005365A
Authority
MX
Mexico
Prior art keywords
heteroaryl
aryl
heterocyclyl
substituted
ring
Prior art date
Application number
MX2011005365A
Other languages
English (en)
Spanish (es)
Inventor
Sudhir Kumar Sharma
Rajesh Jain
Jagattaran Das
Sitaram Kumar Magadi
Sanjay Trehan
Sandeep Kanwar
Original Assignee
Panacea Biotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd
Publication of MX2011005365A publication Critical patent/MX2011005365A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX2011005365A 2008-11-20 2009-11-18 Antimicrobianos novedosos. MX2011005365A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2623DE2008 2008-11-20
PCT/IN2009/000658 WO2010058423A2 (en) 2008-11-20 2009-11-18 Novel antimicrobials

Publications (1)

Publication Number Publication Date
MX2011005365A true MX2011005365A (es) 2011-06-24

Family

ID=42198604

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011005365A MX2011005365A (es) 2008-11-20 2009-11-18 Antimicrobianos novedosos.

Country Status (12)

Country Link
US (1) US8841306B2 (enExample)
EP (1) EP2367820B1 (enExample)
JP (1) JP5662940B2 (enExample)
KR (1) KR20110092309A (enExample)
CN (1) CN102224151A (enExample)
AR (1) AR074387A1 (enExample)
AU (1) AU2009318783A1 (enExample)
CA (1) CA2743971A1 (enExample)
MX (1) MX2011005365A (enExample)
RU (1) RU2522582C2 (enExample)
WO (1) WO2010058423A2 (enExample)
ZA (1) ZA201103978B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012049161A1 (en) * 2010-10-13 2012-04-19 Glaxo Group Limited 3 -amino- pyrazole derivatives useful against tuberculosis
PT106651A (pt) * 2012-11-20 2014-05-20 Tecnimede Sociedade Tecnico Medicinal S A Quinolil hidrazonas para o tratamento de tuberculose e doenças relacionadas
CN103450173B (zh) * 2013-09-07 2015-06-03 吉首大学 吡咯酮-苯基-噁唑烷酮型化合物及其制法和用途
WO2017156519A1 (en) 2016-03-11 2017-09-14 The Board Of Trustees Of The University Of Illinois Small-molecules active against gram-negative bacteria
US11274106B2 (en) 2017-06-23 2022-03-15 The Board Of Trustees Of The University Of Illinois Topoisomerase inhibitors with antibacterial and anticancer activity
CN115427050B (zh) * 2020-02-07 2025-02-14 南佛罗里达大学 对tau蛋白病中的β-抑制蛋白寡聚化的抑制

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU667198B2 (en) 1991-11-01 1996-03-14 Pharmacia & Upjohn Company Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5646244A (en) 1993-09-06 1997-07-08 Fujisawa Pharmaceutical Co., Ltd. Cyclodepsipeptide compound
AU702752B2 (en) 1995-05-11 1999-03-04 Pharmacia & Upjohn Company Spirocyclic and bicyclic diazinyl and carbazinyl oxazolidinones
CA2228647A1 (en) 1995-09-01 1997-03-13 Pharmacia & Upjohn Company Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
KR20010052615A (ko) * 1998-06-05 2001-06-25 다비드 에 질레스 옥사졸리디논 유도체, 이것의 제조 방법 및 이것을함유하는 약학 조성물
JP2000204084A (ja) 1998-11-11 2000-07-25 Hokuriku Seiyaku Co Ltd チオカルバミド酸誘導体
AU1379900A (en) 1998-11-17 2000-06-05 Bayer Aktiengesellschaft Novel substituted phenyloxazolidone derivatives
JP2003501351A (ja) 1999-05-27 2003-01-14 ファルマシア・アンド・アップジョン・カンパニー 抗菌剤としての二環系オキサゾリジノン
US6608081B2 (en) 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
BR0111280A (pt) 2000-06-05 2003-06-10 Dong A Pharm Co Ltd Novos derivados de oxazolidinona e um processo para a preparação dos mesmos
JP2004501965A (ja) 2000-06-30 2004-01-22 ファルマシア・アンド・アップジョン・カンパニー 細菌感染を治療するための組成物および方法
DOP2002000333A (es) 2001-02-14 2002-09-30 Warner Lambert Co Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz
WO2002081470A1 (en) 2001-04-07 2002-10-17 Astrazeneca Ab Oxazolidinones containing a sulfonimid group as antibiotics
GB0108793D0 (en) 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
EP1406889A2 (en) 2001-07-09 2004-04-14 Pharmacia Italia S.p.A. Interaction inhibitors of tcf-4 with beta-catenin
EP1409464A4 (en) 2001-07-16 2005-11-02 Ranbaxy Lab Ltd OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
BR0310074A (pt) 2002-05-15 2005-03-08 Ranbaxy Lab Ltd Formas polimórficas de derivados de fenil oxazolidinona
WO2003097640A1 (en) 2002-05-22 2003-11-27 Orchid Chemicals & Pharmaceuticals Ltd. Oxazolidinone derivatives as antibacterial agents
WO2004009587A1 (en) 2002-07-22 2004-01-29 Orchid Chemicals & Pharmaceuticals Ltd Oxazolidinone derivatives as antibacterial agents
CN1668308A (zh) 2002-07-29 2005-09-14 兰贝克赛实验室有限公司 作为抗菌剂的噁唑烷酮衍生物
EP1578734A1 (en) * 2002-08-22 2005-09-28 Orchid Chemicals and Pharmaceuticals Ltd Novel antibacterial agents
US6875784B2 (en) 2002-10-09 2005-04-05 Pharmacia & Upjohn Company Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives
WO2004045616A1 (en) * 2002-11-21 2004-06-03 Pharmacia & Upjohn Company Llc N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinone-5-carboxamide derivates and related compounds as antibacterial agents
GB0229518D0 (en) 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
GB0229526D0 (en) 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
CN1237056C (zh) * 2002-12-25 2006-01-18 中国科学院上海药物研究所 噁唑烷酮类化合物、其制备方法和用途
AU2003215861A1 (en) * 2003-04-07 2004-11-01 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
CA2521685A1 (en) 2003-04-09 2004-10-21 Pharmacia & Upjohn Company Llc Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues
WO2004113329A1 (en) 2003-06-20 2004-12-29 Orchid Chemicals And Pharmaceuticals Ltd. Oxazole derivatives as antibacterial agents
WO2005003087A2 (en) 2003-07-01 2005-01-13 Orchid Chemicals And Pharmaceuticals Ltd. Oxazole derivatives as antibacterial agents
US20060247286A1 (en) 2003-07-02 2006-11-02 Milton Hammond Oxazolidinone antibiotics and derivatives thereof
JP2007521284A (ja) 2003-07-02 2007-08-02 メルク アンド カンパニー インコーポレーテッド オキサゾリジノン系抗生物質及びその誘導体
US20050118624A1 (en) * 2003-10-03 2005-06-02 Cumbre Inc. Fluorescent probes for ribosomes and method of use
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
WO2005082900A2 (en) 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
WO2005082897A1 (en) 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone antibacterial agents
MXPA06013540A (es) 2004-05-25 2007-01-26 Astrazeneca Ab Derivados de 3-(4-(2 -dihidroisoxasol -3-ilpiridin-5-il) fenil)-5- triazol-1- ilmetiloxazolidin -2-ona como inhibidores de mao para el tratamiento de infecciones bacterianas.
US20080064689A1 (en) 2004-05-25 2008-03-13 Astrazeneca Ab 3-[4-(6-Pyridin-3-Yl)-3-Phenyl] -5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents
WO2006035283A1 (en) 2004-09-27 2006-04-06 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
WO2006043121A1 (en) 2004-10-20 2006-04-27 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
KR101284573B1 (ko) 2005-04-12 2013-07-11 바이코어 파마 아베 신규한 트리시클릭 안지오텐신 ⅱ 아고니스트
EP1745784A1 (en) 2005-06-27 2007-01-24 Ferrer Internacional, S.A. Oxazolidinone derivatives and use thereof as antibiotics
CA2614105A1 (en) 2005-07-06 2007-01-11 Pharmacia & Upjohn Company Llc Oxazolidinone carboxamides containing azetidine and cyclobutane as antibacterial agents
KR20070038236A (ko) 2005-10-05 2007-04-10 일동제약주식회사 신규 옥사졸리디논 포름 아미드 유도체 및 그 제조방법
JP2009523764A (ja) * 2006-01-19 2009-06-25 ラボラトリオス・サルバト・ソシエダッド・アノニマ 抗菌活性を有するジカルボニル化合物
DK1987025T3 (da) 2006-02-14 2009-12-07 Pfizer Prod Inc Benzoxazinon og benzoxazepinonoxazolidinoner som antibakterielle midler
CN100406455C (zh) 2006-02-20 2008-07-30 中国科学院上海药物研究所 含三氮唑基的噁唑烷酮类化合物及其制备方法和用途
EP2181994B1 (en) 2006-03-31 2014-05-28 Research Foundation Itsuu Laboratory Antimicrobial compounds
WO2009001192A2 (en) * 2007-06-22 2008-12-31 Orchid Research Laboratories Limited Novel compounds and their use
CN101434584A (zh) * 2007-11-15 2009-05-20 中山大学 具有抗菌活性的手性噁唑烷酮类化合物

Also Published As

Publication number Publication date
ZA201103978B (en) 2012-09-26
WO2010058423A9 (en) 2011-04-28
RU2522582C2 (ru) 2014-07-20
JP5662940B2 (ja) 2015-02-04
AU2009318783A1 (en) 2011-06-23
JP2012509313A (ja) 2012-04-19
RU2011124795A (ru) 2012-12-27
AR074387A1 (es) 2011-01-12
WO2010058423A3 (en) 2010-12-09
EP2367820A4 (en) 2012-06-20
US8841306B2 (en) 2014-09-23
EP2367820A2 (en) 2011-09-28
CN102224151A (zh) 2011-10-19
CA2743971A1 (en) 2010-05-27
WO2010058423A2 (en) 2010-05-27
US20110245258A1 (en) 2011-10-06
EP2367820B1 (en) 2016-09-21
KR20110092309A (ko) 2011-08-17

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Legal Events

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FA Abandonment or withdrawal