MX2011004082A - Peptidos de dominio citoplasmico muc-1 como inhibidores del cancer. - Google Patents

Peptidos de dominio citoplasmico muc-1 como inhibidores del cancer.

Info

Publication number
MX2011004082A
MX2011004082A MX2011004082A MX2011004082A MX2011004082A MX 2011004082 A MX2011004082 A MX 2011004082A MX 2011004082 A MX2011004082 A MX 2011004082A MX 2011004082 A MX2011004082 A MX 2011004082A MX 2011004082 A MX2011004082 A MX 2011004082A
Authority
MX
Mexico
Prior art keywords
muc1
peptide
consecutive residues
cell
cqc
Prior art date
Application number
MX2011004082A
Other languages
English (en)
Spanish (es)
Inventor
Donald W Kufe
Surender Kharbanda
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Publication of MX2011004082A publication Critical patent/MX2011004082A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4727—Mucins, e.g. human intestinal mucin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1735—Mucins, e.g. human intestinal mucin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MX2011004082A 2008-10-17 2009-10-16 Peptidos de dominio citoplasmico muc-1 como inhibidores del cancer. MX2011004082A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10638008P 2008-10-17 2008-10-17
US17710909P 2009-05-11 2009-05-11
PCT/US2009/061051 WO2010045586A2 (en) 2008-10-17 2009-10-16 Muc-1 cytoplasmic domain peptides as inhibitors of cancer

Publications (1)

Publication Number Publication Date
MX2011004082A true MX2011004082A (es) 2011-10-14

Family

ID=42046194

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011004082A MX2011004082A (es) 2008-10-17 2009-10-16 Peptidos de dominio citoplasmico muc-1 como inhibidores del cancer.

Country Status (19)

Country Link
US (3) US8524669B2 (enExample)
EP (2) EP2352508B1 (enExample)
JP (2) JP5657549B2 (enExample)
KR (1) KR101689408B1 (enExample)
CN (1) CN102245632B (enExample)
AU (1) AU2009305550B2 (enExample)
BR (1) BRPI0920360A2 (enExample)
CA (1) CA2741065C (enExample)
DE (1) DE09740811T9 (enExample)
DK (1) DK2352508T3 (enExample)
ES (1) ES2395028T3 (enExample)
IL (1) IL212383A (enExample)
MX (1) MX2011004082A (enExample)
NZ (1) NZ592537A (enExample)
PL (1) PL2352508T3 (enExample)
PT (1) PT2352508E (enExample)
RU (1) RU2539832C2 (enExample)
WO (1) WO2010045586A2 (enExample)
ZA (1) ZA201103150B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011004082A (es) 2008-10-17 2011-10-14 Dana Farber Cancer Inst Inc Peptidos de dominio citoplasmico muc-1 como inhibidores del cancer.
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US20130231385A1 (en) 2010-05-28 2013-09-05 The Board Of Regents Of The University Of Texas Systems Oligo-benzamide compounds and their use
US8907054B2 (en) * 2011-08-08 2014-12-09 Marquette University Dpy-30 binding peptides
CN109010809A (zh) * 2011-08-17 2018-12-18 全球免疫股份有限公司 酵母-muc1免疫治疗组合物及其用途
EP2753345B1 (en) * 2011-09-06 2016-07-13 Agency For Science, Technology And Research Polypeptide vaccine
US8754124B2 (en) 2011-11-23 2014-06-17 Board Of Regents, The University Of Texas System Oligo-benzamide compounds and their use in treating cancers
US8835493B2 (en) 2011-11-23 2014-09-16 Board Of Regents, The University Of Texas System Oligo-benzamide compounds for use in treating cancers
US9044421B2 (en) 2012-03-28 2015-06-02 Genus Oncology, Llc Treating MUC1-expressing cancers with combination therapies
US9789156B2 (en) 2013-03-11 2017-10-17 Dana-Farber Cancer Institute, Inc. Combination anti-human epidermal growth factor receptor 2 (anti-HER2) cancer therapy using mucin 1 (MUC1) peptides and hemotherapeutics
US9572855B2 (en) 2013-03-11 2017-02-21 Dana-Farber Cancer Institute, Inc. Combination anti-estrogen receptor cancer therapy using MUC1 peptides and chemotherapeutics
CN106132992B (zh) 2014-01-29 2020-08-07 达娜-法勃肿瘤研究所公司 针对muc1-c/胞外结构域(muc1-c/ecd)的抗体
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WO2025217515A2 (en) 2024-04-12 2025-10-16 Dana-Farber Cancer Institute, Inc. Identification of muc1-c as a target for the treatment of squamous cell carcinomas
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Also Published As

Publication number Publication date
WO2010045586A3 (en) 2011-01-13
US20120172312A1 (en) 2012-07-05
ES2395028T1 (es) 2013-02-07
IL212383A (en) 2017-10-31
EP2352508A2 (en) 2011-08-10
DK2352508T3 (da) 2014-04-28
HK1160795A1 (en) 2012-08-17
DE09740811T1 (de) 2012-03-22
EP2727601A1 (en) 2014-05-07
WO2010045586A8 (en) 2011-08-04
AU2009305550A1 (en) 2010-04-22
US8957185B2 (en) 2015-02-17
US8524669B2 (en) 2013-09-03
NZ592537A (en) 2012-07-27
EP2727601B1 (en) 2018-06-13
BRPI0920360A2 (pt) 2021-03-02
EP2352508B1 (en) 2014-04-02
IL212383A0 (en) 2011-06-30
JP2015096513A (ja) 2015-05-21
PT2352508E (pt) 2014-05-26
ES2395028T3 (es) 2014-05-30
US20150152152A1 (en) 2015-06-04
WO2010045586A2 (en) 2010-04-22
US20100125055A1 (en) 2010-05-20
RU2011119606A (ru) 2012-11-27
US9546201B2 (en) 2017-01-17
CA2741065A1 (en) 2010-04-22
PL2352508T3 (pl) 2014-09-30
KR20110093801A (ko) 2011-08-18
DE09740811T9 (de) 2013-10-31
KR101689408B1 (ko) 2016-12-23
ZA201103150B (en) 2014-12-23
JP6030622B2 (ja) 2016-11-24
CN102245632A (zh) 2011-11-16
CA2741065C (en) 2017-04-25
JP2012505922A (ja) 2012-03-08
JP5657549B2 (ja) 2015-01-21
RU2539832C2 (ru) 2015-01-27
AU2009305550B2 (en) 2014-06-12
CN102245632B (zh) 2018-10-12

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