RU2539832C2 - Пептиды цитоплазматического домена белка muc-1 в качестве ингибиторов раковых заболеваний - Google Patents

Пептиды цитоплазматического домена белка muc-1 в качестве ингибиторов раковых заболеваний Download PDF

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RU2539832C2
RU2539832C2 RU2011119606/10A RU2011119606A RU2539832C2 RU 2539832 C2 RU2539832 C2 RU 2539832C2 RU 2011119606/10 A RU2011119606/10 A RU 2011119606/10A RU 2011119606 A RU2011119606 A RU 2011119606A RU 2539832 C2 RU2539832 C2 RU 2539832C2
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muc1
peptide
cell
residues
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Дональд В. КУФЕ
Сарендер КХАРБАНДА
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Дана-Фарбер Кэнсер Инститьют, Инк.
ДЖЕНУС ОНКОЛОДЖИ, ЭлЭлСи
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4727Mucins, e.g. human intestinal mucin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1735Mucins, e.g. human intestinal mucin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
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  • Biophysics (AREA)
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  • Engineering & Computer Science (AREA)
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  • Epidemiology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2011119606/10A 2008-10-17 2009-10-16 Пептиды цитоплазматического домена белка muc-1 в качестве ингибиторов раковых заболеваний RU2539832C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10638008P 2008-10-17 2008-10-17
US61/106,380 2008-10-17
US17710909P 2009-05-11 2009-05-11
US61/177,109 2009-05-11
PCT/US2009/061051 WO2010045586A2 (en) 2008-10-17 2009-10-16 Muc-1 cytoplasmic domain peptides as inhibitors of cancer

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RU2011119606A RU2011119606A (ru) 2012-11-27
RU2539832C2 true RU2539832C2 (ru) 2015-01-27

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DK (1) DK2352508T3 (enExample)
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IL (1) IL212383A (enExample)
MX (1) MX2011004082A (enExample)
NZ (1) NZ592537A (enExample)
PL (1) PL2352508T3 (enExample)
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RU (1) RU2539832C2 (enExample)
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US8907054B2 (en) * 2011-08-08 2014-12-09 Marquette University Dpy-30 binding peptides
RU2017143985A (ru) * 2011-08-17 2019-02-14 Глоубиммьюн, Инк. Иммунотерапевтические композиции на основе дрожжей-muc1 и способы их применения
EP2753345B1 (en) * 2011-09-06 2016-07-13 Agency For Science, Technology And Research Polypeptide vaccine
WO2013078277A1 (en) * 2011-11-23 2013-05-30 The Board Of Regents Of The University Of Texas System Oligo-benzamide compounds and their use in treating cancers
WO2013078288A1 (en) * 2011-11-23 2013-05-30 The Board Of Regents Of The University Of Texas System Oligo-benzamide compounds for use in treating cancers
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WO2010045586A8 (en) 2011-08-04
CN102245632A (zh) 2011-11-16
JP2012505922A (ja) 2012-03-08
KR101689408B1 (ko) 2016-12-23
US8524669B2 (en) 2013-09-03
DE09740811T1 (de) 2012-03-22
EP2727601B1 (en) 2018-06-13
US20100125055A1 (en) 2010-05-20
CN102245632B (zh) 2018-10-12
DE09740811T9 (de) 2013-10-31
HK1160795A1 (en) 2012-08-17
AU2009305550A1 (en) 2010-04-22
EP2727601A1 (en) 2014-05-07
US20150152152A1 (en) 2015-06-04
WO2010045586A3 (en) 2011-01-13
JP6030622B2 (ja) 2016-11-24
MX2011004082A (es) 2011-10-14
EP2352508A2 (en) 2011-08-10
ES2395028T3 (es) 2014-05-30
JP2015096513A (ja) 2015-05-21
US9546201B2 (en) 2017-01-17
ES2395028T1 (es) 2013-02-07
IL212383A (en) 2017-10-31
NZ592537A (en) 2012-07-27
DK2352508T3 (da) 2014-04-28
IL212383A0 (en) 2011-06-30
US8957185B2 (en) 2015-02-17
PL2352508T3 (pl) 2014-09-30
JP5657549B2 (ja) 2015-01-21
KR20110093801A (ko) 2011-08-18
CA2741065A1 (en) 2010-04-22
RU2011119606A (ru) 2012-11-27
PT2352508E (pt) 2014-05-26
EP2352508B1 (en) 2014-04-02
BRPI0920360A2 (pt) 2021-03-02
WO2010045586A2 (en) 2010-04-22
ZA201103150B (en) 2014-12-23
US20120172312A1 (en) 2012-07-05
CA2741065C (en) 2017-04-25
AU2009305550B2 (en) 2014-06-12

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