MX2009009624A - Droxidopa y composicion farmaceutica de la misma para el tratamiento de la fibromialgia. - Google Patents

Droxidopa y composicion farmaceutica de la misma para el tratamiento de la fibromialgia.

Info

Publication number
MX2009009624A
MX2009009624A MX2009009624A MX2009009624A MX2009009624A MX 2009009624 A MX2009009624 A MX 2009009624A MX 2009009624 A MX2009009624 A MX 2009009624A MX 2009009624 A MX2009009624 A MX 2009009624A MX 2009009624 A MX2009009624 A MX 2009009624A
Authority
MX
Mexico
Prior art keywords
fibromyalgia
treatment
droxidopa
methods
pharmaceutical composition
Prior art date
Application number
MX2009009624A
Other languages
English (en)
Inventor
Michael J Roberts
Simon Pedder
Original Assignee
Chelsea Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chelsea Therapeutics Inc filed Critical Chelsea Therapeutics Inc
Publication of MX2009009624A publication Critical patent/MX2009009624A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Nutrition Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención proporciona métodos para tratar fibromialgia u otras enfermedades o padecimientos que ocasionan dolor generalizado y/o fatiga. En particular, la invención proporciona composiciones farmacéuticas que comprenden droxidopa sola, o en combinación con uno o más agentes activos adicionales, que pueden usarse en los métodos inventivos. Los métodos de tratamiento pueden comprender tratar, prevenir, reducir, o eliminar una diversidad de síntomas reconocidos como indicativos de fibromialgia, tales como dolor crónico, alodinia, hiperalgesia, fatiga, alteración del sueño, y depresión.
MX2009009624A 2007-03-09 2008-03-07 Droxidopa y composicion farmaceutica de la misma para el tratamiento de la fibromialgia. MX2009009624A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89403007P 2007-03-09 2007-03-09
PCT/US2008/056255 WO2008112562A1 (en) 2007-03-09 2008-03-07 Droxidopa and pharmaceutical composition thereof for the treatment of fibromyalgia

Publications (1)

Publication Number Publication Date
MX2009009624A true MX2009009624A (es) 2009-12-11

Family

ID=39666215

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009009624A MX2009009624A (es) 2007-03-09 2008-03-07 Droxidopa y composicion farmaceutica de la misma para el tratamiento de la fibromialgia.

Country Status (12)

Country Link
US (2) US8008285B2 (es)
EP (2) EP2134335B1 (es)
JP (1) JP2010520885A (es)
KR (1) KR20100014392A (es)
CN (1) CN101657193A (es)
AU (1) AU2008226541B2 (es)
BR (1) BRPI0808647A2 (es)
CA (1) CA2680272A1 (es)
ES (2) ES2500053T3 (es)
MX (1) MX2009009624A (es)
NZ (1) NZ579368A (es)
WO (1) WO2008112562A1 (es)

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Also Published As

Publication number Publication date
JP2010520885A (ja) 2010-06-17
EP2134335A1 (en) 2009-12-23
AU2008226541B2 (en) 2013-05-09
CA2680272A1 (en) 2008-09-18
EP2468271A1 (en) 2012-06-27
KR20100014392A (ko) 2010-02-10
CN101657193A (zh) 2010-02-24
ES2500053T3 (es) 2014-09-29
EP2468271B1 (en) 2014-07-16
US20080221170A1 (en) 2008-09-11
EP2134335B1 (en) 2014-04-23
US8008285B2 (en) 2011-08-30
NZ579368A (en) 2012-03-30
BRPI0808647A2 (pt) 2014-08-12
WO2008112562A1 (en) 2008-09-18
ES2480966T3 (es) 2014-07-29
AU2008226541A1 (en) 2008-09-18
US20110259786A1 (en) 2011-10-27

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