MX2009005114A - Uso de los profarmacos gabapentina y pregabalina para tratar el tinnitus. - Google Patents
Uso de los profarmacos gabapentina y pregabalina para tratar el tinnitus.Info
- Publication number
- MX2009005114A MX2009005114A MX2009005114A MX2009005114A MX2009005114A MX 2009005114 A MX2009005114 A MX 2009005114A MX 2009005114 A MX2009005114 A MX 2009005114A MX 2009005114 A MX2009005114 A MX 2009005114A MX 2009005114 A MX2009005114 A MX 2009005114A
- Authority
- MX
- Mexico
- Prior art keywords
- gabapentin
- pregabalin
- prodrugs
- treating tinnitus
- pregabalin prodrugs
- Prior art date
Links
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title abstract 6
- 208000009205 Tinnitus Diseases 0.000 title abstract 3
- 229960002870 gabapentin Drugs 0.000 title abstract 3
- 229960001233 pregabalin Drugs 0.000 title abstract 3
- AYXYPKUFHZROOJ-ZETCQYMHSA-N pregabalin Chemical compound CC(C)C[C@H](CN)CC(O)=O AYXYPKUFHZROOJ-ZETCQYMHSA-N 0.000 title abstract 3
- 239000000651 prodrug Substances 0.000 title abstract 3
- 229940002612 prodrug Drugs 0.000 title abstract 3
- 231100000886 tinnitus Toxicity 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se describen métodos para utilizar profármacos de gabapentina y pregabalina y composiciones farmacéuticas de los mismos para tratar tinnitus, y composiciones farmacéuticas de profármacos de gabapentina o pregabalina útiles para tratar tinnitus.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85928306P | 2006-11-14 | 2006-11-14 | |
PCT/US2007/023944 WO2008060572A1 (en) | 2006-11-14 | 2007-11-13 | Use of gabapentin and pregabalin prodrugs for treating tinnitus |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009005114A true MX2009005114A (es) | 2009-07-16 |
Family
ID=39111439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009005114A MX2009005114A (es) | 2006-11-14 | 2007-11-13 | Uso de los profarmacos gabapentina y pregabalina para tratar el tinnitus. |
Country Status (9)
Country | Link |
---|---|
US (1) | US20080188562A1 (es) |
EP (1) | EP2086530A1 (es) |
CN (1) | CN101616664A (es) |
AU (1) | AU2007319851A1 (es) |
BR (1) | BRPI0718754A2 (es) |
CA (1) | CA2669246A1 (es) |
EA (1) | EA200970483A1 (es) |
MX (1) | MX2009005114A (es) |
WO (1) | WO2008060572A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8048917B2 (en) * | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US7186855B2 (en) * | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US7025745B2 (en) * | 2002-10-07 | 2006-04-11 | Advanced Cardiovascular Systems, Inc. | Method of making a catheter balloon using a tapered mandrel |
CA2537837A1 (en) * | 2003-09-11 | 2005-03-24 | Xenoport, Inc. | Treating and/or preventing urinary incontinence using prodrugs of gaba analogs |
JP4308263B2 (ja) * | 2003-10-14 | 2009-08-05 | ゼノポート,インコーポレイティド | γ−アミノ酪酸アナログの結晶形 |
WO2006050514A1 (en) | 2004-11-04 | 2006-05-11 | Xenoport, Inc. | Gabapentin prodrug sustained release oral dosage forms |
MX2007012688A (es) * | 2005-04-15 | 2008-03-14 | Synta Pharmaceuticals Corp | Terapia de combinacion para el cancer con compuestos de bis(tiohidrazida) amida. |
CN101652133A (zh) * | 2006-12-08 | 2010-02-17 | 克塞诺波特公司 | Gaba类似物的前药用于治疗疾病的用途 |
US20080206332A1 (en) * | 2007-01-11 | 2008-08-28 | Kidney David J | Sustained release oral dosage forms of a prodrug of r-baclofen and methods of treatment |
NZ594648A (en) * | 2009-03-03 | 2013-12-20 | Xenoport Inc | Sustained release oral dosage forms of an r-baclofen prodrug |
US20110130454A1 (en) * | 2009-11-24 | 2011-06-02 | Xenoport, Inc. | Prodrugs of gamma-amino acid, alpha-2-delta ligands, pharmaceutical compositions and uses thereof |
EP2530072A1 (en) | 2011-06-03 | 2012-12-05 | Lacer, S.A. | New compounds, synthesis and use thereof in the treatment of pain |
CN105777586A (zh) * | 2016-04-14 | 2016-07-20 | 安徽省逸欣铭医药科技有限公司 | S(+)氨己烯酸酯衍生物及其制备方法和用途 |
WO2022256545A1 (en) * | 2021-06-04 | 2022-12-08 | Nevakar Injectables Inc. | Injectable pregabalin formulations |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6818787B2 (en) * | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US7186855B2 (en) * | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
IL162028A0 (en) * | 2002-01-31 | 2005-11-20 | Warner Lambert Co | Alpha 2 delta ligands to treat tinnitus |
AU2003222033A1 (en) * | 2002-03-20 | 2003-10-08 | Xenoport | Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof |
US7662987B2 (en) * | 2003-07-15 | 2010-02-16 | Xenoport, Inc. | Methods for synthesis of acyloxyalkyl compounds |
CA2540247C (en) * | 2003-09-25 | 2011-01-25 | Warner-Lambert Company Llc | Prodrugs of amino acids with affinity for the .alpha.2.delta.-protein |
-
2007
- 2007-11-13 AU AU2007319851A patent/AU2007319851A1/en not_active Abandoned
- 2007-11-13 MX MX2009005114A patent/MX2009005114A/es not_active Application Discontinuation
- 2007-11-13 EA EA200970483A patent/EA200970483A1/ru unknown
- 2007-11-13 EP EP07853121A patent/EP2086530A1/en not_active Withdrawn
- 2007-11-13 WO PCT/US2007/023944 patent/WO2008060572A1/en active Application Filing
- 2007-11-13 CN CN200780049819A patent/CN101616664A/zh active Pending
- 2007-11-13 BR BRPI0718754-8A patent/BRPI0718754A2/pt not_active Application Discontinuation
- 2007-11-13 CA CA002669246A patent/CA2669246A1/en not_active Abandoned
- 2007-11-13 US US11/939,517 patent/US20080188562A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20080188562A1 (en) | 2008-08-07 |
EA200970483A1 (ru) | 2009-12-30 |
WO2008060572A1 (en) | 2008-05-22 |
BRPI0718754A2 (pt) | 2013-12-03 |
AU2007319851A1 (en) | 2008-05-22 |
EP2086530A1 (en) | 2009-08-12 |
CA2669246A1 (en) | 2008-05-22 |
CN101616664A (zh) | 2009-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |