EA200970483A1 - Применение пролекарств габапентина и прегабалина для лечения шума в ушах - Google Patents

Применение пролекарств габапентина и прегабалина для лечения шума в ушах

Info

Publication number
EA200970483A1
EA200970483A1 EA200970483A EA200970483A EA200970483A1 EA 200970483 A1 EA200970483 A1 EA 200970483A1 EA 200970483 A EA200970483 A EA 200970483A EA 200970483 A EA200970483 A EA 200970483A EA 200970483 A1 EA200970483 A1 EA 200970483A1
Authority
EA
Eurasian Patent Office
Prior art keywords
gabapentin
pregabalin
ears
drugs
application
Prior art date
Application number
EA200970483A
Other languages
English (en)
Inventor
Ноа Зеранге
Original Assignee
Ксенопорт, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ксенопорт, Инк. filed Critical Ксенопорт, Инк.
Publication of EA200970483A1 publication Critical patent/EA200970483A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Раскрыты способы использования пролекарств габапентина или прегабалина и их фармацевтических композиций для лечения шума в ушах и фармацевтические композиции пролекарств габапентина или прегабалина, пригодные для лечения шума в ушах.
EA200970483A 2006-11-14 2007-11-13 Применение пролекарств габапентина и прегабалина для лечения шума в ушах EA200970483A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85928306P 2006-11-14 2006-11-14
PCT/US2007/023944 WO2008060572A1 (en) 2006-11-14 2007-11-13 Use of gabapentin and pregabalin prodrugs for treating tinnitus

Publications (1)

Publication Number Publication Date
EA200970483A1 true EA200970483A1 (ru) 2009-12-30

Family

ID=39111439

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200970483A EA200970483A1 (ru) 2006-11-14 2007-11-13 Применение пролекарств габапентина и прегабалина для лечения шума в ушах

Country Status (9)

Country Link
US (1) US20080188562A1 (ru)
EP (1) EP2086530A1 (ru)
CN (1) CN101616664A (ru)
AU (1) AU2007319851A1 (ru)
BR (1) BRPI0718754A2 (ru)
CA (1) CA2669246A1 (ru)
EA (1) EA200970483A1 (ru)
MX (1) MX2009005114A (ru)
WO (1) WO2008060572A1 (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) * 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7025745B2 (en) * 2002-10-07 2006-04-11 Advanced Cardiovascular Systems, Inc. Method of making a catheter balloon using a tapered mandrel
JP2007505149A (ja) * 2003-09-11 2007-03-08 ゼノポート，インコーポレイティド ギャバ類似体のプロドラッグを用いる尿失禁の治療および／あるいは予防
KR101096480B1 (ko) * 2003-10-14 2011-12-20 제노포트 인코포레이티드 감마-아미노부티르산 유사체의 결정질 형태
US8795725B2 (en) 2004-11-04 2014-08-05 Xenoport, Inc. GABA analog prodrug sustained release oral dosage forms
AU2006236378B2 (en) * 2005-04-15 2010-12-02 Synta Pharmaceuticals Corp. Combination cancer therapy with bis(thiohydrazide) amide compounds
JP2010512314A (ja) * 2006-12-08 2010-04-22 ゼノポート，インコーポレーテッド 疾患を治療するためのｇａｂａアナログのプロドラッグの使用
ES2365574T3 (es) * 2007-01-11 2011-10-07 Xenoport, Inc. Formas de dosificación oral para liberación continua de un profármaco de r-baclofeno y procedimientos de tratamiento.
CA2753057C (en) * 2009-03-03 2018-09-11 Xenoport, Inc. Sustained release oral dosage forms of an r-baclofen prodrug
US20110130454A1 (en) * 2009-11-24 2011-06-02 Xenoport, Inc. Prodrugs of gamma-amino acid, alpha-2-delta ligands, pharmaceutical compositions and uses thereof
EP2530072A1 (en) 2011-06-03 2012-12-05 Lacer, S.A. New compounds, synthesis and use thereof in the treatment of pain
CN105777586A (zh) * 2016-04-14 2016-07-20 安徽省逸欣铭医药科技有限公司 S（+）氨己烯酸酯衍生物及其制备方法和用途
WO2022256545A1 (en) * 2021-06-04 2022-12-08 Nevakar Injectables Inc. Injectable pregabalin formulations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7186855B2 (en) * 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6818787B2 (en) * 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
CN1625393A (zh) * 2002-01-31 2005-06-08 沃纳-兰伯特公司 治疗耳鸣的α2δ配体
US7026351B2 (en) * 2002-03-20 2006-04-11 Xenoport, Inc. Cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs, compositions and uses thereof
US7662987B2 (en) * 2003-07-15 2010-02-16 Xenoport, Inc. Methods for synthesis of acyloxyalkyl compounds
EP1670750A1 (en) * 2003-09-25 2006-06-21 Warner-Lambert Company LLC Prodrugs of amino acids with affinity for the alpha2delta- protein

Also Published As

Publication number Publication date
MX2009005114A (es) 2009-07-16
US20080188562A1 (en) 2008-08-07
WO2008060572A1 (en) 2008-05-22
CA2669246A1 (en) 2008-05-22
EP2086530A1 (en) 2009-08-12
BRPI0718754A2 (pt) 2013-12-03
CN101616664A (zh) 2009-12-30
AU2007319851A1 (en) 2008-05-22

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