MX2007000770A - Induccion de apoptosis en celulas tumorales que expresan el receptor tipo toll. - Google Patents
Induccion de apoptosis en celulas tumorales que expresan el receptor tipo toll.Info
- Publication number
- MX2007000770A MX2007000770A MX2007000770A MX2007000770A MX2007000770A MX 2007000770 A MX2007000770 A MX 2007000770A MX 2007000770 A MX2007000770 A MX 2007000770A MX 2007000770 A MX2007000770 A MX 2007000770A MX 2007000770 A MX2007000770 A MX 2007000770A
- Authority
- MX
- Mexico
- Prior art keywords
- cells
- poly
- tlr
- ligand
- cancer
- Prior art date
Links
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0331—Animal model for proliferative diseases
Landscapes
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- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
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- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US58961604P | 2004-07-20 | 2004-07-20 | |
| PCT/US2005/025602 WO2006014653A1 (en) | 2004-07-20 | 2005-07-19 | Induction of apoptosis in toll-like receptor expressing tumor cells |
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| MX2007000770A true MX2007000770A (es) | 2007-03-26 |
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| MX2007000770A MX2007000770A (es) | 2004-07-20 | 2005-07-19 | Induccion de apoptosis en celulas tumorales que expresan el receptor tipo toll. |
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| NO (1) | NO20070945L (enExample) |
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| EP2258712A3 (en) * | 2002-03-15 | 2011-05-04 | Multicell Immunotherapeutics, Inc. | Compositions and Methods to Initiate or Enhance Antibody and Major-histocompatibility Class I or Class II-restricted T Cell Responses by Using Immunomodulatory, Non-coding RNA Motifs |
| AU2004225480A1 (en) * | 2003-03-26 | 2004-10-14 | Multicell Immunotherapeutics, Inc. | Selected RNA motifs to include cell death and/or apoptosis |
| WO2006054129A1 (en) * | 2004-11-19 | 2006-05-26 | Institut Gustave Roussy | Improved treatment of cancer by double-stranded rna |
| US20120189643A1 (en) * | 2004-11-30 | 2012-07-26 | Carton Jill M | Toll Like Receptor 3 Antagonists, Methods and Uses |
| EP2522352B1 (en) | 2006-03-02 | 2017-01-11 | Agency for Science, Technology and Research | Methods for stem cells modulation |
| US8957035B2 (en) | 2006-05-15 | 2015-02-17 | University Of Kentucky Research Foundation | Toll like receptor (TLR) stimulation for ocular angiogenesis and macular degeneration |
| EP1881080A1 (en) * | 2006-07-18 | 2008-01-23 | Institut Gustave Roussy | Toll like receptor 4 dysfunction and the biological applications thereof |
| US20080124366A1 (en) * | 2006-08-06 | 2008-05-29 | Ohlfest John R | Methods and Compositions for Treating Tumors |
| JP5115921B2 (ja) * | 2007-02-28 | 2013-01-09 | 株式会社ペルセウスプロテオミクス | 腎癌の診断薬および治療薬 |
| AU2008242540A1 (en) * | 2007-04-24 | 2008-10-30 | John Wayne Cancer Institute | Functional toll-like receptors (TLR) on melanocytes and melanoma cells and uses thereof |
| SG185942A1 (en) * | 2007-11-02 | 2012-12-28 | Agency Science Tech & Res | Methods and compounds for preventing and treating a tumour |
| JP2011505011A (ja) * | 2007-11-28 | 2011-02-17 | スマート チューブ，インコーポレイテッド | 生体試料の採取、刺激、安定化及び分析のためのデバイス、システム及び方法 |
| AU2009215795A1 (en) | 2008-02-21 | 2009-08-27 | University Of Kentucky Research Foundation | Ultra-small RNAs as toll-like receptor-3 antagonists |
| CA2722589A1 (en) | 2008-04-25 | 2009-10-29 | Innate Pharma | Improved tlr3 agonist compositions |
| WO2010020590A1 (en) * | 2008-08-20 | 2010-02-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the response to anti-cancer treatment with an agonist of tlr7 or an agonist of tlr8 |
| GB0820698D0 (en) * | 2008-11-12 | 2008-12-17 | Ludwig Inst Cancer Res | Uses of immunomodulators |
| WO2010068680A1 (en) | 2008-12-10 | 2010-06-17 | Mount Sinai School Of Medicine Of New York University | Thelper cell type 17 lineage-specific adjuvants, compositions and methods |
| US20120301463A1 (en) | 2009-09-30 | 2012-11-29 | President And Fellows Of Harvard College | Methods for Modulation of Autophagy Through the Modulation of Autophagy-Enhancing Gene Products |
| WO2011072871A1 (en) * | 2009-12-18 | 2011-06-23 | Bavarian Nordic A/S | Production of ifn-lambda by conventional dendritic cells and uses thereof |
| KR101250419B1 (ko) * | 2010-12-16 | 2013-04-05 | 강원대학교산학협력단 | Ｔｌｒ 작동제를 포함하는 유방암 방사선 치료 보조제 |
| RU2014103159A (ru) * | 2011-07-22 | 2015-08-27 | Павел КАЛИНСКИЙ | Опухолесективная модуляция хемокинов |
| CN102652802A (zh) * | 2012-04-18 | 2012-09-05 | 南京中医药大学 | 癌毒方在制备调控肝癌细胞TLRs／NF-κB信号转导药物中的应用 |
| WO2014022287A1 (en) * | 2012-07-29 | 2014-02-06 | The Regents Of The University Of Colorado, A Body Corporate | Antagonists of the toll-like receptor 1/2 complex |
| WO2015127002A1 (en) * | 2014-02-19 | 2015-08-27 | The Johns Hopkins University | Compositions and methods for promoting skin regeneration and hair growth |
| US10434064B2 (en) | 2014-06-04 | 2019-10-08 | Exicure, Inc. | Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications |
| CN105796594A (zh) * | 2016-03-28 | 2016-07-27 | 南京大学 | 一种组合物在制备治疗肿瘤药物中的应用及该组合物的使用方法 |
| CN106191238B (zh) * | 2016-07-08 | 2020-01-10 | 中国医学科学院基础医学研究所 | Tlr3预测肿瘤转移、评估预后和选择防治方案的应用 |
| WO2018039629A2 (en) | 2016-08-25 | 2018-03-01 | Northwestern University | Micellar spherical nucleic acids from thermoresponsive, traceless templates |
| WO2018209270A1 (en) | 2017-05-11 | 2018-11-15 | Northwestern University | Adoptive cell therapy using spherical nucleic acids (snas) |
| CN108295060A (zh) * | 2018-04-08 | 2018-07-20 | 王长国 | 一种tlr7激动剂在增强cik细胞对肿瘤细胞杀伤力方面的应用 |
| WO2020232226A1 (en) | 2019-05-16 | 2020-11-19 | The Johns Hopkins University | Compositions and methods for skin rejuvenation |
| CN111117966A (zh) * | 2020-03-02 | 2020-05-08 | 南通大学 | 一种利用乳酸的体外细胞培养方法 |
| CN111579538B (zh) * | 2020-04-22 | 2022-12-30 | 山东第一医科大学(山东省医学科学院) | 一种利用凋亡试剂盒检测循环肿瘤细胞的方法 |
| CA3221194A1 (en) * | 2021-05-24 | 2022-12-01 | Cha Vaccine Research Institute Co., Ltd | Immuno-oncology therapeutic composition using adjuvant including lipopeptides and poly (i:c) |
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| JP3040121B2 (ja) * | 1988-01-12 | 2000-05-08 | ジェネンテク，インコーポレイテッド | 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法 |
| CN1040504A (zh) * | 1988-06-22 | 1990-03-21 | Hem研究公司 | 用双链核糖核酸调节淋巴激活素抗性细胞状态 |
| RU2136278C1 (ru) * | 1998-04-07 | 1999-09-10 | Государственный научный центр вирусологии и биотехнологии "Вектор" | Противоопухолевое средство |
| US20040006242A1 (en) * | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
| AU2002360243A1 (en) * | 2001-07-26 | 2003-05-06 | Tanox, Inc. | Agents that activate or inhibit toll-like receptor 9 |
| TW200303759A (en) * | 2001-11-27 | 2003-09-16 | Schering Corp | Methods for treating cancer |
| AU2003295649A1 (en) * | 2002-11-22 | 2004-06-18 | Nuvelo,Inc. | Methods of therapy and diagnosis |
| JP3810731B2 (ja) * | 2002-11-29 | 2006-08-16 | 独立行政法人科学技術振興機構 | 哺乳動物のＴｏｌｌ様受容体３に結合する新規アダプタータンパク質およびその遺伝子 |
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- 2005-07-19 MX MX2007000770A patent/MX2007000770A/es unknown
- 2005-07-19 EP EP05774637A patent/EP1768699A1/en not_active Withdrawn
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2008
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2006014653A1 (en) | 2006-02-09 |
| NO20070945L (no) | 2007-02-19 |
| CN101018567A (zh) | 2007-08-15 |
| CN101018567B (zh) | 2011-07-27 |
| RU2401661C2 (ru) | 2010-10-20 |
| KR20070043795A (ko) | 2007-04-25 |
| AU2008249173A1 (en) | 2008-12-11 |
| US20060147456A1 (en) | 2006-07-06 |
| US20090285779A1 (en) | 2009-11-19 |
| AU2005269733B2 (en) | 2008-10-30 |
| AU2005269733A1 (en) | 2006-02-09 |
| JP2008507530A (ja) | 2008-03-13 |
| RU2007105987A (ru) | 2008-08-27 |
| EP1768699A1 (en) | 2007-04-04 |
| CA2574176A1 (en) | 2006-02-09 |
| ATE511859T1 (de) | 2011-06-15 |
| RU2401661C9 (ru) | 2011-01-27 |
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