MTP963B - A novel human physiologically active polypeptide - Google Patents

A novel human physiologically active polypeptide

Info

Publication number
MTP963B
MTP963B MT963A MTP963A MTP963B MT P963 B MTP963 B MT P963B MT 963 A MT963 A MT 963A MT P963 A MTP963 A MT P963A MT P963 B MTP963 B MT P963B
Authority
MT
Malta
Prior art keywords
physiologically active
active polypeptide
novel human
human physiologically
novel
Prior art date
Application number
MT963A
Other languages
English (en)
Inventor
Robert Bruce Wallace
Hirataha Itoh
Original Assignee
Asahi Chemical Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Ind filed Critical Asahi Chemical Ind
Publication of MTP963B publication Critical patent/MTP963B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/828—Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Image Analysis (AREA)
MT963A 1984-04-06 1985-04-04 A novel human physiologically active polypeptide MTP963B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/597,372 US4879226A (en) 1984-04-06 1984-04-06 Novel human physiologically active polypeptide

Publications (1)

Publication Number Publication Date
MTP963B true MTP963B (en) 1985-11-25

Family

ID=24391235

Family Applications (1)

Application Number Title Priority Date Filing Date
MT963A MTP963B (en) 1984-04-06 1985-04-04 A novel human physiologically active polypeptide

Country Status (39)

Country Link
US (1) US4879226A (fr)
EP (2) EP0158286A3 (fr)
JP (1) JPS60252496A (fr)
KR (1) KR920007399B1 (fr)
AR (1) AR240475A1 (fr)
AU (2) AU595480B2 (fr)
BE (1) BE902119A (fr)
BG (1) BG43355A3 (fr)
BR (1) BR8501624A (fr)
CA (1) CA1341348C (fr)
CH (2) CH672790A5 (fr)
DD (1) DD251785A5 (fr)
DK (1) DK151985A (fr)
EG (1) EG17965A (fr)
ES (1) ES8704976A1 (fr)
FI (1) FI86992C (fr)
FR (1) FR2564097B1 (fr)
GB (1) GB2158829B (fr)
GR (1) GR850836B (fr)
HK (1) HK102192A (fr)
HU (1) HUT37813A (fr)
IE (1) IE58833B1 (fr)
IL (1) IL74804A (fr)
IN (1) IN163653B (fr)
IT (1) IT1218469B (fr)
JO (1) JO1365B1 (fr)
LU (1) LU85835A1 (fr)
MA (1) MA20402A1 (fr)
MT (1) MTP963B (fr)
MY (1) MY101887A (fr)
NO (1) NO174473C (fr)
NZ (2) NZ231317A (fr)
OA (1) OA07983A (fr)
PL (1) PL156392B1 (fr)
PT (1) PT80239B (fr)
RO (1) RO93650B (fr)
SG (1) SG77892G (fr)
YU (1) YU57885A (fr)
ZA (1) ZA852563B (fr)

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JPH0695939B2 (ja) * 1983-12-02 1994-11-30 大日本製薬株式会社 ウサギ癌壊死因子をコ−ドするクロ−ン化ｄνａ
EP0155549B1 (fr) * 1984-03-06 1991-03-20 Dainippon Pharmaceutical Co., Ltd. ADN codant pour le facteur humain de nécrose de tumeur et le polypeptide du facteur humain de nécrose de tumeur
JP2584206B2 (ja) * 1984-08-17 1997-02-26 大日本製薬株式会社 ヒト癌壊死因子
US5288852A (en) * 1984-03-06 1994-02-22 Dainippon Pharmaceutical Co., Ltd. Human tumor necrosis factor polypeptides
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
JPS60228297A (ja) * 1984-04-24 1985-11-13 株式会社　東京タツノ 給油装置
US5672347A (en) * 1984-07-05 1997-09-30 Genentech, Inc. Tumor necrosis factor antagonists and their use
US6686455B1 (en) * 1984-07-05 2004-02-03 Genentech, Inc. Tumor necrosis factor
GR851626B (fr) * 1984-07-05 1985-11-26 Genentech Inc
JP2675294B2 (ja) * 1984-10-15 1997-11-12 カイロン コーポレイション ヒト腫瘍壊死因子
EP0200748B1 (fr) * 1984-10-15 1991-02-06 Cetus Corporation Facteur de necrose de tumeurs humaines
US4959314A (en) 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
JPS61124392A (ja) * 1984-11-22 1986-06-12 Asahi Chem Ind Co Ltd 遺伝子組換体の産生する生理活性物質の精製法
IL73883A (en) * 1984-12-20 1990-12-23 Yeda Res & Dev Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha
EP0368367A1 (fr) * 1984-12-21 1990-05-16 Biogen, Inc. Purification, production et utilisation de facteurs de nécrose de tumeur
JPS6248634A (ja) * 1985-07-23 1987-03-03 Mochida Pharmaceut Co Ltd 新規アミノ酸組成物、その製造方法及び該アミノ酸組成物を含有する医療組成物
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JPH0698004B2 (ja) * 1985-09-30 1994-12-07 サントリー株式会社 Ｔｎｆ発現用新規プラスミド
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US5998378A (en) * 1989-08-16 1999-12-07 Chiron Corporation Compositions for the inhibition of TNF hormone formation and uses thereof
US6586222B1 (en) 1989-08-16 2003-07-01 Chiron Corporation Recombinant PR-3 and compositions thereof
EP0897987B1 (fr) * 1989-10-24 2001-02-28 Chiron Corporation Sécretion de protéine humaine associée au peptide-signal de l' interferon gamma
US5653974A (en) * 1990-10-18 1997-08-05 Board Of Regents,The University Of Texas System Preparation and characterization of liposomal formulations of tumor necrosis factor
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KR970005042B1 (ko) * 1993-02-09 1997-04-11 한일합성섬유공업 주식회사 종양괴사인자-알파 뮤테인
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US6551623B1 (en) 1993-09-09 2003-04-22 Lorus Therapeutics Inc. Immunomodulating compositions from bile
EP0749494A1 (fr) 1994-03-07 1996-12-27 Chiron Corporation Compositions pour l'inhibition de la formation des facteurs de necrose tumorale (tnf) et leur utilisation
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US4359415A (en) * 1981-06-03 1982-11-16 University Of Tennessee Research Corporation Isolation of an antineoplastic protein fraction and an antineoplastic peptide fraction from human urine
FR2513124B1 (fr) * 1981-07-21 1989-11-17 Hayashibara Biochem Lab Production et applications du facteur de lyse des cellules-cibles
JPS5821621A (ja) * 1981-07-31 1983-02-08 Hayashibara Biochem Lab Inc ヒトツモア・ネクロシス・ファクタ−を含有する悪性腫瘍治療剤
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JPS59169492A (ja) * 1983-03-15 1984-09-25 Asahi Chem Ind Co Ltd ヒト融合細胞からの生理活性物質の産生方法
CA1265444A (fr) * 1983-06-27 1990-02-06 Lloyd J. Old Effet du facteur humain de necrose des tumeurs et de l'interferon humain sur des cellules cancereuses humaines et methodes utilisees
JPS6019719A (ja) * 1983-07-15 1985-01-31 Asahi Chem Ind Co Ltd 抗腫瘍活性を有する蛋白質
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Also Published As

Publication number Publication date
AU4088285A (en) 1985-10-10
RO93650A (fr) 1988-03-30
DD251785A5 (de) 1987-11-25
IT8520242A0 (it) 1985-04-05
GB8508864D0 (en) 1985-05-09
NZ211666A (en) 1990-01-29
FI851336A0 (fi) 1985-04-03
JO1365B1 (en) 1986-11-30
CH675423A5 (fr) 1990-09-28
SG77892G (en) 1992-10-02
BG43355A3 (en) 1988-05-16
PL252807A1 (en) 1986-02-25
GB2158829B (en) 1992-04-22
DK151985A (da) 1985-10-07
PT80239B (pt) 1988-02-17
ES8704976A1 (es) 1987-05-01
NO174473C (no) 1994-05-11
IE850863L (en) 1985-10-06
LU85835A1 (fr) 1985-12-16
HUT37813A (en) 1986-02-28
AU595480B2 (en) 1990-04-05
MY101887A (en) 1992-02-15
CH672790A5 (fr) 1989-12-29
JPS60252496A (ja) 1985-12-13
NZ231317A (en) 1991-01-29
NO851400L (no) 1985-10-07
YU57885A (en) 1989-02-28
RO93650B (ro) 1988-03-31
ZA852563B (en) 1986-05-28
PL156392B1 (pl) 1992-03-31
IL74804A (en) 1991-06-30
MA20402A1 (fr) 1985-12-31
OA07983A (en) 1987-01-31
IT1218469B (it) 1990-04-19
FR2564097B1 (fr) 1989-09-22
AU4016289A (en) 1989-12-07
DK151985D0 (da) 1985-04-03
PT80239A (en) 1985-05-01
IN163653B (fr) 1988-10-22
FR2564097A1 (fr) 1985-11-15
CA1341348C (fr) 2002-03-19
NO174473B (no) 1994-01-31
AR240475A1 (es) 1990-04-30
EP0158286A2 (fr) 1985-10-16
JPH025760B2 (fr) 1990-02-05
EP0354592A1 (fr) 1990-02-14
KR920007399B1 (ko) 1992-08-31
EG17965A (en) 1994-01-30
FI851336L (fi) 1985-10-07
IE58833B1 (en) 1993-11-17
IL74804A0 (en) 1985-07-31
BE902119A (fr) 1985-10-04
GR850836B (fr) 1985-06-26
US4879226A (en) 1989-11-07
KR850007273A (ko) 1985-12-02
FI86992C (fi) 1992-11-10
HK102192A (en) 1992-12-24
FI86992B (fi) 1992-07-31
GB2158829A (en) 1985-11-20
BR8501624A (pt) 1985-12-03
EP0158286A3 (fr) 1987-05-13
AU637054B2 (en) 1993-05-20
ES541920A0 (es) 1987-05-01

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