ME03347B - PARAZITICIDNE KOMPOZICIJE KOJE SADRŽE IZOKSAZOLINSKO AKTIVNO SREDSTVO, POSTUPCI l UPOTREBE POVEZANE SA NJIMA - Google Patents

PARAZITICIDNE KOMPOZICIJE KOJE SADRŽE IZOKSAZOLINSKO AKTIVNO SREDSTVO, POSTUPCI l UPOTREBE POVEZANE SA NJIMA

Info

Publication number
ME03347B
ME03347B MEP-2019-71A MEP201971A ME03347B ME 03347 B ME03347 B ME 03347B ME P201971 A MEP201971 A ME P201971A ME 03347 B ME03347 B ME 03347B
Authority
ME
Montenegro
Prior art keywords
antipest
isoxazoline
active agent
associated processes
compositions consisting
Prior art date
Application number
MEP-2019-71A
Other languages
German (de)
English (en)
French (fr)
Inventor
Mark D Soll
Joseph K Rosentel
James Pate
Natalya Shub
Monica Tejwani-Motwani
Carol Belansky
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47018471&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME03347(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merial Inc filed Critical Merial Inc
Publication of ME03347B publication Critical patent/ME03347B/me

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Insects & Arthropods (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MEP-2019-71A 2011-09-12 2019-09-12 PARAZITICIDNE KOMPOZICIJE KOJE SADRŽE IZOKSAZOLINSKO AKTIVNO SREDSTVO, POSTUPCI l UPOTREBE POVEZANE SA NJIMA ME03347B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161533308P 2011-09-12 2011-09-12
EP12772575.2A EP2755473B1 (en) 2011-09-12 2012-09-12 Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
PCT/US2012/054719 WO2013039948A1 (en) 2011-09-12 2012-09-12 Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof

Publications (1)

Publication Number Publication Date
ME03347B true ME03347B (me) 2019-10-20

Family

ID=47018471

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2019-71A ME03347B (me) 2011-09-12 2019-09-12 PARAZITICIDNE KOMPOZICIJE KOJE SADRŽE IZOKSAZOLINSKO AKTIVNO SREDSTVO, POSTUPCI l UPOTREBE POVEZANE SA NJIMA

Country Status (43)

Country Link
US (6) US9180121B2 (me)
EP (3) EP2755473B1 (me)
JP (3) JP6366102B2 (me)
KR (3) KR20200019793A (me)
CN (3) CN106474120B (me)
AP (1) AP2014007508A0 (me)
AR (3) AR087838A1 (me)
AU (5) AU2012308776B2 (me)
BR (2) BR112014005514B1 (me)
CA (1) CA2848317C (me)
CL (2) CL2014000601A1 (me)
CO (1) CO6910187A2 (me)
CR (2) CR20180572A (me)
CY (3) CY1121402T1 (me)
DK (2) DK3172964T3 (me)
EA (3) EA032162B1 (me)
ES (2) ES2715000T3 (me)
FR (1) FR21C1025I2 (me)
HR (2) HRP20190426T1 (me)
HU (3) HUE042360T2 (me)
IL (4) IL231358A (me)
IN (1) IN2014CN02128A (me)
LT (3) LT2755473T (me)
LU (1) LUC00211I2 (me)
MA (1) MA35431B1 (me)
ME (1) ME03347B (me)
MX (2) MX364978B (me)
MY (2) MY198581A (me)
NO (1) NO2021026I1 (me)
NZ (1) NZ725115A (me)
PE (1) PE20142292A1 (me)
PH (2) PH12018501647A1 (me)
PL (2) PL3172964T3 (me)
PT (2) PT3172964T (me)
RS (2) RS61048B1 (me)
SG (2) SG11201400558YA (me)
SI (2) SI2755473T1 (me)
SM (2) SMT201900149T1 (me)
TN (1) TN2014000105A1 (me)
TR (1) TR201903499T4 (me)
TW (2) TWI567064B (me)
WO (1) WO2013039948A1 (me)
ZA (1) ZA201401672B (me)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8658223B2 (en) 2011-07-13 2014-02-25 Clarke Mosquito Control Products, Inc. Insecticidal compositions and methods of using the same
HUE042360T2 (hu) * 2011-09-12 2019-06-28 Merial Inc Izoxazolin hatóanyagot tartalmazó parazitaellenes készítmények, ezek elõállítása és alkalmazása
AP2014007874A0 (en) * 2012-02-06 2014-08-31 Merial Ltd Parasiticidal oral veterinary compositions comprising systemetically- acting active agents, methods and uses thereof
CN108685894B (zh) 2012-04-04 2022-04-26 英特维特国际股份有限公司 软咀嚼药用产品
CN111803465B (zh) 2013-03-15 2023-05-09 阿根塔创新有限公司 可咀嚼配制物
WO2015066277A1 (en) * 2013-11-01 2015-05-07 Merial Limited Antiparisitic and pesticidal isoxazoline compounds
MX373872B (es) 2013-12-20 2020-03-26 Intervet Int Bv Composiciones de isoxazolina y uso de las mismas en la prevención o tratamiento de infestaciones parasitarias en animales.
ES2874054T3 (es) 2013-12-20 2021-11-04 Intervet Int Bv Uso de derivados de isoxazolina para el tratamiento o la prevención de la infestación con artrópodos en aves de corral
US10179722B2 (en) 2014-01-27 2019-01-15 Manitowoc Crane Companies, Llc Lift crane with improved movable counterweight
GB2523811A (en) * 2014-03-06 2015-09-09 Norbrook Lab Ltd Novel Isoxazolines and their uses
CN104095871A (zh) * 2014-07-10 2014-10-15 青岛蔚蓝生物股份有限公司 一种含盐酸林可霉素与硫酸大观霉素的兽用注射液
US20170232024A1 (en) 2014-08-04 2017-08-17 Jerry Tan Eye Surgery Pte Ltd Pharmaceutical compositions for demodex related blepharitis and eyelid crusting
DK4008329T3 (da) * 2014-12-22 2025-08-18 Intervet Int Bv Isoxazolinforbindelser til anvendelse i behandling af demodicose
GB2551451B (en) * 2015-02-03 2020-05-27 Bimeda Finance S A R L A formulation for treatment of blowfly strike
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
CA2981797C (en) * 2015-04-08 2023-11-21 Merial, Inc. Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof
BR112017027855B1 (pt) 2015-06-23 2022-11-16 Intervet International B.V. Composição farmacêutica, seu uso, água potável medicamentosa e método para sua preparação
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2017187725A1 (ja) * 2016-04-26 2017-11-02 オルガノ株式会社 水処理剤組成物および水処理方法
US20170333305A1 (en) * 2016-05-23 2017-11-23 Microban Products Company Topical skin product having retention property
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
JP2019535655A (ja) 2016-10-14 2019-12-12 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 殺虫性及び殺寄生虫性ビニルイソオキサゾリン化合物
US10980235B2 (en) 2017-02-13 2021-04-20 Clarke Mosquito Control Products, Inc. Insecticidal composition
CA3059114A1 (en) * 2017-04-05 2018-10-11 Boehringer Ingelheim Animal Health USA Inc. Crystalline forms of (s)-afoxolaner
US10420109B2 (en) * 2017-04-13 2019-09-17 Futurewei Technologies, Inc. System and method for providing explicit feedback in communications systems with multi-point connectivity
MX2020001724A (es) 2017-08-14 2020-07-29 Boehringer Ingelheim Animal Health Usa Inc Compuestos de pirazol-isoxazolina plaguicidas y parasiticidas.
CN119157876A (zh) * 2017-12-15 2024-12-20 塔苏斯制药有限公司 用于治疗睑炎的异恶唑啉驱虫剂制剂和方法
AR113997A1 (es) 2017-12-21 2020-07-08 Intervet Int Bv Composiciones antiparasitarias para unción dorsal continua
RU2676326C1 (ru) * 2017-12-26 2018-12-28 Федеральное государственное бюджетное научное учреждение "Прикаспийский зональный научно-исследовательский ветеринарный институт" Комплексная антибактериально-противогельминтозная композиция для лечения сельскохозяйственных животных и птиц
TWI812673B (zh) * 2018-02-12 2023-08-21 美商富曼西公司 用於防治無脊椎害蟲之萘異噁唑啉化合物
GB201809374D0 (en) * 2018-06-07 2018-07-25 Fish Vet Group Norge As Treatment for removing ectoparasites from fish
US12502377B2 (en) 2019-04-04 2025-12-23 Tarsus Pharmaceuticals, Inc. Method of eradicating ticks that attach to humans using lotilaner formulations
AU2020290958A1 (en) * 2019-06-14 2022-02-03 Piedmont Animal Health Inc. Long-acting topical formulation and method of use thereof
WO2021242481A1 (en) 2020-05-28 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
US12655138B2 (en) 2020-07-24 2026-06-16 Elanco Us Inc. Process for making an isoxazoline compound and intermediate thereof
AU2021335500A1 (en) 2020-09-04 2023-05-04 Elanco Us Inc. Palatable formulations
CA3203620A1 (en) * 2020-12-01 2022-06-09 Sumitomo Chemical Company, Limited Liquid pesticidal composition
EP4262789A1 (en) * 2020-12-21 2023-10-25 Boehringer Ingelheim Vetmedica GmbH Parasiticidal collar comprising isoxazoline compounds
CN112755049A (zh) * 2021-02-05 2021-05-07 哈密市动物疫病预防控制中心 用于提高犬绦虫病粪便检测灵敏度的泻剂配方及制备方法
CN114042065B (zh) * 2021-11-26 2024-03-15 长沙拜特生物科技研究所有限公司 一种复方甲苯咪唑透皮溶液剂及其制备方法
JP7857041B2 (ja) * 2022-03-01 2026-05-12 国立研究開発法人産業技術総合研究所 害虫の呼吸器形成機構を標的とする新規害虫防除方法
US20250195551A1 (en) * 2022-03-22 2025-06-19 L4 Bio Llc Liquid formulations of ivermectin compositions and use in gelatin dosage forms
CN117122571A (zh) * 2022-05-20 2023-11-28 天津瑞普生物技术股份有限公司 一种抗寄生虫感染的口服药物制剂及其制备方法和应用
US20240423959A1 (en) 2022-06-21 2024-12-26 Jjr&D, Llc Topical benzimidazole formulations and methods for use in treating inflammatory dermatoses
PE20242118A1 (es) * 2023-12-22 2024-10-28 Agrovet Market S A Composicion farmaceutica topica que comprende una asociacion de una isoxazolina con una lactona macrociclica y un derivado de pirazino-isoquinolina para el tratamiento de infestaciones parasitarias en animales menores
WO2025257633A1 (en) 2024-06-12 2025-12-18 Boehringer Ingelheim Vetmedica Gmbh Long-acting castor oil-containing injectable formulations and methods of use thereof
PL449854A1 (pl) * 2024-09-18 2026-03-23 Okoniewski Piotr Kompozycja farmaceutyczna, lecznicza woda pitna, ich zastosowanie i sposób wytwarzania leczniczej wody pitnej

Family Cites Families (117)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6426333B1 (en) 1996-09-19 2002-07-30 Merial Spot-on formulations for combating parasites
FR2753377B1 (fr) 1996-09-19 1999-09-24 Rhone Merieux Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides
NL160809C (nl) 1970-05-15 1979-12-17 Duphar Int Res Werkwijze ter bereiding van benzoylureumverbindingen, alsmede werkwijze ter bereiding van insekticide prepara- ten op basis van benzoylureumverbindingen.
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
JPS4914624A (me) 1972-06-08 1974-02-08
US3818047A (en) 1972-08-07 1974-06-18 C Henrick Substituted pyrones
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
CH604517A5 (me) 1976-08-19 1978-09-15 Ciba Geigy Ag
US4134973A (en) 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4144352A (en) 1977-12-19 1979-03-13 Merck & Co., Inc. Milbemycin compounds as anthelmintic agents
US4203976A (en) 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
JPS57139012A (en) 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4427663A (en) 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
JPS59199673A (ja) 1983-04-25 1984-11-12 Sumitomo Chem Co Ltd 含窒素複素環化合物、その製造法およびそれを有効成分とする有害生物防除剤
EP0179022B1 (de) 1984-10-18 1990-11-07 Ciba-Geigy Ag Benzoylphenylharnstoffe
ATE67493T1 (de) 1985-02-04 1991-10-15 Bayer Agrochem Kk Heterocyclische verbindungen.
DE3603799A1 (de) 1986-02-07 1987-08-13 Philips Patentverwaltung Stromspiegelschaltung
EP0237482A1 (de) 1986-03-06 1987-09-16 Ciba-Geigy Ag C(29)-Carbonyloxi-milbemycin-Derivate zur Bekämpfung von tier- und pflanzenparasitären Schädlingen
RU2024527C1 (ru) 1986-03-25 1994-12-15 Санкио Компани Лимитед Способ получения макролидных соединений
GB8613914D0 (en) 1986-06-07 1986-07-09 Coopers Animal Health Liquid formulations
DE3778768D1 (de) 1986-07-02 1992-06-11 Ciba Geigy Ag Pestizide.
US4855317A (en) 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
US4871719A (en) 1987-03-24 1989-10-03 Ciba-Geigy Corporation Composition for controlling parasites in productive livestock
US4874749A (en) 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
DE3888936T2 (de) 1987-11-03 1994-07-21 Beecham Group Plc Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung.
NZ232422A (en) 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
IE904606A1 (en) 1989-12-21 1991-07-03 Beecham Group Plc Novel products
NZ247278A (en) 1991-02-12 1995-03-28 Ancare Distributors Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier
WO1992022555A1 (en) 1991-06-17 1992-12-23 Beecham Group Plc Paraherquamide derivatives, precursor thereof, processes for their preparation, microorganism used and their use as antiparasitic agents
US5345377A (en) 1992-10-30 1994-09-06 Electric Power Research Institute, Inc. Harmonic controller for an active power line conditioner
GB9300883D0 (en) 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
US5399582A (en) 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents
DE4405898A1 (de) * 1994-02-18 1995-08-24 Schering Ag Transdermale therapeutische Systeme enthaltend Sexualsteroide
AUPM969994A0 (en) 1994-11-28 1994-12-22 Virbac S.A. Equine anthelmintic formulations
US6221894B1 (en) 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
US5962499A (en) 1995-03-20 1999-10-05 Merck & Co., Inc. Nodulisporic acid derivatives
MY113806A (en) 1995-07-21 2002-05-31 Upjohn Co Antiparasitic marcfortines and paraherquamides
FR2739255B1 (fr) 1995-09-29 1998-09-04 Rhone Merieux Composition antiparasitaire pour le traitement et la protection des animaux de compagnie
US6010710A (en) 1996-03-29 2000-01-04 Merial Direct pour-on skin solution for antiparasitic use in cattle and sheep
FR2752525B1 (fr) 1996-08-20 2000-05-05 Rhone Merieux Procede de lutte contre les myiases des cheptels bovins et ovins et compositions pour la mise en oeuvre de ce procede
IE80657B1 (en) 1996-03-29 1998-11-04 Merial Sas Insecticidal combination to control mammal fleas in particular fleas on cats and dogs
US5885607A (en) 1996-03-29 1999-03-23 Rhone Merieux N-phenylpyrazole-based anti-flea and anti-tick external device for cats and dogs
US6998131B2 (en) 1996-09-19 2006-02-14 Merial Limited Spot-on formulations for combating parasites
US6207647B1 (en) 1997-07-18 2001-03-27 Smithkline Beecham Corporation RatA
JPH1149669A (ja) * 1997-08-05 1999-02-23 Nitto Denko Corp 抗ウイルス剤含有テープ製剤
JP4237293B2 (ja) * 1998-05-19 2009-03-11 東光薬品工業株式会社 経皮吸収型貼付剤
US6174540B1 (en) 1998-09-14 2001-01-16 Merck & Co., Inc. Long acting injectable formulations containing hydrogenated caster oil
US6962691B1 (en) * 1999-05-20 2005-11-08 U & I Pharmaceuticals Ltd. Topical spray compositions
PE20011289A1 (es) 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
CA2311881C (en) 2000-06-16 2007-08-28 Gary O. Maupin Control of arthropods in rodents
US6399786B1 (en) 2000-07-14 2002-06-04 Merck & Co., Inc. Nonacyclic nodulisporic acid derivatives
TW200409760A (en) 2002-09-11 2004-06-16 Novartis Ag Organic compounds
US9265725B2 (en) * 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7262214B2 (en) 2003-02-26 2007-08-28 Merial Limited 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases
JP2004269368A (ja) * 2003-03-05 2004-09-30 Ogawa & Co Ltd 冷感剤組成物および該冷感剤組成物を含有する冷感化粧料
LT1610613T (lt) 2003-04-04 2017-03-27 Merial, Inc. Vietinio taikymo antihelmintinės veterinarinės kompozicijos
JP4405765B2 (ja) * 2003-08-04 2010-01-27 大阪化成株式会社 屋内性防ダニ剤
WO2005034952A2 (en) 2003-10-07 2005-04-21 The Feinstein Institute For Medical Research Isoxazole and isothiazole compounds useful in the treatment of inflammation
US7531186B2 (en) 2003-12-17 2009-05-12 Merial Limited Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz
BRPI0508140B1 (pt) * 2004-03-05 2015-03-17 Nissan Chemical Ind Ltd Composto benzamida substituída por isoxazolina da fórmula (1); da fórmula (2) substituído por 3,5-bis (aril substituído); da fórmula (4) substituída por alquinibenzeno ou um sal do mesmo; "pesticida, agroquímico, inseticida, parasiticida contendo como ingrediente ativo um ou mais composto benzamida substituída por isoxazolina e sal do mesmo"
US20050232876A1 (en) * 2004-04-19 2005-10-20 Robin Lynn Minga Skin care compositions
TWI350728B (en) * 2004-10-08 2011-10-21 Wyeth Corp Amitraz compositions
BRPI0612448A2 (pt) * 2005-05-09 2010-11-23 Foamix Ltd composição espumosa de sacarìdeo
US20060293260A1 (en) * 2005-05-24 2006-12-28 Wyeth Useful high load concentrate compositions for control of ecto-and endo-parasites
BRPI0617076B1 (pt) 2005-09-02 2021-07-06 Nissan Chemical Corporation Composto benzamida substituída por isoxazolina da fórmula (1) ou sal do mesmo; composto benzamida substituido por 4-hidroxiiminametila da fórmula (2) ou sal do mesmo; pesticida; agente agroquímico; parasiticida interno ou externo para mamíferos ou aves; inseticida ou acaricida
EP1965645A2 (en) 2005-12-14 2008-09-10 E.I. Du Pont De Nemours And Company Isoxazolines for controlling invertebrate pests
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 杜邦股份有限公司 控制無脊椎害蟲之異唑啉
US8058303B2 (en) 2006-03-08 2011-11-15 Nihon Nohyaku Co, Ltd Pharmaceutical composition for external use
EP1997813B1 (en) 2006-03-10 2010-05-05 Nissan Chemical Industries, Ltd. Substituted isoxazoline compound and pest control agent
WO2007123855A2 (en) 2006-04-20 2007-11-01 E. I. Du Pont De Nemours And Company Pyrazolines for controlling invertebrate pests
JP2008044880A (ja) 2006-08-15 2008-02-28 Bayer Cropscience Ag 殺虫性イソオキサゾリン類
SG172705A1 (en) * 2006-09-01 2011-07-28 Du Pont Local topical administration formulations containing indoxacarb
WO2008105614A1 (en) 2007-02-26 2008-09-04 Lg Chem, Ltd. Conductive laminated body and method for preparing the same
EP2151437A4 (en) 2007-03-07 2012-05-02 Nissan Chemical Ind Ltd ISOXAZOLINE SUBSTITUTED BENZAMIDE COMPOUND AND PEST CONTROL AGENT
JP5256753B2 (ja) 2007-03-29 2013-08-07 住友化学株式会社 イソオキサゾリン化合物とその有害生物防除用途
NZ580241A (en) 2007-04-10 2011-02-25 Bayer Cropscience Ag Insecticidal aryl isoxazoline derivatives
PT3088384T (pt) 2007-05-15 2019-03-22 Aventis Agriculture Compostos de ariloazol-2-il-cianoetilamino, método de fabrico e seu método de utilização
WO2008154528A2 (en) * 2007-06-13 2008-12-18 E. I. Du Pont De Nemours And Company Isoxazoline insecticides
US8263072B2 (en) 2007-06-22 2012-09-11 Genera Istrazivanja, d.o.o. ADAMTS4 as a blood biomarker and therapeutic target for chronic renal failure
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
DK2182945T3 (en) 2007-06-27 2015-11-16 Du Pont PROCEDURE TO COMBAT PESTS WITH ANIMALS
EP2172448A4 (en) 2007-06-29 2012-01-11 Nissan Chemical Ind Ltd SUBSTITUTED ISOXAZOLINE OR ENONOXINE COMPOUND AND PESTICIDES
CA2690111C (en) 2007-06-29 2011-11-15 Pfizer Inc. Anthelmintic combination
JP2010535231A (ja) 2007-07-31 2010-11-18 ワイス・エルエルシー 内部寄生虫駆除局所組成物
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TW200924647A (en) 2007-08-30 2009-06-16 Schering Plough Ltd Local topical administration formulations containing fipronil
JP5365806B2 (ja) 2007-09-10 2013-12-11 日産化学工業株式会社 置換イソキサゾリン化合物及び有害生物防除剤
US8367584B2 (en) 2007-10-03 2013-02-05 E.I. Du Pont De Nemours And Company Naphthalene isoxazoline compounds for control of invertebrate pests
CN102088857A (zh) 2008-07-09 2011-06-08 巴斯夫欧洲公司 包含异噁唑啉化合物的杀虫活性混合物ⅱ
BRPI0915665B1 (pt) 2008-07-09 2018-01-02 Basf Se Misturas pesticidas, métodos para proteger plantas do ataque ou infestação por insetos, acarídeos ou nematódeos, para controlar insetos, aracnídeos ou nematódeos, uso de uma mistura, e, composição pesticida ou parasiticida
DE102008034944B4 (de) * 2008-07-26 2017-03-16 Arivine Pharma Ag Mikroemulsion
JP2012501989A (ja) 2008-09-04 2012-01-26 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 殺虫化合物
KR101782311B1 (ko) 2008-10-21 2017-09-27 메리얼 인코포레이티드 티오아미드 화합물, 이의 제조 방법 및 사용 방법
ES2442342T3 (es) 2008-12-18 2014-02-11 Novartis Ag Derivados de las isoxazolinas y su uso como pesticida
CN102325759A (zh) 2008-12-23 2012-01-18 巴斯夫欧洲公司 用于防治动物害虫的取代脒化合物
US20110288089A1 (en) 2009-01-22 2011-11-24 Syngenta Crop Protection Llc Insecticidal compounds
EP2414353A1 (en) 2009-04-01 2012-02-08 Basf Se Isoxazoline compounds for combating invertebrate pests
CN101940790B (zh) * 2009-07-01 2012-07-25 润和生物医药科技(汕头)有限公司 一种新型促渗剂组合物及其在透皮给药系统中的应用
TWI487486B (zh) 2009-12-01 2015-06-11 Syngenta Participations Ag 以異唑啉衍生物為主之殺蟲化合物
PT3078664T (pt) 2009-12-17 2019-05-31 Boehringer Ingelheim Animal Health Usa Inc Composições antiparasitárias de di-hidroazoles
KR20120125332A (ko) 2010-02-01 2012-11-14 바스프 에스이 동물 해충을 퇴치하기 위한 치환된 케톤계 이속사졸린 화합물 및 유도체
MX2012009429A (es) 2010-02-25 2012-09-07 Syngenta Participations Ag Mezclas pesticidas que contienen derivados de isoxazolina y un agente biologico insecticida o nematicida.
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
EP2576523B1 (en) 2010-05-27 2016-01-13 E. I. du Pont de Nemours and Company Crystalline form of 4-[5 - [3 -chloro-5 -(trifluoromethyl)phenyl] -4,5 -dihydro-5 -(trifluoromethyl)-3 - isoxazolyl]-n-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1- naphthalenecarboxamide
US20130210623A1 (en) 2010-06-09 2013-08-15 Syngenta Crop Protection Llc Pesticidal mixtures including isoxazoline derivatives
BR112012031277A2 (pt) 2010-06-09 2016-09-27 Syngenta Participations Ag "misturas pesticidas compreendendo derivados de isoxazolina"
AR081843A1 (es) 2010-06-09 2012-10-24 Syngenta Participations Ag Mezclas pesticidas incluyendo derivados isoxazolina
DK178277B1 (da) * 2010-06-18 2015-10-26 Novartis Tiergesundheit Ag Diaryloxazolinforbindelser til bekæmpelse af fiskelus
WO2012007426A1 (en) 2010-07-13 2012-01-19 Basf Se Azoline substituted isoxazoline benzamide compounds for combating animal pests
ES2682303T3 (es) 2010-08-05 2018-09-19 Zoetis Services Llc Derivados de isoxazolina como agentes antiparasitarios
WO2012038851A1 (en) * 2010-09-24 2012-03-29 Pfizer Inc. Isoxazoline oximes as antiparasitic agents
CN103260620A (zh) 2010-12-27 2013-08-21 英特维特国际股份有限公司 包含三缩四乙二醇的外用局部异噁唑啉制剂
JP6002148B2 (ja) 2010-12-27 2016-10-05 インターベット インターナショナル ベー． フェー． 経表面局所イソオキサゾリン製剤
HUE042360T2 (hu) * 2011-09-12 2019-06-28 Merial Inc Izoxazolin hatóanyagot tartalmazó parazitaellenes készítmények, ezek elõállítása és alkalmazása
AP2014007874A0 (en) * 2012-02-06 2014-08-31 Merial Ltd Parasiticidal oral veterinary compositions comprising systemetically- acting active agents, methods and uses thereof

Also Published As

Publication number Publication date
KR20190038681A (ko) 2019-04-08
SMT202000632T1 (it) 2021-01-05
CY2021015I2 (el) 2021-10-15
CA2848317A1 (en) 2013-03-21
RS58417B1 (sr) 2019-04-30
CN106943399A (zh) 2017-07-14
EA201400340A1 (ru) 2014-08-29
TW201317219A (zh) 2013-05-01
MX2014002904A (es) 2014-05-07
HRP20190426T1 (hr) 2019-04-19
IL268295B (en) 2020-06-30
AU2016202105B2 (en) 2017-06-29
HUS2100024I1 (hu) 2021-07-28
EP3788874A1 (en) 2021-03-10
PL3172964T3 (pl) 2021-03-08
SMT201900149T1 (it) 2019-05-10
IL240283A (en) 2017-02-28
PT2755473T (pt) 2019-03-25
JP2014527081A (ja) 2014-10-09
EA032162B1 (ru) 2019-04-30
EP2755473B1 (en) 2018-12-12
ZA201401672B (en) 2015-02-25
FR21C1025I1 (fr) 2021-08-06
US20170020849A1 (en) 2017-01-26
WO2013039948A1 (en) 2013-03-21
AU2016202105A1 (en) 2016-04-28
US10786487B2 (en) 2020-09-29
MY198581A (en) 2023-09-06
US20210128533A1 (en) 2021-05-06
EA038853B1 (ru) 2021-10-28
HRP20201745T1 (hr) 2020-12-25
KR102081036B1 (ko) 2020-02-24
AU2012308776A1 (en) 2014-04-03
US20230087923A1 (en) 2023-03-23
DK3172964T3 (da) 2020-11-30
TWI632135B (zh) 2018-08-11
HUE042360T2 (hu) 2019-06-28
DK2755473T3 (en) 2019-03-11
EA026947B1 (ru) 2017-06-30
KR20200019793A (ko) 2020-02-24
BR112014005514B1 (pt) 2019-12-03
AR122776A2 (es) 2022-10-05
PL2755473T3 (pl) 2019-05-31
CY1123701T1 (el) 2021-09-14
PH12014500537A1 (en) 2014-04-21
CR20140117A (es) 2014-06-12
TW201702235A (zh) 2017-01-16
RS61048B1 (sr) 2020-12-31
EA201790094A1 (ru) 2017-05-31
IL249830B (en) 2019-08-29
KR101968489B1 (ko) 2019-04-12
LT2755473T (lt) 2019-03-12
MX2019003906A (es) 2019-12-09
CO6910187A2 (es) 2014-03-31
HUE052594T2 (hu) 2021-05-28
NZ725115A (en) 2018-08-31
JP6946528B2 (ja) 2021-10-06
NO2021026I1 (en) 2021-06-22
EP2755473A1 (en) 2014-07-23
LTC3172964I2 (me) 2023-03-10
IL240283A0 (en) 2015-09-24
CL2015000630A1 (es) 2015-07-17
US20160051519A1 (en) 2016-02-25
PT3172964T (pt) 2020-11-30
PE20142292A1 (es) 2015-01-10
TN2014000105A1 (en) 2015-07-01
BR112014005514A2 (pt) 2017-03-21
AP2014007508A0 (en) 2014-03-31
CN106474120B (zh) 2020-07-28
ES2715000T3 (es) 2019-05-31
JP6366102B2 (ja) 2018-08-01
LUC00211I2 (me) 2024-10-04
IL249830A0 (en) 2017-02-28
US11464763B2 (en) 2022-10-11
KR20140061530A (ko) 2014-05-21
US9180121B2 (en) 2015-11-10
AU2017228622B2 (en) 2019-02-28
CN106943399B (zh) 2020-07-28
FR21C1025I2 (fr) 2023-02-17
AU2012308776B2 (en) 2016-04-14
JP2020203891A (ja) 2020-12-24
CN103957701A (zh) 2014-07-30
ES2834427T3 (es) 2021-06-17
IL268295A (en) 2019-09-26
CY2021015I1 (el) 2021-10-15
SI2755473T1 (sl) 2019-03-29
AU2019203419A1 (en) 2019-06-06
AU2021204688A1 (en) 2021-07-29
JP2018154660A (ja) 2018-10-04
MY185280A (en) 2021-04-30
EP3172964A1 (en) 2017-05-31
TR201903499T4 (tr) 2019-04-22
EP3172964B1 (en) 2020-08-26
AU2017228622A1 (en) 2017-10-05
MA35431B1 (fr) 2014-09-01
NZ622466A (en) 2015-10-30
IN2014CN02128A (me) 2015-05-29
SG10201606670WA (en) 2016-10-28
HK1232073A1 (en) 2018-01-05
CA2848317C (en) 2021-01-19
US20130065846A1 (en) 2013-03-14
LT3172964T (lt) 2020-12-10
IL231358A0 (en) 2014-04-30
US10383854B2 (en) 2019-08-20
LTPA2021006I1 (me) 2021-07-12
US20190216784A1 (en) 2019-07-18
CY1121402T1 (el) 2020-05-29
AR117163A2 (es) 2021-07-14
CN106474120A (zh) 2017-03-08
US9877950B2 (en) 2018-01-30
MX364978B (es) 2019-05-16
IL231358A (en) 2016-04-21
AU2019203419B2 (en) 2021-04-08
CL2014000601A1 (es) 2014-10-10
AR087838A1 (es) 2014-04-23
SG11201400558YA (en) 2014-04-28
BR122019001738B1 (pt) 2019-11-05
SI3172964T1 (sl) 2020-12-31
PH12018501647A1 (en) 2019-02-27
NZ742345A (en) 2020-05-29
CN103957701B (zh) 2017-05-03
EA201892754A1 (ru) 2019-05-31
TWI567064B (zh) 2017-01-21
CR20180572A (es) 2019-02-01

Similar Documents

Publication Publication Date Title
CY2021015I2 (el) Παρασιτοκτονες συνθεσεις οι οποιες περιλαμβανουν εναν δραστικο παραγοντα ισοξαζολινης, μεθοδος και χρησεις αυτων
EP2699266A4 (en) COMPOSITIONS AND METHODS FOR STABILIZING ACTIVE SUBSTANCES
EP2758342A4 (en) CATALYST WITH LANTHANIDEDOTIC ZIRCONOXIDE AND METHOD FOR THE PRODUCTION THEREOF
EP2732291A4 (en) AKT-SPECIC INJECTION MAKERS, COMPOSITIONS AND METHOD FOR THEIR USE AND MANUFACTURE
EP2785668A4 (en) LIQUIDIZED COMPOSITIONS, MANUFACTURING METHOD AND USES THEREOF
ME03389B (me) Paraziticidne oralne veterinarske kompozicije које sadrže sistemski-delujuća aktivna sredstva, metodi i primene isтih
EP2582664A4 (en) PHENYL THIOACETATE COMPOUNDS AND COMPOSITIONS AND METHOD FOR THEIR USE
EP2736337A4 (en) CYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND METHOD OF USE THEREOF
MX353024B (es) Compuestos de fenil carbamato para uso en la prevencion o tratamiento de epilepsia.
EP2750677A4 (en) KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHOD OF USE THEREOF
FR2975004B1 (fr) Nouvel actif anti-rougeurs et compositions cosmetiques le comprenant
MX2014006136A (es) Uso de aril- y hetarilcarboxamidas como endoparasiticidas.
EP2792693A4 (en) FLUORATED COPOLYMER AND WATER- / OIL-REPELLENT MEDIUM WITH THIS COPOLYMER AS AN ACTIVE SUBSTANCE
EP2691396A4 (en) ENOPEPTINES, USES THEREOF AND SYNTHESIS METHOD THEREFOR
EP2749582A4 (en) FLUOROUS COPOLYMER AND SURFACE MODIFICATOR THEREFOR AS ACTIVE SUBSTANCE
EP2788489A4 (en) VECTORS WITH TOXIC GENES, METHODS AND USES THEREFOR
EP2785283A4 (en) ORTHOPEDIC IMPLANT WITH DYNAMIC TRANSFIXING SLOT
FR3012814B1 (fr) Composition polymere comprenant et liberant un compose actif odorant
EP2836478A4 (en) CORIOLUS VERSICOLOR EXTRACTS, METHOD FOR ISOLATING BIOLOGICALLY ACTIVE COMPOUNDS AND USES THEREOF
EP2802565A4 (en) COMPOUNDS, COMPOSITIONS AND RELATED PROCESSES USING 3-ARYL CHINOLINES
EP2663322A4 (en) NEW USES OF CYCLOPHILINE INHIBITORS
TR201203085A2 (tr) Sefetamet ve klavulanik asit içeren bileşimler.
TH1101003388B (th) องค์ประกอบ วิธีการและระบบเพื่อการส่งสารตัวกระทำปลุกฤทธิ์สองชนิดหรือมากกว่าทางการหายใจ
TR201203086A2 (tr) Sefiksim ve klavulanik asit içeren farmasötik dozaj formu.