ME02610B - Aklidinijum za upotrebu u poboljšanju kvaliteta sna kod respiratornih pacijenata - Google Patents
Aklidinijum za upotrebu u poboljšanju kvaliteta sna kod respiratornih pacijenataInfo
- Publication number
- ME02610B ME02610B MEP-2017-39A MEP201739A ME02610B ME 02610 B ME02610 B ME 02610B ME P201739 A MEP201739 A ME P201739A ME 02610 B ME02610 B ME 02610B
- Authority
- ME
- Montenegro
- Prior art keywords
- aclidinium
- sleep
- use according
- quality
- patients
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Paints Or Removers (AREA)
Claims (9)
1. Aklidinijum ili bilo koji od njegovih steroizomera ili smješe stereoizomera, ili njegova farmaceutski prihvatljiva so ili solvat, za upotrebu u poboljšanju kvaliteta sna kod respiratomih pacijenata.
2. Aklidinijum za upotrebu prema patentnom zahtjevu 1 , naznačen time da je aklidinijum u obliku aklidinijum bromida.
3. Aklidinijum za upotrebu prema patentnom zahtjevu 1 ili 2, gde respiratorni pacijent boluje od astme ili hronične opstruktivne bolesti pluća (HOBP).
4. Aklidinijum za upotrebu prema bilo kom od prethodnih patentnih zahtjeva, naznačen time što je aklidinijum u obliku formulacije suvog praška pogodne za inhalaciju.
5. Aklidinijum za upotrebu u formulaciji suvog praška prema patentnom zahtjevu 4, koja obezbeđuje odmerenu nominalnu dozu aklidinijuma ekvivalentnu sa dozom od 100 do 1000 mikrograma aklidinijum bromida po inhalaciji, poželjno 200 ili 400 mikrograma aklidinijum bromida.
6. Aklidinijum za upotrebu prema bilo kom od prethodnih patentnih zahtjeva, pri čemu se aklidinijum primjenjuje jednom ili više puta dnevno, poželjno dva puta dnevno.
7. Aklidinijum za upotrebu prema bilo kom od prethodnih patentnih zahtjeva, pri čemu se aklidinijum koprimenjuje sa terapeutski efikasnom količinom kortikosteroida, beta- adrenergičkog agoniste i/ili PDE4 inhibitora.
8. Aklidinijum za upotreu prema bilo kom od prethodnih patentnih zahtjeva, naznačen time daje kvalitet spavanja poboljšan redukcijom jednog ili više od sljedećih:a) Latencije u nastupanju sna b) Ukupnog broja buđenjae) Ranih buđenjad) Teškoće ostajanja u snu e) Površinskog snaf) Nesaniceg) Dnevne pospanosti ili zamorah) Ograničavanje aktivnosti tokom jutrai/ ili povećanje ukupnog vremena spavanja.
9. Farmaceutska kompozicija koja sadrži aklidinijum, kao što je definisano prema bilo kom od prethodnih patentnih zahtjeva, za upotrebu u poboljšanju kvaliteta sna kod respiratomih pacijenata, kao što je definisano u bilo kom prethodnom patentnom zahtjevu.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11382114A EP2510928A1 (en) | 2011-04-15 | 2011-04-15 | Aclidinium for use in improving the quality of sleep in respiratory patients |
| US201161497771P | 2011-06-16 | 2011-06-16 | |
| PCT/EP2012/056575 WO2012140081A1 (en) | 2011-04-15 | 2012-04-11 | Aclidinium for use in improving the quality of sleep in respiratory patients |
| EP12712699.3A EP2696871B1 (en) | 2011-04-15 | 2012-04-11 | Aclidinium for use in improving the quality of sleep in respiratory patients. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ME02610B true ME02610B (me) | 2017-06-20 |
Family
ID=44558460
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MEP-2017-39A ME02610B (me) | 2011-04-15 | 2012-04-11 | Aklidinijum za upotrebu u poboljšanju kvaliteta sna kod respiratornih pacijenata |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US20140100246A1 (me) |
| EP (2) | EP2510928A1 (me) |
| JP (1) | JP6322570B2 (me) |
| KR (1) | KR20140007929A (me) |
| CN (2) | CN107050024A (me) |
| AR (1) | AR085998A1 (me) |
| AU (1) | AU2012241858A1 (me) |
| BR (1) | BR112013024791A2 (me) |
| CA (1) | CA2826188A1 (me) |
| CL (1) | CL2013002996A1 (me) |
| CR (1) | CR20130532A (me) |
| CY (1) | CY1118786T1 (me) |
| DK (1) | DK2696871T3 (me) |
| EA (1) | EA201301168A1 (me) |
| ES (1) | ES2610104T3 (me) |
| GT (1) | GT201300249A (me) |
| HR (1) | HRP20170248T1 (me) |
| HU (1) | HUE031442T2 (me) |
| IL (1) | IL227666A0 (me) |
| LT (1) | LT2696871T (me) |
| ME (1) | ME02610B (me) |
| MX (1) | MX2013011772A (me) |
| PH (1) | PH12013501863A1 (me) |
| PL (1) | PL2696871T3 (me) |
| PT (1) | PT2696871T (me) |
| RS (1) | RS55731B1 (me) |
| SG (1) | SG193912A1 (me) |
| SI (1) | SI2696871T1 (me) |
| SM (2) | SMT201700098T1 (me) |
| UY (1) | UY34016A (me) |
| WO (1) | WO2012140081A1 (me) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
| WO2015091288A1 (en) * | 2013-12-19 | 2015-06-25 | Almirall S.A. | Aclidinium for use in the treatment of cough |
| WO2017108917A1 (en) * | 2015-12-22 | 2017-06-29 | Astrazeneca Ab | Pharmaceutical compositions for use in the treatment of chronic obstructive pulmonary disease |
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