HRP20200142T1 - Postupci i sastavi za liječenje depresije uporabom ciklobenzaprina - Google Patents
Postupci i sastavi za liječenje depresije uporabom ciklobenzaprina Download PDFInfo
- Publication number
- HRP20200142T1 HRP20200142T1 HRP20200142TT HRP20200142T HRP20200142T1 HR P20200142 T1 HRP20200142 T1 HR P20200142T1 HR P20200142T T HRP20200142T T HR P20200142TT HR P20200142 T HRP20200142 T HR P20200142T HR P20200142 T1 HRP20200142 T1 HR P20200142T1
- Authority
- HR
- Croatia
- Prior art keywords
- cyclobenzaprine
- use according
- administered
- medicine
- treating depression
- Prior art date
Links
- JURKNVYFZMSNLP-UHFFFAOYSA-N cyclobenzaprine Chemical compound C1=CC2=CC=CC=C2C(=CCCN(C)C)C2=CC=CC=C21 JURKNVYFZMSNLP-UHFFFAOYSA-N 0.000 title claims 14
- 229960003572 cyclobenzaprine Drugs 0.000 title claims 14
- 238000000034 method Methods 0.000 title claims 4
- 239000000203 mixture Substances 0.000 title 1
- 239000003814 drug Substances 0.000 claims 4
- 208000001640 Fibromyalgia Diseases 0.000 claims 2
- 230000001430 anti-depressive effect Effects 0.000 claims 1
- 239000000935 antidepressant agent Substances 0.000 claims 1
- 229940005513 antidepressants Drugs 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000006191 orally-disintegrating tablet Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Claims (6)
1. Ciklobenzaprin, naznačen time, da se upotrebljava u postupku liječenja depresije kod pacijenta s fibromijalgijom, pri čemu navedeni postupak obuhvaća davanje navedenog ciklobenzaprina pacijentu s fibromijalgijom, gdje liječenje s ciklobenzaprinom poboljšava stanje ili eliminira depresiju, te time, da je količina ciklobenzaprina koja se daje kao lijek, manja od 5 mg na dan.
2. Ciklobenzaprin za uporabu prema zahtjevu 1, naznačen time, da je količina ciklobenzaprina koja se daje kao lijek, manja od 2,5 mg na dan.
3. Ciklobenzaprin za uporabu prema zahtjevu 1, naznačen time, da postupak nadalje obuhvaća davanje jedne antidepresivne supstance uzastopno ili istodobno.
4. Ciklobenzaprin za uporabu prema zahtjevu 1, naznačen time, da se kod oblika doziranja koji se koristi za davanje ciklobenzaprina, radi o oralno rastapajućoj tableti ili o tankom sloju.
5. Ciklobenzaprin za uporabu prema zahtjevu 1, naznačen time, da se ciklobenzaprin daje kao lijek u kombinaciji s psihoterapeutskom intervencijom.
6. Ciklobenzaprin za uporabu prema zahtjevu 1, naznačen time, da se ciklobenzaprin daje kao lijek prije odlaska na spavanje.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161449838P | 2011-03-07 | 2011-03-07 | |
| PCT/US2012/027926 WO2012122193A1 (en) | 2011-03-07 | 2012-03-06 | Methods and compositions for treating depression using cyclobenzaprine |
| EP12755254.5A EP2683245B2 (en) | 2011-03-07 | 2012-03-06 | Methods and compositions for treating depression using cyclobenzaprine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20200142T1 true HRP20200142T1 (hr) | 2020-06-26 |
| HRP20200142T4 HRP20200142T4 (hr) | 2023-02-17 |
Family
ID=46796107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20200142TT HRP20200142T4 (hr) | 2011-03-07 | 2012-03-06 | Postupci i sastavi za liječenje depresije uporabom ciklobenzaprina |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20120232159A1 (hr) |
| EP (2) | EP2683245B2 (hr) |
| JP (2) | JP2014507475A (hr) |
| AU (4) | AU2012225548B2 (hr) |
| CA (1) | CA2829200C (hr) |
| CY (1) | CY1122998T1 (hr) |
| DK (1) | DK2683245T4 (hr) |
| ES (1) | ES2773834T5 (hr) |
| FI (1) | FI2683245T4 (hr) |
| HR (1) | HRP20200142T4 (hr) |
| HU (1) | HUE048596T2 (hr) |
| LT (1) | LT2683245T (hr) |
| PL (1) | PL2683245T5 (hr) |
| PT (1) | PT2683245T (hr) |
| RS (1) | RS60240B2 (hr) |
| SI (1) | SI2683245T2 (hr) |
| WO (1) | WO2012122193A1 (hr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO2501234T3 (hr) * | 2009-11-20 | 2018-02-10 | ||
| US20110319389A1 (en) | 2010-06-24 | 2011-12-29 | Tonix Pharmaceuticals, Inc. | Methods and compositions for treating fatigue associated with disordered sleep using very low dose cyclobenzaprine |
| US10117936B2 (en) | 2013-03-15 | 2018-11-06 | Tonix Pharma Holdings Limited | Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride |
| WO2015150948A1 (en) * | 2014-03-29 | 2015-10-08 | Wockhardt Limited | Modified release solid oral pharmaceutical compositions of cyclobenzaprine or a salt thereof |
| CN107072968B (zh) * | 2014-09-18 | 2021-01-12 | 通尼克斯制药控股有限公司 | 环苯扎林盐酸盐的低共熔混合物配制剂 |
| CN106890129A (zh) * | 2015-12-18 | 2017-06-27 | 健乔信元医药生技股份有限公司 | 环苄普林之延释剂型 |
| WO2019116091A1 (en) * | 2017-12-11 | 2019-06-20 | Tonix Pharma Holdings Limited | Cyclobenzaprine treatment for agitation, psychosis and cognitive decline in dementia and neurodegenerative conditions |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| US5354566A (en) | 1993-06-02 | 1994-10-11 | Kraft General Foods, Inc. | Preparation of yeast-leavened dough crusts |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| US6761903B2 (en) | 1999-06-30 | 2004-07-13 | Lipocine, Inc. | Clear oil-containing pharmaceutical compositions containing a therapeutic agent |
| US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US6267985B1 (en) | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| US6383471B1 (en) | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
| US6309663B1 (en) | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
| ES2212737B1 (es) * | 1999-08-13 | 2005-10-01 | Vela Pharmaceuticals Inc. | Ciclobenzaprina para tratar trastornos de ansiedad generalizada y composiciones de la misma. |
| US6395788B1 (en) * | 1999-08-13 | 2002-05-28 | Vela Pharmaceuticals, Inc. | Methods and compositions for treating or preventing sleep disturbances and associated illnesses using very low doses of cyclobenzaprine |
| US6720001B2 (en) | 1999-10-18 | 2004-04-13 | Lipocine, Inc. | Emulsion compositions for polyfunctional active ingredients |
| BRPI0415683A (pt) * | 2003-11-03 | 2006-12-19 | Warner Lambert Co | inibidores da reabsorção de norepinefrina para o tratamento de distúrbios do sistema nervoso central |
| US20050143350A1 (en) * | 2003-11-19 | 2005-06-30 | Seed John C. | Combination drug therapy to treat obesity |
| US7532935B2 (en) * | 2005-07-29 | 2009-05-12 | Cyberonics, Inc. | Selective neurostimulation for treating mood disorders |
| US7994220B2 (en) * | 2005-09-28 | 2011-08-09 | Cypress Bioscience, Inc. | Milnacipran for the long-term treatment of fibromyalgia syndrome |
| CA2905541C (en) * | 2008-01-09 | 2020-02-11 | Charleston Laboratories, Inc. | Pharmaceutical compositions comprising an antiemetic and an opioid analgesic |
-
2012
- 2012-03-05 US US13/412,571 patent/US20120232159A1/en active Pending
- 2012-03-06 HR HRP20200142TT patent/HRP20200142T4/hr unknown
- 2012-03-06 HU HUE12755254A patent/HUE048596T2/hu unknown
- 2012-03-06 AU AU2012225548A patent/AU2012225548B2/en active Active
- 2012-03-06 RS RS20200155A patent/RS60240B2/sr unknown
- 2012-03-06 FI FIEP12755254.5T patent/FI2683245T4/fi active
- 2012-03-06 PT PT127552545T patent/PT2683245T/pt unknown
- 2012-03-06 EP EP12755254.5A patent/EP2683245B2/en active Active
- 2012-03-06 ES ES12755254T patent/ES2773834T5/es active Active
- 2012-03-06 EP EP19214568.8A patent/EP3682885A1/en not_active Withdrawn
- 2012-03-06 SI SI201231736T patent/SI2683245T2/sl unknown
- 2012-03-06 DK DK12755254.5T patent/DK2683245T4/da active
- 2012-03-06 PL PL12755254.5T patent/PL2683245T5/pl unknown
- 2012-03-06 CA CA2829200A patent/CA2829200C/en active Active
- 2012-03-06 LT LTEP12755254.5T patent/LT2683245T/lt unknown
- 2012-03-06 WO PCT/US2012/027926 patent/WO2012122193A1/en active Application Filing
- 2012-03-06 JP JP2013557811A patent/JP2014507475A/ja active Pending
-
2016
- 2016-01-18 JP JP2016007041A patent/JP2016053095A/ja active Pending
- 2016-08-31 AU AU2016222412A patent/AU2016222412B2/en active Active
-
2018
- 2018-06-26 AU AU2018204633A patent/AU2018204633C1/en active Active
-
2020
- 2020-02-05 CY CY20201100112T patent/CY1122998T1/el unknown
- 2020-06-11 AU AU2020203874A patent/AU2020203874B2/en active Active
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