HRP20171739T1 - Postupci i kompozicije za liječenje simptoma povezanih s posttraumatskim stresnim poremećajem korištenjem ciklobenzaprina - Google Patents

Postupci i kompozicije za liječenje simptoma povezanih s posttraumatskim stresnim poremećajem korištenjem ciklobenzaprina Download PDF

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Publication number
HRP20171739T1
HRP20171739T1 HRP20171739TT HRP20171739T HRP20171739T1 HR P20171739 T1 HRP20171739 T1 HR P20171739T1 HR P20171739T T HRP20171739T T HR P20171739TT HR P20171739 T HRP20171739 T HR P20171739T HR P20171739 T1 HRP20171739 T1 HR P20171739T1
Authority
HR
Croatia
Prior art keywords
pharmaceutical composition
therapeutically effective
cyclobenzaprine
effective amount
use according
Prior art date
Application number
HRP20171739TT
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English (en)
Inventor
Seth Lederman
Herb Harris
Original Assignee
Tonix Pharma Holdings Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44059887&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20171739(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tonix Pharma Holdings Limited filed Critical Tonix Pharma Holdings Limited
Publication of HRP20171739T1 publication Critical patent/HRP20171739T1/hr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/131—Amines acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Claims (8)

1. Farmaceutska kompozicija koja sadrži ciklobenzaprin u terapeutski efikasnoj količini i terapeutski efikasan nosač, za upotrebu u postupku za liječenje razvoja simptoma posttraumatskog stresnog poremećaja (PTSD), ili pojave simptoma PTSD, ili konsolidacije simptoma PTSD, ili održavanja simptoma PTSD koji se javlja nakon traumatskog događaja, koji obuhvaća primjenu kod čovjeka kome je takvo liječenje potrebno navedene farmaceutske kompozicije, pri čemu takvo liječenje otklanja ili poboljšava simptom PTSD, naznačena time što je terapeutski efikasna količina primijenjenog ciklobenzaprina između 0.5 mg i 50 mg/dan.
2. Farmaceutska kompozicija za upotrebu prema patentnom zahtjevu 1, naznačena time što je terapeutski efikasna količina primijenjenog ciklobenzaprina manja od 10 mg/dan.
3. Farmaceutska kompozicija za upotrebu prema patentnom zahtjevu 1, naznačena time što se farmaceutska kompozicija primjenjuje kao tableta koja se otapa oralno ili kao formulacija tankog filma.
4. Farmaceutska kompozicija za upotrebu prema patentnom zahtjevu 1, koja dodatno sadrži lijek odabran iz grupe koja se sastoji od antagonista alfa-1-adrenergičkog receptora, beta-adrenergičkog antagonista, antikonvulzanta, selijektivnog inhibitora ponovnog preuzimanja serotonina ili inhibitora ponovnog preuzimanja serotonina i norepinefrina.
5. Farmaceutska kompozicija za upotrebu prema patentnom zahtjevu 4, naznačena time što je farmaceutska kompozicija tableta koja se otapa oralno ili formulacija tankog filma.
6. Farmaceutska kompozicija koja sadrži ciklobenzaprin u terapeutski efikasnoj količini i terapeutski efikasan nosač za upotrebu u postupku za liječenje poremećaja sna ili poremećaja koji nije povezan sa snom udruženog sa posttraumatskim stresnim poremećajem (PTSD), koji obuhvaća primjenu kod čovjeka kome je takvo liječenje potrebno navedene farmaceutske kompozicije, pri čemu takvo liječenje poboljšava ili otklanja poremećaj koji nije povezan sa snom, naznačena time što je terapeutski efikasna količina primijenjenog ciklobenzaprina između 0.5 mg i 50 mg/dan.
7. Farmaceutska kompozicija za upotrebu prema patentnom zahtjevu 6, naznačena time što je terapeutski efikasna količina primijenjenog ciklobenzaprina manja od 10 mg/dan.
8. Farmaceutska kompozicija za upotrebu prema patentnom zahtjevu 6, naznačena time što se farmaceutska kompozicija primjenjuje kao tableta koja se otapa oralno ili kao formulacija tankog filma.
HRP20171739TT 2009-11-20 2017-11-13 Postupci i kompozicije za liječenje simptoma povezanih s posttraumatskim stresnim poremećajem korištenjem ciklobenzaprina HRP20171739T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28166109P 2009-11-20 2009-11-20
EP10831895.7A EP2501234B1 (en) 2009-11-20 2010-11-16 Methods and compositions for treating symptoms associated with post-traumatic stress disorder using cyclobenzaprine
PCT/US2010/002979 WO2011062614A1 (en) 2009-11-20 2010-11-16 Methods and compositions for treating symptoms associated with post-traumatic stress disorder using cyclobenzaprine

Publications (1)

Publication Number Publication Date
HRP20171739T1 true HRP20171739T1 (hr) 2018-03-09

Family

ID=44059887

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20171739TT HRP20171739T1 (hr) 2009-11-20 2017-11-13 Postupci i kompozicije za liječenje simptoma povezanih s posttraumatskim stresnim poremećajem korištenjem ciklobenzaprina

Country Status (14)

Country Link
US (2) US9918948B2 (hr)
EP (1) EP2501234B1 (hr)
CY (1) CY1119698T1 (hr)
DK (1) DK2501234T3 (hr)
ES (1) ES2649022T3 (hr)
HR (1) HRP20171739T1 (hr)
HU (1) HUE037281T2 (hr)
LT (1) LT2501234T (hr)
NO (1) NO2501234T3 (hr)
PL (1) PL2501234T3 (hr)
PT (1) PT2501234T (hr)
RS (1) RS56634B1 (hr)
SI (1) SI2501234T1 (hr)
WO (1) WO2011062614A1 (hr)

Families Citing this family (12)

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CN114736305B (zh) 2014-01-10 2023-05-05 比奥贝拉蒂治疗公司 因子viii嵌合蛋白及其用途
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Also Published As

Publication number Publication date
DK2501234T3 (en) 2017-12-04
US20180193288A1 (en) 2018-07-12
EP2501234A1 (en) 2012-09-26
NO2501234T3 (hr) 2018-02-10
US9918948B2 (en) 2018-03-20
PT2501234T (pt) 2017-12-13
LT2501234T (lt) 2017-12-11
EP2501234B1 (en) 2017-09-13
US20110124656A1 (en) 2011-05-26
ES2649022T3 (es) 2018-01-09
PL2501234T3 (pl) 2018-01-31
SI2501234T1 (en) 2018-02-28
HUE037281T2 (hu) 2018-08-28
WO2011062614A1 (en) 2011-05-26
CY1119698T1 (el) 2018-04-04
EP2501234A4 (en) 2013-04-24
RS56634B1 (sr) 2018-03-30

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