MD4735B1 - Derivaţi ai pirolo[2,3-d]pirimidinei ca inhibitori de Kinaze Janus-asociate (JAK) - Google Patents

Derivaţi ai pirolo[2,3-d]pirimidinei ca inhibitori de Kinaze Janus-asociate (JAK) Download PDF

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Publication number
MD4735B1
MD4735B1 MDA20150073A MD20150073A MD4735B1 MD 4735 B1 MD4735 B1 MD 4735B1 MD A20150073 A MDA20150073 A MD A20150073A MD 20150073 A MD20150073 A MD 20150073A MD 4735 B1 MD4735 B1 MD 4735B1
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Moldova
Prior art keywords
pyrimidine derivatives
jak
pyrrolo
inhibitors
janus
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MDA20150073A
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English (en)
Russian (ru)
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MD4735C1 (ro
MD20150073A2 (ro
Inventor
Мэттью Фрэнк Браун
Эшли Эдвард ФЕНВИК
Марк Эдвард Флэнаган
Андреа Гонсалес
Тимоти Аллан Джонсон
Неелу КАЙЛА
Марк Дж. Миттон-Фрай
Джозеф Уолтер Стробах
Рут Е. Тенбринк
Джон Дэвид Тшупек
Райоманд Джал Унвалла
Майкл Л. Васкес
Михир Д. Парих
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Pfizer Inc.
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Publication of MD20150073A2 publication Critical patent/MD20150073A2/ro
Publication of MD4735B1 publication Critical patent/MD4735B1/ro
Publication of MD4735C1 publication Critical patent/MD4735C1/ro

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Abstract

Invenţia se referă la derivaţi ai pirolo[2,3-d]pirimidinei farmaceutic activi. Conform invenţiei, se revendică derivaţi ai pirolo[2,3-d]pirimidinei cu formula IA: De asemenea, se revendică utilizarea lor în calitate de inhibitori de Kinaze Janus (JAK) şi compoziţii farmaceutice care îi conţin.
MDA20150073A 2013-02-22 2014-02-11 Derivaţi ai pirolo[2,3-d]pirimidinei ca inhibitori de Kinaze Janus-asociate (JAK) MD4735C1 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361767947P 2013-02-22 2013-02-22
PCT/IB2014/058889 WO2014128591A1 (en) 2013-02-22 2014-02-11 Pyrrolo [2, 3 -d]pyrimidine derivatives as inhibitors of janus- related kinases (jak)

Publications (3)

Publication Number Publication Date
MD20150073A2 MD20150073A2 (ro) 2016-01-31
MD4735B1 true MD4735B1 (ro) 2020-12-31
MD4735C1 MD4735C1 (ro) 2021-07-31

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MDA20150073A MD4735C1 (ro) 2013-02-22 2014-02-11 Derivaţi ai pirolo[2,3-d]pirimidinei ca inhibitori de Kinaze Janus-asociate (JAK)

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US (3) US9035074B2 (ro)
EP (2) EP2958921B1 (ro)
JP (2) JP6145179B2 (ro)
KR (1) KR101787858B1 (ro)
CN (2) CN107089985B (ro)
AP (1) AP2015008664A0 (ro)
AR (1) AR094857A1 (ro)
AU (1) AU2014220357B2 (ro)
BR (1) BR112015019634B1 (ro)
CA (1) CA2900703C (ro)
CL (1) CL2015002303A1 (ro)
CR (1) CR20150395A (ro)
CU (1) CU24275B1 (ro)
CY (3) CY1119502T1 (ro)
DK (2) DK3290421T3 (ro)
DO (1) DOP2015000206A (ro)
EA (1) EA027879B1 (ro)
ES (2) ES2713052T3 (ro)
FR (1) FR22C1006I2 (ro)
GE (1) GEP201606600B (ro)
HR (2) HRP20171599T2 (ro)
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IL (1) IL240132B (ro)
LT (3) LT2958921T (ro)
LU (1) LUC00261I2 (ro)
MA (1) MA38347A1 (ro)
MD (1) MD4735C1 (ro)
ME (2) ME03301B (ro)
MX (1) MX374338B (ro)
MY (1) MY177476A (ro)
NL (1) NL301155I2 (ro)
NO (2) NO3052752T3 (ro)
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PE (1) PE20151764A1 (ro)
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PL (2) PL2958921T3 (ro)
PT (2) PT2958921T (ro)
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RS (2) RS58245B1 (ro)
SG (1) SG11201505816UA (ro)
SI (2) SI2958921T1 (ro)
TN (1) TN2015000355A1 (ro)
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UA (1) UA111804C2 (ro)
UY (1) UY35337A (ro)
WO (1) WO2014128591A1 (ro)
ZA (1) ZA201505454B (ro)

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