MC1983A1 - Composes heterocycliques,leur preparation et medicaments qui contiennent de tels composes - Google Patents
Composes heterocycliques,leur preparation et medicaments qui contiennent de tels composesInfo
- Publication number
- MC1983A1 MC1983A1 MC882012A MC2012A MC1983A1 MC 1983 A1 MC1983 A1 MC 1983A1 MC 882012 A MC882012 A MC 882012A MC 2012 A MC2012 A MC 2012A MC 1983 A1 MC1983 A1 MC 1983A1
- Authority
- MC
- Monaco
- Prior art keywords
- aryl
- alkyl
- group
- compounds
- benzyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fats And Perfumes (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878724912A GB8724912D0 (en) | 1987-10-23 | 1987-10-23 | Indole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MC1983A1 true MC1983A1 (fr) | 1989-11-23 |
Family
ID=10625806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MC882012A MC1983A1 (fr) | 1987-10-23 | 1988-10-21 | Composes heterocycliques,leur preparation et medicaments qui contiennent de tels composes |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0313397B1 (fr) |
| JP (1) | JP2501631B2 (fr) |
| CN (1) | CN1035113A (fr) |
| AT (1) | ATE90089T1 (fr) |
| AU (1) | AU604165B2 (fr) |
| DD (1) | DD283140A5 (fr) |
| DE (1) | DE3881472T2 (fr) |
| DK (1) | DK586588A (fr) |
| ES (1) | ES2054825T3 (fr) |
| FI (1) | FI884879A (fr) |
| GB (1) | GB8724912D0 (fr) |
| HU (1) | HU202230B (fr) |
| IL (1) | IL88122A0 (fr) |
| MC (1) | MC1983A1 (fr) |
| NZ (1) | NZ226671A (fr) |
| PL (1) | PL158305B1 (fr) |
| PT (1) | PT88829B (fr) |
| ZA (1) | ZA887900B (fr) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT95899A (pt) * | 1989-11-17 | 1991-09-13 | Glaxo Group Ltd | Processo para a preparacao de derivados indole |
| IL96891A0 (en) * | 1990-01-17 | 1992-03-29 | Merck Sharp & Dohme | Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them |
| DE4010797A1 (de) * | 1990-04-04 | 1991-10-10 | Hoechst Ag | Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung |
| IL98392A (en) * | 1990-06-07 | 1996-01-19 | Wellcome Found | History of indole, their preparation and the pharmaceutical preparations containing them |
| EP0494774A1 (fr) * | 1991-01-11 | 1992-07-15 | MERCK SHARP & DOHME LTD. | Composés hétéroaromatiques à 5 chaînons substitués par l'indazole |
| US5317103A (en) * | 1991-01-15 | 1994-05-31 | Merck Sharp & Dohme Limited | Indole-substituted five-membered heteroaromatic compounds as 5-HT1 agonists |
| SK278998B6 (sk) * | 1991-02-01 | 1998-05-06 | Merck Sharp & Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu, spôsob i |
| TW263508B (fr) * | 1991-02-12 | 1995-11-21 | Pfizer | |
| GB9104136D0 (en) * | 1991-02-27 | 1991-04-17 | Merck Sharp & Dohme | Therapeutic agents |
| UA41297C2 (uk) * | 1991-11-25 | 2001-09-17 | Пфайзер, Інк. | Похідні індолу, фармацевтична композиція і спосіб лікування |
| CA2083891A1 (fr) * | 1991-12-03 | 1993-06-04 | Angus Murray Macleod | Composes heterocycliques, compositions et utilisation therapeutique |
| US5409941A (en) * | 1992-02-03 | 1995-04-25 | Pfizer Inc. | 5-heteroyl indole derivatives |
| TW288010B (fr) * | 1992-03-05 | 1996-10-11 | Pfizer | |
| CA2129146A1 (fr) * | 1992-03-13 | 1993-09-16 | Victor Giulio Matassa | Derives de l'imidazole, du triazole et du tetrazole |
| GB9207396D0 (en) * | 1992-04-03 | 1992-05-13 | Merck Sharp & Dohme | Therapeutic agents |
| PL172405B1 (en) | 1992-04-07 | 1997-09-30 | Pfizer | Derivatives of indole |
| US6380233B1 (en) | 1992-04-07 | 2002-04-30 | Pfizer Inc | Indole derivatives as 5-HT1 agonists |
| DE69307875T2 (de) * | 1992-04-10 | 1997-05-22 | Pfizer | Acylaminoindolderivate als 5-ht1 agonisten |
| GB9207930D0 (en) * | 1992-04-10 | 1992-05-27 | Pfizer Ltd | Indoles |
| GB9208463D0 (en) * | 1992-04-16 | 1992-06-03 | Merck Sharp & Dohme | Therapeutic agents |
| GB9210400D0 (en) * | 1992-05-15 | 1992-07-01 | Merck Sharp & Dohme | Therapeutic agents |
| GB9211277D0 (en) | 1992-05-28 | 1992-07-15 | Glaxo Group Inc | Pharmaceutical compositions |
| KR100286411B1 (ko) * | 1992-06-05 | 2001-04-16 | 더블유. 지. 콜 | 치환된 트리아졸의 설페이트 염, 이의 제조방법 및 이를 포함하는 약제학적 조성물 |
| GB9215526D0 (en) * | 1992-07-22 | 1992-09-02 | Merck Sharp & Dohme | Chemical process |
| CA2138649A1 (fr) * | 1992-07-24 | 1994-02-03 | Raymond Baker | Derives imidazole, triazole et tetrazole |
| IL106445A (en) * | 1992-07-30 | 1998-01-04 | Merck Sharp & Dohme | History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them |
| TW251284B (fr) * | 1992-11-02 | 1995-07-11 | Pfizer | |
| GB9226537D0 (en) * | 1992-12-21 | 1993-02-17 | Smithkline Beecham Plc | Compounds |
| LT3594B (en) | 1993-07-29 | 1995-12-27 | Merck Sharp & Dohme | Imidazole,triazole and tetrazole derivatives |
| ES2070087B1 (es) * | 1993-08-13 | 1996-02-16 | Pfizer | Derivados de indol |
| US6423731B2 (en) | 1994-01-06 | 2002-07-23 | Zeneca Limited | Indole derivatives as prodrugs of 5-HT1-like receptor agonists |
| GB9401436D0 (en) * | 1994-01-26 | 1994-03-23 | Wellcome Found | Therapeutic heterocyclic compounds |
| GB9407447D0 (en) * | 1994-04-14 | 1994-06-08 | Glaxo Group Ltd | Chemical compounds |
| WO1995032966A1 (fr) * | 1994-06-01 | 1995-12-07 | Zeneca Limited | Derives d'indole utilises comme promedicaments contenant des agonistes de recepteurs apparentes au 5-ht¿1? |
| EP0773942A1 (fr) * | 1994-07-26 | 1997-05-21 | Pfizer Inc. | Derives 4-indole utilises comme agonistes et antagonistes de la serotonine |
| WO1996017842A1 (fr) * | 1994-12-06 | 1996-06-13 | Merck Sharp & Dohme Limited | Derives de l'azetidine, de la pyrrolidine et de la piperidine utilises comme agonistes des recepteurs 5-ht1 |
| GB9516143D0 (en) | 1995-08-07 | 1995-10-04 | Wellcome Found | Improved chemical synthesis |
| GB9516145D0 (en) * | 1995-08-07 | 1995-10-04 | Wellcome Found | Improved chemical synthesis |
| US6909005B1 (en) | 1995-08-07 | 2005-06-21 | Astrazeneca Uk Limited | One post synthesis of 2-oxazolidinone derivatives |
| US5998438A (en) * | 1996-11-26 | 1999-12-07 | Allelix Biopharmaceuticals, Inc. | 5-cyclo indole compounds |
| US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
| WO2000000490A2 (fr) * | 1998-06-26 | 2000-01-06 | Eli Lilly And Company | Agonistes de 5-ht¿1f? |
| CN1662538A (zh) | 2002-06-21 | 2005-08-31 | 苏文生命科学有限公司 | 可作为治疗剂的对血清素受体具有亲和力的芳烷基吲哚、其制备工艺及其含有该物质的药物组合物 |
| MXPA04012832A (es) | 2002-06-21 | 2005-05-27 | Suven Life Sciences Ltd | Arilsulfonil indoles novedosos que tienen afinidad por el receptor de la serotonina, utiles como agentes terapeuticos, proceso para su preparacion y composiciones farmaceuticas que los contienen. |
| CA2509982C (fr) | 2002-11-28 | 2011-11-08 | Suven Life Sciences Limited | Indoles n-arylsulfonyl-3-substitues presentant une affinite pour le recepteur de la serotonine, methode de preparation et composition pharmaceutique contenant ces indoles |
| AU2003285759B2 (en) | 2002-11-28 | 2010-01-28 | Suven Life Sciences Limited | N-arylsulfonyl-3-aminoalkoxyindoles |
| NZ540841A (en) | 2002-12-18 | 2008-08-29 | Suven Life Sciences Ltd | Tetracyclic 3-substituted indoles having serotonin receptor affinity |
| DE102005018191A1 (de) | 2005-04-19 | 2006-10-26 | Grünenthal GmbH | Substituierte zyklische Harnstoff-Derivate und deren Verwendung zur Herstellung von Arzneimitteln |
| JP7126260B2 (ja) | 2016-01-27 | 2022-08-26 | インスター テクノロジーズ アクチオヴァ スプルチュノスト | 治療処置用の口腔粘膜ナノファイバ担体 |
| CN112759550A (zh) * | 2019-11-04 | 2021-05-07 | 上海科技大学 | 一种平滑受体拮抗剂 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0225726B1 (fr) | 1985-11-08 | 1991-04-17 | Glaxo Group Limited | Dérivés de l'indole |
| GB8600397D0 (en) | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
-
1987
- 1987-10-23 GB GB878724912A patent/GB8724912D0/en active Pending
-
1988
- 1988-10-21 ZA ZA887900A patent/ZA887900B/xx unknown
- 1988-10-21 PL PL1988275423A patent/PL158305B1/pl unknown
- 1988-10-21 PT PT88829A patent/PT88829B/pt not_active IP Right Cessation
- 1988-10-21 HU HU885431A patent/HU202230B/hu unknown
- 1988-10-21 CN CN88108816A patent/CN1035113A/zh active Pending
- 1988-10-21 IL IL88122A patent/IL88122A0/xx unknown
- 1988-10-21 JP JP63265917A patent/JP2501631B2/ja not_active Expired - Lifetime
- 1988-10-21 ES ES88309943T patent/ES2054825T3/es not_active Expired - Lifetime
- 1988-10-21 DE DE88309943T patent/DE3881472T2/de not_active Expired - Fee Related
- 1988-10-21 EP EP88309943A patent/EP0313397B1/fr not_active Expired - Lifetime
- 1988-10-21 DK DK586588A patent/DK586588A/da not_active Application Discontinuation
- 1988-10-21 AT AT88309943T patent/ATE90089T1/de not_active IP Right Cessation
- 1988-10-21 MC MC882012A patent/MC1983A1/fr unknown
- 1988-10-21 FI FI884879A patent/FI884879A/fi not_active Application Discontinuation
- 1988-10-21 DD DD88320940A patent/DD283140A5/de not_active IP Right Cessation
- 1988-10-21 NZ NZ226671A patent/NZ226671A/xx unknown
- 1988-10-24 AU AU24181/88A patent/AU604165B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0313397B1 (fr) | 1993-06-02 |
| FI884879A (fi) | 1989-04-24 |
| DK586588A (da) | 1989-04-24 |
| PL158305B1 (en) | 1992-08-31 |
| JPH01146882A (ja) | 1989-06-08 |
| JP2501631B2 (ja) | 1996-05-29 |
| FI884879A0 (fi) | 1988-10-21 |
| EP0313397A1 (fr) | 1989-04-26 |
| DD283140A5 (de) | 1990-10-03 |
| DK586588D0 (da) | 1988-10-21 |
| DE3881472D1 (de) | 1993-07-08 |
| CN1035113A (zh) | 1989-08-30 |
| AU604165B2 (en) | 1990-12-06 |
| ES2054825T3 (es) | 1994-08-16 |
| PT88829B (pt) | 1993-01-29 |
| HU202230B (en) | 1991-02-28 |
| IL88122A0 (en) | 1989-06-30 |
| HUT50163A (en) | 1989-12-28 |
| AU2418188A (en) | 1989-04-27 |
| ZA887900B (en) | 1990-06-27 |
| NZ226671A (en) | 1991-09-25 |
| ATE90089T1 (de) | 1993-06-15 |
| GB8724912D0 (en) | 1987-11-25 |
| DE3881472T2 (de) | 1993-12-16 |
| PL275423A1 (en) | 1989-08-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MC1983A1 (fr) | Composes heterocycliques,leur preparation et medicaments qui contiennent de tels composes | |
| DE10199003I2 (fr) | ||
| FI950016A (fi) | Heterosykliset yhdisteet lääkeaineena | |
| ATE79376T1 (de) | Dithioacetal-verbindungen, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
| IL68494A (en) | Dihydropyridine derivatives,their production and pharmaceutical compositions comprising them | |
| NO171365C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater | |
| NO163855C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive arylcyklobutylalkylaminer. | |
| FR2669927B1 (fr) | Nouveaux derives de guanidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. | |
| ES8403887A1 (es) | Procedimiento de obtencion de los 2-amino 5- (aralcoil piperidino alcoil) amino 1,4-diazoles | |
| HUT43068A (en) | Process for preparing 5-amino-alkyl-beta-carboline derivatives and pharmaceutical compositions containing them | |
| HUP0002054A2 (hu) | N-4-(nitro-metil-szulfonil)-fenil-alkánamid és -benzolszulfonamid-származékok, alkalmazásuk, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| YP | Annual fee paid |