MA55695A - Composés chimiques comme inhibiteurs de l'activité interleukine-1 - Google Patents
Composés chimiques comme inhibiteurs de l'activité interleukine-1Info
- Publication number
- MA55695A MA55695A MA055695A MA55695A MA55695A MA 55695 A MA55695 A MA 55695A MA 055695 A MA055695 A MA 055695A MA 55695 A MA55695 A MA 55695A MA 55695 A MA55695 A MA 55695A
- Authority
- MA
- Morocco
- Prior art keywords
- interleukin
- inhibitors
- activity
- chemical compounds
- compounds
- Prior art date
Links
- 102000000589 Interleukin-1 Human genes 0.000 title 1
- 108010002352 Interleukin-1 Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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- A61K31/415—1,2-Diazoles
- A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
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- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Immunology (AREA)
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- Diabetes (AREA)
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- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762449431P | 2017-01-23 | 2017-01-23 | |
| US201762492813P | 2017-05-01 | 2017-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA55695A true MA55695A (fr) | 2022-02-23 |
Family
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| MA055695A MA55695A (fr) | 2017-01-23 | 2018-01-22 | Composés chimiques comme inhibiteurs de l'activité interleukine-1 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
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| MA047308A MA47308A (fr) | 2017-01-23 | 2018-01-22 | Composés chimiques comme inhibiteurs de l'activité interleukine-1 |
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| UA126675C2 (uk) | 2017-01-23 | 2023-01-11 | Дженентек, Інк. | Хімічні сполуки як інгібітори активності інтерлейкіну-1 |
| JP7072586B2 (ja) | 2017-05-24 | 2022-05-20 | ザ ユニバーシティ オブ クィーンズランド | 新規な化合物及び使用 |
| PT3661925T (pt) | 2017-07-07 | 2022-01-31 | Inflazome Ltd | Novos compostos de sulfonamida-carboxamida |
| CN117209447A (zh) | 2017-07-24 | 2023-12-12 | 诺华股份有限公司 | 用于治疗与nlrp活性相关的病症的化合物和组合物 |
| BR112020002906A2 (pt) | 2017-08-15 | 2020-08-04 | Inflazome Limited | novos compostos de sulfonamida-carboxamida |
| WO2019034692A1 (en) * | 2017-08-15 | 2019-02-21 | Inflazome Limited | SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3 |
| WO2019034697A1 (en) * | 2017-08-15 | 2019-02-21 | Inflazome Limited | NOVEL CARBOXAMIDE SULFONAMIDE COMPOUNDS |
| UY37847A (es) * | 2017-08-15 | 2019-03-29 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas útiles como inhibidores de nlrp3 |
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| EP3707137A1 (en) | 2017-11-09 | 2020-09-16 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| MX2020004423A (es) | 2017-11-09 | 2020-08-06 | Inflazome Ltd | Nuevos compuestos de sulfonamida carboxamida. |
| EP3759077A1 (en) * | 2018-03-02 | 2021-01-06 | Inflazome Limited | Novel compounds |
| EP3759073A1 (en) | 2018-03-02 | 2021-01-06 | Inflazome Limited | Sulfonamide derivates as nlrp3 inhibitors |
| WO2019166627A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
| MA52489A (fr) | 2018-05-04 | 2021-03-10 | Inflazome Ltd | Nouveaux composés |
| WO2020018970A1 (en) * | 2018-07-20 | 2020-01-23 | Genentech, Inc. | Sulfonylurea compounds as inhibitors of interleukin-1 activity |
| PE20211811A1 (es) * | 2018-07-20 | 2021-09-14 | Hoffmann La Roche | Compuestos de sulfonimidamida como inhibidores de la actividad de interleucina-1 |
| PE20211333A1 (es) | 2018-08-15 | 2021-07-22 | Inflazome Ltd | Compuestos de sulfonamidaurea novedosos |
| GB201902327D0 (en) | 2019-02-20 | 2019-04-03 | Inflazome Ltd | Novel compounds |
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| CN113166081A (zh) | 2018-11-13 | 2021-07-23 | 诺华股份有限公司 | 用于治疗与nlrp活性相关的病症的化合物和组合物 |
| ES2974842T3 (es) | 2018-11-13 | 2024-07-01 | Novartis Ag | Compuestos y composiciones para el tratamiento de afecciones asociadas a la actividad de nlrp |
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| FI3911631T3 (fi) | 2019-01-14 | 2025-02-03 | Zydus Lifesciences Ltd | Uusia substituoituja sulfonyyliureajohdannaisia |
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| EP3986879B1 (en) | 2019-06-21 | 2024-10-02 | AC Immune SA | Fused 1,2-thiazoles and 1,2-thiazines which act as nlrp3 modulators |
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| BR112022000855A2 (pt) | 2019-07-17 | 2022-06-21 | Zomagen Biosciences Ltd | Moduladores de nlrp3 |
| JP2022545400A (ja) | 2019-08-16 | 2022-10-27 | インフレイゾーム リミテッド | Nlrp3阻害剤として有用な大環状スルホニル尿素誘導体 |
| WO2021043966A1 (en) | 2019-09-06 | 2021-03-11 | Inflazome Limited | Nlrp3 inhibitors |
| AU2020383646B2 (en) | 2019-11-12 | 2023-10-12 | Kangbaida (Sichuan) Biotechnology Co., Ltd. | Amide derivative and preparation method therefore and use thereof in medicine |
| MX2022009043A (es) * | 2020-01-22 | 2022-08-11 | Hoffmann La Roche | Compuestos de sulfonimidamida como moduladores de nlrp3. |
| WO2021165245A1 (en) | 2020-02-18 | 2021-08-26 | Inflazome Limited | Compounds |
| US11603375B2 (en) * | 2020-03-16 | 2023-03-14 | Zomagen Biosciences Ltd | NLRP3 modulators |
| WO2021203014A1 (en) | 2020-04-03 | 2021-10-07 | Vertex Pharmaceuticals Incorporated | Pyrano[4,3-b]l ndole derivatives as alpha-1 -antitrypsin modulators for treating alpha-1 -antitrypsin deficiency (aatd) |
| CN115485280A (zh) * | 2020-04-30 | 2022-12-16 | 詹森药业有限公司 | 新三嗪并吲哚化合物 |
| KR20230028425A (ko) | 2020-06-19 | 2023-02-28 | 에이씨 이뮨 에스에이 | Nlrp3 인플라마좀 경로를 조절하는 디하이드로옥사졸 및 티오우레아 또는 우레아 유도체 |
| CN114516878B (zh) * | 2020-11-20 | 2024-02-02 | 上海拓界生物医药科技有限公司 | 三环化合物及其医药用途 |
| CN114539256B (zh) * | 2020-11-20 | 2024-02-02 | 上海拓界生物医药科技有限公司 | 三环化合物及其医药用途 |
| CN115894478B (zh) * | 2021-09-30 | 2025-04-04 | 杭州民生药物研究院有限公司 | 一种新型吡啶并吡唑类杂环化合物及其应用 |
| EP4452972A1 (en) | 2021-12-22 | 2024-10-30 | AC Immune SA | Dihydro-oxazol derivative compounds |
| TW202333678A (zh) * | 2021-12-22 | 2023-09-01 | 大陸商瑞石生物醫藥有限公司 | 一種磺醯脲類化合物 |
| WO2023211929A1 (en) * | 2022-04-25 | 2023-11-02 | Vanderbilt University | Probes and methods for targeted visualization of nlrp3 inflammasomes |
| CN117247393A (zh) * | 2022-06-17 | 2023-12-19 | 成都百裕制药股份有限公司 | 酰胺衍生物及其制备方法和在医药上的应用 |
| KR20250036233A (ko) | 2022-07-14 | 2025-03-13 | 에이씨 이뮨 에스에이 | Nlrp3 인플라마좀 경로의 조절제로서의 피롤로트리아진 및 이미다조트리아진 유도체 |
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| GB201819083D0 (en) | 2018-11-23 | 2019-01-09 | Inflazome Ltd | Novel compounds |
-
2018
- 2018-01-22 UA UAA201907805A patent/UA126675C2/uk unknown
- 2018-01-22 BR BR112019014549-4A patent/BR112019014549A2/pt not_active IP Right Cessation
- 2018-01-22 CA CA3047336A patent/CA3047336A1/en active Pending
- 2018-01-22 MA MA047308A patent/MA47308A/fr unknown
- 2018-01-22 EP EP18704341.9A patent/EP3571187B1/en active Active
- 2018-01-22 SG SG11201906373VA patent/SG11201906373VA/en unknown
- 2018-01-22 TW TW107102246A patent/TW201837021A/zh unknown
- 2018-01-22 EP EP20212018.4A patent/EP3851434A1/en not_active Withdrawn
- 2018-01-22 AU AU2018210525A patent/AU2018210525B2/en not_active Ceased
- 2018-01-22 MX MX2019008592A patent/MX2019008592A/es unknown
- 2018-01-22 KR KR1020197024262A patent/KR20190111068A/ko not_active Abandoned
- 2018-01-22 CN CN201880014694.0A patent/CN110366549A/zh active Pending
- 2018-01-22 PE PE2019001474A patent/PE20191615A1/es unknown
- 2018-01-22 WO PCT/US2018/014728 patent/WO2018136890A1/en not_active Ceased
- 2018-01-22 MA MA055695A patent/MA55695A/fr unknown
- 2018-01-22 JP JP2019539814A patent/JP7163293B2/ja active Active
- 2018-01-22 MY MYPI2019004010A patent/MY197636A/en unknown
- 2018-01-22 CR CR20190356A patent/CR20190356A/es unknown
-
2019
- 2019-07-09 PH PH12019501611A patent/PH12019501611A1/en unknown
- 2019-07-10 IL IL267961A patent/IL267961B2/en unknown
- 2019-07-15 CL CL2019001988A patent/CL2019001988A1/es unknown
- 2019-07-16 US US16/513,621 patent/US11040985B2/en active Active
- 2019-08-21 CO CONC2019/0009036A patent/CO2019009036A2/es unknown
-
2021
- 2021-01-25 US US17/157,749 patent/US20210395268A1/en not_active Abandoned
-
2022
- 2022-03-03 US US17/686,183 patent/US11702428B2/en active Active
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