MA50063A - Composés, compositions et procédés - Google Patents
Composés, compositions et procédésInfo
- Publication number
- MA50063A MA50063A MA050063A MA50063A MA50063A MA 50063 A MA50063 A MA 50063A MA 050063 A MA050063 A MA 050063A MA 50063 A MA50063 A MA 50063A MA 50063 A MA50063 A MA 50063A
- Authority
- MA
- Morocco
- Prior art keywords
- compositions
- compounds
- processes
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762553750P | 2017-09-01 | 2017-09-01 | |
| US201762609267P | 2017-12-21 | 2017-12-21 | |
| US201862634721P | 2018-02-23 | 2018-02-23 | |
| US201862697281P | 2018-07-12 | 2018-07-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA50063A true MA50063A (fr) | 2021-04-28 |
Family
ID=65526108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA050063A MA50063A (fr) | 2017-09-01 | 2018-08-31 | Composés, compositions et procédés |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US12139478B2 (enExample) |
| EP (2) | EP3676297B1 (enExample) |
| JP (3) | JP7382308B2 (enExample) |
| CN (1) | CN111201245B (enExample) |
| CA (1) | CA3072057A1 (enExample) |
| DK (1) | DK3676297T3 (enExample) |
| ES (1) | ES2952994T3 (enExample) |
| FI (1) | FI3676297T3 (enExample) |
| HU (1) | HUE062446T2 (enExample) |
| MA (1) | MA50063A (enExample) |
| PL (1) | PL3676297T3 (enExample) |
| PT (1) | PT3676297T (enExample) |
| SI (1) | SI3676297T1 (enExample) |
| TW (1) | TW201920129A (enExample) |
| WO (1) | WO2019046779A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL301709B2 (en) | 2017-08-09 | 2025-07-01 | Denali Therapeutics Inc | Compounds, compositions and methods |
| EP3676297B1 (en) | 2017-09-01 | 2023-05-17 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| AU2018358160B2 (en) | 2017-11-02 | 2023-03-16 | Abbvie Inc. | Modulators of the integrated stress pathway |
| CA3085132A1 (en) | 2017-12-13 | 2019-06-20 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| US11166942B2 (en) | 2018-06-05 | 2021-11-09 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| TWI771621B (zh) | 2018-10-11 | 2022-07-21 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| BR112021015639A2 (pt) | 2019-02-13 | 2021-10-05 | Denali Therapeutics Inc. | Compostos, composições e métodos |
| EP3924341A4 (en) | 2019-02-13 | 2022-11-02 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| CN114008041A (zh) * | 2019-04-23 | 2022-02-01 | 埃沃特克国际有限责任公司 | 整合应激反应路径的调节剂 |
| CN113993850B (zh) * | 2019-04-23 | 2024-03-29 | 埃沃特克国际有限责任公司 | 整合应激反应途径的调节剂 |
| JP7755488B2 (ja) * | 2019-04-30 | 2025-10-16 | カリコ ライフ サイエンシーズ エルエルシー | 統合的ストレス経路の調節剤としての置換シクロアルキル |
| CA3142748A1 (en) | 2019-06-12 | 2020-12-17 | Praxis Biotech LLC | Modulators of integrated stress response pathway |
| MX2022009243A (es) | 2020-01-28 | 2022-08-16 | Evotec Int Gmbh | Moduladores de la via de respuesta integrada al estres. |
| MX2022011143A (es) * | 2020-03-11 | 2022-10-13 | Evotec Int Gmbh | Moduladores de la via de respuesta integrada al estres. |
| EP4232447A1 (en) | 2020-10-22 | 2023-08-30 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| CA3195290A1 (en) | 2020-10-22 | 2022-04-28 | Holly Victoria Atton | Modulators of the integrated stress response pathway |
| CN116761803A (zh) * | 2020-10-22 | 2023-09-15 | 埃沃特克国际有限责任公司 | 整合应激反应途径的调节剂 |
| US20230382905A1 (en) | 2020-10-22 | 2023-11-30 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| WO2022094244A1 (en) * | 2020-10-30 | 2022-05-05 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| CN116768877A (zh) * | 2022-05-30 | 2023-09-19 | 中国药科大学 | Isr抑制剂及其制备方法和应用 |
| TW202440081A (zh) * | 2023-03-14 | 2024-10-16 | 美商人福醫藥美國公司 | σ-1受體拮抗劑及其應用 |
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| IL301709B2 (en) | 2017-08-09 | 2025-07-01 | Denali Therapeutics Inc | Compounds, compositions and methods |
| EP3676297B1 (en) | 2017-09-01 | 2023-05-17 | Denali Therapeutics Inc. | Compounds, compositions and methods |
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| US20200361881A1 (en) | 2017-11-02 | 2020-11-19 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| UY37956A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
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| US20230192712A1 (en) | 2017-11-02 | 2023-06-22 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
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| TWI771621B (zh) | 2018-10-11 | 2022-07-21 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| BR112021015639A2 (pt) | 2019-02-13 | 2021-10-05 | Denali Therapeutics Inc. | Compostos, composições e métodos |
| EP3924341A4 (en) | 2019-02-13 | 2022-11-02 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| US20220177456A1 (en) | 2019-03-06 | 2022-06-09 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| CN113993850B (zh) | 2019-04-23 | 2024-03-29 | 埃沃特克国际有限责任公司 | 整合应激反应途径的调节剂 |
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| JP7755488B2 (ja) | 2019-04-30 | 2025-10-16 | カリコ ライフ サイエンシーズ エルエルシー | 統合的ストレス経路の調節剤としての置換シクロアルキル |
| MX2022009243A (es) | 2020-01-28 | 2022-08-16 | Evotec Int Gmbh | Moduladores de la via de respuesta integrada al estres. |
| CR20230254A (es) | 2020-12-18 | 2023-07-26 | Denali Therapeutics Inc | Formas sólidas de un compuesto |
| JP2025523444A (ja) | 2022-06-23 | 2025-07-23 | デナリ セラピューティクス インコーポレイテッド | 真核生物型開始因子２ｂのモジュレーターの調製プロセス |
-
2018
- 2018-08-31 EP EP18850713.1A patent/EP3676297B1/en active Active
- 2018-08-31 SI SI201830964T patent/SI3676297T1/sl unknown
- 2018-08-31 PT PT188507131T patent/PT3676297T/pt unknown
- 2018-08-31 PL PL18850713.1T patent/PL3676297T3/pl unknown
- 2018-08-31 US US16/643,168 patent/US12139478B2/en active Active
- 2018-08-31 DK DK18850713.1T patent/DK3676297T3/da active
- 2018-08-31 EP EP23173466.6A patent/EP4248965A3/en active Pending
- 2018-08-31 HU HUE18850713A patent/HUE062446T2/hu unknown
- 2018-08-31 WO PCT/US2018/049197 patent/WO2019046779A1/en not_active Ceased
- 2018-08-31 ES ES18850713T patent/ES2952994T3/es active Active
- 2018-08-31 MA MA050063A patent/MA50063A/fr unknown
- 2018-08-31 CA CA3072057A patent/CA3072057A1/en active Pending
- 2018-08-31 TW TW107130678A patent/TW201920129A/zh unknown
- 2018-08-31 CN CN201880063335.4A patent/CN111201245B/zh active Active
- 2018-08-31 FI FIEP18850713.1T patent/FI3676297T3/fi active
- 2018-08-31 JP JP2020511347A patent/JP7382308B2/ja active Active
-
2023
- 2023-02-28 JP JP2023030214A patent/JP2023060020A/ja active Pending
-
2024
- 2024-04-08 JP JP2024062313A patent/JP2024086819A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HUE062446T2 (hu) | 2023-11-28 |
| WO2019046779A1 (en) | 2019-03-07 |
| EP3676297A4 (en) | 2021-04-28 |
| DK3676297T3 (da) | 2023-08-14 |
| PT3676297T (pt) | 2023-08-29 |
| JP2024086819A (ja) | 2024-06-28 |
| EP3676297B1 (en) | 2023-05-17 |
| US20200331900A1 (en) | 2020-10-22 |
| JP2023060020A (ja) | 2023-04-27 |
| FI3676297T3 (fi) | 2023-08-08 |
| EP3676297A1 (en) | 2020-07-08 |
| JP7382308B2 (ja) | 2023-11-16 |
| CN111201245B (zh) | 2024-04-05 |
| US12139478B2 (en) | 2024-11-12 |
| ES2952994T3 (es) | 2023-11-07 |
| JP2020532506A (ja) | 2020-11-12 |
| EP4248965A3 (en) | 2023-11-22 |
| CN111201245A (zh) | 2020-05-26 |
| EP4248965A2 (en) | 2023-09-27 |
| TW201920129A (zh) | 2019-06-01 |
| PL3676297T3 (pl) | 2023-12-11 |
| CA3072057A1 (en) | 2019-03-07 |
| SI3676297T1 (sl) | 2023-12-29 |
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