HUE062446T2 - Vegyületek, készítmények és eljárások - Google Patents

Vegyületek, készítmények és eljárások

Info

Publication number
HUE062446T2
HUE062446T2 HUE18850713A HUE18850713A HUE062446T2 HU E062446 T2 HUE062446 T2 HU E062446T2 HU E18850713 A HUE18850713 A HU E18850713A HU E18850713 A HUE18850713 A HU E18850713A HU E062446 T2 HUE062446 T2 HU E062446T2
Authority
HU
Hungary
Prior art keywords
compositions
compounds
methods
Prior art date
Application number
HUE18850713A
Other languages
English (en)
Inventor
Robert A Craig
Original Assignee
Denali Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Denali Therapeutics Inc filed Critical Denali Therapeutics Inc
Publication of HUE062446T2 publication Critical patent/HUE062446T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HUE18850713A 2017-09-01 2018-08-31 Vegyületek, készítmények és eljárások HUE062446T2 (hu)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762553750P 2017-09-01 2017-09-01
US201762609267P 2017-12-21 2017-12-21
US201862634721P 2018-02-23 2018-02-23
US201862697281P 2018-07-12 2018-07-12

Publications (1)

Publication Number Publication Date
HUE062446T2 true HUE062446T2 (hu) 2023-11-28

Family

ID=65526108

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE18850713A HUE062446T2 (hu) 2017-09-01 2018-08-31 Vegyületek, készítmények és eljárások

Country Status (15)

Country Link
US (1) US20200331900A1 (hu)
EP (2) EP3676297B1 (hu)
JP (2) JP7382308B2 (hu)
CN (1) CN111201245B (hu)
CA (1) CA3072057A1 (hu)
DK (1) DK3676297T3 (hu)
ES (1) ES2952994T3 (hu)
FI (1) FI3676297T3 (hu)
HU (1) HUE062446T2 (hu)
MA (1) MA50063A (hu)
PL (1) PL3676297T3 (hu)
PT (1) PT3676297T (hu)
SI (1) SI3676297T1 (hu)
TW (1) TW201920129A (hu)
WO (1) WO2019046779A1 (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL272089B2 (en) 2017-08-09 2023-09-01 Denali Therapeutics Inc Compounds, preparations and methods
MX2020004557A (es) 2017-11-02 2020-10-05 Calico Life Sciences Llc Moduladores de la vía de estrés integrada.
CA3085132A1 (en) 2017-12-13 2019-06-20 Praxis Biotech LLC Inhibitors of integrated stress response pathway
EP3801522A4 (en) 2018-06-05 2022-06-01 Praxis Biotech LLC INTEGRATED STRESS RESPONSE PATHWAY INHIBITORS
TWI771621B (zh) 2018-10-11 2022-07-21 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
MA54953A (fr) 2019-02-13 2021-12-22 Denali Therapeutics Inc Composés, compositions et procédés
MX2021012904A (es) 2019-04-23 2022-01-18 Evotec Int Gmbh Moduladores de la via de respuesta al estres integrada.
US20220227747A1 (en) * 2019-04-23 2022-07-21 Evotec International Gmbh Modulators of the integrated stress response pathway
CN114206848A (zh) * 2019-04-30 2022-03-18 卡里科生命科学有限责任公司 作为整合应激通路的调节剂的被取代的环烷基化合物
JP2022536663A (ja) 2019-06-12 2022-08-18 プラクシス バイオテック エルエルシー 統合的ストレス応答経路のモジュレーター
IL294805A (en) 2020-01-28 2022-09-01 Evotec Int Gmbh Integrated stress response pathway modulators
MX2022011143A (es) * 2020-03-11 2022-10-13 Evotec Int Gmbh Moduladores de la via de respuesta integrada al estres.
MX2023004626A (es) 2020-10-22 2023-05-23 Evotec Int Gmbh Moduladores de la via de respuesta integrada al estres.
AU2021363616A1 (en) 2020-10-22 2023-06-22 Evotec International Gmbh Modulators of the integrated stress response pathway
US20230382905A1 (en) 2020-10-22 2023-11-30 Evotec International Gmbh Modulators of the integrated stress response pathway
MX2023004870A (es) * 2020-10-30 2023-05-11 Calico Life Sciences Llc Moduladores de la via integrada del estres.
CN116768877A (zh) * 2022-05-30 2023-09-19 中国药科大学 Isr抑制剂及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006032466A2 (en) * 2004-09-24 2006-03-30 Actelion Pharmaceuticals Ltd New bicyclic antibiotics
JP2008542249A (ja) * 2005-05-24 2008-11-27 アストラゼネカ アクチボラグ 抗細菌活性を持つアミノピペリジンキノリン及びそのアザ等立体類似体
BRPI0812942B1 (pt) * 2007-06-15 2018-11-21 Actelion Pharmaceuticals Ltd composto derivado de 3-amino-6 - (1-amino-etil) - tetra-hidropirano, composição farmacêutica e uso de referido composto.
NZ593891A (en) * 2008-12-12 2013-05-31 Actelion Pharmaceuticals Ltd 5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives
SG10201601802YA (en) 2011-03-10 2016-04-28 Daiichi Sankyo Co Ltd Dispiropyrrolidine derivatives
TW201718557A (zh) * 2015-10-08 2017-06-01 歌林達有限公司 經吡唑基取代之四氫吡喃基碸
WO2019054430A1 (ja) 2017-09-14 2019-03-21 第一三共株式会社 芳香族複素環を有するアミド化合物

Also Published As

Publication number Publication date
MA50063A (fr) 2021-04-28
PT3676297T (pt) 2023-08-29
EP4248965A2 (en) 2023-09-27
FI3676297T3 (fi) 2023-08-08
EP3676297A1 (en) 2020-07-08
CN111201245A (zh) 2020-05-26
EP3676297B1 (en) 2023-05-17
CN111201245B (zh) 2024-04-05
DK3676297T3 (da) 2023-08-14
WO2019046779A1 (en) 2019-03-07
TW201920129A (zh) 2019-06-01
PL3676297T3 (pl) 2023-12-11
US20200331900A1 (en) 2020-10-22
ES2952994T3 (es) 2023-11-07
JP7382308B2 (ja) 2023-11-16
EP3676297A4 (en) 2021-04-28
EP4248965A3 (en) 2023-11-22
JP2020532506A (ja) 2020-11-12
SI3676297T1 (sl) 2023-12-29
JP2023060020A (ja) 2023-04-27
CA3072057A1 (en) 2019-03-07

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