SI3676297T1 - Spojine, sestavki in postopki - Google Patents

Spojine, sestavki in postopki

Info

Publication number
SI3676297T1
SI3676297T1 SI201830964T SI201830964T SI3676297T1 SI 3676297 T1 SI3676297 T1 SI 3676297T1 SI 201830964 T SI201830964 T SI 201830964T SI 201830964 T SI201830964 T SI 201830964T SI 3676297 T1 SI3676297 T1 SI 3676297T1
Authority
SI
Slovenia
Prior art keywords
compositions
compounds
methods
Prior art date
Application number
SI201830964T
Other languages
English (en)
Inventor
Robert A. Ii Craig
Anthony A. Estrada
Jianwen A. Feng
Katrina W. Lexa
Maksim Osipov
Zachary K. Sweeney
Vicente Fidalgo Javier De
Original Assignee
Denali Therapeutics Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Denali Therapeutics Inc. filed Critical Denali Therapeutics Inc.
Publication of SI3676297T1 publication Critical patent/SI3676297T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SI201830964T 2017-09-01 2018-08-31 Spojine, sestavki in postopki SI3676297T1 (sl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201762553750P 2017-09-01 2017-09-01
US201762609267P 2017-12-21 2017-12-21
US201862634721P 2018-02-23 2018-02-23
US201862697281P 2018-07-12 2018-07-12
PCT/US2018/049197 WO2019046779A1 (en) 2017-09-01 2018-08-31 COMPOUNDS, COMPOSITIONS AND METHODS
EP18850713.1A EP3676297B1 (en) 2017-09-01 2018-08-31 Compounds, compositions and methods

Publications (1)

Publication Number Publication Date
SI3676297T1 true SI3676297T1 (sl) 2023-12-29

Family

ID=65526108

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201830964T SI3676297T1 (sl) 2017-09-01 2018-08-31 Spojine, sestavki in postopki

Country Status (15)

Country Link
US (1) US20200331900A1 (sl)
EP (2) EP3676297B1 (sl)
JP (2) JP7382308B2 (sl)
CN (1) CN111201245B (sl)
CA (1) CA3072057A1 (sl)
DK (1) DK3676297T3 (sl)
ES (1) ES2952994T3 (sl)
FI (1) FI3676297T3 (sl)
HU (1) HUE062446T2 (sl)
MA (1) MA50063A (sl)
PL (1) PL3676297T3 (sl)
PT (1) PT3676297T (sl)
SI (1) SI3676297T1 (sl)
TW (1) TW201920129A (sl)
WO (1) WO2019046779A1 (sl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL301709A (en) 2017-08-09 2023-05-01 Denali Therapeutics Inc Compounds, preparations and methods
BR112020008834A2 (pt) 2017-11-02 2020-12-22 Calico Life Sciences Llc Moduladores da via de estresse integrada
JP2021508336A (ja) 2017-12-13 2021-03-04 プラクシス バイオテック エルエルシー 統合的ストレス応答経路の阻害剤
EP3801522A4 (en) 2018-06-05 2022-06-01 Praxis Biotech LLC INTEGRATED STRESS RESPONSE PATHWAY INHIBITORS
TWI832295B (zh) 2018-10-11 2024-02-11 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
CR20210426A (es) 2019-02-13 2021-09-30 Denali Therapeutics Inc Compuestos, composiciones y métodos
EP3959198A1 (en) 2019-04-23 2022-03-02 Evotec International GmbH Modulators of the integrated stress response pathway
BR112021020106A2 (pt) * 2019-04-23 2021-12-07 Evotec Int Gmbh Moduladores da via de resposta ao estresse inte-grado
CN114206848A (zh) * 2019-04-30 2022-03-18 卡里科生命科学有限责任公司 作为整合应激通路的调节剂的被取代的环烷基化合物
EP3982965A4 (en) 2019-06-12 2023-01-25 Praxis Biotech LLC INTEGRATED STRESS RESPONSE PATHWAY MODULATORS
US20230125481A1 (en) 2020-01-28 2023-04-27 Evotec International Gmbh Modulators of the integrated stress response pathway
EP4117780A1 (en) 2020-03-11 2023-01-18 Evotec International GmbH Modulators of the integrated stress response pathway
US20230391763A1 (en) 2020-10-22 2023-12-07 Evotec International Gmbh Modulators of the integrated stress response pathway
KR20230110511A (ko) 2020-10-22 2023-07-24 에보텍 인터내셔널 게엠베하 통합 스트레스 반응 경로의 조절제
CA3195293A1 (en) 2020-10-22 2022-04-28 Holly Victoria Atton Modulators of the integrated stress response pathway
MX2023004870A (es) * 2020-10-30 2023-05-11 Calico Life Sciences Llc Moduladores de la via integrada del estres.
CN116768877A (zh) * 2022-05-30 2023-09-19 中国药科大学 Isr抑制剂及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006032466A2 (en) * 2004-09-24 2006-03-30 Actelion Pharmaceuticals Ltd New bicyclic antibiotics
US20090131444A1 (en) * 2005-05-24 2009-05-21 Astrazeneca Ab Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity
MX2009013254A (es) * 2007-06-15 2010-01-25 Actelion Pharmaceuticals Ltd Derivados 3-amino-6(1-amino-etil)-tetrahidropirano.
SI2376497T1 (sl) * 2008-12-12 2014-01-31 Actelion Pharmaceuticals Ltd. Derivati 5-amino-2-(1-hidroksi-etil)-tetrahidropirana
WO2012121361A1 (ja) * 2011-03-10 2012-09-13 第一三共株式会社 ジスピロピロリジン誘導体
TW201718557A (zh) * 2015-10-08 2017-06-01 歌林達有限公司 經吡唑基取代之四氫吡喃基碸
WO2019054430A1 (ja) * 2017-09-14 2019-03-21 第一三共株式会社 芳香族複素環を有するアミド化合物

Also Published As

Publication number Publication date
EP4248965A3 (en) 2023-11-22
DK3676297T3 (da) 2023-08-14
EP4248965A2 (en) 2023-09-27
EP3676297A4 (en) 2021-04-28
US20200331900A1 (en) 2020-10-22
CN111201245A (zh) 2020-05-26
EP3676297B1 (en) 2023-05-17
PT3676297T (pt) 2023-08-29
JP7382308B2 (ja) 2023-11-16
HUE062446T2 (hu) 2023-11-28
FI3676297T3 (fi) 2023-08-08
JP2020532506A (ja) 2020-11-12
CN111201245B (zh) 2024-04-05
WO2019046779A1 (en) 2019-03-07
ES2952994T3 (es) 2023-11-07
JP2023060020A (ja) 2023-04-27
EP3676297A1 (en) 2020-07-08
PL3676297T3 (pl) 2023-12-11
CA3072057A1 (en) 2019-03-07
MA50063A (fr) 2021-04-28
TW201920129A (zh) 2019-06-01

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