PL3676297T3 - Związki, kompozycje i sposoby - Google Patents

Związki, kompozycje i sposoby

Info

Publication number
PL3676297T3
PL3676297T3 PL18850713.1T PL18850713T PL3676297T3 PL 3676297 T3 PL3676297 T3 PL 3676297T3 PL 18850713 T PL18850713 T PL 18850713T PL 3676297 T3 PL3676297 T3 PL 3676297T3
Authority
PL
Poland
Prior art keywords
compositions
compounds
methods
Prior art date
Application number
PL18850713.1T
Other languages
English (en)
Inventor
Robert A. II CRAIG
Anthony A. ESTRADA
Jianwen A. FENG
Katrina W. Lexa
Maksim OSIPOV
Zachary K. Sweeney
Javier De Vicente Fidalgo
Original Assignee
Denali Therapeutics Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Denali Therapeutics Inc. filed Critical Denali Therapeutics Inc.
Publication of PL3676297T3 publication Critical patent/PL3676297T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
PL18850713.1T 2017-09-01 2018-08-31 Związki, kompozycje i sposoby PL3676297T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762553750P 2017-09-01 2017-09-01
US201762609267P 2017-12-21 2017-12-21
US201862634721P 2018-02-23 2018-02-23
US201862697281P 2018-07-12 2018-07-12
PCT/US2018/049197 WO2019046779A1 (en) 2017-09-01 2018-08-31 COMPOUNDS, COMPOSITIONS AND METHODS

Publications (1)

Publication Number Publication Date
PL3676297T3 true PL3676297T3 (pl) 2023-12-11

Family

ID=65526108

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18850713.1T PL3676297T3 (pl) 2017-09-01 2018-08-31 Związki, kompozycje i sposoby

Country Status (15)

Country Link
US (1) US20200331900A1 (pl)
EP (2) EP4248965A3 (pl)
JP (3) JP7382308B2 (pl)
CN (1) CN111201245B (pl)
CA (1) CA3072057A1 (pl)
DK (1) DK3676297T3 (pl)
ES (1) ES2952994T3 (pl)
FI (1) FI3676297T3 (pl)
HU (1) HUE062446T2 (pl)
MA (1) MA50063A (pl)
PL (1) PL3676297T3 (pl)
PT (1) PT3676297T (pl)
SI (1) SI3676297T1 (pl)
TW (1) TW201920129A (pl)
WO (1) WO2019046779A1 (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020530446A (ja) 2017-08-09 2020-10-22 デナリ セラピューティクス インコーポレイテッドDenali Therapeutics Inc. 化合物、組成物、及び、方法
JP2021501785A (ja) 2017-11-02 2021-01-21 カリコ ライフ サイエンシーズ エルエルシー 統合的ストレス経路の調節剤
JP2021508336A (ja) 2017-12-13 2021-03-04 プラクシス バイオテック エルエルシー 統合的ストレス応答経路の阻害剤
BR112020023115A2 (pt) 2018-06-05 2021-02-02 Praxis Biotech LLC inibidores da via integrada de resposta a tensão
TWI771621B (zh) 2018-10-11 2022-07-21 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
TW202045164A (zh) 2019-02-13 2020-12-16 美商戴納立製藥公司 化合物、組合物及方法
AU2020262153A1 (en) * 2019-04-23 2021-11-11 Evotec International Gmbh Modulators of the integrated stress response pathway
US20220227747A1 (en) 2019-04-23 2022-07-21 Evotec International Gmbh Modulators of the integrated stress response pathway
AU2020264485A1 (en) * 2019-04-30 2021-12-02 Abbvie Inc. Substituted cycloalkyls as modulators of the integrated stress pathway
CN114466654A (zh) 2019-06-12 2022-05-10 普拉西斯生物技术有限责任公司 整合应激反应通路调节剂
JP2023511616A (ja) 2020-01-28 2023-03-20 エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 統合的ストレス応答経路の調節因子
CA3165813A1 (en) * 2020-03-11 2021-09-16 Holly Victoria Atton Modulators of the integrated stress response pathway
EP4232153A1 (en) 2020-10-22 2023-08-30 Evotec International GmbH Modulators of the integrated stress response pathway
JP2023546226A (ja) 2020-10-22 2023-11-01 エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 統合ストレス応答経路のモジュレーター
KR20230110509A (ko) 2020-10-22 2023-07-24 에보텍 인터내셔널 게엠베하 통합 스트레스 반응 경로의 조절제
WO2022094244A1 (en) * 2020-10-30 2022-05-05 Calico Life Sciences Llc Modulators of the integrated stress pathway
CN116768877A (zh) * 2022-05-30 2023-09-19 中国药科大学 Isr抑制剂及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2580621A1 (en) * 2004-09-24 2006-03-30 Actelion Pharmaceuticals Ltd New bicyclic antibiotics
US20090131444A1 (en) * 2005-05-24 2009-05-21 Astrazeneca Ab Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity
MX2009013254A (es) * 2007-06-15 2010-01-25 Actelion Pharmaceuticals Ltd Derivados 3-amino-6(1-amino-etil)-tetrahidropirano.
JP4955835B2 (ja) * 2008-12-12 2012-06-20 アクテリオン ファーマシューティカルズ リミテッド 5−アミノ−2−(1−ヒドロキシ−エチル)−テトラヒドロピラン誘導体
CA2829188C (en) * 2011-03-10 2016-10-18 Daiichi Sankyo Company, Limited Dispiropyrrolidine derivatives
TW201718557A (zh) * 2015-10-08 2017-06-01 歌林達有限公司 經吡唑基取代之四氫吡喃基碸
WO2019054430A1 (ja) * 2017-09-14 2019-03-21 第一三共株式会社 芳香族複素環を有するアミド化合物

Also Published As

Publication number Publication date
TW201920129A (zh) 2019-06-01
FI3676297T3 (fi) 2023-08-08
WO2019046779A1 (en) 2019-03-07
PT3676297T (pt) 2023-08-29
CN111201245B (zh) 2024-04-05
EP4248965A2 (en) 2023-09-27
EP3676297A4 (en) 2021-04-28
EP4248965A3 (en) 2023-11-22
US20200331900A1 (en) 2020-10-22
CN111201245A (zh) 2020-05-26
ES2952994T3 (es) 2023-11-07
SI3676297T1 (sl) 2023-12-29
JP2020532506A (ja) 2020-11-12
EP3676297B1 (en) 2023-05-17
JP2024086819A (ja) 2024-06-28
MA50063A (fr) 2021-04-28
JP2023060020A (ja) 2023-04-27
HUE062446T2 (hu) 2023-11-28
JP7382308B2 (ja) 2023-11-16
DK3676297T3 (da) 2023-08-14
CA3072057A1 (en) 2019-03-07
EP3676297A1 (en) 2020-07-08

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