SI3676297T1 - Spojine, sestavki in postopki - Google Patents
Spojine, sestavki in postopkiInfo
- Publication number
- SI3676297T1 SI3676297T1 SI201830964T SI201830964T SI3676297T1 SI 3676297 T1 SI3676297 T1 SI 3676297T1 SI 201830964 T SI201830964 T SI 201830964T SI 201830964 T SI201830964 T SI 201830964T SI 3676297 T1 SI3676297 T1 SI 3676297T1
- Authority
- SI
- Slovenia
- Prior art keywords
- compositions
- compounds
- methods
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762553750P | 2017-09-01 | 2017-09-01 | |
| US201762609267P | 2017-12-21 | 2017-12-21 | |
| US201862634721P | 2018-02-23 | 2018-02-23 | |
| US201862697281P | 2018-07-12 | 2018-07-12 | |
| EP18850713.1A EP3676297B1 (en) | 2017-09-01 | 2018-08-31 | Compounds, compositions and methods |
| PCT/US2018/049197 WO2019046779A1 (en) | 2017-09-01 | 2018-08-31 | COMPOUNDS, COMPOSITIONS AND METHODS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3676297T1 true SI3676297T1 (sl) | 2023-12-29 |
Family
ID=65526108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201830964T SI3676297T1 (sl) | 2017-09-01 | 2018-08-31 | Spojine, sestavki in postopki |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US12139478B2 (enExample) |
| EP (2) | EP3676297B1 (enExample) |
| JP (3) | JP7382308B2 (enExample) |
| CN (1) | CN111201245B (enExample) |
| CA (1) | CA3072057A1 (enExample) |
| DK (1) | DK3676297T3 (enExample) |
| ES (1) | ES2952994T3 (enExample) |
| FI (1) | FI3676297T3 (enExample) |
| HU (1) | HUE062446T2 (enExample) |
| MA (1) | MA50063A (enExample) |
| PL (1) | PL3676297T3 (enExample) |
| PT (1) | PT3676297T (enExample) |
| SI (1) | SI3676297T1 (enExample) |
| TW (1) | TW201920129A (enExample) |
| WO (1) | WO2019046779A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111094233B (zh) | 2017-08-09 | 2024-03-15 | 戴纳立制药公司 | 化合物、组合物及方法 |
| PT3676297T (pt) | 2017-09-01 | 2023-08-29 | Denali Therapeutics Inc | Compostos, composições e métodos |
| JP2021501785A (ja) | 2017-11-02 | 2021-01-21 | カリコ ライフ サイエンシーズ エルエルシー | 統合的ストレス経路の調節剤 |
| RU2020122711A (ru) | 2017-12-13 | 2022-01-17 | ПРАКСИС БАЙОТЕК ЭлЭлСи | Ингибиторы пути интегрированной реакции на стресс |
| SG11202011014VA (en) | 2018-06-05 | 2020-12-30 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| TWI832295B (zh) | 2018-10-11 | 2024-02-11 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| MA54959A (fr) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| CA3129609A1 (en) | 2019-02-13 | 2020-08-20 | Denali Therapeutics Inc. | Eukaryotic initiation factor 2b modulators |
| AU2020261234A1 (en) * | 2019-04-23 | 2021-11-11 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| EA202192900A1 (ru) * | 2019-04-23 | 2022-03-18 | Эвотек Интернешнл Гмбх | Модуляторы пути интегрированной реакции на стресс |
| PH12021552759A1 (en) * | 2019-04-30 | 2022-07-04 | Abbvie Inc | Substituted cycloalkyls as modulators of the integrated stress pathway |
| CA3142748A1 (en) | 2019-06-12 | 2020-12-17 | Praxis Biotech LLC | Modulators of integrated stress response pathway |
| KR20220133252A (ko) | 2020-01-28 | 2022-10-04 | 에보텍 인터내셔널 게엠베하 | 통합 스트레스 반응 경로의 조절자 |
| JP2023517944A (ja) * | 2020-03-11 | 2023-04-27 | エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 統合的ストレス応答経路の調節因子 |
| US20230391763A1 (en) * | 2020-10-22 | 2023-12-07 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| AU2021366303A1 (en) | 2020-10-22 | 2023-06-22 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| CN116761803A (zh) * | 2020-10-22 | 2023-09-15 | 埃沃特克国际有限责任公司 | 整合应激反应途径的调节剂 |
| CA3195290A1 (en) | 2020-10-22 | 2022-04-28 | Holly Victoria Atton | Modulators of the integrated stress response pathway |
| EP4237413A1 (en) * | 2020-10-30 | 2023-09-06 | Calico Life Sciences LLC | Modulators of the integrated stress pathway |
| CN116768877A (zh) * | 2022-05-30 | 2023-09-19 | 中国药科大学 | Isr抑制剂及其制备方法和应用 |
| TW202440081A (zh) * | 2023-03-14 | 2024-10-16 | 美商人福醫藥美國公司 | σ-1受體拮抗劑及其應用 |
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| CN111094233B (zh) | 2017-08-09 | 2024-03-15 | 戴纳立制药公司 | 化合物、组合物及方法 |
| PT3676297T (pt) | 2017-09-01 | 2023-08-29 | Denali Therapeutics Inc | Compostos, composições e métodos |
| WO2019054430A1 (ja) | 2017-09-14 | 2019-03-21 | 第一三共株式会社 | 芳香族複素環を有するアミド化合物 |
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| JP2021501785A (ja) | 2017-11-02 | 2021-01-21 | カリコ ライフ サイエンシーズ エルエルシー | 統合的ストレス経路の調節剤 |
| UY37956A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| AU2018360847B2 (en) | 2017-11-02 | 2023-07-27 | Abbvie Inc. | Modulators of the integrated stress pathway |
| US20200347033A1 (en) | 2017-11-02 | 2020-11-05 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| JP7307057B2 (ja) | 2017-11-02 | 2023-07-11 | カリコ ライフ サイエンシーズ エルエルシー | 統合的ストレス経路の調節剤 |
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| KR20200092332A (ko) | 2017-11-02 | 2020-08-03 | 칼리코 라이프 사이언시스 엘엘씨 | 통합된 스트레스 경로의 조절제 |
| RU2020122711A (ru) | 2017-12-13 | 2022-01-17 | ПРАКСИС БАЙОТЕК ЭлЭлСи | Ингибиторы пути интегрированной реакции на стресс |
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| JP2021529814A (ja) | 2018-07-09 | 2021-11-04 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | 化学化合物 |
| WO2020031107A1 (en) | 2018-08-08 | 2020-02-13 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds |
| TWI832295B (zh) | 2018-10-11 | 2024-02-11 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| MA54959A (fr) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| CA3129609A1 (en) | 2019-02-13 | 2020-08-20 | Denali Therapeutics Inc. | Eukaryotic initiation factor 2b modulators |
| US20220177456A1 (en) | 2019-03-06 | 2022-06-09 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| AU2020261234A1 (en) | 2019-04-23 | 2021-11-11 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| PH12021552759A1 (en) | 2019-04-30 | 2022-07-04 | Abbvie Inc | Substituted cycloalkyls as modulators of the integrated stress pathway |
| AU2020266592A1 (en) | 2019-04-30 | 2021-12-02 | Abbvie Inc. | Substituted cyclolakyls as modulators of the integrated stress pathway |
| KR20220133252A (ko) | 2020-01-28 | 2022-10-04 | 에보텍 인터내셔널 게엠베하 | 통합 스트레스 반응 경로의 조절자 |
| CA3205231A1 (en) | 2020-12-18 | 2022-06-23 | Denali Therapeutics Inc. | Solid forms of a compound |
| US20250376432A1 (en) | 2022-06-23 | 2025-12-11 | Denali Therapeutics Inc. | Process for preparing modulators of eukaryotic initiation factor 2b |
-
2018
- 2018-08-31 PT PT188507131T patent/PT3676297T/pt unknown
- 2018-08-31 DK DK18850713.1T patent/DK3676297T3/da active
- 2018-08-31 TW TW107130678A patent/TW201920129A/zh unknown
- 2018-08-31 PL PL18850713.1T patent/PL3676297T3/pl unknown
- 2018-08-31 ES ES18850713T patent/ES2952994T3/es active Active
- 2018-08-31 US US16/643,168 patent/US12139478B2/en active Active
- 2018-08-31 EP EP18850713.1A patent/EP3676297B1/en active Active
- 2018-08-31 MA MA050063A patent/MA50063A/fr unknown
- 2018-08-31 CA CA3072057A patent/CA3072057A1/en active Pending
- 2018-08-31 FI FIEP18850713.1T patent/FI3676297T3/fi active
- 2018-08-31 JP JP2020511347A patent/JP7382308B2/ja active Active
- 2018-08-31 CN CN201880063335.4A patent/CN111201245B/zh active Active
- 2018-08-31 WO PCT/US2018/049197 patent/WO2019046779A1/en not_active Ceased
- 2018-08-31 EP EP23173466.6A patent/EP4248965A3/en active Pending
- 2018-08-31 HU HUE18850713A patent/HUE062446T2/hu unknown
- 2018-08-31 SI SI201830964T patent/SI3676297T1/sl unknown
-
2023
- 2023-02-28 JP JP2023030214A patent/JP2023060020A/ja active Pending
-
2024
- 2024-04-08 JP JP2024062313A patent/JP2024086819A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20200331900A1 (en) | 2020-10-22 |
| MA50063A (fr) | 2021-04-28 |
| PT3676297T (pt) | 2023-08-29 |
| TW201920129A (zh) | 2019-06-01 |
| EP3676297A1 (en) | 2020-07-08 |
| PL3676297T3 (pl) | 2023-12-11 |
| CA3072057A1 (en) | 2019-03-07 |
| JP7382308B2 (ja) | 2023-11-16 |
| EP3676297B1 (en) | 2023-05-17 |
| FI3676297T3 (fi) | 2023-08-08 |
| EP4248965A2 (en) | 2023-09-27 |
| HUE062446T2 (hu) | 2023-11-28 |
| CN111201245A (zh) | 2020-05-26 |
| JP2023060020A (ja) | 2023-04-27 |
| JP2020532506A (ja) | 2020-11-12 |
| US12139478B2 (en) | 2024-11-12 |
| DK3676297T3 (da) | 2023-08-14 |
| EP4248965A3 (en) | 2023-11-22 |
| CN111201245B (zh) | 2024-04-05 |
| ES2952994T3 (es) | 2023-11-07 |
| JP2024086819A (ja) | 2024-06-28 |
| EP3676297A4 (en) | 2021-04-28 |
| WO2019046779A1 (en) | 2019-03-07 |
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