MA48861A - Améliorations pharmacocinétiques de chélates bifonctionnels et leurs utilisations - Google Patents

Améliorations pharmacocinétiques de chélates bifonctionnels et leurs utilisations

Info

Publication number
MA48861A
MA48861A MA048861A MA48861A MA48861A MA 48861 A MA48861 A MA 48861A MA 048861 A MA048861 A MA 048861A MA 48861 A MA48861 A MA 48861A MA 48861 A MA48861 A MA 48861A
Authority
MA
Morocco
Prior art keywords
enhancements
pharmacokinetic
bifunctional chelates
chelates
bifunctional
Prior art date
Application number
MA048861A
Other languages
English (en)
French (fr)
Inventor
Eric Steven Burak
Stuart James Mahoney
Ryan Wayne Simms
John Fitzmaurice Valliant
Original Assignee
Fusion Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fusion Pharmaceuticals Inc filed Critical Fusion Pharmaceuticals Inc
Publication of MA48861A publication Critical patent/MA48861A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MA048861A 2017-05-05 2018-05-04 Améliorations pharmacocinétiques de chélates bifonctionnels et leurs utilisations MA48861A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762502260P 2017-05-05 2017-05-05

Publications (1)

Publication Number Publication Date
MA48861A true MA48861A (fr) 2020-04-01

Family

ID=64016761

Family Applications (1)

Application Number Title Priority Date Filing Date
MA048861A MA48861A (fr) 2017-05-05 2018-05-04 Améliorations pharmacocinétiques de chélates bifonctionnels et leurs utilisations

Country Status (15)

Country Link
US (2) US11191854B2 (enExample)
EP (1) EP3619191A4 (enExample)
JP (2) JP7693317B2 (enExample)
KR (1) KR102612882B1 (enExample)
CN (2) CN111263747B (enExample)
AU (3) AU2018261888B2 (enExample)
BR (1) BR112019023246B1 (enExample)
CA (1) CA3062553C (enExample)
CL (1) CL2019003168A1 (enExample)
EA (1) EA201992595A1 (enExample)
IL (1) IL270453B2 (enExample)
MA (1) MA48861A (enExample)
RU (1) RU2019139432A (enExample)
WO (1) WO2018204869A1 (enExample)
ZA (1) ZA201908071B (enExample)

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AU2019287595B2 (en) * 2018-04-27 2024-10-31 University Of Iowa Research Foundation Compositions for chelating metals at low temperatures
MA54401A (fr) * 2018-12-03 2021-10-13 Fusion Pharmaceuticals Inc Polythérapie associant des radioimmunoconjugués et des inhibiteurs de réparation des dommages à l'adn
AU2019435951B2 (en) * 2019-03-20 2025-08-14 Provincial Health Services Authority Chelators and methods of making and using same
EP4087621A4 (en) * 2020-01-10 2024-01-17 Fusion Pharmaceuticals Inc. MACROCYCLIC CHELATES AND USES THEREOF
BR112022013681A2 (pt) * 2020-01-10 2022-11-16 Fusion Pharmaceuticals Inc Imunoterapia sustentada
WO2021195131A1 (en) * 2020-03-23 2021-09-30 Fusion Pharmaceuticals Inc. Fgfr3-targeted radioimmunoconjugates and uses thereof
KR102362962B1 (ko) * 2020-06-12 2022-02-16 (주)미래바이오팜 신규한 화합물 및 이를 함유하는 신경 손상, 신경 질환, 또는 발달 장애에 대한 신경세포의 증식 촉진, 분화, 및/또는 재생을 통한 치료 또는 예방용 약제학적 조성물
WO2022025184A1 (ja) * 2020-07-29 2022-02-03 中外製薬株式会社 非放射性物質で標識した薬剤の薬物動態を測定する方法
WO2022198319A1 (en) * 2021-03-23 2022-09-29 Fusion Pharmaceuticals Inc. Use of a cold fgfr3-targeting molecule and a fgfr3 targeting radioimmunoconjugate for treating cancer
WO2022266499A1 (en) * 2021-06-17 2022-12-22 Mayo Foundation For Medical Education And Research Methods and materials for combining biologics with multiple chelators
WO2023164777A1 (en) * 2022-03-04 2023-09-07 Fusion Pharmaceuticals Inc. Gucy2c-targeted radiopharmaceuticals and use thereof
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EP4637843A2 (en) * 2022-12-21 2025-10-29 Mayo Foundation for Medical Education and Research Methods and materials for combining biologics with multiple chelators

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Also Published As

Publication number Publication date
AU2018261888B2 (en) 2022-06-30
AU2018261888A1 (en) 2019-11-28
AU2024227706A1 (en) 2024-11-21
EA201992595A1 (ru) 2020-04-21
EP3619191A1 (en) 2020-03-11
JP2023090748A (ja) 2023-06-29
IL270453A (enExample) 2020-12-31
IL270453B2 (en) 2025-05-01
BR112019023246A8 (pt) 2021-02-23
CA3062553C (en) 2024-02-06
RU2019139432A (ru) 2021-06-07
BR112019023246B1 (pt) 2023-11-14
KR102612882B1 (ko) 2023-12-11
KR20200006087A (ko) 2020-01-17
IL270453B1 (en) 2025-01-01
CN111263747A (zh) 2020-06-09
BR112019023246A2 (pt) 2020-05-19
CN111263747B (zh) 2023-10-27
AU2022221451A1 (en) 2022-09-22
CA3062553A1 (en) 2018-11-08
NZ759832A (en) 2025-05-30
RU2019139432A3 (enExample) 2021-06-16
ZA201908071B (en) 2023-04-26
US20190030194A1 (en) 2019-01-31
JP2020518673A (ja) 2020-06-25
CL2019003168A1 (es) 2020-08-28
WO2018204869A1 (en) 2018-11-08
US20220054664A1 (en) 2022-02-24
JP7693317B2 (ja) 2025-06-17
US11191854B2 (en) 2021-12-07
EP3619191A4 (en) 2020-12-16
CN117603148A (zh) 2024-02-27

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