CA3062553C - Pharmacokinetic enhancements of bifunctional chelates and uses thereof - Google Patents
Pharmacokinetic enhancements of bifunctional chelates and uses thereof Download PDFInfo
- Publication number
- CA3062553C CA3062553C CA3062553A CA3062553A CA3062553C CA 3062553 C CA3062553 C CA 3062553C CA 3062553 A CA3062553 A CA 3062553A CA 3062553 A CA3062553 A CA 3062553A CA 3062553 C CA3062553 C CA 3062553C
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- acid
- compound
- alkyl
- group
- optionally substituted
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- 238000000034 method Methods 0.000 claims abstract description 55
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- JHALWMSZGCVVEM-UHFFFAOYSA-N 2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid Chemical compound OC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CC1 JHALWMSZGCVVEM-UHFFFAOYSA-N 0.000 claims description 8
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- C07D—HETEROCYCLIC COMPOUNDS
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- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
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- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
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| PCT/US2018/031228 WO2018204869A1 (en) | 2017-05-05 | 2018-05-04 | Pharmacokinetic enhancements of bifunctional chelates and uses thereof |
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| RU2019139432A (ru) | 2017-05-05 | 2021-06-07 | Сентр фор Проуб Девелопмент энд Коммерсиализэйшн | Фармакокинетическая оптимизация бифункциональных хелатов и их применение |
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| AU2019435951B2 (en) * | 2019-03-20 | 2025-08-14 | Provincial Health Services Authority | Chelators and methods of making and using same |
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| BR112019023246A2 (pt) | 2020-05-19 |
| CN111263747B (zh) | 2023-10-27 |
| AU2022221451A1 (en) | 2022-09-22 |
| CA3062553A1 (en) | 2018-11-08 |
| NZ759832A (en) | 2025-05-30 |
| RU2019139432A3 (enExample) | 2021-06-16 |
| ZA201908071B (en) | 2023-04-26 |
| US20190030194A1 (en) | 2019-01-31 |
| JP2020518673A (ja) | 2020-06-25 |
| CL2019003168A1 (es) | 2020-08-28 |
| WO2018204869A1 (en) | 2018-11-08 |
| US20220054664A1 (en) | 2022-02-24 |
| JP7693317B2 (ja) | 2025-06-17 |
| US11191854B2 (en) | 2021-12-07 |
| EP3619191A4 (en) | 2020-12-16 |
| CN117603148A (zh) | 2024-02-27 |
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