MA33280B1 - Preparation solide - Google Patents
Preparation solideInfo
- Publication number
- MA33280B1 MA33280B1 MA34358A MA34358A MA33280B1 MA 33280 B1 MA33280 B1 MA 33280B1 MA 34358 A MA34358 A MA 34358A MA 34358 A MA34358 A MA 34358A MA 33280 B1 MA33280 B1 MA 33280B1
- Authority
- MA
- Morocco
- Prior art keywords
- solid product
- superior
- symbol
- iii
- salt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La présente invention a pour objet une préparation solide comprenant (i) un composé représenté par la formule (I), chaque symbole étant tel que défini dans la description, ou un sel de celui-ci, (ii) un alcool de sucre, et (iii) un antagoniste du calcium, qui est supérieur du point de vue de la propriété de dissolution et de la stabilité.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009111381 | 2009-04-30 | ||
JP2010068625 | 2010-03-24 | ||
PCT/JP2010/057923 WO2010126168A2 (fr) | 2009-04-30 | 2010-04-28 | Préparation solide |
Publications (1)
Publication Number | Publication Date |
---|---|
MA33280B1 true MA33280B1 (fr) | 2012-05-02 |
Family
ID=43032637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA34358A MA33280B1 (fr) | 2009-04-30 | 2010-04-28 | Preparation solide |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP2424501A2 (fr) |
JP (1) | JP5666471B2 (fr) |
KR (1) | KR101797776B1 (fr) |
CN (1) | CN102481248B (fr) |
AU (1) | AU2010242308A1 (fr) |
BR (1) | BRPI1014388A2 (fr) |
CA (1) | CA2760073A1 (fr) |
CL (1) | CL2011002662A1 (fr) |
CO (1) | CO6470841A2 (fr) |
CR (1) | CR20110581A (fr) |
DO (1) | DOP2011000329A (fr) |
EA (1) | EA201171329A1 (fr) |
EC (1) | ECSP11011494A (fr) |
GE (1) | GEP20135940B (fr) |
IL (1) | IL215962A0 (fr) |
MA (1) | MA33280B1 (fr) |
MX (1) | MX2011011011A (fr) |
MY (1) | MY158158A (fr) |
NZ (1) | NZ596395A (fr) |
PE (1) | PE20120315A1 (fr) |
SG (1) | SG175794A1 (fr) |
TW (1) | TWI438201B (fr) |
WO (1) | WO2010126168A2 (fr) |
ZA (1) | ZA201108375B (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL236001B1 (pl) | 2012-12-21 | 2020-11-30 | Adamed Spolka Z Ograniczona Odpowiedzialnoscia | Złożona kompozycja farmaceutyczna zawierająca kandesartan cyleksetylu oraz amlodypinę, sposób jej wytwarzania oraz jednostkowa postać dawkowania zawierająca tę kompozycję |
KR101535586B1 (ko) * | 2014-08-01 | 2015-07-09 | 에스케이케미칼주식회사 | 무정형 또는 열역학적 준 안정형 리바록사반을 포함하는 약학 제제 |
KR101806004B1 (ko) * | 2015-01-30 | 2017-12-08 | 씨제이헬스케어 주식회사 | 칸데사르탄 및 암로디핀을 포함하는 약제학적 조성물 |
CN106668016B (zh) * | 2015-11-11 | 2020-06-23 | 江苏先声药业有限公司 | 阿齐沙坦和苯磺酸氨氯地平组合物的固体制剂及其制备方法 |
JP2017210435A (ja) * | 2016-05-25 | 2017-11-30 | ダイト株式会社 | イルベサルタン及びアムロジピンベシル酸塩配合錠の製造方法 |
JP2019001782A (ja) * | 2017-06-14 | 2019-01-10 | 東和薬品株式会社 | 二層錠 |
JP7101464B2 (ja) * | 2017-09-28 | 2022-07-15 | エルメッド株式会社 | アジルサルタン又はその塩及びアムロジピン又はその塩含有錠剤の品質向上方法、並びにアジルサルタン又はその塩及びアムロジピン又はその塩含有錠剤及びその製造方法 |
CN108210472A (zh) * | 2017-12-15 | 2018-06-29 | 蚌埠丰原医药科技发展有限公司 | 一种西尼地平固体分散体片剂及其制备方法 |
CN108685925B (zh) * | 2018-05-15 | 2019-12-06 | 徐州医科大学 | 一种化合物AB-38b在制备治疗糖尿病肾病药物方面的应用 |
JP2020075869A (ja) * | 2018-11-05 | 2020-05-21 | 日本ケミファ株式会社 | カルシウム拮抗剤及びアンジオテンシンii受容体拮抗剤を有効成分として含有する錠剤 |
JP2020090471A (ja) * | 2018-12-07 | 2020-06-11 | ニプロ株式会社 | アジルサルタン及びアムロジピンを含有する医薬組成物及びその製造方法 |
JP7206872B2 (ja) * | 2018-12-07 | 2023-01-18 | ニプロ株式会社 | アジルサルタン及びアムロジピンを含有する医薬組成物及びその製造方法 |
JP7441105B2 (ja) | 2020-03-31 | 2024-02-29 | 日本ジェネリック株式会社 | アジルサルタン及びアムロジピンベシル酸塩を含有するフィルムコーティング錠 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2814513B2 (ja) * | 1988-02-03 | 1998-10-22 | 吉富製薬株式会社 | 溶出性の改良された製剤組成物 |
JP3057471B2 (ja) * | 1993-06-07 | 2000-06-26 | 武田薬品工業株式会社 | アンジオテンシンii介在性諸疾患の予防または治療剤 |
CA2125251C (fr) * | 1993-06-07 | 2005-04-26 | Yoshiyuki Inada | Composition pharmaceutique pour le traitement des affections mediees par l'angiotensine ii |
EP1302462A4 (fr) | 2000-07-17 | 2007-07-18 | Takeda Pharmaceutical | Derives de sulfonate, procede de production et utilisation de ces derives |
EP1369130A1 (fr) * | 2001-03-16 | 2003-12-10 | Takeda Chemical Industries, Ltd. | Procede de fabrication d'une preparation a liberation continue |
CA2468827A1 (fr) * | 2001-12-03 | 2003-06-12 | Takeda Chemical Industries, Ltd. | Agents pour ameliorer l'etat de resistance a l'insuline |
JP4743684B2 (ja) * | 2002-05-22 | 2011-08-10 | 塩野義製薬株式会社 | 難水溶性薬物の溶出性を改善する方法 |
AU2003284596A1 (en) | 2002-11-22 | 2004-06-18 | Takeda Pharmaceutical Company Limited | Imidazole derivative, process for producing the same, and use |
EP1669352A4 (fr) | 2003-09-30 | 2008-12-17 | Takeda Pharmaceutical | Derive thiazoline et utilisation |
WO2005058823A1 (fr) | 2003-12-17 | 2005-06-30 | Takeda Pharmaceutical Company Limited | Derives d'uree, processus de production correspondant et utilisation |
TWI396686B (zh) | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
JP2006321726A (ja) * | 2005-05-17 | 2006-11-30 | Sysmex Corp | 錠剤の溶出性調整方法 |
CN101247832B (zh) * | 2005-06-27 | 2011-12-28 | 第一三共株式会社 | 含有血管紧张素ⅱ受体拮抗剂和钙通道阻断剂的药物制剂 |
WO2007001065A2 (fr) * | 2005-06-27 | 2007-01-04 | Daiichi Sankyo Company, Limited | Methode pour preparer un produit medicamenteux se presentant sous forme de granules humides |
DE102005031577A1 (de) * | 2005-07-06 | 2007-01-11 | Bayer Healthcare Ag | Pharmazeutische Darreichungsformen enthaltend eine Wirkstoffkombination von Nifedipin und/oder Nisoldipin und einem Angiotensin-II Antagonisten |
CN104324015B (zh) * | 2007-03-29 | 2018-08-28 | 第一三共株式会社 | 药物组合物 |
AR073380A1 (es) * | 2008-09-25 | 2010-11-03 | Takeda Pharmaceutical | Composicion farmaceutica solida. comprimido multicapa |
-
2010
- 2010-04-28 MX MX2011011011A patent/MX2011011011A/es not_active Application Discontinuation
- 2010-04-28 AU AU2010242308A patent/AU2010242308A1/en not_active Abandoned
- 2010-04-28 MA MA34358A patent/MA33280B1/fr unknown
- 2010-04-28 NZ NZ596395A patent/NZ596395A/xx not_active IP Right Cessation
- 2010-04-28 EP EP10719654A patent/EP2424501A2/fr not_active Withdrawn
- 2010-04-28 KR KR1020117027421A patent/KR101797776B1/ko active IP Right Grant
- 2010-04-28 EA EA201171329A patent/EA201171329A1/ru unknown
- 2010-04-28 CA CA2760073A patent/CA2760073A1/fr not_active Abandoned
- 2010-04-28 TW TW099113442A patent/TWI438201B/zh active
- 2010-04-28 JP JP2011545129A patent/JP5666471B2/ja active Active
- 2010-04-28 MY MYPI2011005206A patent/MY158158A/en unknown
- 2010-04-28 CN CN2010800289702A patent/CN102481248B/zh active Active
- 2010-04-28 WO PCT/JP2010/057923 patent/WO2010126168A2/fr active Application Filing
- 2010-04-28 GE GEAP201012480A patent/GEP20135940B/en unknown
- 2010-04-28 PE PE2011001882A patent/PE20120315A1/es not_active Application Discontinuation
- 2010-04-28 SG SG2011078391A patent/SG175794A1/en unknown
- 2010-04-28 BR BRPI1014388A patent/BRPI1014388A2/pt not_active IP Right Cessation
-
2011
- 2011-10-26 IL IL215962A patent/IL215962A0/en unknown
- 2011-10-26 DO DO2011000329A patent/DOP2011000329A/es unknown
- 2011-10-26 CL CL2011002662A patent/CL2011002662A1/es unknown
- 2011-11-08 CR CR20110581A patent/CR20110581A/es unknown
- 2011-11-15 ZA ZA2011/08375A patent/ZA201108375B/en unknown
- 2011-11-30 CO CO11164599A patent/CO6470841A2/es not_active Application Discontinuation
- 2011-11-30 EC EC2011011494A patent/ECSP11011494A/es unknown
Also Published As
Publication number | Publication date |
---|---|
WO2010126168A3 (fr) | 2011-03-03 |
EP2424501A2 (fr) | 2012-03-07 |
JP5666471B2 (ja) | 2015-02-12 |
MX2011011011A (es) | 2011-11-02 |
TW201041873A (en) | 2010-12-01 |
DOP2011000329A (es) | 2011-11-15 |
SG175794A1 (en) | 2011-12-29 |
CA2760073A1 (fr) | 2010-11-04 |
IL215962A0 (en) | 2012-01-31 |
JP2012525323A (ja) | 2012-10-22 |
CO6470841A2 (es) | 2012-06-29 |
ECSP11011494A (es) | 2011-12-30 |
CL2011002662A1 (es) | 2012-06-15 |
TWI438201B (zh) | 2014-05-21 |
ZA201108375B (en) | 2013-01-30 |
CN102481248B (zh) | 2013-12-11 |
MY158158A (en) | 2016-09-15 |
NZ596395A (en) | 2013-06-28 |
KR20120026060A (ko) | 2012-03-16 |
KR101797776B1 (ko) | 2017-11-14 |
GEP20135940B (en) | 2013-10-10 |
EA201171329A1 (ru) | 2012-05-30 |
AU2010242308A1 (en) | 2011-12-01 |
PE20120315A1 (es) | 2012-04-07 |
CR20110581A (es) | 2012-01-19 |
BRPI1014388A2 (pt) | 2016-04-05 |
CN102481248A (zh) | 2012-05-30 |
WO2010126168A2 (fr) | 2010-11-04 |
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