MA31084B1 - Derives de piperidine agonistes de gpcr - Google Patents

Derives de piperidine agonistes de gpcr

Info

Publication number
MA31084B1
MA31084B1 MA32072A MA32072A MA31084B1 MA 31084 B1 MA31084 B1 MA 31084B1 MA 32072 A MA32072 A MA 32072A MA 32072 A MA32072 A MA 32072A MA 31084 B1 MA31084 B1 MA 31084B1
Authority
MA
Morocco
Prior art keywords
piperidine derivatives
gpcr agonist
gpcr
agonist
piperidine
Prior art date
Application number
MA32072A
Other languages
English (en)
Inventor
Lisa Sarah Bertram
Matthew Colin Thor Fyfe
Revathy Perpetua Jeevaratnam
John Keily
Simon Andrew Swain
Original Assignee
Prosidion Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0700124A external-priority patent/GB0700124D0/en
Priority claimed from GB0708740A external-priority patent/GB0708740D0/en
Priority claimed from GB0719762A external-priority patent/GB0719762D0/en
Application filed by Prosidion Ltd filed Critical Prosidion Ltd
Publication of MA31084B1 publication Critical patent/MA31084B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'INVENTION CONCERNE DES COMPOSÉS REPRÉSENTÉS PAR LA FORMULE (I) : OU DES SELS ACCEPTABLES DU POINT DE VUE PHARMACEUTIQUE DE CEUX-CI, QUI SONT DES AGONISTES DE GPCR ET S'UTILISENT POUR LE TRAITEMENT DE L'OBÉSITÉ ET DU DIABÈTE.
MA32072A 2007-01-04 2009-07-03 Derives de piperidine agonistes de gpcr MA31084B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0700124A GB0700124D0 (en) 2007-01-04 2007-01-04 GPCR agonists
GB0708740A GB0708740D0 (en) 2007-05-08 2007-05-08 Gpcr agonists
GB0719762A GB0719762D0 (en) 2007-10-10 2007-10-10 GPCR agonists

Publications (1)

Publication Number Publication Date
MA31084B1 true MA31084B1 (fr) 2010-01-04

Family

ID=39203222

Family Applications (1)

Application Number Title Priority Date Filing Date
MA32072A MA31084B1 (fr) 2007-01-04 2009-07-03 Derives de piperidine agonistes de gpcr

Country Status (28)

Country Link
US (1) US20100022591A1 (fr)
EP (2) EP2383270A1 (fr)
JP (1) JP2010514829A (fr)
KR (1) KR20090104092A (fr)
CN (1) CN101627036A (fr)
AR (1) AR064736A1 (fr)
AT (1) ATE531710T1 (fr)
AU (1) AU2008203673A1 (fr)
BR (1) BRPI0806468A2 (fr)
CA (1) CA2674093A1 (fr)
CL (1) CL2008000017A1 (fr)
DK (1) DK2114931T3 (fr)
EA (1) EA015805B9 (fr)
ES (1) ES2376015T3 (fr)
HK (1) HK1135704A1 (fr)
HR (1) HRP20110964T1 (fr)
IL (1) IL199680A0 (fr)
MA (1) MA31084B1 (fr)
MX (1) MX2009007180A (fr)
NZ (1) NZ578144A (fr)
PE (1) PE20081849A1 (fr)
PL (1) PL2114931T3 (fr)
PT (1) PT2114931E (fr)
RS (1) RS52168B (fr)
SA (1) SA08280756B1 (fr)
SI (1) SI2114931T1 (fr)
TW (1) TWI380818B (fr)
WO (1) WO2008081205A1 (fr)

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ES2376015T3 (es) 2012-03-08
NZ578144A (en) 2011-03-31
TWI380818B (zh) 2013-01-01
EP2114931A1 (fr) 2009-11-11
EP2383270A1 (fr) 2011-11-02
PL2114931T3 (pl) 2012-03-30
PT2114931E (pt) 2012-01-12
HRP20110964T1 (hr) 2012-01-31
ATE531710T1 (de) 2011-11-15
IL199680A0 (en) 2010-04-15
AU2008203673A1 (en) 2008-07-10
SA08280756B1 (ar) 2011-01-24
MX2009007180A (es) 2009-07-15
WO2008081205A1 (fr) 2008-07-10
KR20090104092A (ko) 2009-10-05
US20100022591A1 (en) 2010-01-28
EA200900796A1 (ru) 2010-02-26
DK2114931T3 (da) 2012-02-13
JP2010514829A (ja) 2010-05-06
AR064736A1 (es) 2009-04-22
EA015805B9 (ru) 2012-03-30
SI2114931T1 (sl) 2012-02-29
CN101627036A (zh) 2010-01-13
TW200835489A (en) 2008-09-01
RS52168B (en) 2012-08-31
EP2114931B1 (fr) 2011-11-02
BRPI0806468A2 (pt) 2011-09-27
PE20081849A1 (es) 2009-01-26
CA2674093A1 (fr) 2008-07-10
HK1135704A1 (en) 2010-06-11
EA015805B1 (ru) 2011-12-30

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