MA28601B1 - Acide 4-hydroxy-4-methyl-piperidine-1-carboxylique (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide - Google Patents

Acide 4-hydroxy-4-methyl-piperidine-1-carboxylique (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide

Info

Publication number
MA28601B1
MA28601B1 MA29481A MA29481A MA28601B1 MA 28601 B1 MA28601 B1 MA 28601B1 MA 29481 A MA29481 A MA 29481A MA 29481 A MA29481 A MA 29481A MA 28601 B1 MA28601 B1 MA 28601B1
Authority
MA
Morocco
Prior art keywords
benzothiazol
morpholin
piperidine
methoxy
amide
Prior art date
Application number
MA29481A
Other languages
English (en)
Inventor
Alexander Flohr
Jean-Luc Moreau
Sonia Maria Poli
Claus Riemer
Lucinda Steward
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34967309&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA28601(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA28601B1 publication Critical patent/MA28601B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
MA29481A 2004-05-24 2006-11-22 Acide 4-hydroxy-4-methyl-piperidine-1-carboxylique (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide MA28601B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04102262 2004-05-24

Publications (1)

Publication Number Publication Date
MA28601B1 true MA28601B1 (fr) 2007-05-02

Family

ID=34967309

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29481A MA28601B1 (fr) 2004-05-24 2006-11-22 Acide 4-hydroxy-4-methyl-piperidine-1-carboxylique (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide

Country Status (39)

Country Link
US (1) US7368446B2 (fr)
EP (1) EP1753760B1 (fr)
JP (1) JP4668265B2 (fr)
CN (1) CN1956983B (fr)
AR (1) AR048973A1 (fr)
AT (1) ATE382619T1 (fr)
AU (1) AU2005247567B2 (fr)
BR (1) BRPI0511543B1 (fr)
CA (1) CA2567703C (fr)
CR (1) CR8703A (fr)
CY (1) CY1108104T1 (fr)
DE (1) DE602005004142T2 (fr)
DK (1) DK1753760T3 (fr)
DO (1) DOP2005000091A (fr)
EA (1) EA011279B1 (fr)
EC (1) ECSP067018A (fr)
ES (1) ES2297710T3 (fr)
GT (1) GT200500124A (fr)
HK (1) HK1105199A1 (fr)
HN (1) HN2005000238A (fr)
HR (1) HRP20080027T3 (fr)
IL (1) IL179364A (fr)
MA (1) MA28601B1 (fr)
MX (1) MXPA06013417A (fr)
MY (1) MY140011A (fr)
NO (1) NO336939B1 (fr)
NZ (1) NZ550763A (fr)
PA (1) PA8633901A1 (fr)
PE (1) PE20060274A1 (fr)
PL (1) PL1753760T3 (fr)
PT (1) PT1753760E (fr)
RS (1) RS50574B (fr)
SI (1) SI1753760T1 (fr)
SV (1) SV2006002125A (fr)
TN (1) TNSN06371A1 (fr)
TW (1) TWI358297B (fr)
UA (1) UA87142C2 (fr)
WO (1) WO2005116026A1 (fr)
ZA (1) ZA200609136B (fr)

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SE521512C2 (sv) * 2001-06-25 2003-11-11 Niconovum Ab Anordning för administrering av en substans till främre delen av en individs munhåla
DK1803444T3 (en) 2002-12-20 2019-02-25 Niconovum Ab PROCEDURE FOR PREPARING A NICOTIC PARTICULATE MATERIAL WITH A CRYSTALLINE CELLULOSE (ESPECIALLY MCC)
WO2007104573A2 (fr) 2006-03-16 2007-09-20 Niconovum Ab Composition améliorée de tabac à priser
BRPI0814672A2 (pt) * 2007-07-23 2014-09-30 Synosia Therapeutics Método de tratamento de um paciente, e de distúrbio de estresse pós-traumático, e, métodos para melhorar a resiliência em um paciente e para diagnosticar distúrbio de estresse pós-traumático em um paciente.
DK2385938T3 (en) 2009-01-12 2015-04-27 Pfizer Ltd Sulfonamidderivater
US8168785B2 (en) 2009-06-17 2012-05-01 Biotie Therapies, Inc. Benzothiazole derivatives
WO2011101861A1 (fr) 2010-01-29 2011-08-25 Msn Laboratories Limited Procédé de préparation d'inhibiteurs de la dpp-iv
US9145407B2 (en) 2010-07-09 2015-09-29 Pfizer Limited Sulfonamide compounds
WO2012060844A1 (fr) * 2010-11-05 2012-05-10 Biotie Therapies, Inc Antagonistes a2a en tant que stimulateurs de cognition et de fonction motrice
WO2013156614A1 (fr) * 2012-04-20 2013-10-24 Ucb Pharma S.A. Méthodes de traitement de la maladie de parkinson
AU2016278846B2 (en) * 2015-06-19 2021-08-05 Biotie Therapies, Inc. Controlled-release tozadenant formulations
WO2018059531A1 (fr) * 2016-09-30 2018-04-05 苏州晶云药物科技有限公司 Forme cristalline d'un médicament antagoniste du récepteur de l'adénosine a 2a , son procédé de préparation et son utilisation
KR20200043434A (ko) * 2017-08-21 2020-04-27 메르크 파텐트 게엠베하 아데노신 수용체 길항제로서의 퀴녹살린 유도체
TWI791593B (zh) * 2017-08-21 2023-02-11 德商馬克專利公司 做為腺苷受體拮抗劑之苯并咪唑衍生物
WO2019141096A1 (fr) * 2018-01-19 2019-07-25 四川科伦博泰生物医药股份有限公司 Composé d'urée substitué, son procédé de préparation et son utilisation
EP3897653A1 (fr) 2018-12-20 2021-10-27 Biotie Therapies, Inc. Méthodes de traitement du cancer à l'aide de tozadenant
DE102019110904B4 (de) 2019-04-26 2022-01-20 Helmholtz-Zentrum Dresden - Rossendorf E. V. N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-acetamid-Derivate und deren Verwendung

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LU63457A1 (fr) 1970-07-06 1971-11-12
US4028374A (en) 1975-11-03 1977-06-07 Morton-Norwich Products, Inc. Antibacterial thiocyanatobenzothiazoles
DE2656468A1 (de) 1976-12-14 1978-06-15 Boehringer Mannheim Gmbh N-(benzthiazol-2-yl)-oxamidsaeure- derivate und verfahren zu ihrer herstellung
KR930005004B1 (ko) 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
FI91859C (fi) 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi
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Also Published As

Publication number Publication date
BRPI0511543A (pt) 2008-01-02
DK1753760T3 (da) 2008-04-14
AR048973A1 (es) 2006-06-14
DE602005004142D1 (de) 2008-02-14
TNSN06371A1 (fr) 2008-02-22
ES2297710T3 (es) 2008-05-01
ATE382619T1 (de) 2008-01-15
WO2005116026A1 (fr) 2005-12-08
ECSP067018A (es) 2006-12-29
US20050261289A1 (en) 2005-11-24
EA200602048A1 (ru) 2007-06-29
HRP20080027T3 (en) 2008-05-31
MY140011A (en) 2009-11-30
MXPA06013417A (es) 2007-01-23
PE20060274A1 (es) 2006-04-14
ZA200609136B (en) 2008-07-30
PA8633901A1 (es) 2006-05-16
UA87142C2 (en) 2009-06-25
CN1956983A (zh) 2007-05-02
CN1956983B (zh) 2010-05-26
PT1753760E (pt) 2008-02-12
IL179364A (en) 2013-01-31
HK1105199A1 (en) 2008-02-06
BRPI0511543B1 (pt) 2022-05-10
DE602005004142T2 (de) 2009-01-02
EP1753760A1 (fr) 2007-02-21
TW200612937A (en) 2006-05-01
DOP2005000091A (es) 2005-06-29
JP4668265B2 (ja) 2011-04-13
PL1753760T3 (pl) 2008-06-30
US7368446B2 (en) 2008-05-06
TWI358297B (en) 2012-02-21
IL179364A0 (en) 2007-03-08
SI1753760T1 (sl) 2008-04-30
HN2005000238A (es) 2008-07-14
CY1108104T1 (el) 2014-02-12
NZ550763A (en) 2010-07-30
AU2005247567B2 (en) 2010-09-02
NO20065732L (no) 2006-12-22
SV2006002125A (es) 2006-02-15
NO336939B1 (no) 2015-11-30
JP2008500295A (ja) 2008-01-10
RS50574B (sr) 2010-05-07
EP1753760B1 (fr) 2008-01-02
EA011279B1 (ru) 2009-02-27
CR8703A (es) 2007-10-04
GT200500124A (es) 2005-12-26
AU2005247567A1 (en) 2005-12-08
CA2567703A1 (fr) 2005-12-08
CA2567703C (fr) 2013-03-05

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