SV2006002125A - (4-metoxi-7-morfolin-4-il-benzotiazol-2-il)amida del acido 4-hidroxi-4-metil-piperidin-1-carboxilico caso 22560 sv - Google Patents

(4-metoxi-7-morfolin-4-il-benzotiazol-2-il)amida del acido 4-hidroxi-4-metil-piperidin-1-carboxilico caso 22560 sv

Info

Publication number
SV2006002125A
SV2006002125A SV2005002125A SV2005002125A SV2006002125A SV 2006002125 A SV2006002125 A SV 2006002125A SV 2005002125 A SV2005002125 A SV 2005002125A SV 2005002125 A SV2005002125 A SV 2005002125A SV 2006002125 A SV2006002125 A SV 2006002125A
Authority
SV
El Salvador
Prior art keywords
benzotiazol
morfolin
metoxi
hidroxi
amida
Prior art date
Application number
SV2005002125A
Other languages
English (en)
Inventor
Alexander Flohr
Jean Luc Moreau
Sonia Maria Poli
Claus Riemer
Lucinda Steward
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34967309&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SV2006002125(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SV2006002125A publication Critical patent/SV2006002125A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE AL COMPUESTO DE FORMULA (VER FORMULA) EL CUAL ES (4-METOXI-7-MORFOLIN-4-IL-BENZOTIAZOL -2-IL)AMIDA DEL ACIDO 4-HIDROXI-4-METIL-PIPERIDIN -1-CARBOXILICO, Y SALES DE ADICION ACIDA FARMACEUTICAMENTE ACEPTABLES. SE HA DESCUBIERTO QUE EL COMPUESTO ES UTIL PARA EL TRATAMIENTO Y PREVENCION DE LA ENFERMEDAD DE ALZHEIMER, ENFERMEADAD DE PARKINSON, ENFERMEDAD DE HUNTINGTON, NEUROPROTECCION, ESQUIZOFRENIA, ANSIEDAD, DOLOR, DEFICIT DE RESPIRACION, DEPRESION, ADHD (TRASTORNO DE DEFICIT DE ATENCION E HIPERACTIVIDAD), DROGODEPENDENCIA DE AFETAMINAS, COCAINA, OPIOIDES, ETANOL, NICOTINA, CANNABINOIDES, O PARA EL TRATAMIENTO DE ASMA, RESPUESTAS ALERGICAS, HIPOXIA, ISQUEMIA, CONVULSIONES, SUSTANCIAS DE ABUSO, O PARA EL USO COMO RELAJANTES MUSCULARES, ANTIPSICOTICOS, ANTIEPILEPTICOS, ANTICONVULSIVOS Y AGENTES CARDIPROTECTORES
SV2005002125A 2004-05-24 2005-05-24 (4-metoxi-7-morfolin-4-il-benzotiazol-2-il)amida del acido 4-hidroxi-4-metil-piperidin-1-carboxilico caso 22560 sv SV2006002125A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04102262 2004-05-24

Publications (1)

Publication Number Publication Date
SV2006002125A true SV2006002125A (es) 2006-02-15

Family

ID=34967309

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2005002125A SV2006002125A (es) 2004-05-24 2005-05-24 (4-metoxi-7-morfolin-4-il-benzotiazol-2-il)amida del acido 4-hidroxi-4-metil-piperidin-1-carboxilico caso 22560 sv

Country Status (39)

Country Link
US (1) US7368446B2 (es)
EP (1) EP1753760B1 (es)
JP (1) JP4668265B2 (es)
CN (1) CN1956983B (es)
AR (1) AR048973A1 (es)
AT (1) ATE382619T1 (es)
AU (1) AU2005247567B2 (es)
BR (1) BRPI0511543B1 (es)
CA (1) CA2567703C (es)
CR (1) CR8703A (es)
CY (1) CY1108104T1 (es)
DE (1) DE602005004142T2 (es)
DK (1) DK1753760T3 (es)
DO (1) DOP2005000091A (es)
EA (1) EA011279B1 (es)
EC (1) ECSP067018A (es)
ES (1) ES2297710T3 (es)
GT (1) GT200500124A (es)
HK (1) HK1105199A1 (es)
HN (1) HN2005000238A (es)
HR (1) HRP20080027T3 (es)
IL (1) IL179364A (es)
MA (1) MA28601B1 (es)
MX (1) MXPA06013417A (es)
MY (1) MY140011A (es)
NO (1) NO336939B1 (es)
NZ (1) NZ550763A (es)
PA (1) PA8633901A1 (es)
PE (1) PE20060274A1 (es)
PL (1) PL1753760T3 (es)
PT (1) PT1753760E (es)
RS (1) RS50574B (es)
SI (1) SI1753760T1 (es)
SV (1) SV2006002125A (es)
TN (1) TNSN06371A1 (es)
TW (1) TWI358297B (es)
UA (1) UA87142C2 (es)
WO (1) WO2005116026A1 (es)
ZA (1) ZA200609136B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE521512C2 (sv) * 2001-06-25 2003-11-11 Niconovum Ab Anordning för administrering av en substans till främre delen av en individs munhåla
DK1578422T3 (da) * 2002-12-20 2007-07-02 Niconovum Ab Fysisk og kemisk stabilt nikotin-indeholdende partikelholdigt materiale
CA2646942C (en) 2006-03-16 2014-07-29 Niconovum Ab Improved snuff composition
BRPI0814672A2 (pt) * 2007-07-23 2014-09-30 Synosia Therapeutics Método de tratamento de um paciente, e de distúrbio de estresse pós-traumático, e, métodos para melhorar a resiliência em um paciente e para diagnosticar distúrbio de estresse pós-traumático em um paciente.
RS53941B1 (en) 2009-01-12 2015-08-31 Pfizer Limited SULFONAMID DERIVATIVES
US8168785B2 (en) * 2009-06-17 2012-05-01 Biotie Therapies, Inc. Benzothiazole derivatives
WO2011101861A1 (en) 2010-01-29 2011-08-25 Msn Laboratories Limited Process for preparation of dpp-iv inhibitors
JP5872552B2 (ja) 2010-07-09 2016-03-01 ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ 化学化合物
WO2012060844A1 (en) * 2010-11-05 2012-05-10 Biotie Therapies, Inc A2a antagonists as cognition and motor function enhancers
WO2013156614A1 (en) * 2012-04-20 2013-10-24 Ucb Pharma S.A. Methods for treating parkinson's disease
US10653699B2 (en) 2015-06-19 2020-05-19 Biotie Therapies, Inc. Controlled-release tozadenant formulations
WO2018059531A1 (zh) * 2016-09-30 2018-04-05 苏州晶云药物科技有限公司 一种腺苷a2a受体拮抗剂药物的晶型及其制备方法和用途
SG11202001340VA (en) * 2017-08-21 2020-03-30 Merck Patent Gmbh Quinoxaline derivatives as adenosine receptor antagonists
JP7287952B2 (ja) * 2017-08-21 2023-06-06 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング アデノシン受容体アンタゴニストとしてのベンズイミダゾール誘導体
WO2019141096A1 (zh) * 2018-01-19 2019-07-25 四川科伦博泰生物医药股份有限公司 取代脲类化合物及其制备方法和用途
JP2022515741A (ja) 2018-12-20 2022-02-22 バイオティー セラピーズ インコーポレイテッド トザデナントを使用して癌を処置する方法
DE102019110904B4 (de) 2019-04-26 2022-01-20 Helmholtz-Zentrum Dresden - Rossendorf E. V. N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-acetamid-Derivate und deren Verwendung

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH505543A (de) 1968-11-01 1971-04-15 Ciba Geigy Ag Schädlingsbekämpfungsmittel
NL7109150A (es) 1970-07-06 1972-01-10
US4028374A (en) 1975-11-03 1977-06-07 Morton-Norwich Products, Inc. Antibacterial thiocyanatobenzothiazoles
DE2656468A1 (de) 1976-12-14 1978-06-15 Boehringer Mannheim Gmbh N-(benzthiazol-2-yl)-oxamidsaeure- derivate und verfahren zu ihrer herstellung
KR930005004B1 (ko) 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
FI91859C (fi) 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi
IL90337A0 (en) 1988-05-24 1989-12-15 Pfizer Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents
WO1990015801A1 (en) 1989-06-22 1990-12-27 Pfizer Inc. Substituted sulfonamides and related compounds in the treatment of asthma, arthritis and related diseases
DE59005183D1 (de) 1989-11-10 1994-05-05 Agrolinz Agrarchemikalien Verfahren zur Herstellung reiner, unsymmetrisch disubstituierter Harnstoffe.
DK0604657T3 (da) 1992-05-21 2000-04-17 Otsuka Pharma Co Ltd Phosphonsyrediesterderivat
FR2753970B1 (fr) 1996-10-01 1998-10-30 Synthelabo Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique
JPH11130761A (ja) 1997-10-24 1999-05-18 Otsuka Pharmaceut Co Ltd ベンゾチアゾール誘導体
WO1999024035A1 (en) 1997-11-10 1999-05-20 Bristol-Myers Squibb Company Benzothiazole protein tyrosine kinase inhibitors
CN1288462A (zh) 1998-01-23 2001-03-21 法玛西雅厄普约翰美国公司 噁唑烷酮组合库、组合物和制备方法
EP1117663A2 (en) 1998-09-30 2001-07-25 Neurogen Corporation 2-piperazino alkylamino benzoazole derivatives: dopamine receptor subtype specific ligands
UA71587C2 (uk) 1998-11-10 2004-12-15 Шерінг Акцієнгезелльшафт Аміди антранілової кислоти та їхнє застосування як лікарських засобів
GB9824579D0 (en) 1998-11-10 1999-01-06 Novartis Ag Organic compounds
IL133680A0 (en) 1999-09-10 2001-04-30 Can Fite Technologies Ltd Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist
WO2001087786A1 (en) 2000-05-12 2001-11-22 Corning Incorporated Method for manufacturing an optical fiber preform with a protective coating
ES2299504T3 (es) * 2000-06-21 2008-06-01 F. Hoffmann-La Roche Ag Derivados de benzotiazol para el tratamiento de la enfermedad de alzheimer y de la enfermedad de parkinson.
US6727247B2 (en) * 2001-12-10 2004-04-27 Hoffman-La Roche Inc. Substituted benzothiazole amide derivatives
US6713499B2 (en) * 2001-12-12 2004-03-30 Hoffman-La Roche Inc. 7-Amino-benzothiazole derivatives

Also Published As

Publication number Publication date
AR048973A1 (es) 2006-06-14
HN2005000238A (es) 2008-07-14
HK1105199A1 (en) 2008-02-06
ES2297710T3 (es) 2008-05-01
EP1753760B1 (en) 2008-01-02
NO20065732L (no) 2006-12-22
JP4668265B2 (ja) 2011-04-13
IL179364A (en) 2013-01-31
US7368446B2 (en) 2008-05-06
SI1753760T1 (sl) 2008-04-30
MA28601B1 (fr) 2007-05-02
JP2008500295A (ja) 2008-01-10
MXPA06013417A (es) 2007-01-23
PL1753760T3 (pl) 2008-06-30
CY1108104T1 (el) 2014-02-12
IL179364A0 (en) 2007-03-08
AU2005247567B2 (en) 2010-09-02
CN1956983B (zh) 2010-05-26
TNSN06371A1 (fr) 2008-02-22
US20050261289A1 (en) 2005-11-24
PT1753760E (pt) 2008-02-12
DE602005004142D1 (de) 2008-02-14
EA200602048A1 (ru) 2007-06-29
DOP2005000091A (es) 2005-06-29
AU2005247567A1 (en) 2005-12-08
RS50574B (sr) 2010-05-07
WO2005116026A1 (en) 2005-12-08
ATE382619T1 (de) 2008-01-15
ECSP067018A (es) 2006-12-29
PA8633901A1 (es) 2006-05-16
EA011279B1 (ru) 2009-02-27
TWI358297B (en) 2012-02-21
DE602005004142T2 (de) 2009-01-02
ZA200609136B (en) 2008-07-30
NZ550763A (en) 2010-07-30
DK1753760T3 (da) 2008-04-14
EP1753760A1 (en) 2007-02-21
CA2567703A1 (en) 2005-12-08
CN1956983A (zh) 2007-05-02
MY140011A (en) 2009-11-30
TW200612937A (en) 2006-05-01
GT200500124A (es) 2005-12-26
BRPI0511543B1 (pt) 2022-05-10
BRPI0511543A (pt) 2008-01-02
PE20060274A1 (es) 2006-04-14
CA2567703C (en) 2013-03-05
NO336939B1 (no) 2015-11-30
CR8703A (es) 2007-10-04
HRP20080027T3 (en) 2008-05-31
UA87142C2 (en) 2009-06-25

Similar Documents

Publication Publication Date Title
SV2006002125A (es) (4-metoxi-7-morfolin-4-il-benzotiazol-2-il)amida del acido 4-hidroxi-4-metil-piperidin-1-carboxilico caso 22560 sv
CR8649A (es) Derivados de formamidina para el tratamiento de enfermedades
DOP2006000169A (es) Inhibidores espiropiperidina de beta-secretasa para el tratamiento de la enfermedad de alzheimer
PA8621901A1 (es) Derivados de sulfonamida para el tratamiento de enfermedades
UY30411A1 (es) Derivados sustituidos del acetato de 2,3,4,-tetrahidroimidazo-[1,5-a]-pirimidin-6-amina, composiciones farmacéuticas y aplicaciones
UY30274A1 (es) Derivados sustituidos de la n-(4-metil-1,3-tiazol-2-il)guanidina, formulaciones farmacéuticas conteniéndolo y aplicaciones
ECSP066730A (es) Compuestos y procedimientos para uso
PA8627001A1 (es) Compuestos para el tratamiento de enfermedades
CR10343A (es) Aminotetrahidropiranos como inihibidores de dipeptidil peptidasa-iv para el tratamiento o prevencion de diabetes
GT200600013A (es) Compuestos organicos
HN2011001256A (es) Aminotetrahidropiranos como inhibidores de dipeptidil peptidasa-iv para el tratmiento o prevencion de diabetes
PA8622401A1 (es) Derivados de acido 7-fenilamino-4-quinolona-3-carboxilico,procesos para su preparacion y su uso como medicamentos
UY29919A1 (es) Derivados sustituidos de 3,4-dihidroisoquinolin-1-amino-trifluoroacetato, sus composiciones farmacéuticas y aplicaciones
PA8627201A1 (es) Compuestos de imidazol para el tratamiento de trastornos neurodegenerativos
UY30812A1 (es) Sulfonatos { 2-amino-4-[r-fenil]-1-metil-5-oxo-4,5-dihidro-1 h-imidazol-4-il}fenil sustituidos, composiciones conteniéndolos y aplicaciones
DOP2005000006A (es) "derivados de sulfonamida para el tratamiento de enfermedades"
CR10700A (es) Derivados de sulfonamida
UY30377A1 (es) Inhibidores triciclicos fusionados de sulfonamida de gama-secretasa
EA200601510A1 (ru) Производные фенилэтаноламина в качестве бета-2-агонистов
PA8657701A1 (es) Derivado de quinolina, su uso, preparacion y medicamento que lo contiene
DE602006010397D1 (de) Substituierte cyclohexanone
ECSP099045A (es) Sal xinafoato de un compuesto de 5-oxazol-2-il-quinolina sustituido
PA8642901A1 (es) Amidas del acido 5 y 6-aminoalquil indol-2-carboxilico 3-sustituidas y analogos relacionados como inhibidores de la caseina cinasa i
CU23801B7 (es) Análogos de pirazol
PE20061100A1 (es) Sales de fosfato de 6-dimetilaminometil-1-(3-metoxifenil)-1,3-dihidroxicliclohexano