MA26412A1 - Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Info

Publication number
MA26412A1
MA26412A1 MA24431A MA24431A MA26412A1 MA 26412 A1 MA26412 A1 MA 26412A1 MA 24431 A MA24431 A MA 24431A MA 24431 A MA24431 A MA 24431A MA 26412 A1 MA26412 A1 MA 26412A1
Authority
MA
Morocco
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
novel taxoids
taxoids
Prior art date
Application number
MA24431A
Other languages
English (en)
French (fr)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of MA26412A1 publication Critical patent/MA26412A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MA24431A 1995-12-22 1996-12-18 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent MA26412A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515379A FR2742751B1 (fr) 1995-12-22 1995-12-22 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
MA26412A1 true MA26412A1 (fr) 2004-12-20

Family

ID=9485871

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24431A MA26412A1 (fr) 1995-12-22 1996-12-18 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Country Status (40)

Country Link
US (1) US5728849A (enEXAMPLES)
EP (1) EP0876362B1 (enEXAMPLES)
JP (1) JP3953106B2 (enEXAMPLES)
KR (1) KR100500351B1 (enEXAMPLES)
CN (1) CN1103766C (enEXAMPLES)
AR (1) AR005197A1 (enEXAMPLES)
AT (1) ATE250593T1 (enEXAMPLES)
AU (1) AU712597B2 (enEXAMPLES)
BG (1) BG63204B1 (enEXAMPLES)
BR (1) BR9612135A (enEXAMPLES)
CA (1) CA2238884C (enEXAMPLES)
CO (1) CO4520184A1 (enEXAMPLES)
CZ (1) CZ294972B6 (enEXAMPLES)
DE (1) DE69630145T2 (enEXAMPLES)
DK (1) DK0876362T3 (enEXAMPLES)
DZ (1) DZ2149A1 (enEXAMPLES)
EA (1) EA001533B1 (enEXAMPLES)
ES (1) ES2202490T3 (enEXAMPLES)
FR (1) FR2742751B1 (enEXAMPLES)
HU (1) HU225032B1 (enEXAMPLES)
IL (1) IL124994A (enEXAMPLES)
IN (4) IN186768B (enEXAMPLES)
MA (1) MA26412A1 (enEXAMPLES)
MX (1) MX9804688A (enEXAMPLES)
MY (1) MY113934A (enEXAMPLES)
NO (1) NO317358B1 (enEXAMPLES)
NZ (1) NZ324337A (enEXAMPLES)
OA (1) OA10700A (enEXAMPLES)
PE (1) PE25198A1 (enEXAMPLES)
PL (1) PL189311B1 (enEXAMPLES)
PT (1) PT876362E (enEXAMPLES)
RO (1) RO116194B1 (enEXAMPLES)
SK (1) SK282835B6 (enEXAMPLES)
TN (1) TNSN96169A1 (enEXAMPLES)
TR (1) TR199801179T2 (enEXAMPLES)
TW (1) TW371659B (enEXAMPLES)
UA (1) UA48205C2 (enEXAMPLES)
UY (1) UY24386A1 (enEXAMPLES)
WO (1) WO1997023473A1 (enEXAMPLES)
ZA (1) ZA9610737B (enEXAMPLES)

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GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
PL350028A1 (en) 2000-02-02 2002-10-21 Univ Florida State Res Found C10 carbonate substituted taxanes as antitumor agents
CN101293888B (zh) * 2001-02-24 2013-09-25 勃林格殷格翰制药两合公司 黄嘌呤衍生物、其制法及其作为药物组合物的用途
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
WO2004103344A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
EP1669358A1 (en) * 2004-12-07 2006-06-14 Aventis Pharma S.A. Cytotoxic agents comprising new taxanes
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
UA97244C2 (en) 2006-05-04 2012-01-25 Берингер Ингельхайм Интернациональ Гмбх Polymorphs of 1-((4-methyfquinazolin-2-yl)methyl)-3-methyl-7- (2-butyn-1-yl)-8-(3-(r)-aminopiperidin-l-yl)xanthine
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
ES2733348T3 (es) * 2007-08-17 2019-11-28 Boehringer Ingelheim Int Derivados de purina para uso en el tratamiento de enfermedades relacionadas con FAP
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
BRPI0916997A2 (pt) 2008-08-06 2020-12-15 Boehringer Ingelheim International Gmbh Inibidor de dpp-4 e seu uso
BRPI0917675A2 (pt) * 2008-08-15 2015-12-01 Boehringer Ingelheim Int compostos orgânicos para cura de ferida
US8513264B2 (en) 2008-09-10 2013-08-20 Boehringer Ingelheim International Gmbh Combination therapy for the treatment of diabetes and related conditions
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
KR20110103968A (ko) 2008-12-23 2011-09-21 베링거 인겔하임 인터내셔날 게엠베하 유기 화합물의 염 형태
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
EA034869B1 (ru) 2009-11-27 2020-03-31 Бёрингер Ингельхайм Интернациональ Гмбх Лечение генотипированных пациентов с диабетом ингибиторами дпп-4, такими как линаглиптин
CN102946875A (zh) 2010-05-05 2013-02-27 贝林格尔.英格海姆国际有限公司 组合疗法
JP5843855B2 (ja) 2010-06-24 2016-01-13 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 糖尿病療法
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
ES2934843T3 (es) 2011-07-15 2023-02-27 Boehringer Ingelheim Int Derivado de quinazolina dimérico sustituido, su preparación y su uso en composiciones farmacéuticas para el tratamiento de la diabetes de tipo I y II
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
EP2849755A1 (en) 2012-05-14 2015-03-25 Boehringer Ingelheim International GmbH A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
JP6218811B2 (ja) 2012-05-14 2017-10-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｓｉｒｓ及び／又は敗血症の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
WO2014080251A1 (en) 2012-11-24 2014-05-30 Hangzhou Dac Biotech Co., Ltd. Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
FR3010839B1 (fr) * 2013-09-17 2017-04-21 Schneider Electric Ind Sas Dispositif de raccordement electrique d'au moins un conducteur dans une borne appartenant a un appareil electrique
FI3122757T3 (fi) 2014-02-28 2023-10-10 Hangzhou Dac Biotech Co Ltd Varautuneita linkkereitä ja niiden konjugointikäyttötapoja
ES2950384T3 (es) 2014-02-28 2023-10-09 Boehringer Ingelheim Int Uso médico de un inhibidor de DPP-4
JP6759326B2 (ja) 2015-07-12 2020-09-23 ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ．Ｈａｎｇｚｈｏｕ Ｄａｃ Ｂｉｏｔｅｃｈ Ｃｏ．，Ｌｔｄ． 細胞結合分子の共役のための架橋連結体
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
JP2019517542A (ja) 2016-06-10 2019-06-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング リナグリプチンおよびメトホルミンの組合せ
EP3538080A4 (en) 2016-11-14 2020-07-08 Hangzhou Dac Biotech Co., Ltd. CONJUGATION LINERS, MEDICAMENT-MOLECULE CONJUGATES TO A CELL CONTAINING THE SAME, METHODS OF PREPARING AND USING SUCH CONJUGATES WITH THE BINDERS
AU2021362997A1 (en) 2021-11-03 2024-05-16 Hangzhou Dac Biotech Co., Ltd. Specific conjugation of an antibody

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017724C1 (ru) * 1990-07-12 1994-08-15 Дзе Юниверсити оф Канзас Способ получения производных таксола
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
ATE181551T1 (de) * 1992-04-17 1999-07-15 Abbott Lab Taxol-derivate
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
IL107950A (en) * 1992-12-15 2001-04-30 Upjohn Co 7β, 8β - METHANO-TAXOLS, THEIR PREPARATION AND ANTINEOPLASTIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
SK85398A3 (en) 1998-11-04
OA10700A (fr) 2002-11-27
UA48205C2 (uk) 2002-08-15
WO1997023473A1 (fr) 1997-07-03
TR199801179T2 (xx) 1998-10-21
EA199800588A1 (ru) 1998-12-24
UY24386A1 (es) 2001-08-27
NO317358B1 (no) 2004-10-18
CZ196198A3 (cs) 1998-09-16
IL124994A0 (en) 1999-01-26
PE25198A1 (es) 1998-05-10
HU225032B1 (en) 2006-05-29
ZA9610737B (en) 1997-06-27
IL124994A (en) 2000-12-06
HUP9904046A3 (en) 2001-08-28
TNSN96169A1 (fr) 2005-03-15
HK1017895A1 (en) 1999-12-03
AR005197A1 (es) 1999-04-14
CO4520184A1 (es) 1997-10-15
HUP9904046A1 (hu) 2001-04-28
MX9804688A (es) 1998-10-31
IN188469B (enEXAMPLES) 2002-09-28
BG63204B1 (bg) 2001-06-29
PT876362E (pt) 2004-02-27
CA2238884C (fr) 2007-02-06
ES2202490T3 (es) 2004-04-01
IN186768B (enEXAMPLES) 2001-11-03
SK282835B6 (sk) 2002-12-03
KR19990076680A (ko) 1999-10-15
IN188680B (enEXAMPLES) 2002-10-26
IN188470B (enEXAMPLES) 2002-09-28
JP2000502671A (ja) 2000-03-07
EP0876362B1 (fr) 2003-09-24
NZ324337A (en) 2000-03-27
MY113934A (en) 2002-06-29
NO982580D0 (no) 1998-06-05
AU712597B2 (en) 1999-11-11
BR9612135A (pt) 1999-07-13
NO982580L (no) 1998-06-05
PL327405A1 (en) 1998-12-07
BG102569A (en) 1999-04-30
FR2742751B1 (fr) 1998-01-30
TW371659B (en) 1999-10-11
CN1205697A (zh) 1999-01-20
DZ2149A1 (fr) 2002-10-23
CN1103766C (zh) 2003-03-26
EA001533B1 (ru) 2001-04-23
JP3953106B2 (ja) 2007-08-08
DE69630145D1 (de) 2003-10-30
CZ294972B6 (cs) 2005-04-13
FR2742751A1 (fr) 1997-06-27
KR100500351B1 (ko) 2005-12-21
RO116194B1 (ro) 2000-11-30
DE69630145T2 (de) 2004-07-15
ATE250593T1 (de) 2003-10-15
US5728849A (en) 1998-03-17
PL189311B1 (pl) 2005-07-29
AU1180997A (en) 1997-07-17
EP0876362A1 (fr) 1998-11-11
DK0876362T3 (da) 2004-02-02
CA2238884A1 (fr) 1997-07-03

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