LV13249B - Composition inhibiting matrix-metallproteinases for the treatmentof neoplastic diseases - Google Patents
Composition inhibiting matrix-metallproteinases for the treatmentof neoplastic diseases Download PDFInfo
- Publication number
- LV13249B LV13249B LVP-04-88A LV040088A LV13249B LV 13249 B LV13249 B LV 13249B LV 040088 A LV040088 A LV 040088A LV 13249 B LV13249 B LV 13249B
- Authority
- LV
- Latvia
- Prior art keywords
- composition
- matrix metalloproteinase
- diseases
- matrix
- ascorbic acid
- Prior art date
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Classifications
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A—HUMAN NECESSITIES
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Claims (15)
- LV 13249 PRETENZIJAS 1. Bioķīmisku vielu kompozīcija, kas satur katehīna savienojumu, antioksidantu, prolīnu un lizīnu, kas ir efektīva matrices metālproteināzes inhibēšanā.
- 2. Kompozīcija saskaņā ar 1. punktu, kurā matrices metālproteināze ir izvēlēta no grupas, kas sastāv no matrices metālproteināzes 1, matrices metālproteināzes 2, matrices metālproteināzes 3, matrices metālproteināzes 4, matrices metālproteināzes 5, matrices metālproteināzes 6, matrices metālproteināzes 7, matrices metālproteināzes 8, matrices metālproteināzes 9, matrices metālproteināzes 10, matrices metālproteināzes 11, matrices metālproteināzes 12 un matrices metālproteināzes 14.
- 3. Kompozīcijas saskaņā ar 1. punktu pielietojums farmaceitiskas kompozīcijas pagatavošanai cilvēku slimību, kas saistītas ar paaugstinātu matrices metālproteināzes aktivitāti, ārstēšanai.
- 4. Pielietojums saskaņā ar 3. punktu, kurā cilvēku slimība ir izvēlēta no grupas, kas sastāv no neoplastiskām slimībām, iekaisuma slimībām, infekcijas slimībām, kardiovaskulārām slimībām, deģeneratīvām slimībām, neiroloģiskām slimībām un autoimūnām slimībām.
- 5. Kompozīcijas saskaņā ar 1. punktu pielietojums farmaceitiskas kompozīcijas pagatavošanai neoplastisku slimību, kas saistītas ar ārpusšūnu matrices pārmērīgu degradāciju, ārstēšanai.
- 6. Kompozīcija saskaņā ar 1. vai 2. punktu vai pielietojums saskaņā ar jebkuru no punktiem 3. - 5., kurā katehīns ir izvēlēts no grupas, kas sastāv no epikatehīniem, epigallokatehīna, epikatehīna gallāta un epigallokatehīna gallāta.
- 7. Kompozīcija saskaņā ar 1. vai 2. punktu vai pielietojums saskaņā ar jebkuru no punktiem 3. - 5., kurā antioksidants ir izvēlēts no grupas, kas sastāv no 2 askorbinskabes, tokoferoliem, tokotrienoliem, karotinoidiem, glutationa, a-taukskābes, ubihinoliem, bioflavonoldiem un karnitīna.
- 8. Kompozīcija saskaņā ar 1. vai 2. punktu vai pielietojums saskaņā ar jebkuru no punktiem 3. - 5., kurā antioksidants ir askorbīnskābe.
- 9. Kompozīcija vai pielietojums saskaņā ar 8. punktu, kurā askorbīnskābe papildus satur askorbāta prekursorus, askorbāta metabolītus un askorbīnskābes sāli.
- 10. Kompozīcija saskaņā ar 1. vai 2. punktu vai pielietojums saskaņā ar jebkuru no punktiem 3.-5., kurā antioksidants papildus satur folijskābi.
- 11. Kompozīcija vai pielietojums saskaņā ar 10. punktu, kurā folijskābe ir folāts.
- 12. Kompozīcija saskaņā ar 1. vai 2. punktu vai pielietojums saskaņā ar jebkuru no punktiem 3.-5., kurā kompozīcija papildus satur selēnu.
- 13. Kompozīcija vai pielietojums saskaņā ar 12. punktu, kurā selēns ir izvēlēts no grupas, kas sastāv no selenīta un metilselenāta.
- 14. Farmaceitiska kompozīcija, kas satur kompozīciju saskaņā ar 1. punktu.
- 15. Farmaceitiska kompozīcija saskaņā ar 14. punktu, kurā šī farmaceitiskā kompozīcija ir izmantojama orālai lietošanai, parentālai lietošanai vai lokālai lietošanai.
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| US6939860B2 (en) * | 2002-01-08 | 2005-09-06 | Matthias Rath | Composition and method for treatment of neoplastic diseases associated with elevated matrix metalloproteinase activities using catechin compounds |
| US20050079234A1 (en) * | 2003-08-27 | 2005-04-14 | Chiang Yang Chi | Compositions comprising herbs and method for immunomodulation |
| KR20050070385A (ko) * | 2003-12-30 | 2005-07-07 | (주)현덕비엔티 | 폴리페놀과, 아스코르빈산 또는 그 유도체를 함유하는항암치료 보조용 조성물 |
| US20080160099A1 (en) * | 2004-11-10 | 2008-07-03 | The Trustees Of Columbia University In The City Of New York | Methods For Treating or Preventing a Vascular Disease |
| ES2246737B1 (es) * | 2005-06-09 | 2006-12-01 | Jose Juan Rodriguez Jerez | "composicion farmaceutica que comprende lisina y usos correspondientes". |
| ES2497766T3 (es) * | 2005-12-29 | 2014-09-23 | Mitsui Norin Co., Ltd | Composiciones y procedimientos de sensibilizar a oxacilina Staphylococcus aureus resistente a meticilina |
| US20070265211A1 (en) * | 2006-05-12 | 2007-11-15 | Matthias Rath | Novel composition and method effective in inhibiting the atherogenic process |
| US20100055205A1 (en) * | 2008-08-29 | 2010-03-04 | Kristina Mains | Functional consumable compositions for promoting skin health and methods for using the same |
| EP2179722A1 (en) * | 2008-10-24 | 2010-04-28 | Heinrich-Pette-Institut für experimentelle Virologie und Immunologie | Topical formation for preventing sexual transmission of viral infection |
| ES2534245T3 (es) | 2008-11-04 | 2015-04-20 | Vymedic, Llc | Formulaciones de suplemento antiviral |
| JP4786000B2 (ja) * | 2009-10-16 | 2011-10-05 | 株式会社カネカ | 還元型補酵素ｑ１０の製造方法、安定化方法及びそれを含有する組成物 |
| EP2649994B1 (de) * | 2011-01-31 | 2017-08-30 | LUCOLAS-M.D. Ltd. | Kombinationen von aromatase inhibitoren und antioxidanzien |
| KR101829330B1 (ko) | 2011-04-13 | 2018-02-20 | (주)아모레퍼시픽 | 염증성 피부 노화 억제 물질 스크리닝 방법 |
| CN102526170B (zh) * | 2011-12-31 | 2015-04-29 | 许学志 | 抗结核杆菌的儿茶提取物组合物、其制备方法及含有它们的药物制剂和应用 |
| BE1023772B9 (fr) * | 2013-05-17 | 2017-08-02 | Valore | Composition a base d'un complexe de (+)-catechine et d'acide amine pour le traitement et la prevention du cancer |
| CN104096058A (zh) * | 2014-07-02 | 2014-10-15 | 胥玲 | 一种治疗扩张型心肌病的中药药丸 |
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| US5817695A (en) * | 1997-12-24 | 1998-10-06 | Pellico; Michael A. | Nutritional product with high fat, low carbohydrate and amino acid imbalance |
| KR20020016833A (ko) | 1999-06-15 | 2002-03-06 | 뉴트리-로직스, 인크. | 발병 감소에 유용한 영양 제제, 관련 치료 방법 및 성분스크리닝 방법 |
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| US7041669B2 (en) * | 2002-02-25 | 2006-05-09 | Boehringer Ingelheim Pharmaceuticals, Inc. | 1,4-benzofused urea compounds useful in treating cytokine mediated diseases |
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- 2002-01-31 NZ NZ533353A patent/NZ533353A/en unknown
- 2002-01-31 AT AT02712877T patent/ATE439833T1/de active
- 2002-01-31 CZ CZ2004853A patent/CZ2004853A3/cs unknown
- 2002-01-31 CN CNA028269543A patent/CN1612731A/zh active Pending
- 2002-01-31 DE DE60233433T patent/DE60233433D1/de not_active Expired - Lifetime
- 2002-01-31 SK SK277-2004A patent/SK2772004A3/sk not_active Application Discontinuation
- 2002-01-31 MX MXPA04006627A patent/MXPA04006627A/es active IP Right Grant
- 2002-01-31 EP EP02712877A patent/EP1463498B1/en not_active Expired - Lifetime
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2003
- 2003-09-05 NO NO20033949A patent/NO20033949L/no not_active Application Discontinuation
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2004
- 2004-06-22 ZA ZA200404915A patent/ZA200404915B/en unknown
- 2004-08-03 HR HR20040705A patent/HRP20040705A2/hr not_active Application Discontinuation
- 2004-08-05 LT LT2004074A patent/LT5215B/lt unknown
- 2004-09-06 LV LVP-04-88A patent/LV13249B/en unknown
- 2004-09-15 US US10/942,723 patent/US20050032715A1/en not_active Abandoned
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2005
- 2005-08-24 US US11/211,389 patent/US20050281794A1/en not_active Abandoned
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2008
- 2008-07-16 AU AU2008203157A patent/AU2008203157A1/en not_active Abandoned
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