LV12991B - Use of strains of the parapox ovis virus against organ fibrosis - Google Patents

Use of strains of the parapox ovis virus against organ fibrosis Download PDF

Info

Publication number
LV12991B
LV12991B LVP-03-13A LV030013A LV12991B LV 12991 B LV12991 B LV 12991B LV 030013 A LV030013 A LV 030013A LV 12991 B LV12991 B LV 12991B
Authority
LV
Latvia
Prior art keywords
der
die
von
manufacture
organ fibrosis
Prior art date
Application number
LVP-03-13A
Other languages
English (en)
Latvian (lv)
Inventor
Claudia Hirth-Dietrich
Tobias Schlapp
Angela Siegling
Andreas Knorr
Olaf Weber
Gudrun Theiss
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10122233A external-priority patent/DE10122233A1/de
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of LV12991B publication Critical patent/LV12991B/lv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24211—Parapoxvirus, e.g. Orf virus
    • C12N2710/24232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LVP-03-13A 2000-07-11 2003-02-11 Use of strains of the parapox ovis virus against organ fibrosis LV12991B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10033581 2000-07-11
DE10122233A DE10122233A1 (de) 2000-07-11 2001-05-08 Verwendung von Stämmen des Parapoxvirus ovis gegen Organfibrosen

Publications (1)

Publication Number Publication Date
LV12991B true LV12991B (en) 2003-08-20

Family

ID=26006334

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-03-13A LV12991B (en) 2000-07-11 2003-02-11 Use of strains of the parapox ovis virus against organ fibrosis

Country Status (30)

Country Link
US (1) US6632647B2 (lt)
EP (1) EP1303302B1 (lt)
JP (1) JP5106736B2 (lt)
CN (1) CN1452496B (lt)
AR (1) AR028800A1 (lt)
AU (2) AU8582701A (lt)
BG (1) BG107447A (lt)
CA (1) CA2415399C (lt)
CZ (1) CZ200372A3 (lt)
DK (1) DK200300014A (lt)
EE (1) EE200300019A (lt)
FI (1) FI20030038A (lt)
GB (1) GB2383752B (lt)
HK (1) HK1054330B (lt)
HR (1) HRP20030097A2 (lt)
HU (1) HU227668B1 (lt)
IL (1) IL153826A0 (lt)
LT (1) LT5064B (lt)
LU (1) LU90996B1 (lt)
LV (1) LV12991B (lt)
MA (1) MA25765A1 (lt)
MX (1) MXPA03000278A (lt)
NO (1) NO20030081L (lt)
NZ (1) NZ523535A (lt)
PL (1) PL360839A1 (lt)
RU (1) RU2003104522A (lt)
SE (1) SE0300033L (lt)
SI (1) SI21171A (lt)
SK (1) SK382003A3 (lt)
WO (1) WO2002004019A2 (lt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19922407A1 (de) * 1999-05-14 2000-11-16 Bayer Ag Organ-, gewebs- und zellspezifisches Immuntherapeutikum für chronische virale Infektionen, sowie entzündliche, degenerative und proliferative Erkrankungen insbesondere der Leber sowie Krebs auf der Basis von rekombinantem Parapoxvirus
US6752995B2 (en) * 2002-04-15 2004-06-22 Board Of Regents, The University Of Texas System Nucleic acid and polypeptide sequences useful as adjuvants
US6844000B2 (en) 2001-12-07 2005-01-18 Bayer Pharmaceuticals Corporation Use of Parapox B2L protein to treat cancer and modify immune responses
EP1574211A1 (en) 2004-03-09 2005-09-14 Inserm Use of antagonists of the CB1 receptor for the manufacture of a composition useful for the treatment of hepatic diseases
WO2012045473A1 (en) * 2010-10-07 2012-04-12 Technische Universität München Viruses for the treatment of fibrosis
WO2017141942A1 (ja) * 2016-02-16 2017-08-24 国立大学法人大阪大学 線維化を治療するための医薬組成物
TW201919675A (zh) * 2017-09-07 2019-06-01 德商艾庫瑞斯公司 使用羊副痘疹病毒(Parapoxvirus ovis；PPVO)及至少一種額外抗病毒藥之經B型肝炎病毒(HBV)感染之個體之組合療法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714665A1 (de) * 1977-04-01 1978-10-05 Mayr Anton Praeparat zur behandlung von herpes zoster und anderen herpes-infektionen, sowie verfahren zu seiner herstellung
US4360510A (en) * 1979-11-30 1982-11-23 Proctor Julian W Method for screening anti-tumor agents of the reticulo-endothelial stimulant class
US4663306A (en) * 1983-09-23 1987-05-05 Ribi Immunochem Research, Inc. Pyridine-soluble extract-refined detoxified endotoxin composition and use
DE3504940C2 (de) 1984-02-17 1997-11-06 Bayer Ag Multipotente Paramunitätsmediatoren, Verfahren zu ihrer Herstellung und diese Mediatoren enthaltende Arzneimittel
DE3816139A1 (de) * 1987-10-17 1989-04-27 Bayer Ag Verfahren zur herstellung von paramunitaetsinducern
DE4405841C1 (de) * 1994-02-23 1995-01-05 Mayr Anton Prof Dr Med Vet Dr Multipotente Paramunitätsinducer auf der Basis von Kombinationen von Pockenviruskomponenten, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
ATE203678T1 (de) * 1996-04-15 2001-08-15 Anton Prof Dr Med Vet Dr Mayr Verwendung von multipotenten paramunitätsinducern aus attenuierten, nicht-immunogenen pockenviren oder parapockenviren zur herstellung von arzneimitteln
DE19922407A1 (de) * 1999-05-14 2000-11-16 Bayer Ag Organ-, gewebs- und zellspezifisches Immuntherapeutikum für chronische virale Infektionen, sowie entzündliche, degenerative und proliferative Erkrankungen insbesondere der Leber sowie Krebs auf der Basis von rekombinantem Parapoxvirus
IL139593A (en) * 2000-11-09 2010-12-30 Biogem Optical Ltd Method for the detection of viable microorganisms

Also Published As

Publication number Publication date
NO20030081D0 (no) 2003-01-08
GB2383752A (en) 2003-07-09
GB2383752B (en) 2004-11-24
SE0300033D0 (sv) 2003-01-10
US20020076418A1 (en) 2002-06-20
FI20030038A (fi) 2003-03-10
NO20030081L (no) 2003-01-08
MA25765A1 (fr) 2003-04-01
PL360839A1 (en) 2004-09-20
HUP0303830A2 (hu) 2004-04-28
SK382003A3 (en) 2003-07-01
HK1054330A1 (en) 2003-11-28
JP5106736B2 (ja) 2012-12-26
BG107447A (bg) 2003-09-30
HUP0303830A3 (en) 2004-10-28
HRP20030097A2 (en) 2005-02-28
CN1452496B (zh) 2012-10-10
WO2002004019A2 (de) 2002-01-17
CA2415399A1 (en) 2003-01-08
HU227668B1 (en) 2011-11-28
IL153826A0 (en) 2003-07-31
LT5064B (lt) 2003-11-25
EP1303302B1 (de) 2009-10-14
LT2003008A (lt) 2003-07-25
WO2002004019A3 (de) 2002-08-01
LU90996B1 (en) 2003-01-08
AU2001285827B2 (en) 2006-11-30
HK1054330B (zh) 2005-07-15
SE0300033L (sv) 2003-03-10
CZ200372A3 (cs) 2003-05-14
GB0302629D0 (en) 2003-03-12
NZ523535A (en) 2004-12-24
DK200300014A (da) 2003-03-07
CN1452496A (zh) 2003-10-29
EP1303302A2 (de) 2003-04-23
AR028800A1 (es) 2003-05-21
CA2415399C (en) 2011-11-08
RU2003104522A (ru) 2004-06-27
AU8582701A (en) 2002-01-21
SI21171A (sl) 2003-10-31
JP2004502741A (ja) 2004-01-29
EE200300019A (et) 2004-10-15
US6632647B2 (en) 2003-10-14
MXPA03000278A (es) 2004-04-05

Similar Documents

Publication Publication Date Title
AT405939B (de) Verfahren zur inaktivierung von lipidumhüllten viren
DE60113512T2 (de) Veränderter stamm des modifizierten vaccinia-virus ankara (mva)
DE60314823T3 (de) Modifizierte variante des vaccinia ankara virus als impfstoff für neugeborene
Chauhan et al. Vesicular stomatitis virus infects resident cells of the central nervous system and induces replication-dependent inflammatory responses
Kris et al. Passive serum antibody causes temporary recovery from influenza virus infection of the nose, trachea and lung of nude mice.
Bennett et al. Studies on poxvirus infection in cats
LV12991B (en) Use of strains of the parapox ovis virus against organ fibrosis
Jayati et al. In vitro antiviral potential of Ocimum sanctum leaves extract against New Castle Disease Virus of poultry
AT406778B (de) Verfahren zur desintegration von nucleinsäuren und herstellung von qualitätsgesicherten biologischen produkten
Karagöz et al. Antiviral activity of Sanicula europaea L. extracts on multiplication of human parainfluenza virus type 2
EP1711204A1 (de) Monoparamunit tsinducer basierend auf attenuierten myxomavir en des kaninchens
JP5950964B2 (ja) 臓器線維形成に対するパラポックスウイルスｏｖｉｓ株の使用
EP1181381A2 (de) Organ-, gewebs- und zellspezifisches immuntherapeutikum für chronische virale infektionen, sowie entzündliche, degenerative und proliferative erkrankungen insbesondere der leber sowie krebs auf der basis von rekombinantem parapoxvirus
DE102005027956B4 (de) Hochattenuierte Poxvirusstämme, Verfahren zu ihrer Herstellung und deren Verwendung als Paramunitätsinducer oder zur Herstellung von Vektor-Vakzinen
Jortner et al. Experimental Chandipura virus infection in mice: I. Virus assay and light microscopic studies with emphasis on neuropathologic observations
CN109152804A (zh) 用于治疗纤维化的药物组合物
Trefry et al. Recombinant chimeric Horsepox Virus (TNX-801) is attenuated relative to Vaccinia Virus Strains in Human Primary Cell Lines and in Immunocompromised Mice
Oh et al. Different susceptibilities of skin to type 1 and type 2 herpes simplex viruses in newborn rabbits
Izawa et al. Herpesviral isolates related to Marek's disease virus from chicken and turkey kidney cell cultures
Oie et al. Studies on reovirus type 2: viral interference with UV-inactived virus
Walder et al. Cytomorphological changes during Nariva virus infection
DE102021001467A1 (de) Inocculation spezifischer Antigene von krankmachenden Agentien in Form von Tropfen oder Lyophilisat auf Augenschleimhaut oder Urogenitalschleimhaut zur Erzeugung der Immunität gegen diese Erkrankungen
Aoki et al. Analysis of the Inhibitory Effect of Canavanine on the Replication of Influenza RI/5+ Virus: II. Interaction of M Protein with the Plasma Membrane
Cheville et al. Cytopathic Changes in Lesions of a Pox Disease in Monkeys
DE2033946A1 (en) Live vaccine against vesicle eruption - (infectious pustular vulvovaginitis or bovine vesicular coital exanthema)in cattle