LV12342B - Progesterons išēmijas ārstēšanai vai mazināšanai - Google Patents

Progesterons išēmijas ārstēšanai vai mazināšanai Download PDF

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Publication number
LV12342B
LV12342B LVP-99-88A LV990088A LV12342B LV 12342 B LV12342 B LV 12342B LV 990088 A LV990088 A LV 990088A LV 12342 B LV12342 B LV 12342B
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LV
Latvia
Prior art keywords
ischemia
progesterone
pharmaceutical preparation
myocardial ischemia
preparation according
Prior art date
Application number
LVP-99-88A
Other languages
English (en)
Other versions
LV12342A (lv
Inventor
Howard L. Levine
William J. Bologna
Original Assignee
Columbia Laboratories (Bermuda) Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24987712&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LV12342(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Columbia Laboratories (Bermuda) Limited filed Critical Columbia Laboratories (Bermuda) Limited
Publication of LV12342A publication Critical patent/LV12342A/lv
Publication of LV12342B publication Critical patent/LV12342B/lv

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Claims (24)

  1. LV 12342 IZGUDROJUMA FORMULA 1. Farmaceitisks preparāts išēmijas ārstēšanai vai remisijai raksturīgs arto, ka ietver progesteronu.
  2. 2. Farmaceitisks preparāts saskaņā ar 1. punktu, r a k s t u r ī g s ar to, ka išēmija ir miokarda išēmija.
  3. 3. Farmaceitisks preparāts saskaņā ar 2. punktu, r a k s t u r ī g s ar to, ka išēmiju ir izsaukusi piepūle.
  4. 4. Farmaceitisks preparāts išēmijas remisijai estrogēna terapijas labvēlīgās ietekmes palielināšanai, r a k s t u r ī g s ar to, ka ietver progesteronu.
  5. 5. Farmaceitisks preparāts saskaņā ar 4. punktu, r a k s t u r ī g s ar to, ka išēmija ir miokarda išēmija.
  6. 6. Farmaceitisks preparāts saskaņā ar 5. punktu, r a k s t u r ī g s ar to, ka miokarda išēmiju ir izsaukusi piepūle.
  7. 7. Farmaceitisks preparāts saskaņā ar 6. punktu, r a k s t u r ī g s ar to, ka ietver strukturētu polikarbonskābes polimēru, kuru ievada sievietei vaginālā veidā ar zāļu formu.
  8. 8. Farmaceitisks preparāts saskaņā ar 7. punktu, r a k s t u r ī g s ar to, ka polimērs ir polikarbofīls.
  9. 9. Farmaceitisks preparāts saskaņā ar 7. punktu, r a k s t u r ī g s ar to, ka sieviete ir menopauzē.
  10. 10. Farmaceitisks preparāts ar 1. punktu, r a k s t u r ī g s ar to, ka to izmanto kad pacients ir pakļauts estrogēna terapijai.
  11. 11. Farmaceitisks preparāts saskaņā ar 2. punktu, r a k s t u r ī g s ar to, ka to izmanto kad pacients ir pakļauts estrogēna terapijai.
  12. 12. Farmaceitisks preparāts saskaņā ar 3. punktu, r a k s t u r ī g s ar to, ka to izmanto kad pacients ir pakļauts estrogēna terapijai.
  13. 13. Farmaceitisks preparāts saskaņā ar 11. punktu, r a k s t u r ī g s ar to, ka to izmanto kad estrogēna terapija domāta miokarda išēmijas ārstēšanai.
  14. 14. Farmaceitisks preparāts saskaņā ar 12. punktu, r a k s t u r ī g s ar to, ka to izmanto kad estrogēna terapija domāta piepūles izsauktas miokarda išēmijas ārstēšanai. 2
  15. 15. Farmaceitisks preparāts koronāro artēriju slimību ārstēšanai vai remisijai, r a k s t u r ī g s ar to, ka ietver progesteronu.
  16. 16. Farmaceitisks preparāts sirds-asinsvadu saslimšanas gadījumu ārstēšanai vai remisijai, r a k s t u r ī g s ar to, ka ietver progesteronu.
  17. 17. Progesterona izmantošana farmaceitiskas kompozīcijas izgatavošanai išemijas ārstēšanai vai remisijai.
  18. 18. Izmantošana saskaņā ar 17. punktu, kur išēmija ir miokarda išēmija.
  19. 19. Izmantošana saskaņā ar 18. punktu, kur miokarda išēmija ir piepūles izsauktā miokarda išēmija.
  20. 20. Progesterona izmantošana farmaceitiskas kompozīcijas izgatavošanai, kas domāta išēmijas remisijai izmantotās estrogēna terapijas labvēlīgās iedarbības saglabāšanai vai palielināšanai.
  21. 21. Izmantošana saskaņā ar 20. punktu, kur išēmija ir miokarda išēmija.
  22. 22. Izmantošana saskaņā ar 21. punktu, kur miokarda išēmija ir piepūles izsauktā miokarda išēmija.
  23. 23. Progesterona un strukturētā polikarbonskābes polimēra izmantošana išēmijas ārstēšanai vai remisijai domātas farmaceitiskas kompozīcijas pagatavošanai.
  24. 24. Izmantošana saskaņā ar 23. punktu, kur polimērs ir polikarboffls.
LVP-99-88A 1996-11-04 1999-05-28 Progesterons išēmijas ārstēšanai vai mazināšanai LV12342B (lv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/743,153 US5985861A (en) 1996-11-04 1996-11-04 Progesterone for treating or reducing ischemia
PCT/US1997/020923 WO1998019681A1 (en) 1996-11-04 1997-11-04 Progesterone for treating or reducing ischemia

Publications (2)

Publication Number Publication Date
LV12342A LV12342A (lv) 1999-09-20
LV12342B true LV12342B (lv) 2000-01-20

Family

ID=24987712

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-99-88A LV12342B (lv) 1996-11-04 1999-05-28 Progesterons išēmijas ārstēšanai vai mazināšanai

Country Status (27)

Country Link
US (2) US5985861A (lv)
EP (1) EP0956023B1 (lv)
KR (1) KR100434623B1 (lv)
CN (1) CN100341512C (lv)
AR (1) AR009407A1 (lv)
AT (1) ATE321558T1 (lv)
AU (1) AU715740C (lv)
BR (1) BR9710918A (lv)
CA (1) CA2270565C (lv)
DE (1) DE69735598T2 (lv)
DK (1) DK0956023T3 (lv)
ES (1) ES2262196T3 (lv)
GE (1) GEP20022630B (lv)
HK (1) HK1020534A1 (lv)
HU (1) HUP9904045A3 (lv)
IL (1) IL127455A (lv)
LV (1) LV12342B (lv)
MA (1) MA24391A1 (lv)
MY (1) MY121627A (lv)
NO (1) NO324278B1 (lv)
NZ (1) NZ335306A (lv)
PE (1) PE9899A1 (lv)
PT (1) PT956023E (lv)
RO (1) RO120607B1 (lv)
UA (1) UA66772C2 (lv)
WO (1) WO1998019681A1 (lv)
ZA (1) ZA979862B (lv)

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US6602487B1 (en) 1997-02-26 2003-08-05 Dimera Incorporated Methods and tests for producing and for inhibiting coronary artery vasospasms
US6056972A (en) * 1997-02-26 2000-05-02 Dimera, Llc Method for reducing coronary artery reactivity
US20040234606A1 (en) * 1997-09-12 2004-11-25 Levine Howard L. Localized vaginal delivery without detrimental blood levels
DE69819748T2 (de) 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
GB0107383D0 (en) * 2001-03-23 2001-05-16 Univ Edinburgh Lipid profile modulation
US20080182841A1 (en) * 2001-10-29 2008-07-31 Levine Howard L Vaginally administered anti-dysrhythmic agents for treating pelvic pain
US8425892B2 (en) 2001-10-29 2013-04-23 Columbia Laboratories, Inc. Extended, controlled-release pharmaceutical compositions using charged polymers
US20030114394A1 (en) * 2001-10-29 2003-06-19 Levine Howard L. Vaginally administered anti-dysrhythmic agents for treating pelvic pain
US7572780B2 (en) 2003-01-21 2009-08-11 Dimera, Incorporated Method and kit for reducing the symptoms of peripheral vascular disease
DE602004026173D1 (de) 2003-04-29 2010-05-06 Gen Hospital Corp Verfahren und vorrichtungen für die verzögerte freisetzung von mehreren arzneimitteln
DE102005027004B4 (de) * 2005-06-10 2020-03-19 Continental Automotive Gmbh Scheibenwaschvorrichtung
US8828981B2 (en) 2007-02-06 2014-09-09 George Creasy Progesterone for the treatment or prevention of spontaneous preterm birth
CA3016642A1 (en) 2008-02-04 2009-08-13 Ferring B.V. Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
LT2782584T (lt) 2011-11-23 2021-09-10 Therapeuticsmd, Inc. Natūralios kombinuotos pakaitinės hormonų terapijos kompozicijos ir gydymas
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
AU2015264003A1 (en) 2014-05-22 2016-11-17 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
KR20170040209A (ko) 2014-07-29 2017-04-12 쎄러퓨틱스엠디, 인코퍼레이티드 경피 크림
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US11512107B2 (en) 2018-09-07 2022-11-29 Trustees Of Dartmouth College Methods for assembly of tetracyclic compounds by stereoselective C9-C10 bond formation
WO2020051329A1 (en) * 2018-09-07 2020-03-12 Trustees Of Dartmouth College C19 scaffolds and steroids and methods of use and manufacture thereof
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1124906A1 (ru) * 1982-05-25 1984-11-23 Ивановский государственный медицинский институт им.А.С.Бубнова Способ коррекции ишемических повреждений консервированной донорской почки
ATE151286T1 (de) * 1983-11-14 1997-04-15 Columbia Lab Inc Bioadhäsive mittel
US5543150A (en) * 1993-09-15 1996-08-06 Columbia Laboratories, Inc. Method of progesterone delivery and affect thereof

Also Published As

Publication number Publication date
KR100434623B1 (ko) 2004-06-05
EP0956023A1 (en) 1999-11-17
PE9899A1 (es) 1999-02-08
AU5180198A (en) 1998-05-29
ATE321558T1 (de) 2006-04-15
NZ335306A (en) 2000-12-22
DE69735598T2 (de) 2006-12-28
CA2270565C (en) 2007-02-20
AU715740B2 (en) 2000-02-10
HK1020534A1 (en) 2000-05-12
GEP20022630B (en) 2002-02-25
MA24391A1 (fr) 1998-07-01
NO992140D0 (no) 1999-05-03
IL127455A (en) 2005-03-20
DK0956023T3 (da) 2006-08-07
IL127455A0 (en) 1999-10-28
HUP9904045A3 (en) 2000-11-28
CN1235549A (zh) 1999-11-17
US5985861A (en) 1999-11-16
RO120607B1 (ro) 2006-05-30
WO1998019681A1 (en) 1998-05-14
DE69735598D1 (de) 2006-05-18
ES2262196T3 (es) 2006-11-16
BR9710918A (pt) 2000-01-11
AU715740C (en) 2004-04-29
ZA979862B (en) 1998-05-25
NO324278B1 (no) 2007-09-17
PT956023E (pt) 2006-08-31
UA66772C2 (uk) 2004-06-15
NO992140L (no) 1999-05-04
US6054447A (en) 2000-04-25
LV12342A (lv) 1999-09-20
KR20000053056A (ko) 2000-08-25
CA2270565A1 (en) 1998-05-14
CN100341512C (zh) 2007-10-10
EP0956023B1 (en) 2006-03-29
MY121627A (en) 2006-02-28
AR009407A1 (es) 2000-04-12
HUP9904045A2 (hu) 2000-04-28

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