LV12039A - Triskartejie farmaceitiskie kompleksi kas iezimeti ar radioaktivo izotopu - Google Patents

Triskartejie farmaceitiskie kompleksi kas iezimeti ar radioaktivo izotopu

Info

Publication number
LV12039A
LV12039A LV970185A LV970185A LV12039A LV 12039 A LV12039 A LV 12039A LV 970185 A LV970185 A LV 970185A LV 970185 A LV970185 A LV 970185A LV 12039 A LV12039 A LV 12039A
Authority
LV
Latvia
Prior art keywords
labeled
radioactive isotope
pharmaceutical complexes
triple
triple pharmaceutical
Prior art date
Application number
LV970185A
Other languages
English (en)
Other versions
LV12039B (lv
Inventor
David Scott Edwards
Shuang Liu
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of LV12039A publication Critical patent/LV12039A/lv
Publication of LV12039B publication Critical patent/LV12039B/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LVP-97-185A 1995-04-03 1997-10-01 Trīskārtējie farmaceitiskie kompleksi, kas iezīmēti ar radioaktīvo izotopu LV12039B (lv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/415,908 US5744120A (en) 1993-03-30 1995-04-03 Ternary radiopharmaceutical complexes
PCT/US1996/004567 WO1996031243A1 (en) 1995-04-03 1996-04-03 Ternary radiopharmaceutical complexes

Publications (2)

Publication Number Publication Date
LV12039A true LV12039A (lv) 1998-05-20
LV12039B LV12039B (lv) 1998-10-20

Family

ID=23647726

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-97-185A LV12039B (lv) 1995-04-03 1997-10-01 Trīskārtējie farmaceitiskie kompleksi, kas iezīmēti ar radioaktīvo izotopu

Country Status (32)

Country Link
US (2) US5744120A (lv)
EP (2) EP1195168A3 (lv)
JP (1) JPH11503166A (lv)
KR (1) KR100417558B1 (lv)
CN (1) CN1080127C (lv)
AR (1) AR006077A1 (lv)
AT (1) ATE220335T1 (lv)
AU (1) AU719529B2 (lv)
BR (1) BR9608065A (lv)
CA (1) CA2216423C (lv)
CZ (1) CZ291658B6 (lv)
DE (1) DE69622267T2 (lv)
DK (1) DK0820312T3 (lv)
EA (1) EA000636B1 (lv)
EE (1) EE9700250A (lv)
ES (1) ES2179196T3 (lv)
HR (1) HRP960148A2 (lv)
HU (1) HU225674B1 (lv)
IL (1) IL117642A (lv)
LT (1) LT4391B (lv)
LV (1) LV12039B (lv)
MX (1) MX9707430A (lv)
NO (1) NO317177B1 (lv)
NZ (2) NZ308284A (lv)
PL (1) PL185325B1 (lv)
PT (1) PT820312E (lv)
SI (1) SI9620044B (lv)
SK (1) SK283276B6 (lv)
TW (1) TW503110B (lv)
UA (1) UA56127C2 (lv)
WO (1) WO1996031243A1 (lv)
ZA (1) ZA962672B (lv)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968476A (en) * 1992-05-21 1999-10-19 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
CA2363780C (en) * 1993-04-08 2003-01-07 Diatide, Inc. Radiolabeled compounds for thrombus imaging
US5855867A (en) * 1995-03-29 1999-01-05 The Curators Of The University Of Missouri Hydroxymethyl phosphine compounds for use as diagnostic and therapeutic pharmaceuticals and method of making same
US5739313A (en) 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
WO1997033627A2 (en) * 1996-03-13 1997-09-18 Du Pont Pharmaceuticals Company New ternary radiopharmaceutical complexes
US6416733B1 (en) * 1996-10-07 2002-07-09 Bristol-Myers Squibb Pharma Company Radiopharmaceuticals for imaging infection and inflammation
US20030124053A1 (en) * 1996-10-07 2003-07-03 Barrett John Andrew Radiopharmaceuticals for imaging infection and inflammation
US6403054B1 (en) 1997-05-28 2002-06-11 Bristol-Myers Squibb Pharma Company Ternary ligand complexes useful as radiopharmaceuticals
US7060251B1 (en) * 1997-09-08 2006-06-13 The General Hospital Corporation Imaging agents for early detection and monitoring of cardiovascular plaque
AU9307498A (en) * 1997-09-08 1999-03-29 General Hospital Corporation, The Imaging agents for early detection and monitoring of cardiovascular plaque
US6548663B1 (en) 1998-03-31 2003-04-15 Bristol-Myers Squibb Pharma Company Benzodiazepine vitronectin receptor antagonist pharmaceuticals
US6537520B1 (en) * 1998-03-31 2003-03-25 Bristol-Myers Squibb Pharma Company Pharmaceuticals for the imaging of angiogenic disorders
EA200001007A1 (ru) 1998-03-31 2001-04-23 Дюпон Фармасьютикалз Компани Фармацевтические препараты для визуализации ангиогенных расстройств
US6524553B2 (en) 1998-03-31 2003-02-25 Bristol-Myers Squibb Pharma Company Quinolone vitronectin receptor antagonist pharmaceuticals
WO1999051628A1 (en) * 1998-04-03 1999-10-14 Du Pont Pharmaceuticals Company Radiopharmaceuticals for imaging infection and inflammation and for imaging and treatment of cancer
CN1356913A (zh) 1998-12-18 2002-07-03 杜邦药品公司 玻连蛋白受体拮抗剂药物
US6511649B1 (en) 1998-12-18 2003-01-28 Thomas D. Harris Vitronectin receptor antagonist pharmaceuticals
US6569402B1 (en) 1998-12-18 2003-05-27 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
AU2371400A (en) 1998-12-18 2000-07-03 Du Pont Pharmaceuticals Company Vitronectin receptor antagonist pharmaceuticals
US6794518B1 (en) 1998-12-18 2004-09-21 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
US6346547B1 (en) 1999-02-08 2002-02-12 Checkpoint, Genetics, Inc. N-substituted amino acids, antioxidant pharmaceutical compositions containing n-substituted amino acids and methods for preventing cardiovascular diseases and/or preventing and/or treating antioxidant responsive diseases therewith
US6844425B1 (en) * 1999-02-24 2005-01-18 Mallinckrodt Inc. Combination of intercalating organometallic complexes and tumor seeking biomolecules for DNA cleavage and radiotherapy
IL145130A0 (en) * 1999-03-26 2002-06-30 Du Pont Pharm Co Method for localization of blood clots
US6808698B1 (en) 1999-03-26 2004-10-26 Bristol-Myers Squibb Pharma Company Method for localization of blood clots
US6806363B1 (en) 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
US7591995B2 (en) 1999-10-15 2009-09-22 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
MXPA02003772A (es) 1999-10-15 2005-04-28 Mayo Foundation Conjugados de cobalamina, utiles como agentes para obtencion de imagen y como agentes terapeuticos.
US6534038B2 (en) * 2000-04-07 2003-03-18 Bristol-Myers Squibb Pharma Company Ternary ligand complexes useful as radiopharmaceuticals
AU2001261728A1 (en) 2000-05-17 2001-11-26 Bristol-Myers Squibb Pharma Company Use of small molecule radioligands for diagnostic imaging
IL147629A0 (en) 2000-06-01 2002-08-14 Bristol Myers Squibb Pharma Co LACTAMS SUBSTITUTED BY CYCLIC SUCCINATES AS INHIBITORS OF Aβ PROTEIN PRODUCTION
WO2002036173A2 (en) * 2000-11-03 2002-05-10 Bristol-Myers Squibb Pharma Company Simultaneous dual isotope imaging of cardiac perfusion and cardiac inflammation
WO2002055111A2 (en) * 2000-11-27 2002-07-18 Bristol Myers Squibb Medical I Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
WO2002055112A2 (en) * 2001-01-09 2002-07-18 Bristol Myers Squibb Co Polypodal chelants for metallopharmaceuticals
US6517814B2 (en) 2001-01-09 2003-02-11 Bristol-Myers Squibb Pharma Company Macrocyclic chelants useful for metallopharmaceuticals
US6776977B2 (en) * 2001-01-09 2004-08-17 Bristol-Myers Squibb Pharma Company Polypodal chelants for metallopharmaceuticals
AU2002254000A1 (en) 2001-02-23 2002-09-12 Bristol-Myers Squibb Pharma Company Labeled macrophage scavenger receptor antagonists for imaging atherosclerosis and vulnerable plaque
HUP0401904A3 (en) * 2001-08-08 2009-01-28 Bristol Myers Squibb Pharma Co Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
US6838074B2 (en) 2001-08-08 2005-01-04 Bristol-Myers Squibb Company Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
US7317104B2 (en) 2003-06-13 2008-01-08 Bristol-Myers Squibb Pharma Company Chelants and macrocyclic metal complex radiopharmaceuticals thereof
US7319149B2 (en) * 2003-06-13 2008-01-15 Bristol-Myers Squibb Pharma Company Chelants and macrocyclic metal complex radiopharmaceuticals thereof
US20050106100A1 (en) * 2003-09-03 2005-05-19 Harris Thomas D. Compounds containing matrix metalloproteinase substrates and methods of their use
CN101252954A (zh) * 2005-06-30 2008-08-27 布里斯托尔-迈尔斯斯奎布药品公司 作为显像剂的酰肼偶联物
US8668900B2 (en) 2011-02-15 2014-03-11 Kuwait University Cancer-imaging agent and method of radioimaging using the same

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4248802A (en) * 1975-06-20 1981-02-03 Rhone-Poulenc Industries Catalytic hydroformylation of olefins
CA1300608C (en) * 1985-05-10 1992-05-12 Edward A. Deutsch 99 mtc (iii) myocardial imaging agents which are non-reducable in vivo
GB8624272D0 (en) * 1986-10-09 1986-11-12 Amersham Int Plc Cationic complexes of tc-99m
GB8711496D0 (en) * 1987-05-15 1987-06-17 Amersham Int Plc Tc-99m radiopharmaceuticals
EP0403524B1 (fr) * 1988-03-09 1993-02-10 Cis Bio International Preparation de complexes nitruro utilisables comme produits radiopharmaceutiques
GB8808414D0 (en) * 1988-04-11 1988-05-11 Amersham Int Plc Ligands & cationic complexes thereof with technetium-99m
US5002754A (en) * 1988-06-15 1991-03-26 University Of Cincinnati Technetium (III/II) imaging agents
US5066789A (en) * 1988-09-30 1991-11-19 Neorx Corporation Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages
GB8902362D0 (en) * 1989-02-03 1989-03-22 Amersham Int Plc Cationic complexes of technetium-99m
US5206370A (en) * 1989-02-24 1993-04-27 Johnson Matthey, Inc. Certain pyridyl hydrazines and hydrazides useful for protein labeling
US5792444A (en) * 1989-05-09 1998-08-11 The General Hospital Corporation Labeled chemotactic peptides to image focal sites of infection or inflammation
US4957728A (en) * 1989-05-19 1990-09-18 University Of Cincinnati Kit for preparing Tc (III)-99m myocardial imaging agents that are effective in humans
US4917879A (en) * 1989-05-19 1990-04-17 University Of Cincinnati 99MTC(III) myocardial imaging agents that are effective in humans
US5384309A (en) * 1989-07-17 1995-01-24 Genentech, Inc. Cyclized peptides and their use as platelet aggregation inhibitors
GB8919488D0 (en) * 1989-08-29 1989-10-11 Amersham Int Plc New cores for technetium radiopharmaceuticals
DE122005000028I2 (de) * 1989-10-30 2007-08-16 Rotop Pharmaka Ag Kit (nichtradioaktive Vorstufe) zur Herstellung einer enantiomeren Form des Nierenfunktionsdiagnostikums Technetium-99m-Mercaptoacetyltriglycin (99m-Tc-MAG-3) und Verfahren zur Herstellung des Kits
FR2664166A1 (fr) * 1990-07-04 1992-01-10 Cis Bio Int Procede de preparation de complexes nitruro de metaux de transition utilisables comme produits radiopharmaceutiques ou pour la synthese de nouveaux produits radiopharmaceutiques.
US5112594A (en) * 1991-04-04 1992-05-12 Mallinckrodt Medical, Inc. Kit for preparing a technetium-99m myocardial imaging agent
JPH06509551A (ja) * 1991-04-05 1994-10-27 ジェネンテク，インコーポレイテッド Ｇｐ　ＩＩ↓ｂＩＩＩ↓ａに対する高い特異性を有する血小板凝集阻害剤
FR2679452B1 (fr) * 1991-07-22 1993-11-12 Cis Bio International Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation.
US5336482A (en) * 1991-12-05 1994-08-09 The Du Pont Merck Pharmaceutical Company Technetium-99m complexes with N-substituted 3-hydroxy-4-pyridinones
US5300280A (en) * 1992-02-14 1994-04-05 Mallinckrodt Medical, Inc. Stabilized radiopharmaceutical kits
GB9209641D0 (en) 1992-05-02 1992-06-17 Johnson Matthey Plc Improvements in radiolabelling
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
CA2158249A1 (en) * 1993-03-31 1994-10-13 James W. Brodack Radiopharmaceutical formulations having non-stannous reductants
IT1261386B (it) * 1993-12-21 1996-05-20 Sorin Biomedica Spa Peptidi modificati con gruppo fosfinico per la marcatura con 99m-tc e 186-188-re o agenti paramagnetici.
US5521156A (en) * 1994-02-03 1996-05-28 Merrell Pharmaceuticals Inc. Cyclic neurokinin A antagonists
US8019150B2 (en) 2007-10-11 2011-09-13 Kwe International, Inc. Color quantization based on desired upper bound for relative quantization step

Also Published As

Publication number Publication date
HUP9801949A3 (en) 2000-09-28
EP0820312A1 (en) 1998-01-28
NO317177B1 (no) 2004-09-06
MX9707430A (es) 1997-12-31
EP1195168A3 (en) 2007-05-30
DK0820312T3 (da) 2002-09-02
PT820312E (pt) 2002-10-31
CZ291658B6 (cs) 2003-04-16
CA2216423C (en) 2004-03-09
TW503110B (en) 2002-09-21
LV12039B (lv) 1998-10-20
DE69622267D1 (de) 2002-08-14
EA199700291A1 (ru) 1998-04-30
CN1080127C (zh) 2002-03-06
EA000636B1 (ru) 1999-12-29
ES2179196T3 (es) 2003-01-16
PL185325B1 (pl) 2003-04-30
NZ308284A (en) 1999-05-28
LT97157A (en) 1998-05-25
NO974549L (no) 1997-12-02
NO974549D0 (no) 1997-10-02
WO1996031243A1 (en) 1996-10-10
HRP960148A2 (en) 1997-10-31
EE9700250A (et) 1998-04-15
KR100417558B1 (ko) 2004-03-19
SK132997A3 (en) 1999-01-11
JPH11503166A (ja) 1999-03-23
UA56127C2 (uk) 2003-05-15
LT4391B (lt) 1998-10-26
IL117642A0 (en) 1996-07-23
ATE220335T1 (de) 2002-07-15
AR006077A1 (es) 1999-08-11
DE69622267T2 (de) 2003-02-20
EP1195168A2 (en) 2002-04-10
SK283276B6 (sk) 2003-05-02
AU5787496A (en) 1996-10-23
SI9620044B (sl) 1999-02-28
AU719529B2 (en) 2000-05-11
US5744120A (en) 1998-04-28
EP0820312A4 (en) 1998-03-18
SI9620044A (sl) 1998-06-30
US6010679A (en) 2000-01-04
BR9608065A (pt) 1999-06-29
HU225674B1 (en) 2007-06-28
CN1185116A (zh) 1998-06-17
IL117642A (en) 2003-04-10
KR19980703560A (ko) 1998-11-05
CA2216423A1 (en) 1996-10-10
PL322583A1 (en) 1998-02-02
HUP9801949A2 (hu) 1999-02-01
CZ302797A3 (cs) 1998-11-11
EP0820312B1 (en) 2002-07-10
NZ333276A (en) 2000-07-28
ZA962672B (en) 1997-10-03

Similar Documents

Publication Publication Date Title
LV12039A (lv) Triskartejie farmaceitiskie kompleksi kas iezimeti ar radioaktivo izotopu
DE68917107D1 (de) Stabilisierte Sucralosekomplexe.
LV12044A (lv) Stabili reagenti ar radioaktivu izotopu iezimetu farmaceitisku preparatu iegusanai
NO954146D0 (no) Belagte farmasöytiske preparater
DE69310243D1 (de) Warenabrechnungsanlage
DE3480599D1 (de) 1-hydroxypyrid-2-on-derivate enthaltende pharmazeutische zubereitungen.
NO179941C (no) Farmasöytisk forbindelse
DE69304348D1 (de) Münzdetektor
FR2686693B1 (fr) Detecteur magnetique.
DE69309972T2 (de) Warenabrechnungsanlage
DE69324431T2 (de) Hartkapseln
NO932684L (no) Svingplate-sperremekanisme
NO893129D0 (no) Brems for maalebaand.
NL194827B (nl) Thieno-triazolo-diazepinederivaten en farmaceutische preparaten die een dergelijk derivaat bevatten.
NO934145D0 (no) Farmas!ytiske forbindelser
FR2692071B1 (fr) Tourne-disque.
KR950704292A (ko) 약학적 활성을 가진 이환식 화합물(Bicycylic Compounds with Pharmaceutical Activity)
DE69420295T2 (de) Eine Bandkassette
DE69310263T2 (de) Plattenkassette
KR950034457U (ko) ㄱ 형 완금
FI940287A0 (fi) Järjestely tietokonejärjestelmää varten
NO307284B1 (no) Medisiner for kardial insuffisiens
FI934317A0 (fi) Farmaceutiska sammansaettningar, vilka innehaoller ej-joniska ytaktiva aemnen
NL193607B (nl) Farmaceutisch preparaat dat N-acetylcysteïne bevat.
FI950069A0 (fi) Heksadentaattiligandit, jotka ovat käyttökelpoisia radiografisissa kuvausaineissa