AU2001261728A1 - Use of small molecule radioligands for diagnostic imaging - Google Patents

Use of small molecule radioligands for diagnostic imaging

Info

Publication number
AU2001261728A1
AU2001261728A1 AU2001261728A AU6172801A AU2001261728A1 AU 2001261728 A1 AU2001261728 A1 AU 2001261728A1 AU 2001261728 A AU2001261728 A AU 2001261728A AU 6172801 A AU6172801 A AU 6172801A AU 2001261728 A1 AU2001261728 A1 AU 2001261728A1
Authority
AU
Australia
Prior art keywords
radioligands
small molecule
diagnostic imaging
diagnostic
imaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001261728A
Inventor
Richard E. Olson
Dietmar A. Seiffert
Lorin A. Thompson
Robert Zaczek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Pharma Co
Original Assignee
DuPont Merck Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DuPont Merck Pharmaceutical Co filed Critical DuPont Merck Pharmaceutical Co
Publication of AU2001261728A1 publication Critical patent/AU2001261728A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0468Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2001261728A 2000-05-17 2001-05-17 Use of small molecule radioligands for diagnostic imaging Abandoned AU2001261728A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20468500P 2000-05-17 2000-05-17
US60/204,685 2000-05-17
PCT/US2001/016009 WO2001087354A2 (en) 2000-05-17 2001-05-17 Use of small molecule radioligands for diagnostic imaging

Publications (1)

Publication Number Publication Date
AU2001261728A1 true AU2001261728A1 (en) 2001-11-26

Family

ID=22758997

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001261728A Abandoned AU2001261728A1 (en) 2000-05-17 2001-05-17 Use of small molecule radioligands for diagnostic imaging

Country Status (3)

Country Link
US (2) US6878363B2 (en)
AU (1) AU2001261728A1 (en)
WO (1) WO2001087354A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6737038B1 (en) * 1998-11-12 2004-05-18 Bristol-Myers Squibb Company Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging
US20020115717A1 (en) * 2000-07-25 2002-08-22 Francine Gervais Amyloid targeting imaging agents and uses thereof
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
CH698246B1 (en) * 2001-12-20 2009-06-30 Hoffmann La Roche Test to identify inhibitors of beta secretases.
EP1482988A1 (en) * 2002-02-12 2004-12-08 Vistatec York Limited METHOD OF RADIO−LABELLING BIOMOLECULES
US20040223912A1 (en) * 2003-05-07 2004-11-11 Montalto Michael Christopher Compositions and methods for non-invasive imaging of soluble beta-amyloid
EP1631561B1 (en) 2003-05-07 2010-08-18 General Electric Company Compositions and methods for non-invasive imaging of soluble beta-amyloid
US20070053831A1 (en) * 2003-05-20 2007-03-08 Barrio Jorge R Methods for binding agents to b-amyloid plaques
US20050214222A1 (en) * 2004-02-13 2005-09-29 Mckinnon Stuart J In vivo imaging of amyloid plaques in glaucoma using intravenous injectable dyes
WO2008118122A2 (en) * 2006-05-08 2008-10-02 Molecular Neuroimaging, Llc Compounds and amyloid probes thereof for therapeutic and imaging uses
CA2967254C (en) 2008-02-29 2019-03-26 Lantheus Medical Imaging, Inc. Contrast agents for applications including imaging cancer
US20100178245A1 (en) * 2009-01-13 2010-07-15 Arnsdorf Morton F Biocompatible Microbubbles to Deliver Radioactive Compounds to Tumors, Atherosclerotic Plaques, Joints and Other Targeted Sites
KR102438133B1 (en) 2010-02-08 2022-08-31 랜티우스 메디컬 이메징, 인크. Methods and apparatus for synthesizing imaging agents, and intermediates thereof
JP5863797B2 (en) * 2010-08-16 2016-02-17 コグノプティックス, インコーポレイテッド Device for detecting amyloid protein
TWI530489B (en) 2011-03-22 2016-04-21 必治妥美雅史谷比公司 Bis(fluoroalkyl)-1,4-benzodiazepinone compounds
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
CN104968648A (en) 2012-09-21 2015-10-07 百时美施贵宝公司 Prodrugs of 1, 4-benzodiazepinone compounds
EP2897960B1 (en) 2012-09-21 2016-08-03 Bristol-Myers Squibb Company Tricyclic heterocyclic compounds as notch inhibitors
US9133126B2 (en) 2012-09-21 2015-09-15 Bristol-Myers Squibb Company Fluoroalkyl dibenzoazepinone compounds
TWI614238B (en) 2012-09-21 2018-02-11 必治妥美雅史谷比公司 Bis(fluoroalkyl)-1,4-benzodiazepinone compounds and prodrugs thereof
EP2897954B1 (en) 2012-09-21 2016-10-26 Bristol-Myers Squibb Company Fluoroalkyl-1,4-benzodiazepinone compounds
CN104797569A (en) 2012-09-21 2015-07-22 百时美施贵宝公司 Substituted 1,5-benzodiazepinone compounds
CN104822665A (en) 2012-09-21 2015-08-05 百时美施贵宝公司 Fluoroalkyl and fluorocycloalkyl 1,4-benzodiazepinone compounds as notch inhibitors
CN104854097A (en) 2012-09-21 2015-08-19 百时美施贵宝公司 N-substituted bis(fluoroalkyl)-1,4-benzodiazepinone compounds
JP2015534554A (en) 2012-09-21 2015-12-03 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company Alkyl, fluoroalkyl-1,4-benzodiazepinone compounds
JP2016515625A (en) 2013-04-04 2016-05-30 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company Combination therapy to treat proliferative diseases
CN113634240B (en) * 2021-08-26 2023-10-27 宏葵生物(中国)股份有限公司 Fluorescent magnetic composite nanofiber, preparation method and application thereof

Family Cites Families (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3828025A (en) * 1970-11-04 1974-08-06 Pfizer Phosphono substituted acylpenicillins
US4859777A (en) 1981-07-01 1989-08-22 Eastman Kodak Company Terpyridine chelating agents
US4666829A (en) 1985-05-15 1987-05-19 University Of California Polypeptide marker for Alzheimer's disease and its use for diagnosis
DE3688613T2 (en) * 1985-11-18 1994-01-13 Access Pharma Inc POLYCHELING SUBSTANCES FOR IMAGING AND SPECTRAL INCREASING (AND SPECTRAL SHIFT).
CA1305160C (en) 1985-12-23 1992-07-14 Paul Louis Bergstein Ether isonitriles and radiolabeled complexes thereof
US5567411A (en) 1986-11-10 1996-10-22 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Dendritic amplifier molecules having multiple terminal active groups stemming from a benzyl core group
US5252317A (en) 1986-11-10 1993-10-12 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Amplifier molecules for diagnosis and therapy derived from 3,5-bis[1-(3-amino-2,2-bis (aminomethyl)-propyl) oxymethyl] benzoic acid
US5064956A (en) 1987-06-24 1991-11-12 The Dow Chemical Company Process for preparing mono-n-alkylated polyazamacrocycles
US5087440A (en) * 1989-07-31 1992-02-11 Salutar, Inc. Heterocyclic derivatives of DTPA used for magnetic resonance imaging
JPH0374328A (en) * 1989-08-04 1991-03-28 Warner Lambert Co Antagonist for central cholecystokinin having pharmaceutical activity
GB8923843D0 (en) 1989-10-23 1989-12-13 Salutar Inc Compounds
US5679810A (en) 1990-01-19 1997-10-21 Salutar, Inc. Linear oligomeric polychelant compounds
GB9006977D0 (en) 1990-03-28 1990-05-23 Nycomed As Compositions
WO1992017215A1 (en) 1990-03-28 1992-10-15 Nycomed Salutar, Inc. Contrast media
US5434050A (en) * 1991-08-13 1995-07-18 Regents Of The University Of Minnesota Labelled β-amyloid peptide and methods of screening for Alzheimer's disease
JP2556988Y2 (en) * 1991-08-28 1997-12-08 日本ヒューレット・パッカード株式会社 Terminal device for electrical connection
US5766846A (en) 1992-07-10 1998-06-16 Athena Neurosciences Methods of screening for compounds which inhibit soluble β-amyloid peptide production
DE69330959T2 (en) * 1992-07-29 2002-04-11 Merck Sharp & Dohme benzodiazepine derivatives
US5283241A (en) * 1992-08-28 1994-02-01 Merck & Co., Inc. Benzo-fused lactams promote release of growth hormone
MX9308016A (en) * 1992-12-22 1994-08-31 Lilly Co Eli HUMAN IMMUNODEFICIENCY VIRUS PROTEASE INHIBITING COMPOUNDS, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATION CONTAINING THEM.
US5760191A (en) 1993-02-05 1998-06-02 Nycomed Imaging As Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
EP0692978A4 (en) 1993-03-31 1998-05-06 Mallinckrodt Medical Inc Radiopharmaceutical formulations having non-stannous reductants
AU7102394A (en) * 1993-06-09 1995-01-03 Smithkline Beecham Corporation Bicyclic fibrinogen antagonists
ZA945719B (en) 1993-08-09 1996-02-01 Lilly Co Eli Identification and use of protease inhibitors
US5459954A (en) 1993-08-31 1995-10-24 Admotion Corporation Advertising display method and apparatus
KR100316865B1 (en) 1993-10-01 2002-11-29 메렐 파마슈티칼스 인크. Inhibitors of β-amyloid protein production
US5417959A (en) 1993-10-04 1995-05-23 Mallinckrodt Medical, Inc. Functionalized aza-crytand ligands for diagnostic imaging applications
US5426185A (en) * 1993-11-22 1995-06-20 Merck & Co., Inc. Antiarrhythmic benzodiazepines
WO1996004254A2 (en) * 1994-07-29 1996-02-15 Fujisawa Pharmaceutical Co., Ltd. Benzodiazepine derivatives
US5661161A (en) * 1994-09-29 1997-08-26 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5520904A (en) 1995-01-27 1996-05-28 Mallinckrodt Medical, Inc. Calcium/oxyanion-containing particles with a polymerical alkoxy coating for use in medical diagnostic imaging
EP0727225A3 (en) 1995-02-14 1997-01-15 Sonus Pharma Inc Compositions and methods for directed ultrasound imaging
US5672598A (en) 1995-03-21 1997-09-30 The Procter & Gamble Company Lactam-containing hydroxamic acids
US5856326A (en) * 1995-03-29 1999-01-05 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5578629A (en) * 1995-03-29 1996-11-26 Merck & Co., Inc. Benzamide-containing inhibitors of farnesyl-protein transferase
CA2220055C (en) * 1995-05-08 2001-04-24 Pfizer Inc. Dipeptides which promote release of growth hormone
US5710171A (en) * 1995-05-24 1998-01-20 Merck & Co., Inc. Bisphenyl inhibitors of farnesyl-protein transferase
US5756528A (en) * 1995-06-06 1998-05-26 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5801228A (en) 1995-06-07 1998-09-01 Nycomed Imaging As Polymeric contrast agents for medical imaging
EP0761680A3 (en) * 1995-09-12 1999-05-06 Ono Pharmaceutical Co., Ltd. Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity
US5879659A (en) * 1996-03-13 1999-03-09 Dupont Pharmaceuticals Company Ternary radiopharmaceutical complexes
US5919785A (en) * 1996-04-03 1999-07-06 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5852010A (en) * 1996-04-03 1998-12-22 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5891889A (en) * 1996-04-03 1999-04-06 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5859012A (en) * 1996-04-03 1999-01-12 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5885995A (en) * 1996-04-03 1999-03-23 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5869682A (en) * 1996-04-03 1999-02-09 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5804161A (en) 1996-05-14 1998-09-08 Nycomed Salutar Inc. Contrast agents
US5703129A (en) * 1996-09-30 1997-12-30 Bristol-Myers Squibb Company 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of β-amyloid protein production
ID21956A (en) 1996-11-22 1999-08-19 Elan Pharm Inc ACID N- (ARIL AND OR HETEROARILASETHL) AMINO ESTER, COMPOSITION OF THE PHARMACY CONTAINING IT, AND THE METHODS TO SPRIT THE BETHA-AMILOID PEPTIDES AND OR SYNTHESIAN COMPOSITION CONTAINING IT, AND THE METHODS TO SPRIT THE BETHA-AMILOID PEPTIDES AND OR SYNTHESIAN COMPOSITION THAT CONTAINS IT, AND THE METHODS TO SPRIT THE RELEASE OF BETHA-AMILOID PEPTIDES AND OR THE SYNTHESIA USING THE COMPOUND.
EP0942923A2 (en) 1996-11-22 1999-09-22 Elan Pharmaceuticals, Inc. N-(ARYL/HETEROARYL) AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
PL334516A1 (en) 1996-11-22 2000-02-28 Elan Pharm Inc N-(aryl/heteroaryl/alkylacetyl)amino cid amides, pharmaceutic agent containing them and method of inhibiting eduction and/or synthesis of beta-amyloid peptide using such compounds
AR016751A1 (en) 1996-11-22 2001-08-01 Athena Neurosciences Inc METHOD FOR INHIBITING THE RELEASE OF THE BETA-AMYLOID PEPTIDE IN A CELL, PHARMACEUTICAL COMPOSITION AND USEFUL COMPOUNDS IN THIS METHOD
EP0944580A2 (en) 1996-11-22 1999-09-29 Elan Pharmaceuticals, Inc. N-(aryl/heteroaryl) amino acid esters, pharmaceutical compositions, and methods for inhibiting beta-amyloid peptide release and/or its synthesis
WO1998028268A2 (en) 1996-12-23 1998-07-02 Elan Pharmaceuticals, Inc. CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS
FR2760024B1 (en) 1997-02-21 1999-05-14 Centre Nat Rech Scient PROCESS FOR CHARACTERIZING DUPLEX OF NUCLEIC ACID
HRP980093A2 (en) 1997-02-28 1998-12-31 Lilly Co Eli Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting "beta"-amyloid peptide release and/or its synthesis by use of such compounds
GB9721373D0 (en) 1997-10-08 1997-12-10 Johnson & Son Inc S C Improvements in liquid compositions
US5836690A (en) 1997-12-17 1998-11-17 Ultimate Environmental Mixing, Inc. Rotatable mixing head having sealed bearings
WO1999067219A1 (en) 1998-06-22 1999-12-29 Elan Pharmaceuticals, Inc. Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
CA2325388A1 (en) 1998-06-22 1999-12-29 Elan Pharmaceuticals, Inc. Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
WO1999067221A1 (en) 1998-06-22 1999-12-29 Elan Pharmaceuticals, Inc. Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
AU4710499A (en) 1998-06-22 2000-01-10 Elan Pharmaceuticals, Inc. Cyclic amino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use ofsuch compounds
HRP990246A2 (en) 1998-08-07 2000-06-30 Du Pont Pharm Co Succinoylamino benzodiazepines as inhibitors of a beta protein production
WO2000024392A1 (en) 1998-10-26 2000-05-04 Sumitomo Pharmaceuticals Company, Limited β-AMYLOID FORMATION INHIBITORS
GB9823499D0 (en) 1998-10-27 1998-12-23 Proman Chem Ltd Barrier coatings
DE19851456A1 (en) 1998-11-09 2000-05-11 Bosch Gmbh Robert Device and method for moving parts
WO2000028331A1 (en) * 1998-11-12 2000-05-18 Du Pont Pharmaceuticals Company Use of radioligands to screen inhibitors of amyloid-beta peptide production
WO2000038618A2 (en) 1998-12-24 2000-07-06 Du Pont Pharmaceuticals Company SUCCINOYLAMINO BENZODIAZEPINES AS INHIBITORS OF Aβ PROTEIN PRODUCTION
NZ534876A (en) * 1999-02-10 2006-02-24 Elan Pharm Inc Human beta-secretase enzyme, inhibitors and their compositions and uses
AT409441B (en) 1999-07-16 2002-08-26 Koenig Maschinen Gmbh DEVICE FOR MOLDING A CONTINUOUS DUMP BAND FROM AN UNFORMED Dough
AU779120B2 (en) 1999-08-02 2005-01-06 Harris Interactive, Inc. System for protecting information over the internet
US6494531B1 (en) 1999-08-04 2002-12-17 Hoon Y. Kim Vehicle seat for reversible occupant travel
GB9918586D0 (en) 1999-08-07 1999-10-06 British Gas Plc Compact reactor
DE19937511A1 (en) 1999-08-09 2001-02-15 Rainer Hartmann Procedure for adjusting parabolic antennas
US6171262B1 (en) 1999-08-11 2001-01-09 Creative Plastic Technology, Llc Retractable blood collection device
MXPA02001813A (en) 1999-09-13 2004-03-19 Bristol Myers Squibb Pharma Co Hydroxyalkanoyl aminolactams and related structures as inhibitors of a beta protein production.
CA2387535A1 (en) 1999-10-13 2001-04-19 Banyu Pharmaceutical Co., Ltd. Substituted imidazolidinone derivatives
AU2001239791A1 (en) 2000-02-17 2001-08-27 Du Pont Pharmaceuticals Company Succinoylamino carbocycles and heterocycles as inhibitors of abeta protein production
EP1267906A1 (en) * 2000-03-28 2003-01-02 Bristol-Myers Squibb Pharma Company Lactams as inhibitors of a-beta protein production
CA2404314A1 (en) 2000-03-31 2001-10-11 Lorin Andrew Thompson Succinoylamino heterocycles as inhibitors of a.beta. protein production
MXPA02009755A (en) 2000-04-03 2003-03-27 Bristol Myers Squibb Pharma Co CYCLIC LACTAMS AS INHIBITORS OF Abeta PROTEIN PRODUCTION.
CN1434803A (en) 2000-04-03 2003-08-06 布里斯托尔-迈尔斯斯奎布药品公司 Cyclic lactams as inhibitors os A-alpha protein production
CA2404273A1 (en) 2000-04-11 2001-10-18 Bristol-Myers Squibb Pharma Company Substituted lactams as inhibitors of a.beta. protein production
AU783857B2 (en) * 2000-06-01 2005-12-15 Bristol-Myers Squibb Pharma Company Lactams substituted by cyclic succinates as inhibitors of a beta protein production

Also Published As

Publication number Publication date
US20050129612A1 (en) 2005-06-16
US6878363B2 (en) 2005-04-12
WO2001087354A3 (en) 2002-08-22
US20020159947A1 (en) 2002-10-31
WO2001087354A2 (en) 2001-11-22

Similar Documents

Publication Publication Date Title
AU2001261728A1 (en) Use of small molecule radioligands for diagnostic imaging
AU2001227815A1 (en) Chemically specific imaging of tissue
AU2002220053A1 (en) Integrated sensor holder for dental imaging
AU2002331850A1 (en) Methods of endobronchial diagnosis using imaging
AU2002357155A1 (en) Endoscopic imaging system
AU1769101A (en) Graphical user interface for in-vivo imaging
EP1126287A3 (en) Ultrasonic diagnosis apparatus
AU2001273505A1 (en) Single-use radiological imaging aid
AU2001280061A1 (en) Measurement of critical dimensions using x-rays
AU2001288462A1 (en) Medical instrument
AU2001232360A1 (en) Medical instrument
AU4082801A (en) Imaging apparatus
AU2002251739A1 (en) Activatable imaging probes
AU2002346086A1 (en) Diagnostic imaging tabletop
AUPQ886100A0 (en) Diagnostic test
AU2002357002A1 (en) Diagnostic sensing apparatus
AU2002245169A1 (en) Fullerene (c60)-based x-ray contrast agent for diagnostic imaging
AU5920899A (en) Imaging of surgical biopsies
AU2001276498A1 (en) Apparatus for diagnostic assays
AU2001236592A1 (en) Methods for diagnosis of alzheimer's disease
AU2000268695A1 (en) Imaging apparatus
AU2001264631A1 (en) Medical instrument
AU2002228725A1 (en) Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds
AU2002239244A1 (en) Apparatus for the transillumination imaging of teeth
AU2003283648A1 (en) Compounds as radioligands for the diagnosis of disease