KR950704292A - 약학적 활성을 가진 이환식 화합물(Bicycylic Compounds with Pharmaceutical Activity) - Google Patents

약학적 활성을 가진 이환식 화합물(Bicycylic Compounds with Pharmaceutical Activity)

Info

Publication number
KR950704292A
KR950704292A KR1019950702382A KR19950702382A KR950704292A KR 950704292 A KR950704292 A KR 950704292A KR 1019950702382 A KR1019950702382 A KR 1019950702382A KR 19950702382 A KR19950702382 A KR 19950702382A KR 950704292 A KR950704292 A KR 950704292A
Authority
KR
South Korea
Prior art keywords
bicycylic
compounds
pharmaceutical activity
pharmaceutical
activity
Prior art date
Application number
KR1019950702382A
Other languages
English (en)
Other versions
KR100326968B1 (ko
Inventor
머빈 톰슨
존 모리스 에반스
닐 업톤
와이 느고르 찬
퀵 키옹 봉
로버트 니콜라스 윌레트
Original Assignee
스미스클라인 비참 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929225964A external-priority patent/GB9225964D0/en
Priority claimed from GB929225956A external-priority patent/GB9225956D0/en
Priority claimed from GB929225881A external-priority patent/GB9225881D0/en
Priority claimed from GB929225957A external-priority patent/GB9225957D0/en
Priority claimed from GB929225963A external-priority patent/GB9225963D0/en
Application filed by 스미스클라인 비참 코포레이션 filed Critical 스미스클라인 비참 코포레이션
Publication of KR950704292A publication Critical patent/KR950704292A/ko
Application granted granted Critical
Publication of KR100326968B1 publication Critical patent/KR100326968B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019950702382A 1992-12-11 1993-12-08 약학적 활성을 가진 이환식 화합물 KR100326968B1 (ko)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
GB929225964A GB9225964D0 (en) 1992-12-11 1992-12-11 Novel treatment
GB9225957.1 1992-12-11
GB929225956A GB9225956D0 (en) 1992-12-11 1992-12-11 Novel treatment
GB929225881A GB9225881D0 (en) 1992-12-11 1992-12-11 Novel treatment
GB9225956.3 1992-12-11
GB9225963.9 1992-12-11
GB9225881.3 1992-12-11
GB9225964.7 1992-12-11
GB929225957A GB9225957D0 (en) 1992-12-11 1992-12-11 Novel treatment
GB929225963A GB9225963D0 (en) 1992-12-11 1992-12-11 Novel treatment
PCT/GB1993/002512 WO1994013656A1 (en) 1992-12-11 1993-12-08 Bicyclic compounds with pharmaceutical activity

Publications (2)

Publication Number Publication Date
KR950704292A true KR950704292A (ko) 1995-11-17
KR100326968B1 KR100326968B1 (ko) 2002-07-27

Family

ID=27517163

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950702382A KR100326968B1 (ko) 1992-12-11 1993-12-08 약학적 활성을 가진 이환식 화합물

Country Status (9)

Country Link
US (1) US5908860A (ko)
EP (1) EP0673373A1 (ko)
JP (2) JPH08505132A (ko)
KR (1) KR100326968B1 (ko)
CN (3) CN1066625C (ko)
AU (1) AU679475B2 (ko)
CA (1) CA2151515A1 (ko)
NZ (1) NZ258610A (ko)
WO (1) WO1994013656A1 (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69518322T2 (de) * 1994-06-10 2001-02-15 Smithkline Beecham Plc C-4 amid substituierte verbindungen und deren verwendung als therapeutische mittel
GB9411635D0 (en) 1994-06-10 1994-08-03 Smithkline Beecham Plc Novel treatment
DE69524871T2 (de) * 1994-06-10 2002-08-22 Smithkline Beecham Plc Benzopyrans und deren verwendung als therapeutische mittel
US5574049A (en) * 1994-07-22 1996-11-12 Sandoz Ltd. 2,2-dialkyl- and 2,2-dialkyl-3,4-dihydro-3-hydroxy-2H-1-benzopyrans
GB9813949D0 (en) * 1998-06-29 1998-08-26 Smithkline Beecham Plc Novel compounds
RU2316317C2 (ru) * 2001-12-28 2008-02-10 Эм-Джи-Ай Джи-Пи, Инк. Составленные на основе воды фармацевтические композиции водорастворимых пролекарств пропофола
US7576094B2 (en) * 2004-12-13 2009-08-18 Eli Lilly And Company Spiro derivatives as lipoxygenase inhibitors
US20140011773A1 (en) 2012-07-03 2014-01-09 Proximagen Limited Pro-drug Compounds
GB201304814D0 (en) * 2013-03-15 2013-05-01 Proximagen Ltd Pro-drug compounds
GB201322934D0 (en) * 2013-12-23 2014-02-12 Proximagen Ltd Prodrug compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126311B1 (en) * 1983-05-18 1989-09-13 Beecham Group Plc Benzopyran derivatives.
DE3682331D1 (de) * 1985-06-08 1991-12-12 Beecham Group Plc Pyrano(3,2-c)pyridinderivate, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
US5021432A (en) * 1988-04-26 1991-06-04 Yoshitomi Pharmaceutical Industries, Ltd. Benzopyran compound and its pharmaceutical use
US5624954A (en) * 1991-06-13 1997-04-29 Smithkline Beecham P.L.C. Benzo- and pyridopyran derivatives having anxiolytic and anti-convulsant activity

Also Published As

Publication number Publication date
KR100326968B1 (ko) 2002-07-27
AU679475B2 (en) 1997-07-03
CN1270169A (zh) 2000-10-18
CN1066625C (zh) 2001-06-06
EP0673373A1 (en) 1995-09-27
NZ258610A (en) 1997-05-26
WO1994013656A1 (en) 1994-06-23
CN1227099A (zh) 1999-09-01
CN1094613A (zh) 1994-11-09
US5908860A (en) 1999-06-01
JP2003137880A (ja) 2003-05-14
CA2151515A1 (en) 1994-06-23
JPH08505132A (ja) 1996-06-04
AU5655794A (en) 1994-07-04

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Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
A107 Divisional application of patent
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
G170 Re-publication after modification of scope of protection [patent]
LAPS Lapse due to unpaid annual fee