LV10098B - Methylpiperazinoazepine derivatives, preparation and use thereof - Google Patents

Methylpiperazinoazepine derivatives, preparation and use thereof Download PDF

Info

Publication number
LV10098B
LV10098B LVP-92-398A LV920398A LV10098B LV 10098 B LV10098 B LV 10098B LV 920398 A LV920398 A LV 920398A LV 10098 B LV10098 B LV 10098B
Authority
LV
Latvia
Prior art keywords
methylpiperazin
benzo
pyrido
diazepine
est
Prior art date
Application number
LVP-92-398A
Other languages
English (en)
Latvian (lv)
Other versions
LV10098A (lv
Inventor
Jean-Francois Fernand Liegeois
Jacques Elie Delarge
Original Assignee
Therabel Research Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therabel Research Sa filed Critical Therabel Research Sa
Publication of LV10098A publication Critical patent/LV10098A/xx
Publication of LV10098B publication Critical patent/LV10098B/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
LVP-92-398A 1990-09-26 1992-12-23 Methylpiperazinoazepine derivatives, preparation and use thereof LV10098B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
BE9000914A BE1004596A4 (fr) 1990-09-26 1990-09-26 Derives de methylpiperazinoazepine, leur preparation et leur utilisation.
PCT/BE1991/000073 WO1993007143A1 (fr) 1990-09-26 1991-10-10 Derives de methylpiperazinoazepine, leur preparation et leur utilisation
CA002120229A CA2120229C (fr) 1990-09-26 1991-10-10 Derives de methylpiperazinoazepine, leur preparation et leur utilisation
HK98106195A HK1006970A1 (en) 1990-09-26 1998-06-23 Methylpiperazinoazepine derivatives their preparation and use

Publications (2)

Publication Number Publication Date
LV10098A LV10098A (lv) 1994-05-10
LV10098B true LV10098B (en) 1994-10-20

Family

ID=27159764

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-92-398A LV10098B (en) 1990-09-26 1992-12-23 Methylpiperazinoazepine derivatives, preparation and use thereof

Country Status (14)

Country Link
EP (1) EP0607129B1 (de)
AT (1) ATE126799T1 (de)
BE (1) BE1004596A4 (de)
CA (1) CA2120229C (de)
DE (1) DE69112432T2 (de)
DK (1) DK0607129T3 (de)
EE (1) EE02942B1 (de)
ES (1) ES2080336T3 (de)
GR (1) GR3017951T3 (de)
HK (1) HK1006970A1 (de)
LT (1) LT3231B (de)
LV (1) LV10098B (de)
RU (1) RU2111966C1 (de)
WO (1) WO1993007143A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700445A (en) * 1994-12-12 1997-12-23 Allelix Biopharmaceuticals, Inc. N-methyl piperazine compounds having dopamine receptor affinity
US5561127A (en) * 1994-12-19 1996-10-01 Allelix Biopharmaceuticals, Inc. Muscarinic receptor ligands
FR2850654A1 (fr) * 2003-02-03 2004-08-06 Servier Lab Nouveaux derives d'azepines tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN1913900B (zh) * 2003-12-22 2010-11-24 阿卡蒂亚药品公司 作为毒蕈碱激动剂的氨基取代的二芳基[a，d]环庚烯类似物及神经精神疾病的治疗方法
DE602004020263D1 (de) 2003-12-22 2009-05-07 Acadia Pharm Inc Amino-substituierte diaryläa,dücyclohepten- analoga als muscarinische agonisten und verfahren zur behandlung von neuropsychiatrischen erkrankungen
CN102807574B (zh) * 2011-05-30 2015-09-02 长春吉大天元化学技术股份有限公司 新型吡啶并硫氮七元环衍生物作为抗肿瘤药物、及其制备方法和应用
CN107382907A (zh) * 2017-06-21 2017-11-24 温州医科大学 一种11‑甲基二苯并[b,f][1,4]硒吖庚因化合物及制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7403657A (de) * 1973-03-23 1974-09-25
US3872122A (en) * 1973-04-16 1975-03-18 Bristol Myers Co 11 H-Pyrimido{8 4,5-b{9 {8 1,4{9 benzodiazepines
GB1587128A (en) 1977-04-07 1981-04-01 Hexachimie Benzothiazepine derivatives
IT7851496A0 (it) * 1977-10-31 1978-10-13 Sandoz Ag Menti pirazinobenzossazepine loro preparazione e loro impiego quali medica
CH643263A5 (de) * 1979-05-11 1984-05-30 Sandoz Ag Benzodiazepine, ihre herstellung und verwendung.
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
US4940704A (en) 1989-08-16 1990-07-10 Hoechst-Roussel Pharmaceutical Inc. Pyrido[3,4-b][1,4]benzoxazepines

Also Published As

Publication number Publication date
WO1993007143A1 (fr) 1993-04-15
RU2111966C1 (ru) 1998-05-27
HK1006970A1 (en) 1999-03-26
DE69112432T2 (de) 1996-02-01
DE69112432D1 (de) 1995-09-28
CA2120229A1 (fr) 1993-04-15
EP0607129B1 (de) 1995-08-23
ATE126799T1 (de) 1995-09-15
EP0607129A1 (de) 1994-07-27
EE02942B1 (et) 1996-10-15
GR3017951T3 (en) 1996-02-29
CA2120229C (fr) 2002-04-09
LV10098A (lv) 1994-05-10
LT3231B (en) 1995-04-25
LTIP378A (en) 1994-09-25
BE1004596A4 (fr) 1992-12-22
ES2080336T3 (es) 1996-02-01
DK0607129T3 (da) 1995-12-18

Similar Documents

Publication Publication Date Title
US4062848A (en) Tetracyclic compounds
EP0281459B1 (de) Rechtsdrehendes Enantiomer von alpha-(4,5,6,7-Tetrahydrothieno[3,2-c]pyrid-5-yl)(2-chlorphenyl)methylacetat, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen
EP0587473B1 (de) Kondensierte Pyridin Derivate als Hemmer von Effekten freier Radikaler
FI104076B (fi) Menetelmä farmaseuttisesti vaikuttavien triatsolopyridatsiiniyhdisteiden valmistamiseksi
DK164704B (da) 3,6-disubstituerede triazolo-oe3,4-aaa-ftalazinderivater, fremgangsmaade til fremstilling deraf, udgangsforbindelse til anvendelse i fremgangsmaaden samt anvendelse af og farmaceutisk praeparat indeholdende forbindelserne
US5393752A (en) Methylpiperazinoazepine compounds, preparation and use thereof
CA2468071A1 (fr) Derives de triazolo[4,3-a]pyrido[2,3-d]pyrimidin-5-ones, compositions les contenant, procede de preparation et utilisation
LV10098B (en) Methylpiperazinoazepine derivatives, preparation and use thereof
CS219256B2 (en) Method of making the derivative of the imidazothienpyrimidine
EA002271B1 (ru) ТРИЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ, ОБЛАДАЮЩИЕ АКТИВНОСТЬЮ В ОТНОШЕНИИ ИНТЕГРИНОВ, В ЧАСТНОСТИ В ОТНОШЕНИИ ИНТЕГРИНА АЛЬФАvБЕТА 3, СПОСОБ ИХ ПОЛУЧЕНИЯ И ПРОМЕЖУТОЧНЫЕ СОЕДИНЕНИЯ, ИСПОЛЬЗУЕМЫЕ В ЭТОМ СПОСОБЕ, ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ МЕДИКАМЕНТОВ И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ
DK150157B (da) Analogifremgangsmaade til fremstilling af furo-, thieno- eller pyrrolo (2,3-d)azepiner eller fysiologisk acceptable salte deraf med syrer eller baser
EP0662971B1 (de) 5H,10H-IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZIN-4-ONE DERIVATE, IHRE HERSTELLUNG UND DIE SIE ENTHALTENDEN ARZNEIMITTEL
CZ295992B6 (cs) Beta-karbolinové deriváty, způsob jejich přípravy a farmaceutické prostředky s jejich obsahem
NZ202036A (en) 7-bromo-5-(2-halophenyl)-1h-2,3-dihydro-1,4-benzodiazepine derivatives and pharmaceutical compositions
EP0971928A1 (de) Chinolin-2-on- und dihydrochinolin-2-on-derivate als liganden des rezeptoren 5-ht,5-ht2 und 5-ht1-like
US7053083B2 (en) Cyclohexylphenyl vasopressin agonists
CS203184B2 (en) Process for preparing new pyrroloquinoxalinones and pyrrolobenzodiazepinones
JP2752516B2 (ja) メチルピペラジノアゼピン誘導体およびこれを含有した組成物
EP0499527B1 (de) Beta-carbolinderivate, Ligande für Benzodiazepinrezeptoren mit agonistischer Inverse und Benzodiazepinantasonistische Wirkungen und diese enthaltende Arzneimittel
AU597936B2 (en) Tetracyclic quinazolin derivatives
BRPI0312174B1 (pt) composto, composição farmacêutica, uso de um composto, processo para a preparação de um composto, novo intermediário e processo para a preparação de um novo intermediário
CA2415475C (en) Pyrrolo[2,1-b][1,3]benzothiazepines and their use for the preparation of medicaments with antipsychotic activity
EP0726257B1 (de) 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepinderivative verwendbar zur Behandlung von Erkrankungen des Zentralnervensystems, sowie Benzopyrylium Intermediate zu ihrer Herstellung
JP3128750B2 (ja) １−［２−（置換ビニル）］−５ｈ−２，３−ベンゾジアゼピン誘導体
IE873252L (en) Pyrrole derivatives.