ES2080336T3 - Derivados de metilpiperazinoazepina, su preparacion y su utilizacion. - Google Patents
Derivados de metilpiperazinoazepina, su preparacion y su utilizacion.Info
- Publication number
- ES2080336T3 ES2080336T3 ES91916897T ES91916897T ES2080336T3 ES 2080336 T3 ES2080336 T3 ES 2080336T3 ES 91916897 T ES91916897 T ES 91916897T ES 91916897 T ES91916897 T ES 91916897T ES 2080336 T3 ES2080336 T3 ES 2080336T3
- Authority
- ES
- Spain
- Prior art keywords
- methylpiperazinoazepine
- derivatives
- preparation
- pharmaceutically acceptable
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- LNAMXLRLQJUYFU-UHFFFAOYSA-N 3-methyl-2-piperazin-1-yl-1h-azepine Chemical class N1C=CC=CC(C)=C1N1CCNCC1 LNAMXLRLQJUYFU-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
- C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
- C07D517/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE DESCRIBEN DERIVADOS DE METILPIPERAZINOAZEPINA QUE RESPONDEN A LA FORMULA GENERAL (I), EN LA QUE LOS SIMBOLOS X, R1, R2, N1 Y N2 TIENEN DIFERENTES SIGNIFICACIONES, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, SU PREPARACION Y SU UTILIZACION.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE9000914A BE1004596A4 (fr) | 1990-09-26 | 1990-09-26 | Derives de methylpiperazinoazepine, leur preparation et leur utilisation. |
CA002120229A CA2120229C (fr) | 1990-09-26 | 1991-10-10 | Derives de methylpiperazinoazepine, leur preparation et leur utilisation |
PCT/BE1991/000073 WO1993007143A1 (fr) | 1990-09-26 | 1991-10-10 | Derives de methylpiperazinoazepine, leur preparation et leur utilisation |
HK98106195A HK1006970A1 (en) | 1990-09-26 | 1998-06-23 | Methylpiperazinoazepine derivatives their preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2080336T3 true ES2080336T3 (es) | 1996-02-01 |
Family
ID=27159764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91916897T Expired - Lifetime ES2080336T3 (es) | 1990-09-26 | 1991-10-10 | Derivados de metilpiperazinoazepina, su preparacion y su utilizacion. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0607129B1 (es) |
AT (1) | ATE126799T1 (es) |
BE (1) | BE1004596A4 (es) |
CA (1) | CA2120229C (es) |
DE (1) | DE69112432T2 (es) |
DK (1) | DK0607129T3 (es) |
EE (1) | EE02942B1 (es) |
ES (1) | ES2080336T3 (es) |
GR (1) | GR3017951T3 (es) |
HK (1) | HK1006970A1 (es) |
LT (1) | LT3231B (es) |
LV (1) | LV10098B (es) |
RU (1) | RU2111966C1 (es) |
WO (1) | WO1993007143A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5700445A (en) * | 1994-12-12 | 1997-12-23 | Allelix Biopharmaceuticals, Inc. | N-methyl piperazine compounds having dopamine receptor affinity |
US5561127A (en) * | 1994-12-19 | 1996-10-01 | Allelix Biopharmaceuticals, Inc. | Muscarinic receptor ligands |
FR2850654A1 (fr) * | 2003-02-03 | 2004-08-06 | Servier Lab | Nouveaux derives d'azepines tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
CN1913900B (zh) * | 2003-12-22 | 2010-11-24 | 阿卡蒂亚药品公司 | 作为毒蕈碱激动剂的氨基取代的二芳基[a,d]环庚烯类似物及神经精神疾病的治疗方法 |
KR101157881B1 (ko) | 2003-12-22 | 2012-07-06 | 아카디아 파마슈티칼스 인코포레이티드 | 무스카린 작용제로서의 아미노 치환된 디아릴[a,d]사이클로헵텐 유사체, 및 신경정신 질환의 치료 방법 |
CN102807574B (zh) * | 2011-05-30 | 2015-09-02 | 长春吉大天元化学技术股份有限公司 | 新型吡啶并硫氮七元环衍生物作为抗肿瘤药物、及其制备方法和应用 |
CN107382907A (zh) * | 2017-06-21 | 2017-11-24 | 温州医科大学 | 一种11‑甲基二苯并[b,f][1,4]硒吖庚因化合物及制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7403657A (es) * | 1973-03-23 | 1974-09-25 | ||
US3872122A (en) * | 1973-04-16 | 1975-03-18 | Bristol Myers Co | 11 H-Pyrimido{8 4,5-b{9 {8 1,4{9 benzodiazepines |
GB1587128A (en) | 1977-04-07 | 1981-04-01 | Hexachimie | Benzothiazepine derivatives |
IT7851496A0 (it) * | 1977-10-31 | 1978-10-13 | Sandoz Ag | Menti pirazinobenzossazepine loro preparazione e loro impiego quali medica |
CH643263A5 (de) * | 1979-05-11 | 1984-05-30 | Sandoz Ag | Benzodiazepine, ihre herstellung und verwendung. |
GB8819059D0 (en) * | 1988-08-11 | 1988-09-14 | Lilly Industries Ltd | Benzodiazepine compounds & their use as pharmaceuticals |
US4940704A (en) | 1989-08-16 | 1990-07-10 | Hoechst-Roussel Pharmaceutical Inc. | Pyrido[3,4-b][1,4]benzoxazepines |
-
1990
- 1990-09-26 BE BE9000914A patent/BE1004596A4/fr not_active IP Right Cessation
-
1991
- 1991-10-10 CA CA002120229A patent/CA2120229C/fr not_active Expired - Fee Related
- 1991-10-10 RU RU94021365A patent/RU2111966C1/ru not_active IP Right Cessation
- 1991-10-10 WO PCT/BE1991/000073 patent/WO1993007143A1/fr active IP Right Grant
- 1991-10-10 EP EP91916897A patent/EP0607129B1/fr not_active Expired - Lifetime
- 1991-10-10 AT AT91916897T patent/ATE126799T1/de not_active IP Right Cessation
- 1991-10-10 DE DE69112432T patent/DE69112432T2/de not_active Expired - Fee Related
- 1991-10-10 DK DK91916897.1T patent/DK0607129T3/da active
- 1991-10-10 ES ES91916897T patent/ES2080336T3/es not_active Expired - Lifetime
-
1992
- 1992-12-23 LV LVP-92-398A patent/LV10098B/lv unknown
-
1993
- 1993-03-03 LT LTIP378A patent/LT3231B/lt not_active IP Right Cessation
-
1994
- 1994-10-14 EE EE9400260A patent/EE02942B1/xx not_active IP Right Cessation
-
1995
- 1995-11-01 GR GR950403060T patent/GR3017951T3/el unknown
-
1998
- 1998-06-23 HK HK98106195A patent/HK1006970A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EE02942B1 (et) | 1996-10-15 |
ATE126799T1 (de) | 1995-09-15 |
DE69112432T2 (de) | 1996-02-01 |
LTIP378A (en) | 1994-09-25 |
DE69112432D1 (de) | 1995-09-28 |
WO1993007143A1 (fr) | 1993-04-15 |
CA2120229C (fr) | 2002-04-09 |
BE1004596A4 (fr) | 1992-12-22 |
RU2111966C1 (ru) | 1998-05-27 |
LT3231B (en) | 1995-04-25 |
LV10098B (en) | 1994-10-20 |
DK0607129T3 (da) | 1995-12-18 |
HK1006970A1 (en) | 1999-03-26 |
EP0607129A1 (fr) | 1994-07-27 |
EP0607129B1 (fr) | 1995-08-23 |
CA2120229A1 (fr) | 1993-04-15 |
GR3017951T3 (en) | 1996-02-29 |
LV10098A (lv) | 1994-05-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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