HK1006970A1 - Methylpiperazinoazepine derivatives their preparation and use - Google Patents

Methylpiperazinoazepine derivatives their preparation and use

Info

Publication number
HK1006970A1
HK1006970A1 HK98106195A HK98106195A HK1006970A1 HK 1006970 A1 HK1006970 A1 HK 1006970A1 HK 98106195 A HK98106195 A HK 98106195A HK 98106195 A HK98106195 A HK 98106195A HK 1006970 A1 HK1006970 A1 HK 1006970A1
Authority
HK
Hong Kong
Prior art keywords
methylpiperazinoazepine
derivatives
preparation
pharmaceutically acceptable
general formula
Prior art date
Application number
HK98106195A
Other languages
English (en)
Inventor
Jean-Francois Fernand Liegeois
Jacques Elie Delarge
Original Assignee
Therabel Research Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE9000914A priority Critical patent/BE1004596A4/fr
Priority to DE69112432T priority patent/DE69112432T2/de
Priority to RU94021365A priority patent/RU2111966C1/ru
Priority to AT91916897T priority patent/ATE126799T1/de
Priority to CA002120229A priority patent/CA2120229C/fr
Priority to ES91916897T priority patent/ES2080336T3/es
Priority to DK91916897.1T priority patent/DK0607129T3/da
Priority to EP91916897A priority patent/EP0607129B1/fr
Priority to PCT/BE1991/000073 priority patent/WO1993007143A1/fr
Priority to LVP-92-398A priority patent/LV10098B/lv
Priority to LTIP378A priority patent/LT3231B/lt
Priority to EE9400260A priority patent/EE02942B1/xx
Priority to GR950403060T priority patent/GR3017951T3/el
Application filed by Therabel Research Sa filed Critical Therabel Research Sa
Priority to HK98106195A priority patent/HK1006970A1/xx
Publication of HK1006970A1 publication Critical patent/HK1006970A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
HK98106195A 1990-09-26 1998-06-23 Methylpiperazinoazepine derivatives their preparation and use HK1006970A1 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
BE9000914A BE1004596A4 (fr) 1990-09-26 1990-09-26 Derives de methylpiperazinoazepine, leur preparation et leur utilisation.
EP91916897A EP0607129B1 (fr) 1990-09-26 1991-10-10 Derives de methylpiperazinoazepine, leur preparation et leur utilisation
AT91916897T ATE126799T1 (de) 1990-09-26 1991-10-10 Derivate von methylpiperazinoazepin, verfahren zu ihrer herstellung und verwendung.
CA002120229A CA2120229C (fr) 1990-09-26 1991-10-10 Derives de methylpiperazinoazepine, leur preparation et leur utilisation
ES91916897T ES2080336T3 (es) 1990-09-26 1991-10-10 Derivados de metilpiperazinoazepina, su preparacion y su utilizacion.
DK91916897.1T DK0607129T3 (da) 1990-09-26 1991-10-10 Methylpiperazinoazepinderivater, deres fremstilling og deres anvendelse
PCT/BE1991/000073 WO1993007143A1 (fr) 1990-09-26 1991-10-10 Derives de methylpiperazinoazepine, leur preparation et leur utilisation
DE69112432T DE69112432T2 (de) 1990-09-26 1991-10-10 Derivate von methylpiperazinoazepin, verfahren zu ihrer herstellung und verwendung.
RU94021365A RU2111966C1 (ru) 1990-09-26 1991-10-10 Производные метилпиперазиназепина или фармацевтически приемлемые соли этих производных
LVP-92-398A LV10098B (en) 1990-09-26 1992-12-23 Methylpiperazinoazepine derivatives, preparation and use thereof
LTIP378A LT3231B (en) 1990-09-26 1993-03-03 Methylpiperazinoazepine derivatives, preparation and use tereof
EE9400260A EE02942B1 (et) 1990-09-26 1994-10-14 Metüülpiperasinoasepiini derivaadid, nende valmistamine ja kasutamine
GR950403060T GR3017951T3 (en) 1990-09-26 1995-11-01 Methylpiperazinoazepine derivatives, their preparation and use.
HK98106195A HK1006970A1 (en) 1990-09-26 1998-06-23 Methylpiperazinoazepine derivatives their preparation and use

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
BE9000914A BE1004596A4 (fr) 1990-09-26 1990-09-26 Derives de methylpiperazinoazepine, leur preparation et leur utilisation.
CA002120229A CA2120229C (fr) 1990-09-26 1991-10-10 Derives de methylpiperazinoazepine, leur preparation et leur utilisation
PCT/BE1991/000073 WO1993007143A1 (fr) 1990-09-26 1991-10-10 Derives de methylpiperazinoazepine, leur preparation et leur utilisation
HK98106195A HK1006970A1 (en) 1990-09-26 1998-06-23 Methylpiperazinoazepine derivatives their preparation and use

Publications (1)

Publication Number Publication Date
HK1006970A1 true HK1006970A1 (en) 1999-03-26

Family

ID=27159764

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98106195A HK1006970A1 (en) 1990-09-26 1998-06-23 Methylpiperazinoazepine derivatives their preparation and use

Country Status (14)

Country Link
EP (1) EP0607129B1 (xx)
AT (1) ATE126799T1 (xx)
BE (1) BE1004596A4 (xx)
CA (1) CA2120229C (xx)
DE (1) DE69112432T2 (xx)
DK (1) DK0607129T3 (xx)
EE (1) EE02942B1 (xx)
ES (1) ES2080336T3 (xx)
GR (1) GR3017951T3 (xx)
HK (1) HK1006970A1 (xx)
LT (1) LT3231B (xx)
LV (1) LV10098B (xx)
RU (1) RU2111966C1 (xx)
WO (1) WO1993007143A1 (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700445A (en) * 1994-12-12 1997-12-23 Allelix Biopharmaceuticals, Inc. N-methyl piperazine compounds having dopamine receptor affinity
US5561127A (en) * 1994-12-19 1996-10-01 Allelix Biopharmaceuticals, Inc. Muscarinic receptor ligands
FR2850654A1 (fr) * 2003-02-03 2004-08-06 Servier Lab Nouveaux derives d'azepines tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN1913900B (zh) * 2003-12-22 2010-11-24 阿卡蒂亚药品公司 作为毒蕈碱激动剂的氨基取代的二芳基[a，d]环庚烯类似物及神经精神疾病的治疗方法
US7550454B2 (en) 2003-12-22 2009-06-23 Acadia Pharmaceuticals, Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
CN102807574B (zh) * 2011-05-30 2015-09-02 长春吉大天元化学技术股份有限公司 新型吡啶并硫氮七元环衍生物作为抗肿瘤药物、及其制备方法和应用
CN107382907A (zh) * 2017-06-21 2017-11-24 温州医科大学 一种11‑甲基二苯并[b,f][1,4]硒吖庚因化合物及制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7403657A (xx) * 1973-03-23 1974-09-25
US3872122A (en) * 1973-04-16 1975-03-18 Bristol Myers Co 11 H-Pyrimido{8 4,5-b{9 {8 1,4{9 benzodiazepines
GB1587128A (en) 1977-04-07 1981-04-01 Hexachimie Benzothiazepine derivatives
IT7851496A0 (it) * 1977-10-31 1978-10-13 Sandoz Ag Menti pirazinobenzossazepine loro preparazione e loro impiego quali medica
CH643263A5 (de) * 1979-05-11 1984-05-30 Sandoz Ag Benzodiazepine, ihre herstellung und verwendung.
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
US4940704A (en) 1989-08-16 1990-07-10 Hoechst-Roussel Pharmaceutical Inc. Pyrido[3,4-b][1,4]benzoxazepines

Also Published As

Publication number Publication date
EE02942B1 (et) 1996-10-15
DE69112432T2 (de) 1996-02-01
CA2120229A1 (fr) 1993-04-15
EP0607129B1 (fr) 1995-08-23
LV10098A (lv) 1994-05-10
GR3017951T3 (en) 1996-02-29
LTIP378A (en) 1994-09-25
EP0607129A1 (fr) 1994-07-27
WO1993007143A1 (fr) 1993-04-15
BE1004596A4 (fr) 1992-12-22
ES2080336T3 (es) 1996-02-01
DK0607129T3 (da) 1995-12-18
DE69112432D1 (de) 1995-09-28
LV10098B (en) 1994-10-20
CA2120229C (fr) 2002-04-09
LT3231B (en) 1995-04-25
RU2111966C1 (ru) 1998-05-27
ATE126799T1 (de) 1995-09-15

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20091010