LT4628B - Cefalosporano 7beta-(4-karboksibutanamido)rūgšties fermentinis gavimo būdas, panaudojant modifikuotą trigonopsis variabilis d-aminorūgšties oksidazės fermentą, produkuotą escherichia coli - Google Patents

Cefalosporano 7beta-(4-karboksibutanamido)rūgšties fermentinis gavimo būdas, panaudojant modifikuotą trigonopsis variabilis d-aminorūgšties oksidazės fermentą, produkuotą escherichia coli Download PDF

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Publication number
LT4628B
LT4628B LT99-051A LT99051A LT4628B LT 4628 B LT4628 B LT 4628B LT 99051 A LT99051 A LT 99051A LT 4628 B LT4628 B LT 4628B
Authority
LT
Lithuania
Prior art keywords
enzyme
amino acid
acid oxidase
gene
dna
Prior art date
Application number
LT99-051A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT99051A (en
Inventor
Jose Luis Garcia-Lopez
Estrella Cortes-Rubio
Jorge Alonso-Palacios
Encarnacion Mellado-Duran
Bruno Diez-Garcia
Jose Manuel Guisan-Seijas
Francisco Salto-Maldonado
Jose Luis Barredo-Fuente
Original Assignee
Antibioticos S.A.U.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibioticos S.A.U. filed Critical Antibioticos S.A.U.
Publication of LT99051A publication Critical patent/LT99051A/xx
Publication of LT4628B publication Critical patent/LT4628B/lt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12N9/0024—D-Amino acid oxidase (1.4.3.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LT99-051A 1997-09-25 1999-05-11 Cefalosporano 7beta-(4-karboksibutanamido)rūgšties fermentinis gavimo būdas, panaudojant modifikuotą trigonopsis variabilis d-aminorūgšties oksidazės fermentą, produkuotą escherichia coli LT4628B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009702008A ES2131018B1 (es) 1997-09-25 1997-09-25 Un procedimiento enzimatico para preparar acido 7beta-(4-carboxibutanamido)cefalosporanico utilizando la enzima d-aminoacido oxidasa de trigonopsis variabilis modificada producida en escherichia coli.

Publications (2)

Publication Number Publication Date
LT99051A LT99051A (en) 1999-10-25
LT4628B true LT4628B (lt) 2000-02-25

Family

ID=8300695

Family Applications (1)

Application Number Title Priority Date Filing Date
LT99-051A LT4628B (lt) 1997-09-25 1999-05-11 Cefalosporano 7beta-(4-karboksibutanamido)rūgšties fermentinis gavimo būdas, panaudojant modifikuotą trigonopsis variabilis d-aminorūgšties oksidazės fermentą, produkuotą escherichia coli

Country Status (17)

Country Link
US (1) US6635458B2 (es)
EP (1) EP0969088A1 (es)
JP (1) JP2001506868A (es)
KR (1) KR20000069110A (es)
CN (1) CN1246147A (es)
AU (1) AU9162898A (es)
CA (1) CA2272354A1 (es)
CZ (1) CZ182399A3 (es)
EE (1) EE9900205A (es)
ES (1) ES2131018B1 (es)
HU (1) HUP0000797A2 (es)
IL (1) IL129533A0 (es)
LT (1) LT4628B (es)
LV (1) LV12359B (es)
SK (1) SK64899A3 (es)
WO (1) WO1999015632A1 (es)
ZA (1) ZA988754B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100342014C (zh) * 2004-04-08 2007-10-10 百瑞全球有限公司 重组d－氨基酸氧化酶
CN1912130B (zh) * 2005-08-08 2011-06-15 百瑞全球有限公司 一种用于制备7-氨基头孢霉烷酸的两步酶法
CN101016540B (zh) * 2006-02-10 2010-04-07 台湾尖端先进生技医药股份有限公司 C-端含有组氨酸标记的hoxb4重组蛋白质的制造方法及用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0583817A2 (en) 1992-07-27 1994-02-23 Asahi Kasei Kogyo Kabushiki Kaisha A transformant capable of producing D-amino acid oxidase
JPH071180A (ja) 1993-04-30 1995-01-06 Westinghouse Electric Corp <We> 溶加線材用組成物
ES2109194A1 (es) 1996-04-22 1998-01-01 Antibioticos Sa Un procedimiento para producir la enzima d-aminoacido oxidasa de rhodotorula gracilis en celulas hospedantes.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2268022B1 (es) * 1974-04-22 1977-06-24 Rhone Poulenc Ind
JPS62262994A (ja) * 1986-05-12 1987-11-16 Asahi Chem Ind Co Ltd Ｄ−アミノ酸オキシダ−ゼ遺伝子
CA1340522C (en) * 1987-03-10 1999-05-04 Heinz Dobeli Fusion proteins containing neighbouring histidines for improved purification

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0583817A2 (en) 1992-07-27 1994-02-23 Asahi Kasei Kogyo Kabushiki Kaisha A transformant capable of producing D-amino acid oxidase
JPH071180A (ja) 1993-04-30 1995-01-06 Westinghouse Electric Corp <We> 溶加線材用組成物
ES2109194A1 (es) 1996-04-22 1998-01-01 Antibioticos Sa Un procedimiento para producir la enzima d-aminoacido oxidasa de rhodotorula gracilis en celulas hospedantes.

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KITAMOTO T ET AL.: "Novel missense variants of prion protein in Creutzfeldt-Jakob disease or Gerstmann-Sträussler syndrome.", BIOCHEM BIOPHYS RES COMMUN., 1993, pages 709 - 714, XP024767847, DOI: doi:10.1006/bbrc.1993.1275
SII D, SADANA A.: "Bioseparation using affinity techniques.", J BIOTECHNOL., 1991, pages 83 - 98, XP023944202, DOI: doi:10.1016/0168-1656(91)90076-8

Also Published As

Publication number Publication date
EP0969088A1 (en) 2000-01-05
US6635458B2 (en) 2003-10-21
JP2001506868A (ja) 2001-05-29
KR20000069110A (ko) 2000-11-25
WO1999015632A1 (es) 1999-04-01
CN1246147A (zh) 2000-03-01
AU9162898A (en) 1999-04-12
LV12359A (lv) 1999-10-20
LT99051A (en) 1999-10-25
CZ182399A3 (cs) 1999-09-15
ES2131018B1 (es) 2000-04-01
LV12359B (en) 2000-03-20
IL129533A0 (en) 2000-02-29
EE9900205A (et) 1999-12-15
ZA988754B (en) 1999-06-28
CA2272354A1 (en) 1999-04-01
ES2131018A1 (es) 1999-07-01
SK64899A3 (en) 2000-05-16
US20030119087A1 (en) 2003-06-26
HUP0000797A2 (en) 2000-07-28

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Effective date: 20010924