LT3998B - Endogenous gene expression modification with regulatory element - Google Patents

Endogenous gene expression modification with regulatory element Download PDF

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Publication number
LT3998B
LT3998B LTIP1595A LTIP1595A LT3998B LT 3998 B LT3998 B LT 3998B LT IP1595 A LTIP1595 A LT IP1595A LT IP1595 A LTIP1595 A LT IP1595A LT 3998 B LT3998 B LT 3998B
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LT
Lithuania
Prior art keywords
gene
dna
cell line
genome
segment
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Application number
LTIP1595A
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English (en)
Lithuanian (lt)
Inventor
Scott C Chappel
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Applied Research Systems
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23806064&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3998(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of LTIP1595A publication Critical patent/LTIP1595A/xx
Publication of LT3998B publication Critical patent/LT3998B/lt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • C12N15/902Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/001Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
LTIP1595A 1989-12-22 1993-12-15 Endogenous gene expression modification with regulatory element LT3998B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45478389A 1989-12-22 1989-12-22

Publications (2)

Publication Number Publication Date
LTIP1595A LTIP1595A (en) 1995-07-25
LT3998B true LT3998B (en) 1996-06-25

Family

ID=23806064

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1595A LT3998B (en) 1989-12-22 1993-12-15 Endogenous gene expression modification with regulatory element

Country Status (26)

Country Link
EP (5) EP1484412A3 (es)
JP (3) JP3501286B2 (es)
KR (1) KR0176693B1 (es)
AR (1) AR245776A1 (es)
AT (2) ATE156189T1 (es)
AU (1) AU645294B2 (es)
BG (1) BG60624B1 (es)
BR (1) BR9007937A (es)
CA (1) CA2071989C (es)
DE (3) DE69031172T2 (es)
DK (2) DK0505500T3 (es)
ES (2) ES2104690T3 (es)
FI (1) FI107391B (es)
GR (1) GR3025057T3 (es)
HK (2) HK1000547A1 (es)
HU (1) HU217212B (es)
IL (4) IL116046A (es)
LT (1) LT3998B (es)
LV (1) LV10655B (es)
NO (1) NO311896B1 (es)
OA (1) OA09594A (es)
RO (1) RO109864B1 (es)
RU (1) RU2128227C1 (es)
UA (1) UA42675C2 (es)
WO (1) WO1991009955A1 (es)
ZA (1) ZA9010392B (es)

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