LT3398B - Process for preparing deacylated 10-baccatine iii - Google Patents

Process for preparing deacylated 10-baccatine iii Download PDF

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Publication number
LT3398B
LT3398B LTIP1397A LTIP1397A LT3398B LT 3398 B LT3398 B LT 3398B LT IP1397 A LTIP1397 A LT IP1397A LT IP1397 A LTIP1397 A LT IP1397A LT 3398 B LT3398 B LT 3398B
Authority
LT
Lithuania
Prior art keywords
process according
deacetyl
ether
baccatin iii
butyl
Prior art date
Application number
LTIP1397A
Other languages
English (en)
Lithuanian (lt)
Inventor
Jean-Claude Gaullier
Bernadette Mandard
Rodolphe Margraff
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of LTIP1397A publication Critical patent/LTIP1397A/xx
Publication of LT3398B publication Critical patent/LT3398B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Fats And Perfumes (AREA)
  • Pyrane Compounds (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Compounds Of Unknown Constitution (AREA)
LTIP1397A 1992-10-05 1993-10-04 Process for preparing deacylated 10-baccatine iii LT3398B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9211746A FR2696463B1 (fr) 1992-10-05 1992-10-05 Procédé d'obtention de la désacétyl-10 baccatine III.

Publications (2)

Publication Number Publication Date
LTIP1397A LTIP1397A (en) 1994-11-25
LT3398B true LT3398B (en) 1995-09-25

Family

ID=9434124

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1397A LT3398B (en) 1992-10-05 1993-10-04 Process for preparing deacylated 10-baccatine iii

Country Status (30)

Country Link
US (1) US5393895A (es)
EP (1) EP0663910B1 (es)
JP (1) JP3299754B2 (es)
KR (1) KR100301236B1 (es)
CN (1) CN1043530C (es)
AT (1) ATE148883T1 (es)
AU (1) AU680629B2 (es)
CA (1) CA2146373C (es)
CZ (2) CZ284615B6 (es)
DE (1) DE69308155T2 (es)
DK (1) DK0663910T3 (es)
EE (1) EE03126B1 (es)
ES (1) ES2098061T3 (es)
FI (1) FI109794B (es)
FR (1) FR2696463B1 (es)
GE (1) GEP20001937B (es)
GR (1) GR3022617T3 (es)
HU (1) HU226862B1 (es)
LT (1) LT3398B (es)
LV (1) LV10621B (es)
MX (1) MX9305771A (es)
NO (1) NO310413B1 (es)
NZ (1) NZ256450A (es)
PL (1) PL177316B1 (es)
RU (1) RU2107065C1 (es)
SK (1) SK280949B6 (es)
TW (1) TW255890B (es)
UA (1) UA44227C2 (es)
WO (1) WO1994007882A1 (es)
ZA (1) ZA937313B (es)

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FR2696462B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé d'obtention de la désacétyl-10 baccatine III.
DE69435342D1 (de) 1993-07-19 2011-05-05 Angiotech Pharm Inc Anti-Angiogene Mittel und Verfahren zu deren Verwendung
ES2144533T3 (es) * 1993-11-02 2000-06-16 Rhone Poulenc Rorer Gmbh Procedimiento para la separacion de una mezcla.
FR2714053B1 (fr) * 1993-12-22 1996-03-08 Pf Medicament Procédé d'extraction et d'isolement de la 10-désacétylbaccatine III.
CN1112433A (zh) * 1994-05-24 1995-11-29 郭明 红豆杉属植物提取物及其应用
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FR2736355B1 (fr) * 1995-07-07 1997-11-07 Pf Medicament Procede d'extraction et d'isolement de la 10-desacetylbaccatine iii
US5750736A (en) * 1996-07-11 1998-05-12 Napro Biotherapeutics, Inc. Method for acylating 10-deacetylbaccatin III selectively at the c-10 position
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US6002024A (en) * 1998-07-27 1999-12-14 Dabur Research Foundation Process for the isolation of 14β-hydroxy-10-deacetyl baccatin-III
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US7351542B2 (en) 2002-05-20 2008-04-01 The Regents Of The University Of California Methods of modulating tubulin deacetylase activity
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US9956385B2 (en) 2012-06-28 2018-05-01 The Spectranetics Corporation Post-processing of a medical device to control morphology and mechanical properties
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AU2013341711A1 (en) 2012-11-12 2015-05-21 Redwood Bioscience, Inc. Compounds and methods for producing a conjugate
CN103804326A (zh) * 2012-11-15 2014-05-21 刘胜远 一种从含10-去乙酰基巴卡亭ⅲ的浸膏分离和提纯10-去乙酰基巴卡亭ⅲ的方法
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MX2021000644A (es) 2018-07-18 2021-08-19 Manzanita Pharmaceuticals Inc Conjugados para suministrar un agente contra el cancer a las celulas nerviosas, metodos de uso y metodos para la elaboracion de los mismos.
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CN110317183B (zh) * 2019-08-08 2021-03-12 无锡紫杉药业有限公司 一种红豆杉天然提取产物的纯化方法
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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4814470A (en) 1986-07-17 1989-03-21 Rhone-Poulenc Sante Taxol derivatives, their preparation and pharmaceutical compositions containing them
US4924012A (en) 1988-04-06 1990-05-08 Rhone-Poulenc Sante Process for preparing derivatives of baccatine III and of 10-deacetyl baccatine III
US4924011A (en) 1988-04-06 1990-05-08 Centre National De La Recherche Scientifique Process for preparing taxol
EP0400971A2 (en) 1989-05-31 1990-12-05 Florida State University Method for preparation of taxol
EP0428376A1 (en) 1989-11-14 1991-05-22 Florida State University Method for preparation of taxol using an oxazinone
WO1992009589A1 (fr) 1990-11-23 1992-06-11 Rhone-Poulenc Rorer S.A. Procede de preparation de derives du taxane, nouveaux derives obtenus et compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

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Publication number Priority date Publication date Assignee Title
US5380916A (en) 1990-11-02 1995-01-10 University Of Florida Method for the isolation and purification of taxane derivatives
JP3222466B2 (ja) * 1991-04-19 2001-10-29 ザ・ユニバーシティ・オブ・ミシシッピー タクサン類を単離するための方法および組成物
IT1258838B (it) 1992-01-31 1996-02-29 Indena Spa Processo per l'estrazione di tassolo e derivati da cultivar del genere taxus

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4814470A (en) 1986-07-17 1989-03-21 Rhone-Poulenc Sante Taxol derivatives, their preparation and pharmaceutical compositions containing them
US4924012A (en) 1988-04-06 1990-05-08 Rhone-Poulenc Sante Process for preparing derivatives of baccatine III and of 10-deacetyl baccatine III
US4924011A (en) 1988-04-06 1990-05-08 Centre National De La Recherche Scientifique Process for preparing taxol
EP0400971A2 (en) 1989-05-31 1990-12-05 Florida State University Method for preparation of taxol
EP0428376A1 (en) 1989-11-14 1991-05-22 Florida State University Method for preparation of taxol using an oxazinone
WO1992009589A1 (fr) 1990-11-23 1992-06-11 Rhone-Poulenc Rorer S.A. Procede de preparation de derives du taxane, nouveaux derives obtenus et compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
SK280949B6 (sk) 2000-09-12
EP0663910B1 (fr) 1997-02-12
NO310413B1 (no) 2001-07-02
FR2696463B1 (fr) 1994-11-25
DK0663910T3 (da) 1997-03-10
LV10621A (lv) 1995-04-20
GR3022617T3 (en) 1997-05-31
JPH08501792A (ja) 1996-02-27
ZA937313B (en) 1994-04-25
PL308244A1 (en) 1995-07-24
KR100301236B1 (ko) 2001-11-22
LV10621B (en) 1995-10-20
DE69308155T2 (de) 1997-08-07
SK43395A3 (en) 1995-08-09
FI109794B (fi) 2002-10-15
MX9305771A (es) 1994-05-31
EP0663910A1 (fr) 1995-07-26
WO1994007882A1 (fr) 1994-04-14
CZ284615B6 (cs) 1999-01-13
CA2146373A1 (fr) 1994-04-14
AU5115593A (en) 1994-04-26
CN1043530C (zh) 1999-06-02
KR950703550A (ko) 1995-09-20
ATE148883T1 (de) 1997-02-15
LTIP1397A (en) 1994-11-25
GEP20001937B (en) 2000-02-05
CZ287065B6 (cs) 2000-08-16
AU680629B2 (en) 1997-08-07
NZ256450A (en) 1996-11-26
CN1085551A (zh) 1994-04-20
PL177316B1 (pl) 1999-10-29
FI951596A0 (fi) 1995-04-04
HU226862B1 (en) 2009-12-28
FR2696463A1 (fr) 1994-04-08
FI951596A (fi) 1995-04-04
HUT72449A (en) 1996-04-29
EE03126B1 (et) 1998-10-15
DE69308155D1 (de) 1997-03-27
ES2098061T3 (es) 1997-04-16
UA44227C2 (uk) 2002-02-15
JP3299754B2 (ja) 2002-07-08
RU95110687A (ru) 1996-12-27
US5393895A (en) 1995-02-28
NO951282L (no) 1995-04-03
TW255890B (es) 1995-09-01
CZ84595A3 (en) 1995-09-13
RU2107065C1 (ru) 1998-03-20
CA2146373C (fr) 2006-08-29
NO951282D0 (no) 1995-04-03
HU9500973D0 (en) 1995-06-28

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Owner name: AVENTIS PHARMA S.A., FR

Effective date: 20041206

MK9A Expiry of a patent

Effective date: 20131004