KR960016206B1 - Bu-3862t 항종양 항생제 - Google Patents

Bu-3862t 항종양 항생제 Download PDF

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Publication number
KR960016206B1
KR960016206B1 KR1019890002806A KR890002806A KR960016206B1 KR 960016206 B1 KR960016206 B1 KR 960016206B1 KR 1019890002806 A KR1019890002806 A KR 1019890002806A KR 890002806 A KR890002806 A KR 890002806A KR 960016206 B1 KR960016206 B1 KR 960016206B1
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KR
South Korea
Prior art keywords
formula
strain
dihydro
diacetyl
medium
Prior art date
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Expired - Fee Related
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KR1019890002806A
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English (en)
Korean (ko)
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KR890014102A (ko
Inventor
스가와라 고꼬
하또리 마사미
가메이 히데오
고니시 마사따까
오끼 도시까즈
도미따 고지
Original Assignee
브리스톨-마이어즈 스퀴브 컴페니
아이삭 자아코브스키
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Application filed by 브리스톨-마이어즈 스퀴브 컴페니, 아이삭 자아코브스키 filed Critical 브리스톨-마이어즈 스퀴브 컴페니
Publication of KR890014102A publication Critical patent/KR890014102A/ko
Application granted granted Critical
Publication of KR960016206B1 publication Critical patent/KR960016206B1/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/55—Streptomyces hygroscopicus

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Epoxy Compounds (AREA)
  • Saccharide Compounds (AREA)
KR1019890002806A 1988-03-07 1989-03-07 Bu-3862t 항종양 항생제 Expired - Fee Related KR960016206B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US165,337 1988-03-07
US07/165,337 US4912133A (en) 1988-03-07 1988-03-07 BU-3862T antitumor antibiotic

Publications (2)

Publication Number Publication Date
KR890014102A KR890014102A (ko) 1989-10-21
KR960016206B1 true KR960016206B1 (ko) 1996-12-06

Family

ID=22598495

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890002806A Expired - Fee Related KR960016206B1 (ko) 1988-03-07 1989-03-07 Bu-3862t 항종양 항생제

Country Status (17)

Country Link
US (1) US4912133A (enExample)
EP (1) EP0332080B1 (enExample)
JP (1) JP2821756B2 (enExample)
KR (1) KR960016206B1 (enExample)
AT (1) ATE76406T1 (enExample)
AU (1) AU618790B2 (enExample)
CA (1) CA1338184C (enExample)
DE (1) DE68901552D1 (enExample)
DK (1) DK173937B1 (enExample)
ES (1) ES2036729T3 (enExample)
FI (1) FI90991C (enExample)
GR (1) GR3004756T3 (enExample)
IE (1) IE62211B1 (enExample)
IL (1) IL89477A (enExample)
NO (1) NO174432C (enExample)
PT (1) PT89917B (enExample)
ZA (1) ZA891695B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071957A (en) * 1989-08-04 1991-12-10 Bristol-Myers Company Antibiotic BU-4061T
EP1463719A2 (en) 2002-01-08 2004-10-06 Eisai Co., Ltd Eponemycin and epoxomicin analogs and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474800A (en) * 1980-05-13 1984-10-02 Taisho Pharmaceutical Co., Ltd. Epoxysuccinyl amino acid derivatives
JPS5865287A (ja) * 1981-10-14 1983-04-18 Nippon Chemiphar Co Ltd ベーターアミノアルコール誘導体と，心筋梗塞の予防および治療剤
JPS58116412A (ja) * 1981-12-29 1983-07-11 Taisho Pharmaceut Co Ltd 直腸投与製剤
JPS608223A (ja) * 1983-06-28 1985-01-17 Taisho Pharmaceut Co Ltd 抗アレルギ−剤

Also Published As

Publication number Publication date
IL89477A0 (en) 1989-09-10
IE62211B1 (en) 1995-01-11
JP2821756B2 (ja) 1998-11-05
IL89477A (en) 1994-11-28
DK107189D0 (da) 1989-03-06
JPH0272167A (ja) 1990-03-12
ES2036729T3 (es) 1993-06-01
FI891001L (fi) 1989-09-08
CA1338184C (en) 1996-03-26
PT89917B (pt) 1994-05-31
GR3004756T3 (enExample) 1993-04-28
DK173937B1 (da) 2002-02-25
IE890724L (en) 1989-09-07
ZA891695B (en) 1989-11-29
ATE76406T1 (de) 1992-06-15
NO890944D0 (no) 1989-03-06
EP0332080B1 (en) 1992-05-20
DK107189A (da) 1989-09-08
FI90991C (fi) 1994-04-25
NO890944L (no) 1989-09-08
FI891001A0 (fi) 1989-03-02
DE68901552D1 (de) 1992-06-25
AU3104189A (en) 1989-09-07
NO174432C (no) 1998-06-09
PT89917A (pt) 1989-11-10
FI90991B (fi) 1994-01-14
AU618790B2 (en) 1992-01-09
US4912133A (en) 1990-03-27
KR890014102A (ko) 1989-10-21
NO174432B (no) 1994-01-24
EP0332080A1 (en) 1989-09-13

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