KR960013435B1 - 바이러스 억제제 및 dsRNA를 함유하는 바이러스 감염질환 및 HIV 감염질환 치료용 조성물 - Google Patents

바이러스 억제제 및 dsRNA를 함유하는 바이러스 감염질환 및 HIV 감염질환 치료용 조성물 Download PDF

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Publication number
KR960013435B1
KR960013435B1 KR1019880003033A KR880003033A KR960013435B1 KR 960013435 B1 KR960013435 B1 KR 960013435B1 KR 1019880003033 A KR1019880003033 A KR 1019880003033A KR 880003033 A KR880003033 A KR 880003033A KR 960013435 B1 KR960013435 B1 KR 960013435B1
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South Korea
Prior art keywords
dsrna
aids
hiv
mismatched
virus
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Expired - Fee Related
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KR1019880003033A
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English (en)
Korean (ko)
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KR880010777A (ko
Inventor
에이. 카터 윌리암
Original Assignee
헤미스페르스 바이오파마, 인코오포레이티드
로이 디. 우르다노프
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
KR1019880003033A 1987-03-23 1988-03-22 바이러스 억제제 및 dsRNA를 함유하는 바이러스 감염질환 및 HIV 감염질환 치료용 조성물 Expired - Fee Related KR960013435B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US2882387A 1987-03-23 1987-03-23
US028,823 1987-03-23
US028823 1987-03-23
US125097 1987-11-25
US07/125,097 US4950652A (en) 1987-03-23 1987-11-25 dsRNAs for combination therapy in the treatment of viral diseases
US125,097 1987-11-25

Publications (2)

Publication Number Publication Date
KR880010777A KR880010777A (ko) 1988-10-24
KR960013435B1 true KR960013435B1 (ko) 1996-10-05

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KR1019880003033A Expired - Fee Related KR960013435B1 (ko) 1987-03-23 1988-03-22 바이러스 억제제 및 dsRNA를 함유하는 바이러스 감염질환 및 HIV 감염질환 치료용 조성물

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US (1) US4950652A (enExample)
EP (1) EP0286224B1 (enExample)
JP (1) JP2656938B2 (enExample)
KR (1) KR960013435B1 (enExample)
CN (1) CN1049357C (enExample)
AU (1) AU1256288A (enExample)
CA (1) CA1316832C (enExample)
DE (1) DE3876125T2 (enExample)
DK (1) DK156688A (enExample)
ES (1) ES2066782T3 (enExample)
FI (1) FI881305L (enExample)
GR (1) GR3006340T3 (enExample)
HU (1) HUT46542A (enExample)
IE (1) IE63823B1 (enExample)
IL (1) IL85646A (enExample)
NO (1) NO881246L (enExample)
NZ (1) NZ223868A (enExample)
OA (1) OA08724A (enExample)
PH (1) PH23333A (enExample)
PT (1) PT87039B (enExample)
RU (1) RU2016572C1 (enExample)

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US5834443A (en) * 1996-05-21 1998-11-10 Masiello; Domenick J. Composition and method for treating herpes simplex
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FR2766711B1 (fr) * 1997-08-04 2001-02-02 Sod Conseils Rech Applic Produit comprenant au moins un arn double brin en association avec au moins un devire du 6-benzyluracile pour une utilisation therapeutique simultanee, separee ou etalee dans le temps
FR2766715B1 (fr) * 1997-08-04 2001-02-16 Scras Produit comprenant au moins de l'arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique simultanee, separee ou etalee dans le temps, dans le traitement d'une maladie virale
AR013269A1 (es) * 1997-08-04 2000-12-13 Scras Producto que contiene por lo menos un rna de doble filamento combinado con por lo menos un agente anti-viral, para la utilizacion terapeutica en eltratamiento de una enfermedad viral, en especial de la hepatitis viral
FR2768344B1 (fr) * 1997-08-26 2001-02-16 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale
FR2768345B1 (fr) * 1997-09-17 2001-05-04 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale, notamment d'une hepatite virale
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
KR20010042069A (ko) 1998-03-20 2001-05-25 베니텍 오스트레일리아 리미티드 유전자 발현 조절방법
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
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US6977245B2 (en) 1999-04-12 2005-12-20 The United States Of America As Represented By The Department Of Health And Human Services Oligodeoxynucleotide and its use to induce an immune response
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RU2172631C2 (ru) * 1999-10-08 2001-08-27 Государственный научный центр вирусологии и биотехнологии "Вектор" Индуктор интерферона пролонгированного действия
DE60131430T2 (de) 2000-01-14 2008-10-16 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Oligodeoxynukleotide und ihre verwendung zur induktion einer immunreaktion
US7638496B2 (en) 2000-02-15 2009-12-29 Valeant Pharmaceuticals North America Nucleoside analogs with carboxamidine modified monocyclic base
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US20020132257A1 (en) 2001-01-31 2002-09-19 Tony Giordano Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
US7666674B2 (en) 2001-07-27 2010-02-23 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo
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WO2003051301A2 (en) * 2001-12-14 2003-06-26 Hemispherx Biopharma USE OF dsRNAs IN STRATEGIC THERAPEUTIC INTERVENTION OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY
US8466116B2 (en) 2001-12-20 2013-06-18 The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of CpG oligodeoxynucleotides to induce epithelial cell growth
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Also Published As

Publication number Publication date
NO881246L (no) 1988-09-26
NO881246D0 (no) 1988-03-21
PH23333A (en) 1989-07-14
KR880010777A (ko) 1988-10-24
IE880839L (en) 1988-09-23
EP0286224A2 (en) 1988-10-12
PT87039B (pt) 1992-11-30
CA1316832C (en) 1993-04-27
ES2066782T3 (es) 1995-03-16
FI881305A7 (fi) 1988-09-24
DK156688D0 (da) 1988-03-22
PT87039A (pt) 1988-04-01
IE63823B1 (en) 1995-06-14
FI881305A0 (fi) 1988-03-18
HUT46542A (en) 1988-11-28
OA08724A (fr) 1989-03-31
IL85646A (en) 1993-05-13
GR3006340T3 (enExample) 1993-06-21
US4950652A (en) 1990-08-21
DE3876125T2 (de) 1993-06-09
IL85646A0 (en) 1988-08-31
JP2656938B2 (ja) 1997-09-24
EP0286224A3 (en) 1988-12-07
CN88101606A (zh) 1988-12-28
FI881305L (fi) 1988-09-24
AU1256288A (en) 1988-09-22
RU2016572C1 (ru) 1994-07-30
NZ223868A (en) 1991-02-26
DK156688A (da) 1988-09-24
JPS6425A (en) 1989-01-05
EP0286224B1 (en) 1992-11-25
CN1049357C (zh) 2000-02-16
DE3876125D1 (de) 1993-01-07

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Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20031006

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000