EP0998293A4 - Cytokine related treatments of disease - Google Patents
Cytokine related treatments of diseaseInfo
- Publication number
- EP0998293A4 EP0998293A4 EP98903474A EP98903474A EP0998293A4 EP 0998293 A4 EP0998293 A4 EP 0998293A4 EP 98903474 A EP98903474 A EP 98903474A EP 98903474 A EP98903474 A EP 98903474A EP 0998293 A4 EP0998293 A4 EP 0998293A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- disease
- related treatments
- cytokine related
- cytokine
- treatments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03008818A EP1329220A1 (en) | 1997-01-17 | 1998-01-13 | Cytokine related treatments of disease |
EP02021843A EP1277759A1 (en) | 1997-01-17 | 1998-01-13 | Cytokine related treatments of disease |
EP00118252A EP1103559A1 (en) | 1997-01-17 | 1998-01-13 | Autoimmune nucleosides |
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3609497P | 1997-01-17 | 1997-01-17 | |
US36094P | 1997-01-17 | ||
US4397497P | 1997-04-23 | 1997-04-23 | |
US2858697P | 1997-04-23 | 1997-04-23 | |
US28586P | 1997-04-23 | ||
US43974P | 1997-04-23 | ||
US5548797P | 1997-08-12 | 1997-08-12 | |
US55487P | 1997-08-12 | ||
PCT/US1998/000634 WO1998030223A1 (en) | 1997-01-17 | 1998-01-13 | Cytokine related treatments of disease |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00118252A Division EP1103559A1 (en) | 1997-01-17 | 1998-01-13 | Autoimmune nucleosides |
EP03008818A Division EP1329220A1 (en) | 1997-01-17 | 1998-01-13 | Cytokine related treatments of disease |
EP02021843A Division EP1277759A1 (en) | 1997-01-17 | 1998-01-13 | Cytokine related treatments of disease |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0998293A1 EP0998293A1 (en) | 2000-05-10 |
EP0998293A4 true EP0998293A4 (en) | 2002-07-17 |
Family
ID=27487693
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98903474A Withdrawn EP0998293A4 (en) | 1997-01-17 | 1998-01-13 | Cytokine related treatments of disease |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0998293A4 (en) |
JP (3) | JP2002515892A (en) |
KR (1) | KR20000070167A (en) |
CN (3) | CN1253504A (en) |
AU (1) | AU736075B2 (en) |
BR (1) | BR9807473A (en) |
CA (1) | CA2278158A1 (en) |
HU (1) | HUP0001526A3 (en) |
IL (1) | IL130497A0 (en) |
NO (3) | NO993439L (en) |
PL (1) | PL336579A1 (en) |
SI (1) | SI9820003A (en) |
SK (1) | SK94099A3 (en) |
WO (1) | WO1998030223A1 (en) |
YU (1) | YU61598A (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6455690B1 (en) * | 1996-10-16 | 2002-09-24 | Robert Tam | L-8-oxo-7-propyl-7,8-dihydro-(9H)-guanosine |
MY164523A (en) | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
CN101099745A (en) | 2000-05-26 | 2008-01-09 | 艾登尼科斯(开曼)有限公司 | Methods and compositions for treating flaviviruses and pestiviruses |
US6680059B2 (en) | 2000-08-29 | 2004-01-20 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
RU2286172C2 (en) | 2000-08-17 | 2006-10-27 | Трипеп Аб | Ribavirin-containing vaccines and methods for their application |
AU2001292151B2 (en) | 2000-08-17 | 2006-05-04 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
US20050182252A1 (en) | 2004-02-13 | 2005-08-18 | Reddy K. R. | Novel 2'-C-methyl nucleoside derivatives |
CN1989439B (en) * | 2004-05-06 | 2010-12-29 | 美国政府健康及人类服务部 | Methods and compositions for the treatment of uveitis |
SE534514C2 (en) * | 2006-03-14 | 2011-09-20 | Wholesome Biopharm Pty Ltd | Composition for the treatment of allergic diseases |
US8071561B2 (en) | 2007-08-16 | 2011-12-06 | Chrontech Pharma Ab | Immunogen platform |
SG11201702430WA (en) * | 2014-09-26 | 2017-04-27 | Riboscience Llc | 4'-vinyl substituted nucleoside derivatives as inhibitors of respiratory syncytial virus rna replication |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0346132A1 (en) * | 1988-06-10 | 1989-12-13 | The Regents Of The University Of Minnesota | Pharmaceutical products |
US5290540A (en) * | 1991-05-01 | 1994-03-01 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Method for treating infectious respiratory diseases |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4950652A (en) * | 1987-03-23 | 1990-08-21 | Hem Research, Inc. | dsRNAs for combination therapy in the treatment of viral diseases |
-
1998
- 1998-01-13 IL IL13049798A patent/IL130497A0/en unknown
- 1998-01-13 PL PL98336579A patent/PL336579A1/en unknown
- 1998-01-13 CA CA002278158A patent/CA2278158A1/en not_active Abandoned
- 1998-01-13 WO PCT/US1998/000634 patent/WO1998030223A1/en not_active Application Discontinuation
- 1998-01-13 BR BR9807473A patent/BR9807473A/en unknown
- 1998-01-13 KR KR1019997006393A patent/KR20000070167A/en not_active Application Discontinuation
- 1998-01-13 SK SK940-99A patent/SK94099A3/en unknown
- 1998-01-13 EP EP98903474A patent/EP0998293A4/en not_active Withdrawn
- 1998-01-13 AU AU60238/98A patent/AU736075B2/en not_active Ceased
- 1998-01-13 HU HU0001526A patent/HUP0001526A3/en unknown
- 1998-01-13 CN CN98801801A patent/CN1253504A/en active Pending
- 1998-01-13 SI SI9820003A patent/SI9820003A/en not_active IP Right Cessation
- 1998-01-13 YU YU61598A patent/YU61598A/en unknown
- 1998-01-13 JP JP53124598A patent/JP2002515892A/en active Pending
-
1999
- 1999-07-13 NO NO993439A patent/NO993439L/en not_active Application Discontinuation
-
2000
- 2000-07-22 CN CN00121912A patent/CN1312254A/en active Pending
- 2000-08-29 CN CN00126807A patent/CN1289594A/en active Pending
- 2000-08-31 NO NO20004327A patent/NO20004327D0/en unknown
- 2000-08-31 NO NO20004329A patent/NO20004329D0/en not_active Application Discontinuation
-
2001
- 2001-05-24 JP JP2001155321A patent/JP2002080490A/en active Pending
-
2003
- 2003-04-21 JP JP2003115258A patent/JP2004035546A/en not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0346132A1 (en) * | 1988-06-10 | 1989-12-13 | The Regents Of The University Of Minnesota | Pharmaceutical products |
US5290540A (en) * | 1991-05-01 | 1994-03-01 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Method for treating infectious respiratory diseases |
Non-Patent Citations (1)
Title |
---|
See also references of WO9830223A1 * |
Also Published As
Publication number | Publication date |
---|---|
NO993439D0 (en) | 1999-07-13 |
JP2002515892A (en) | 2002-05-28 |
NO20004327D0 (en) | 2000-08-31 |
JP2002080490A (en) | 2002-03-19 |
IL130497A0 (en) | 2000-06-01 |
AU6023898A (en) | 1998-08-03 |
KR20000070167A (en) | 2000-11-25 |
YU61598A (en) | 2003-02-28 |
NO20004329D0 (en) | 2000-08-31 |
HUP0001526A3 (en) | 2002-10-28 |
CN1312254A (en) | 2001-09-12 |
EP0998293A1 (en) | 2000-05-10 |
NO20004327L (en) | 1999-09-13 |
WO1998030223A1 (en) | 1998-07-16 |
CN1253504A (en) | 2000-05-17 |
NO20004329L (en) | 1999-09-13 |
PL336579A1 (en) | 2000-07-03 |
SK94099A3 (en) | 2001-06-11 |
NO993439L (en) | 1999-09-13 |
CA2278158A1 (en) | 1998-07-16 |
HUP0001526A2 (en) | 2001-05-28 |
CN1289594A (en) | 2001-04-04 |
JP2004035546A (en) | 2004-02-05 |
SI9820003A (en) | 1999-06-30 |
BR9807473A (en) | 2000-03-21 |
AU736075B2 (en) | 2001-07-26 |
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Legal Events
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Owner name: RIBAPHARM, INC. |
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