KR950700065A - 진해제(Antitussive) - Google Patents

진해제(Antitussive)

Info

Publication number
KR950700065A
KR950700065A KR1019940702877A KR19940702877A KR950700065A KR 950700065 A KR950700065 A KR 950700065A KR 1019940702877 A KR1019940702877 A KR 1019940702877A KR 19940702877 A KR19940702877 A KR 19940702877A KR 950700065 A KR950700065 A KR 950700065A
Authority
KR
South Korea
Prior art keywords
carbon atoms
hydrogen
formula
alkyl
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
KR1019940702877A
Other languages
English (en)
Korean (ko)
Inventor
히로시 나가세
쥰조오 카메이
코오지 카와이
타카시 엔도오
Original Assignee
마에다 카쭈노수케
토오레 카부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 마에다 카쭈노수케, 토오레 카부시키가이샤 filed Critical 마에다 카쭈노수케
Publication of KR950700065A publication Critical patent/KR950700065A/ko
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Linear Motors (AREA)
  • Fats And Perfumes (AREA)
KR1019940702877A 1992-12-22 1993-12-22 진해제(Antitussive) Abandoned KR950700065A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP34194792 1992-12-22
JP92-341947? 1992-12-22
PCT/JP1993/001855 WO1994014445A1 (fr) 1992-12-22 1993-12-22 Antitussif

Publications (1)

Publication Number Publication Date
KR950700065A true KR950700065A (ko) 1995-01-16

Family

ID=18349997

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940702877A Abandoned KR950700065A (ko) 1992-12-22 1993-12-22 진해제(Antitussive)

Country Status (11)

Country Link
US (1) US5714483A (enExample)
EP (1) EP0636371B1 (enExample)
KR (1) KR950700065A (enExample)
CN (1) CN1071117C (enExample)
AT (1) ATE166229T1 (enExample)
AU (1) AU674379B2 (enExample)
CA (1) CA2130457A1 (enExample)
DE (1) DE69318710T2 (enExample)
NO (1) NO307496B1 (enExample)
TW (1) TW366284B (enExample)
WO (1) WO1994014445A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU712012B2 (en) * 1995-09-26 1999-10-28 Toray Industries, Inc. Indole derivatives and medical application thereof
EP0894799B1 (en) * 1997-01-16 2004-04-07 Toray Industries, Inc. Indolomorphinane derivatives and remedies/preventives for cerebral disorders
EP0998928A4 (en) * 1997-07-09 2002-10-24 Toray Industries Cough medium
KR20020012314A (ko) * 1999-07-19 2002-02-15 히라이 가쯔히꼬 빈뇨 혹은 요실금의 치료 또는 예방제
PL368612A1 (en) * 2001-08-14 2005-04-04 Biotie Therapies Corporation Method of treating alcoholism or alcohol abuse
EP1522542A1 (en) * 2002-07-11 2005-04-13 Toray Industries, Inc. Therapeutic or preventive agent for nausea/vomiting
TW200633721A (en) * 2004-12-14 2006-10-01 Shionogi & Co A pharmaceutical composition for treating constipation
CN101355943A (zh) * 2005-10-11 2009-01-28 东丽株式会社 呕气和/或呕吐治疗药
JPWO2008001859A1 (ja) * 2006-06-30 2009-11-26 学校法人北里研究所 オピオイドδ受容体アゴニスト

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613668A (en) * 1983-12-22 1986-09-23 The United States Of America As Represented By The Department Of Health And Human Services Short total synthesis or morphinan compounds which uses cyclization of a cycloalkylcarbonyl compound selected from cyclopropylcarbonyl and cyclobutylcarbonyl
US4816586A (en) * 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
PT95069B (pt) * 1989-08-24 1997-10-31 Searle & Co Processo para a preparacao de (+)-isomeros de derivados de endoetano/endoetanoepoximofinano, uteis como agentes anti-tussicos
JP2906654B2 (ja) * 1989-11-28 1999-06-21 東レ株式会社 免疫抑制剤及びその製造方法
AU654275B2 (en) * 1991-04-30 1994-11-03 Ur Labs, Inc. Method for reducing emesis and nausea induced by the administration of an emesis-causing agent
JPH04342529A (ja) * 1991-05-21 1992-11-30 Toray Ind Inc 抗アレルギー剤

Also Published As

Publication number Publication date
US5714483A (en) 1998-02-03
EP0636371A1 (en) 1995-02-01
DE69318710T2 (de) 1998-09-10
CA2130457A1 (en) 1994-07-07
EP0636371A4 (enExample) 1995-03-01
WO1994014445A1 (fr) 1994-07-07
NO943070L (no) 1994-10-21
CN1099617A (zh) 1995-03-08
DE69318710D1 (en) 1998-06-25
TW366284B (en) 1999-08-11
NO943070D0 (no) 1994-08-19
NO307496B1 (no) 2000-04-17
ATE166229T1 (de) 1998-06-15
AU5715694A (en) 1994-07-19
EP0636371B1 (en) 1998-05-20
CN1071117C (zh) 2001-09-19
AU674379B2 (en) 1996-12-19

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 19940819

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19981214

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20000830

Patent event code: PE09021S01D

AMND Amendment
E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20010728

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20000830

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

Patent event date: 20010828

Comment text: Request for Trial against Decision on Refusal

Patent event code: PJ02012R01D

Patent event date: 20010728

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20011207

Appeal identifier: 2001101002873

Request date: 20010828

PB0901 Examination by re-examination before a trial

Comment text: Request for Trial against Decision on Refusal

Patent event date: 20010828

Patent event code: PB09011R01I

Comment text: Amendment to Specification, etc.

Patent event date: 20010130

Patent event code: PB09011R02I

B701 Decision to grant
PB0701 Decision of registration after re-examination before a trial

Patent event date: 20011207

Comment text: Decision to Grant Registration

Patent event code: PB07012S01D

Patent event date: 20011112

Comment text: Transfer of Trial File for Re-examination before a Trial

Patent event code: PB07011S01I

NORF Unpaid initial registration fee
PC1904 Unpaid initial registration fee