ATE166229T1 - Antitussivum - Google Patents
AntitussivumInfo
- Publication number
- ATE166229T1 ATE166229T1 AT94903039T AT94903039T ATE166229T1 AT E166229 T1 ATE166229 T1 AT E166229T1 AT 94903039 T AT94903039 T AT 94903039T AT 94903039 T AT94903039 T AT 94903039T AT E166229 T1 ATE166229 T1 AT E166229T1
- Authority
- AT
- Austria
- Prior art keywords
- antitussive
- delta
- image
- acceptable salt
- active ingredient
- Prior art date
Links
- 230000000954 anitussive effect Effects 0.000 title abstract 2
- 229940124584 antitussives Drugs 0.000 title abstract 2
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 title 1
- 230000000694 effects Effects 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000000857 delta opiate receptor antagonist Substances 0.000 abstract 1
- PCHPORCSPXIHLZ-UHFFFAOYSA-N diphenhydramine hydrochloride Chemical compound [Cl-].C=1C=CC=CC=1C(OCC[NH+](C)C)C1=CC=CC=C1 PCHPORCSPXIHLZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000001771 impaired effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Fats And Perfumes (AREA)
- Linear Motors (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34194792 | 1992-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE166229T1 true ATE166229T1 (de) | 1998-06-15 |
Family
ID=18349997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94903039T ATE166229T1 (de) | 1992-12-22 | 1993-12-22 | Antitussivum |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5714483A (de) |
| EP (1) | EP0636371B1 (de) |
| KR (1) | KR950700065A (de) |
| CN (1) | CN1071117C (de) |
| AT (1) | ATE166229T1 (de) |
| AU (1) | AU674379B2 (de) |
| CA (1) | CA2130457A1 (de) |
| DE (1) | DE69318710T2 (de) |
| NO (1) | NO307496B1 (de) |
| TW (1) | TW366284B (de) |
| WO (1) | WO1994014445A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69628543T2 (de) * | 1995-09-26 | 2003-12-11 | Toray Industries, Inc. | Indolderivate und ihre medizinische verwendung |
| WO1998031684A1 (en) * | 1997-01-16 | 1998-07-23 | Toray Industries, Inc. | Indolomorphinane derivatives and remedies/preventives for cerebral disorders |
| CA2264928A1 (en) * | 1997-07-09 | 1999-01-21 | Koji Kawai | Antitussives |
| CA2379577A1 (en) * | 1999-07-19 | 2001-01-25 | Toray Industries, Inc. | Remedies or preventives for frequent urination or urinary incontinence |
| EP1423116A1 (de) * | 2001-08-14 | 2004-06-02 | Biotie Therapies Corp. | Verfahren zur behandlung von alkoholismus oder alkoholmissbrauch |
| EP1522542A1 (de) * | 2002-07-11 | 2005-04-13 | Toray Industries, Inc. | Therapeutisches bzw. prophylaktisches mittel gegen übelkeit/ erbrechen |
| EP1844792A4 (de) * | 2004-12-14 | 2008-05-21 | Shionogi & Co | Therapeutisches mittel gegen obstipation |
| CA2625495A1 (en) * | 2005-10-11 | 2007-04-19 | Toray Industries, Inc. | Therapeutic agent for nausea and/or vomiting |
| JPWO2008001859A1 (ja) * | 2006-06-30 | 2009-11-26 | 学校法人北里研究所 | オピオイドδ受容体アゴニスト |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4613668A (en) * | 1983-12-22 | 1986-09-23 | The United States Of America As Represented By The Department Of Health And Human Services | Short total synthesis or morphinan compounds which uses cyclization of a cycloalkylcarbonyl compound selected from cyclopropylcarbonyl and cyclobutylcarbonyl |
| US4816586A (en) * | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
| PT95069B (pt) * | 1989-08-24 | 1997-10-31 | Searle & Co | Processo para a preparacao de (+)-isomeros de derivados de endoetano/endoetanoepoximofinano, uteis como agentes anti-tussicos |
| JP2906654B2 (ja) * | 1989-11-28 | 1999-06-21 | 東レ株式会社 | 免疫抑制剤及びその製造方法 |
| AU654275B2 (en) * | 1991-04-30 | 1994-11-03 | Ur Labs, Inc. | Method for reducing emesis and nausea induced by the administration of an emesis-causing agent |
| JPH04342529A (ja) * | 1991-05-21 | 1992-11-30 | Toray Ind Inc | 抗アレルギー剤 |
-
1993
- 1993-12-22 AT AT94903039T patent/ATE166229T1/de not_active IP Right Cessation
- 1993-12-22 AU AU57156/94A patent/AU674379B2/en not_active Ceased
- 1993-12-22 DE DE69318710T patent/DE69318710T2/de not_active Expired - Fee Related
- 1993-12-22 CA CA002130457A patent/CA2130457A1/en not_active Abandoned
- 1993-12-22 KR KR1019940702877A patent/KR950700065A/ko not_active Abandoned
- 1993-12-22 WO PCT/JP1993/001855 patent/WO1994014445A1/ja not_active Ceased
- 1993-12-22 US US08/290,837 patent/US5714483A/en not_active Expired - Fee Related
- 1993-12-22 CN CN93119935A patent/CN1071117C/zh not_active Expired - Fee Related
- 1993-12-22 EP EP94903039A patent/EP0636371B1/de not_active Expired - Lifetime
-
1994
- 1994-01-21 TW TW083100512A patent/TW366284B/zh active
- 1994-08-19 NO NO943070A patent/NO307496B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2130457A1 (en) | 1994-07-07 |
| AU5715694A (en) | 1994-07-19 |
| NO943070D0 (no) | 1994-08-19 |
| EP0636371B1 (de) | 1998-05-20 |
| WO1994014445A1 (fr) | 1994-07-07 |
| CN1071117C (zh) | 2001-09-19 |
| EP0636371A1 (de) | 1995-02-01 |
| TW366284B (en) | 1999-08-11 |
| KR950700065A (ko) | 1995-01-16 |
| CN1099617A (zh) | 1995-03-08 |
| NO943070L (no) | 1994-10-21 |
| EP0636371A4 (de) | 1995-03-01 |
| US5714483A (en) | 1998-02-03 |
| NO307496B1 (no) | 2000-04-17 |
| DE69318710D1 (en) | 1998-06-25 |
| DE69318710T2 (de) | 1998-09-10 |
| AU674379B2 (en) | 1996-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |