KR940010864B1 - 말 및 개의 인터페론의 제조방법 - Google Patents

말 및 개의 인터페론의 제조방법 Download PDF

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Publication number
KR940010864B1
KR940010864B1 KR1019850009607A KR850009607A KR940010864B1 KR 940010864 B1 KR940010864 B1 KR 940010864B1 KR 1019850009607 A KR1019850009607 A KR 1019850009607A KR 850009607 A KR850009607 A KR 850009607A KR 940010864 B1 KR940010864 B1 KR 940010864B1
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South Korea
Prior art keywords
dna
plasmid
interferon
fragment
sequences
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Expired - Fee Related
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KR1019850009607A
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English (en)
Korean (ko)
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KR860005020A (ko
Inventor
히믈러 아돌프
하웁트만 루돌프
하우엘 노르베르트
아돌프 귄테르
스웨틀리 피터
Original Assignee
베링거 인겔하임 인터네셔날 게엠베하
디이터 라우디엔, 루돌프 호프만
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Application filed by 베링거 인겔하임 인터네셔날 게엠베하, 디이터 라우디엔, 루돌프 호프만 filed Critical 베링거 인겔하임 인터네셔날 게엠베하
Publication of KR860005020A publication Critical patent/KR860005020A/ko
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1019850009607A 1984-12-18 1985-12-18 말 및 개의 인터페론의 제조방법 Expired - Fee Related KR940010864B1 (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DEP3446124.8 1984-12-18
DE3446122 1984-12-18
DEP3446122.1 1984-12-18
DE3446124 1984-12-18
DE3529262 1985-08-16
DEP3529262.8 1985-08-16
DE3535115 1985-10-02
DEP3535115.2 1985-10-02

Publications (2)

Publication Number Publication Date
KR860005020A KR860005020A (ko) 1986-07-16
KR940010864B1 true KR940010864B1 (ko) 1994-11-18

Family

ID=27433247

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850009607A Expired - Fee Related KR940010864B1 (ko) 1984-12-18 1985-12-18 말 및 개의 인터페론의 제조방법

Country Status (19)

Country Link
US (2) US5605688A (enExample)
EP (1) EP0186098B1 (enExample)
JP (1) JPH0753596A (enExample)
KR (1) KR940010864B1 (enExample)
AT (1) ATE77410T1 (enExample)
AU (1) AU604634B2 (enExample)
CA (1) CA1339954C (enExample)
DE (1) DE3544520C2 (enExample)
DK (1) DK167929B1 (enExample)
ES (1) ES8704515A1 (enExample)
FI (1) FI90990C (enExample)
GR (1) GR853062B (enExample)
HU (1) HU212836B (enExample)
IE (1) IE58685B1 (enExample)
IL (1) IL77369A (enExample)
NO (1) NO176057C (enExample)
NZ (1) NZ214602A (enExample)
PT (1) PT81691B (enExample)
WO (1) WO1986003775A1 (enExample)

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FI90990C (fi) * 1984-12-18 1994-04-25 Boehringer Ingelheim Int Rekombinantti-DNA-molekyyli, transformoitu isäntäorganismi ja menetelmä interferonin valmistamiseksi
DE3642096A1 (de) * 1986-12-10 1988-06-16 Boehringer Ingelheim Int Pferde-(gamma)-interferon
DE3932311A1 (de) * 1989-09-28 1991-04-11 Boehringer Ingelheim Int Verfahren zur reinigung von beta-interferon
US6482403B1 (en) 1998-05-29 2002-11-19 Heska Corporation Caniney IL-13 immunoregulatory proteins and uses thereof
USRE40374E1 (en) 1998-05-29 2008-06-10 Heska Corporation Canine IL-13 immunoregulatory proteins and uses thereof
US20020127200A1 (en) 1998-05-29 2002-09-12 Shumin Yang Canine and feline immunoregulatory proteins, nucleic acid molecules, and uses thereof
AU4102099A (en) 1998-05-29 1999-12-13 Heska Corporation Canine Interleukin -4 Proteins, Nucleic Acid Molecules, and Uses Thereof
EA004789B9 (ru) 1998-10-16 2017-05-31 Байоджен, Инк. Полимерные конъюгаты бета-1а-интерферона и их использование
EP1450836A4 (en) * 2000-11-03 2007-07-25 Intarcia Therapeutics Inc PROCESS FOR SHORT AND LONG-TERM DOSAGE OF MEDICAMENTS
KR20040053291A (ko) * 2001-11-09 2004-06-23 바이오메디신즈 인코포레이티드 오메가 인터페론을 이용한 질환 치료 방법
US20040072236A1 (en) * 2002-09-27 2004-04-15 Neil Cashman PrPSc -interacting molecules and uses thereof
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
DE602007009377D1 (de) 2006-05-30 2010-11-04 Intarcia Therapeutics Inc Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem
EP2359808B1 (en) 2006-08-09 2013-05-22 Intarcia Therapeutics, Inc Osmotic delivery systems and piston assemblies
CN104000779A (zh) 2007-04-23 2014-08-27 精达制药公司 促胰岛素释放肽的混悬制剂及其应用
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
NO2462246T3 (enExample) 2009-09-28 2018-02-03
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
PL2686002T3 (pl) 2011-03-15 2018-10-31 Biogen Ma Inc. Sposób łagodzenia symptomów grypopodobnych związanych z domięśniowym podawaniem interferonu przy wykorzystaniu schematu zwiększania dawki z szybkim miareczkowaniem
CN102321169A (zh) * 2011-09-30 2012-01-18 长春工业大学 一种犬重组干扰素α及制备方法
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
US10925639B2 (en) 2015-06-03 2021-02-23 Intarcia Therapeutics, Inc. Implant placement and removal systems
TWI754643B (zh) 2016-05-16 2022-02-11 美商因塔希亞治療公司 升糖素受體選擇性多肽和彼之使用方法
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
WO2018129058A1 (en) 2017-01-03 2018-07-12 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a glp-1 receptor agonist and co-adminstration of a drug
CN108486127A (zh) * 2018-01-12 2018-09-04 中国农业科学院北京畜牧兽医研究所 犬干扰素-α6α7重组蛋白及其制备方法与应用
CN108424915A (zh) * 2018-01-12 2018-08-21 中国农业科学院北京畜牧兽医研究所 犬干扰素-α2重组蛋白的制备方法
CN108912222B (zh) * 2018-08-02 2020-06-19 中国农业科学院北京畜牧兽医研究所 一种重组犬干扰素CaIFN-λ及其应用
GB202011945D0 (en) * 2020-07-31 2020-09-16 Ilc Therapeutics Ltd Compositions and methods relating to the treatment of diseases
CN112079912B (zh) * 2020-09-25 2022-05-06 广州源博医药科技有限公司 一种高活性的犬α干扰素重组蛋白及其制备方法和应用

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Publication number Priority date Publication date Assignee Title
WO1980002375A1 (en) * 1977-09-23 1980-11-13 Hem Res Inc High purity animal interferons
US4262090A (en) * 1979-06-04 1981-04-14 Cetus Corporation Interferon production
ZA811368B (en) * 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
DE3176011D1 (en) * 1980-06-12 1987-04-23 Japan Found Cancer Plasmid
US4436815A (en) * 1981-11-27 1984-03-13 Eli Lilly And Company Method for stabilizing and selecting recombinant DNA containing host cells
IE54592B1 (en) * 1982-03-08 1989-12-06 Genentech Inc Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby
IL68561A (en) * 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
JPS60118196A (ja) * 1983-11-30 1985-06-25 Takeda Chem Ind Ltd インタ−フェロンの製造法
US4606917A (en) * 1984-10-03 1986-08-19 Syntex (U.S.A) Inc. Synergistic antiviral composition
FI90990C (fi) * 1984-12-18 1994-04-25 Boehringer Ingelheim Int Rekombinantti-DNA-molekyyli, transformoitu isäntäorganismi ja menetelmä interferonin valmistamiseksi
US4689224A (en) * 1985-10-07 1987-08-25 Neogen Corporation Method for administering vaccines containing equine leukokines and compositions therefor

Also Published As

Publication number Publication date
DE3544520A1 (de) 1986-12-18
PT81691A (de) 1986-01-01
NO176057B (no) 1994-10-17
EP0186098A1 (de) 1986-07-02
DE3544520C2 (de) 1995-07-20
HUT40165A (en) 1986-11-28
NO855078L (no) 1986-06-19
ES550043A0 (es) 1987-04-01
WO1986003775A1 (fr) 1986-07-03
DK586585D0 (da) 1985-12-17
ES8704515A1 (es) 1987-04-01
CA1339954C (en) 1998-07-14
FI90990C (fi) 1994-04-25
US5605688A (en) 1997-02-25
JPH0753596A (ja) 1995-02-28
IE853194L (en) 1986-06-18
NZ214602A (en) 1991-06-25
AU604634B2 (en) 1991-01-03
KR860005020A (ko) 1986-07-16
AU5132085A (en) 1986-06-26
EP0186098B1 (de) 1992-06-17
GR853062B (enExample) 1986-04-21
FI854994L (fi) 1986-06-19
DK167929B1 (da) 1994-01-03
HU212836B (en) 1996-12-30
IL77369A (en) 1993-07-08
US5798228A (en) 1998-08-25
NO176057C (no) 1995-01-25
FI854994A0 (fi) 1985-12-16
FI90990B (fi) 1994-01-14
DK586585A (da) 1986-06-19
PT81691B (pt) 1988-04-21
IE58685B1 (en) 1994-02-09
ATE77410T1 (de) 1992-07-15

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